公开(公告)号：US20120215153A1

公开(公告)日：2012-08-23

申请号：US13503234

申请日：2010-10-22

申请人： Kohei Fukaya ,  Ryoji Nakano ,  Hidekazu Miyauchi

发明人： Kohei Fukaya ,  Ryoji Nakano ,  Hidekazu Miyauchi

IPC分类号： A61F9/00

CPC分类号： A61F9/00772

摘要： A tube device for insertion into a lacrimal passage, optimized according to the structure of a lacrimal passage and capable of being operated without impairing the functional effect of a lacrimal passage endoscope. A tube device for insertion into a lacrimal passage comprises a pair of tubes to be placed in the lacrimal passage. Openings are formed at both ends of the pair of tubes. A reinforcement body is disposed and held in the vicinity of each opening at a position located at a predetermined distance from the opening.

摘要翻译： 用于插入泪道的管装置，根据泪道的结构进行优化，能够在不损伤泪道内窥镜的功能效果的情况下进行操作。 用于插入泪道的管装置包括一对待放置在泪道中的管。 开口形成在一对管的两端。 加强体被设置并保持在位于距开口预定距离的位置处的每个开口附近。

公开(公告)号：US20110084019A1

公开(公告)日：2011-04-14

申请号：US12934712

申请日：2009-03-26

申请人： Seimei Shiratori ,  Oriha Kuwaki ,  Jin-Ho Kim ,  Kohei Fukaya ,  Tsuyoshi Mihayashi

发明人： Seimei Shiratori ,  Oriha Kuwaki ,  Jin-Ho Kim ,  Kohei Fukaya ,  Tsuyoshi Mihayashi

IPC分类号： A61L33/00 ,  B32B3/00 ,  B32B33/00 ,  B32B37/24

CPC分类号： A61L33/062 ,  A61L27/34 ,  A61L29/085 ,  A61L31/10 ,  Y10T428/24355

摘要： Provided is a surface showing excellent antithrombotic properties. Also provided is a medical device having the same. An antithrombotic surface comprising polymer layers which are in different charged states and alternately layered, characterized by having three-dimensional peaks and valleys formed thereon. The antithrombotic surface as described above which is further characterized in that the peaks and valleys are 15 nm or more but not more than 200 nm in height and depth respectively. A medical device characterized by being provided with the antithrombotic surface as described above. Thus, a thin and highly antithrombotic surface or medical device can be obtained by a relatively convenient method.

摘要翻译： 提供了表现出优异抗血栓性质的表面。 还提供了具有该装置的医疗装置。 一种抗血栓表面，其包含处于不同带电状态并交替层叠的聚合物层，其特征在于其上形成有三维峰和谷。 如上所述的抗血栓表面，其特征还在于，峰和谷的高度和深度分别为15nm以上且不大于200nm。 一种医疗装置，其特征在于具有如上所述的抗血栓表面。 因此，可以通过相对方便的方法获得薄且高抗血栓表面或医疗装置。

公开(公告)号：US20090076484A1

公开(公告)日：2009-03-19

申请号：US11577794

申请日：2005-10-19

申请人： Kohei Fukaya

发明人： Kohei Fukaya

IPC分类号： A61M25/09 ,  A61M25/098

CPC分类号： A61M25/0068 ,  A61M25/003 ,  A61M25/0043 ,  A61M25/008 ,  A61M2025/0034 ,  A61M2025/0037 ,  A61M2025/1056

摘要： The therapeutic catheter comprises a lumen communicating from the user's side end to the terminal tip part thereof, a main shaft having, at its tip, a guide wire lumen, a hub at its user's side end, and a slit in the guide wire lumen through its entire length, or the therapeutic catheter comprises a main shaft having a lumen communicating from the user's side end to the terminal tip part thereof, a guide wire shaft having, at its tip, a guide wire lumen, a hub at the user's side end of the main shaft, and a slit in the guide wire shaft through its entire length. The guide wire or the shaft of the other catheter playing the role of the guide wire can be rapidly disposed in the guide wire lumen through the slit.

摘要翻译： 治疗导管包括从使用者的侧端与其末端部分连通的内腔，主轴在其尖端处具有导丝管腔，在其使用者侧端部处的轮毂和在导丝管腔中的狭缝 其整个长度或治疗导管包括主轴，其具有从使用者的侧端连接到其末端部分的内腔;导丝轴，其尖端处具有导丝管腔，在使用者侧端部具有轮毂 的主轴，以及导丝线轴的整个长度上的狭缝。 作为引导线的作用的另一导管的引导线或轴可以通过狭缝快速地设置在导丝管腔中。

公开(公告)号：US07247147B2

公开(公告)日：2007-07-24

申请号：US10415997

申请日：2001-11-08

申请人： Takuji Nishide ,  Kohei Fukaya ,  Masato Hashiba

发明人： Takuji Nishide ,  Kohei Fukaya ,  Masato Hashiba

IPC分类号： A61M29/00

CPC分类号： A61M25/104 ,  A61M25/0045 ,  A61M25/0054

摘要： The medical balloon catheter of the present invention comprises a catheter shaft composed of a distal end shaft and a proximal end shaft and a balloon on the distal end of the distal end shaft, wherein the proximal end shaft is composed of a single member and the distal end portion of the proximal end shaft is lower in rigidity than the other parts thereof. The present invention also provides a medical balloon catheter having a structure in which a tube for passing a guidewire inside thereof is arranged so as to pass inside the balloon and the balloon and tube are fused together in the vicinity of the distal end of the catheter, wherein the ratio of the outer diameter of the small-diameter portion on the distal end side of the tube to the outer diameter of the proximal end portion is no less than 0.85.

摘要翻译： 本发明的医用气囊导管包括由前端轴和近端轴构成的导管轴和远端轴的远端上的气囊，其中，近端轴由单个构件和远端构成 近端轴的端部刚性低于其他部分。 本发明还提供一种医疗气囊导管，其具有将导线内部通过的管布置成在气囊内部通过的结构，并且气球和管在导管的远端附近熔合在一起， 其中，所述管的前端侧的小直径部的外径与所述基端部的外径之比为0.85以上。

公开(公告)号：US20120109058A1

公开(公告)日：2012-05-03

申请号：US13382893

申请日：2010-07-06

申请人： Kohei Fukaya

发明人： Kohei Fukaya

IPC分类号： A61M29/02

CPC分类号： A61F9/00772 ,  A61M25/02 ,  A61M25/09 ,  A61M2025/0293

摘要： Medical devices that are inserted into a body and that are used for treating a lumen inside a body sometimes use an insertion aid during insertion. However, there was a tendency for the relative positions of the insertion aid and the medical device to change, causing problems such as reduced operability and the insertion aid breaking the medical device during insertion. Disclosed are an insertion aid used by being placed within a medical device, and a medical device using said insertion aid. The insertion aid has a mechanism for holding said medical device from the inside, and said medical device uses said insertion aid, thereby making it possible to fix the relative positions of the insertion aid and the medical device when necessary.

摘要翻译： 插入体内并用于治疗体内腔的医疗装置有时在插入时使用插入辅助装置。 然而，插入辅助装置和医疗装置的相对位置存在变化的趋势，导致插入时使操作性降低和插入辅助装置破坏医疗装置等问题。 公开了通过放置在医疗装置内的插入辅助装置和使用所述插入辅助装置的医疗装置。 插入辅助装置具有用于从内部保持医疗装置的机构，并且所述医疗装置使用所述插入辅助装置，从而可以在需要时固定插入辅助装置和医疗装置的相对位置。

公开(公告)号：US20100057093A1

公开(公告)日：2010-03-04

申请号：US12526376

申请日：2008-02-07

申请人： Takeshi Ide ,  Kazuaki Yamamoto ,  Kohei Fukaya ,  Ryoji Nakano

发明人： Takeshi Ide ,  Kazuaki Yamamoto ,  Kohei Fukaya ,  Ryoji Nakano

IPC分类号： A61F9/00

CPC分类号： A61F2/1662 ,  A61B17/3468 ,  A61F2/148 ,  A61F9/0017 ,  A61F9/007

摘要： [PROBLEMS] To provide an injector for ophthalmology which can guide an implant easily to an transplant place without causing any damage to the implant when the implant is inserted into an eyeball. [MEANS FOR SOLVING PROBLEMS] The injector for an eye used for inserting an implant into an eyeball comprises an outer tube, and an implant holding structure arranged in the outer tube to be slidable with respect to the outer tube. The implant holding structure has an implant holding portion which can be contained in the outer tube and forms a space for containing the implant between the implant holding portion and the inner surface of the outer tube when it is contained in the outer tube. The implant holding portion projects from the outer tube when the implant holding structure is advanced and the implant can be taken out from the outer tube.

摘要翻译： [问题]提供一种用于眼科的注射器，其可以将植入物容易地引导到移植位置，而不会在将植入物插入眼球时对植入物造成任何损害。 用于解决问题的手段用于将植入物插入眼球的眼睛用注射器包括外管和布置在外管中以相对于外管滑动的植入物保持结构。 植入物保持结构具有植入物保持部分，该植入物保持部分可容纳在外管中并且当其被容纳在外管中时形成用于将植入物容纳在植入物保持部分和外管内表面之间的空间。 当植入物保持结构前进时，植入物保持部分从外管突出，并且植入物可以从外管中取出。

公开(公告)号：US20070250157A1

公开(公告)日：2007-10-25

申请号：US11574879

申请日：2005-09-01

申请人： Takuji Nishide ,  Yuki Takiguchi ,  Ryoji Nakano ,  Kohei Fukaya ,  Masaji Kawatsu

发明人： Takuji Nishide ,  Yuki Takiguchi ,  Ryoji Nakano ,  Kohei Fukaya ,  Masaji Kawatsu

IPC分类号： A61F2/06

CPC分类号： A61L31/148 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/9155 ,  A61F2210/0076 ,  A61F2230/0054 ,  A61F2250/0035 ,  A61F2250/0067 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/41 ,  A61L2300/416 ,  A61L2300/606 ,  A61L2300/608 ,  A61L2300/61

摘要： It is intended to easily provide a stent for placement in body which can hold an increased amount of a drug without causing cracking or peeling in the coating layer with the dilation of the stent and from which the drug can be sustainedly released as far as possible. Namely, a stent for placement in body having a coating layer mainly comprising a drug and a polymer in at least a part of the stent surface wherein the coating layer consists of an inner layer and an outer layer, the weight ratio of drug/polymer, which is defined based on the weights of the drug and the polymer contained in each layer, of the inner layer is higher than that of the outer layer, and the outer layer contains an efficacious amount of the drug.

摘要翻译： 旨在容易地提供用于放置在体内的支架，其能够容纳增加量的药物，而不会随着支架的扩张而在涂层中引起裂纹或剥离，并且药物可以尽可能地持续释放。 即，用于放置在本体中的支架，其具有主要包含药物的涂层和在支架表面的至少一部分中的聚合物，其中所述涂层由内层和外层组成，药物/聚合物的重量比， 内层中含有的药物重量和各层中所含的聚合物的含量高于外层，外层含有有效量的药物。

公开(公告)号：US20070038289A1

公开(公告)日：2007-02-15

申请号：US10563488

申请日：2004-07-23

申请人： Takuji Nishide ,  Ryoji Nakano ,  Shinya Yoshida ,  Kohei Fukaya ,  Masaji Kawatsu

发明人： Takuji Nishide ,  Ryoji Nakano ,  Shinya Yoshida ,  Kohei Fukaya ,  Masaji Kawatsu

IPC分类号： A61F2/90

CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/9155 ,  A61F2002/91558 ,  A61F2230/0054

摘要： As a treatment for angiostenosis, angioplasty (PTA or PTCA) of expanding a small-sized balloon in a vessel has been commonly conducted. However, this treatment easily causes repeated stenosis (restenosis) after the treatment. Placement of a stent in a vessel is also effective in decreasing restenosis, but this treatment may also cause restenosis. The present invention provides a stent containing a poly (lactide-co-glycolide) or both a poly (lactide-co-glycolide) and an immunosuppressive agent in at least a portion of a surface of the stent, and further containing a material nondegradable in vivo.

摘要翻译： 作为血管狭窄症的治疗方法，通常进行血管成形术（PTA或PTCA）扩大血管中的小型气球。 然而，这种治疗容易导致治疗后重复狭窄（再狭窄）。 支架置于血管中也有效减少再狭窄，但这种治疗也可能引起再狭窄。 本发明提供一种在支架表面的至少一部分中含有聚（丙交酯 - 共 - 乙交酯）或聚（丙交酯 - 共 - 乙交酯）和免疫抑制剂两者的支架，并且还含有不可降解的材料 体内。

公开(公告)号：US06960186B1

公开(公告)日：2005-11-01

申请号：US09980979

申请日：2000-05-11

申请人： Kohei Fukaya ,  Takuji Nishide ,  Ryoji Nakano ,  Hiromi Maeda ,  Shogo Miki

发明人： Kohei Fukaya ,  Takuji Nishide ,  Ryoji Nakano ,  Hiromi Maeda ,  Shogo Miki

IPC分类号： A61F2/958 ,  A61M25/00 ,  A61M29/02 ,  A61M31/00 ,  A61M37/00

CPC分类号： A61M25/1027 ,  A61M25/0045 ,  A61M25/0068 ,  A61M25/1002 ,  A61M25/1038 ,  A61M25/104 ,  A61M2025/0004 ,  A61M2025/0183 ,  A61M2025/1056 ,  A61M2025/1093

摘要： The present invention is a balloon catheter used primarily in treatment and surgery for the purpose of dilating lesion sites such as strictures or blockages in passages in the human body. The balloon catheter of the present invention has a structure wherein a guide wire passing tubular member is deployed passing through the interior of the expansion body, and the outer surface of the tubular member and the expansion body are concentrically fused near the distal end of the catheter. This is a balloon catheter that is characterized by the fact that the Shore hardness of the material configuring the outermost surface of the tubular member is smaller than the Shore hardness of the material configuring the expansion body. It is therefore possible to flexibly adjust the tip portion formed by securing the expansion body and the guide wire passing tubular member.

摘要翻译： 本发明是一种主要用于治疗和手术的气囊导管，用于在人体的通道中扩张病变部位如狭窄或阻塞。 本发明的气囊导管具有通过管状构件的导丝管穿过膨胀体内部的结构，并且管状构件和膨胀体的外表面在导管的远端附近同心地熔合 。 这是一种球囊导管，其特征在于，构成管状构件的最外表面的材料的肖氏硬度小于构成膨胀体的材料的肖氏硬度。 因此，可以灵活地调节通过固定膨胀体和导丝通过管状构件形成的尖端部分。

公开(公告)号：US06706010B1

公开(公告)日：2004-03-16

申请号：US09529081

申请日：2000-04-07

申请人： Shogo Miki ,  Kohei Fukaya ,  Takuji Nishide ,  Masato Hashiba ,  Ryoji Nakano ,  Hiromi Maeda

发明人： Shogo Miki ,  Kohei Fukaya ,  Takuji Nishide ,  Masato Hashiba ,  Ryoji Nakano ,  Hiromi Maeda

IPC分类号： A61M300

CPC分类号： A61M25/1034 ,  A61M25/0054 ,  A61M25/1036 ,  A61M25/1038 ,  A61M2025/1061 ,  A61M2025/1093

摘要： It is an object of the present invention to provide a balloon catheter in which the inner tube is prevented from slackening after balloon inflation, improving the rewrapping of the balloon, discontinuity in the rigidity of the joined portions of the outer tube and the balloon is lessened, which prevents breakage, and the catheter advances through blood vessels better and passes more easily through narrow segments, preventing the catheter from “accordioning” and enhancing insertion force transmission. The balloon catheter pertaining to the present invention has a catheter shaft (1) with a double-tube structure comprising an outer tube (4) and an inner tube (5), and a balloon (3) disposed at the distal end portion of this catheter shaft (1). A guide tube (11) having an outside diameter smaller than the inside diameter of the outer tube (4) and having an inside diameter larger than the outside diameter of the inner tube (5) is disposed at least at the distal end portion of the outer tube (4) so as to form a double-tube with the outer tube (4), and the inner tube (5) is not fixed, but passes through the interior of the guide tube (11) in the axial direction.

摘要翻译： 本发明的目的是提供一种球囊导管，其中防止内囊在球囊膨胀后松弛，改善球囊的重新包裹，外管和球囊的接合部分的刚度不连续性减小 防止断裂，并且导管更好地前进通过血管，并且更容易地通过狭窄的区段，防止导管“手风琴”并增强插入力传递。 本发明的气囊导管具有导管轴（1），其具有包括外管（4）和内管（5）的双管结构，以及设置在该管的前端部的气囊（3） 导管轴（1）。 具有比外管（4）的内径小的内径比内管（5）的外径大的外径的导管（11）至少设置在内管 外管（4）形成与外管（4）的双管，内管（5）不固定，但沿轴向通过导管（11）的内部。