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7 条记录 (耗时 0.018 秒)

    Selectively absorbable/biodegradable, fibrous composite constructs and applications thereof
    5.
    发明授权
    Selectively absorbable/biodegradable, fibrous composite constructs and applications thereof 有权
    选择性吸收/可生物降解的纤维复合结构及其应用

    公开(公告)号：US09011439B2

    公开(公告)日：2015-04-21

    申请号：US11983321

    申请日：2007-11-08

    申请人： Shalaby W. Shalaby ,  Shawn Peniston ,  Kimberly A. Carpenter

    发明人： Shalaby W. Shalaby ,  Shawn Peniston ,  Kimberly A. Carpenter

    IPC分类号： A61B17/04 ,  A61B17/56 ,  A61L27/48 ,  A61L27/58 ,  C08L23/06

    CPC分类号： A61L27/48 ,  A61L27/54 ,  A61L27/58 ,  C08L23/06 ,  C08L2203/12 ,  C08L67/04

    摘要： A family of selectively absorbable/biodegradable, fibrous composite constructs includes different combinations of biostable and absorbable/biodegradable yarns assembled as initially interdependent, load-bearing components, transitioning to exhibit independent functional properties during in vivo end-use. The family of constructs consists of two groups, one group is made of fiber-reinforced composites of high compliance, absorbable matrices of segmented polyaxial copolyesters reinforced with multifilament yarn constructs, which are combinations of ultrahigh molecular weight polyethylene fibers and at least one absorbable/biodegradable fiber selected from silk fibers and multifilament yarns made from linear segmented, l-lactide copolyesters and poly (3-hydroxyalkanoates, are useful in orthopedic, maxillofacial, urological, vascular, hernial repair and tissue engineering applications. The second group is made of coated and uncoated, warp-knitted mesh constructs for use in hernial, vascular, and urological tissue repair and tissue engineering.

    摘要翻译： 一系列可选择性吸收/可生物降解的纤维复合材料构造包括生物稳定和可吸收/可生物降解的纱线的不同组合，其组装为最初相互依赖的承载组分，在体内最终用途中转变为显示独立的功能特性。 构建体组由两组组成，一组由高柔顺性的纤维增强复合材料制成，由多丝纱构造物增强的分段多轴共聚酯的可吸收基质，其是超高分子量聚乙烯纤维和至少一种可吸收/可生物降解的组合 纤维选自由线性分段的丙交酯共聚酯和聚（3-羟基链烷酸酯）制成的丝纤维和复丝纱，可用于矫形，颌面，泌尿，血管，疝修补和组织工程应用中，第二组由涂层和 用于疝，血管和泌尿组织修复和组织工程的无涂层，经编网眼构造物。

    Selectively absorbable/biodegradable, fibrous composite constructs and applications thereof
    6.
    发明申请
    Selectively absorbable/biodegradable, fibrous composite constructs and applications thereof 有权
    选择性吸收/可生物降解的纤维复合结构及其应用

    公开(公告)号：US20080119848A1

    公开(公告)日：2008-05-22

    申请号：US11983321

    申请日：2007-11-08

    申请人： Shalaby W. Shalaby ,  Shawn Peniston ,  Kimberly A. Carpenter

    发明人： Shalaby W. Shalaby ,  Shawn Peniston ,  Kimberly A. Carpenter

    IPC分类号： A61B17/04 ,  A61B17/56

    CPC分类号： A61L27/48 ,  A61L27/54 ,  A61L27/58 ,  C08L23/06 ,  C08L2203/12 ,  C08L67/04

    摘要： A family of selectively absorbable/biodegradable, fibrous composite constructs includes different combinations of biostable and absorbable/biodegradable yarns assembled as initially interdependent, load-bearing components, transitioning to exhibit independent functional properties during in vivo end-use. The family of constructs consists of two groups, one group is made of fiber-reinforced composites of high compliance, absorbable matrices of segmented polyaxial copolyesters reinforced with multifilament yarn constructs, which are combinations of ultrahigh molecular weight polyethylene fibers and at least one absorbable/biodegradable fiber selected from silk fibers and multifilament yarns made from linear segmented, l-lactide copolyesters and poly (3-hydroxyalkanoates, are useful in orthopedic, maxillofacial, urological, vascular, hernial repair and tissue engineering applications. The second group is made of coated and uncoated, warp-knitted mesh constructs for use in hernial, vascular, and urological tissue repair and tissue engineering.

    摘要翻译： 一系列可选择性吸收/可生物降解的纤维复合材料构造包括生物稳定和可吸收/可生物降解的纱线的不同组合，其组装为最初相互依赖的承载组分，在体内最终用途中转变为显示独立的功能特性。 构建体组由两组组成，一组由高柔顺性的纤维增强复合材料制成，由多丝纱构造物增强的分段多轴共聚酯的可吸收基质，其是超高分子量聚乙烯纤维和至少一种可吸收/可生物降解的组合 纤维选自由线性分段的丙交酯共聚酯和聚（3-羟基链烷酸酯）制成的丝纤维和复丝纱，可用于矫形，颌面，泌尿，血管，疝修补和组织工程应用中，第二组由涂层和 用于疝，血管和泌尿组织修复和组织工程的无涂层，经编网眼构造物。

    Inorganic-organic melted-extruded hybrid filaments and medical applications thereof
    7.
    发明授权
    Inorganic-organic melted-extruded hybrid filaments and medical applications thereof 有权
    无机 - 有机熔融挤出杂化丝及其医疗应用

    公开(公告)号：US07465489B2

    公开(公告)日：2008-12-16

    申请号：US11599691

    申请日：2006-11-15

    申请人： Shalaby W Shalaby ,  Kenneth W Clinkscales ,  Kimberly A. Carpenter

    发明人： Shalaby W Shalaby ,  Kenneth W Clinkscales ,  Kimberly A. Carpenter

    IPC分类号： B32B25/02 ,  C04B32/33

    CPC分类号： D01F1/10 ,  A61L17/10 ,  A61L31/128 ,  A61L31/18 ,  Y10T428/249938 ,  Y10T428/2913 ,  Y10T428/2927 ,  Y10T428/298

    摘要： This invention deals with a family of inorganic-organic hybrid, melt-extruded filaments having variable cross-sectional geometry with a cross-sectional area ranging between 100 μ2 and 4 mm2, wherein the inorganic component comprises at least 10 weight percent of the total system and is present as dispersed micro-/nanoparticles in an organic absorbable or non-absorbable matrix representing no more than 90 weight percent. Hybrid filaments are particularly useful for the production of absorbable/disintegratable coil components of an absorbable/disintegratable endoureteral stent and radiopaque surgical markers or sutures.

    摘要翻译： 本发明涉及一种无机 - 有机杂化物，具有横截面积可变的横截面几何形状的熔体挤出长丝，横截面积在100平方毫米至4平方毫米之间，其中无机成分占总体系的至少10重量％ 并且作为分散的微/纳米颗粒存在于不超过90重量％的有机可吸收或不可吸收的基质中。 混合细丝特别可用于生产可吸收/可分解的输尿​​管支架和不透射线外科标记物或缝合线的可吸收/可分解的线圈组件。