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24 条记录 (耗时 0.024 秒)

    Inorganic-organic melted-extruded hybrid filaments and medical applications thereof
    2.
    发明授权
    Inorganic-organic melted-extruded hybrid filaments and medical applications thereof 有权
    无机 - 有机熔融挤出杂化丝及其医疗应用

    公开(公告)号：US07465489B2

    公开(公告)日：2008-12-16

    申请号：US11599691

    申请日：2006-11-15

    申请人： Shalaby W Shalaby ,  Kenneth W Clinkscales ,  Kimberly A. Carpenter

    发明人： Shalaby W Shalaby ,  Kenneth W Clinkscales ,  Kimberly A. Carpenter

    IPC分类号： B32B25/02 ,  C04B32/33

    CPC分类号： D01F1/10 ,  A61L17/10 ,  A61L31/128 ,  A61L31/18 ,  Y10T428/249938 ,  Y10T428/2913 ,  Y10T428/2927 ,  Y10T428/298

    摘要： This invention deals with a family of inorganic-organic hybrid, melt-extruded filaments having variable cross-sectional geometry with a cross-sectional area ranging between 100 μ2 and 4 mm2, wherein the inorganic component comprises at least 10 weight percent of the total system and is present as dispersed micro-/nanoparticles in an organic absorbable or non-absorbable matrix representing no more than 90 weight percent. Hybrid filaments are particularly useful for the production of absorbable/disintegratable coil components of an absorbable/disintegratable endoureteral stent and radiopaque surgical markers or sutures.

    摘要翻译： 本发明涉及一种无机 - 有机杂化物，具有横截面积可变的横截面几何形状的熔体挤出长丝，横截面积在100平方毫米至4平方毫米之间，其中无机成分占总体系的至少10重量％ 并且作为分散的微/纳米颗粒存在于不超过90重量％的有机可吸收或不可吸收的基质中。 混合细丝特别可用于生产可吸收/可分解的输尿​​管支架和不透射线外科标记物或缝合线的可吸收/可分解的线圈组件。

    Self-setting absorbable composites and applications thereof
    7.
    发明授权
    Self-setting absorbable composites and applications thereof 有权
    自制可吸收复合材料及其应用

    公开(公告)号：US08034850B2

    公开(公告)日：2011-10-11

    申请号：US11601994

    申请日：2006-11-20

    申请人： Shalaby W Shalaby ,  Michael Aaron Vaughn

    发明人： Shalaby W Shalaby ,  Michael Aaron Vaughn

    IPC分类号： A61K6/083 ,  C08K3/32 ,  A61K33/42

    CPC分类号： A61K6/0038 ,  A61K6/0017 ,  A61K6/083 ,  A61L24/0084 ,  C08L33/00

    摘要： Self-setting, bioactive, absorbable composites are derived from inorganic phosphate microparticles and a cyanoacrylate matrix of a methoxypropyl cyanoacrylate at a weight to volume ratio of at least 20/80 of microparticles/matrix. The self-setting composites are capable of the controlled release of bone mineralizing ions, antimicrobials, and bone growth promoters. Such composites are useful as bone cements, fillers, and/or substitutes.

    摘要翻译： 自制，生物活性，可吸收的复合材料衍生自无机磷酸盐微粒和氰基丙烯酸甲氧基丙酯的氰基丙烯酸酯基质，体积比至少为20/80微米/基质。 自固化复合材料能够控制骨矿化离子，抗微生物剂和骨生长促进剂的释放。 这样的复合材料可用作骨水泥，填料和/或替代物。

    Intravaginal ringed mesh device and applicator therefor
    9.
    发明授权
    Intravaginal ringed mesh device and applicator therefor 有权
    阴道环网装置及其施用器

    公开(公告)号：US08057817B2

    公开(公告)日：2011-11-15

    申请号：US11667933

    申请日：2005-12-14

    申请人： Shalaby W Shalaby

    发明人： Shalaby W Shalaby

    IPC分类号： A61F13/02

    CPC分类号： A61K9/0036 ,  A61F6/142

    摘要： This invention generally covers a ringed-mesh intravaginal device and applicator therefore wherein the ringed-mesh comprises a composite ring comprising a flexible matrix containing one or more bioactive agent or agents and needed excipients or modulators, and the said matrix is reinforced with a fibrous construct to provided needed initial and in-use biomechanical stability. Of special application of the medicated, ringed-mesh is its use for securing contraception relying on biomechanical, pharmacological, and biochemical means.

    摘要翻译： 本发明通常涵盖环形网状阴道内装置和施用器，其中环形网包括复合环，复合环包含含有一种或多种生物活性剂或试剂和所需赋形剂或调节剂的柔性基质，所述基质用纤维结构 以提供所需的初始和使用中的生物力学稳定性。 特殊应用的戒药网是用于依靠生物力学，药理学和生化手段确保避孕方法。

    Composite vascular constructs with selectively controlled properties
    10.
    发明授权
    Composite vascular constructs with selectively controlled properties 有权
    具有选择性控制性质的复合血管构建体

    公开(公告)号：US07371256B2

    公开(公告)日：2008-05-13

    申请号：US10735063

    申请日：2003-12-12

    申请人： Shalaby W Shalaby

    发明人： Shalaby W Shalaby

    IPC分类号： A61F2/06 ,  A61F13/00

    CPC分类号： A61F2/06

    摘要： This invention deals with a composite vascular construct, which is formed of a first, blood contacting component and a second, tissue contacting component. Preferably, the present vascular constructs are in the form of a vascular patch or vascular graft with surface-activated, non-absorbable fabric with immobilized biomolecules on the blood contacting surface, and an absorbable, compliant film or microporous sheath on the other surface of the non-absorbable component of the composite graft or patch.

    摘要翻译： 本发明涉及由第一血液接触组分和第二组织接触组分形成的复合血管构建体。 优选地，本发明的血管构建体是具有在血液接触表面上具有固定的生物分子的具有表面活化的不可吸收的织物的血管斑块或血管移植物的形式，以及在所述血液接触表面的另一表面上的可吸收的柔顺膜或微孔护套 复合移植物或补片的不可吸收组分。