公开(公告)号：US06638242B2

公开(公告)日：2003-10-28

申请号：US10086033

申请日：2002-02-28

申请人： Jon S. Wilson ,  Carl M. Fleming ,  Kenneth T. Cassidy ,  Ronald D. Boyd ,  Gary S. Fleming

发明人： Jon S. Wilson ,  Carl M. Fleming ,  Kenneth T. Cassidy ,  Ronald D. Boyd ,  Gary S. Fleming

IPC分类号： A61M300

CPC分类号： A61M25/0029 ,  A61M1/16 ,  A61M1/3653 ,  A61M1/3659 ,  A61M25/0028 ,  A61M25/0097 ,  A61M2025/0031 ,  A61M2025/0034 ,  A61M2025/0037 ,  A61M2025/0098

摘要： A method of inserting a multi-lumen catheter assembly. First, an incision is made near the area to be catheterized. The proximal portion of the multi-lumen catheter tube is then inserted into the area to be catheterized. A subcutaneous tunnel is created, and the first end of the tunnel is near the incision. The catheter tube is then routed through the subcutaneous tunnel and pulled tube through a second end of the subcutaneous tunnel. The hub body is then securely attached to the catheter tube by connecting the connection cover to the hub body by threaded engagement. In a preferred embodiment the hub body is attached to the catheter tube by backfitting the connection cover over the catheter tube. A compression sleeve is also backfit over the catheter tube. The cannulae of the hub body are inserted into the lumens of the catheter tube to create fluid communication therebetween. The connection between the cannulae and the first and the catheter tube is compressed by sliding the compression sleeve over the cannulae that have been inserted into the catheter tube.

公开(公告)号：US06592544B1

公开(公告)日：2003-07-15

申请号：US09450032

申请日：1999-11-24

申请人： Charles R. Mooney ,  Clifford E. Currier

发明人： Charles R. Mooney ,  Clifford E. Currier

IPC分类号： A61M300

CPC分类号： A61M39/24 ,  A61M39/0693 ,  A61M2039/242 ,  A61M2039/2433

摘要： A vascular access device is provided that has a device lumen valve and a safety valve feature to prevent leakage of blood from a lumen of such device. The vascular access device includes a sheath which may have an outer tube and structure defining a device lumen located therein. The access device further includes a detachable device valve which provides sealing of the device lumen. In addition, a non-detachable hemostasis safety valve is provided on the proximal end of the device lumen to seal the device lumen when no device valve is present. The device valve attaches to and simultaneously opens the proximal end of the hemostasis safety valve. In one embodiment, the device valve includes a distal projection that pierces an elastomeric valve member of the hemostasis safety valve. The elastomeric valve member of the hemostasis safety valve is stiffer than an elastomeric valve member of the device valve, and prevents introduction of guidewires and highly flexible catheters therethrough.

摘要翻译： 提供一种血管通路装置，其具有装置内腔阀和安全阀特征，以防止血液从该装置的内腔泄漏。 血管进入装置包括护套，护套可以具有限定位于其中的装置内腔的外管和结构。 进入装置还包括提供装置内腔的密封的可拆卸装置阀。 此外，在不存在装置阀的情况下，在装置内腔的近端设置有不可拆卸的止血安全阀，以密封装置内腔。 装置阀连接并同时打开止血安全阀的近端。 在一个实施例中，装置阀包括穿透止血安全阀的弹性阀构件的远端突出部。 止血安全阀的弹性体阀构件比装置阀的弹性阀构件更硬，并且防止引导线和高柔性导管穿过其中。

公开(公告)号：US06409700B1

公开(公告)日：2002-06-25

申请号：US09273571

申请日：1999-03-22

申请人： John M. Siegel, Jr. ,  Vinod B. Makhijani ,  Ming Lei ,  Jagannath Raghavan

发明人： John M. Siegel, Jr. ,  Vinod B. Makhijani ,  Ming Lei ,  Jagannath Raghavan

IPC分类号： A61M300

CPC分类号： A61M1/3653 ,  A61M1/3658 ,  A61M1/3659 ,  A61M1/3661 ,  A61M25/0021 ,  A61M25/003 ,  A61M2025/0031 ,  A61M2025/0037 ,  A61M2025/0073

摘要： Blood is withdrawn from a vein by a double lumen catheter that has an elongated tube with unitary outer walls. A longitudinal planar septum divides the interior of the tube into an inlet lumen and a longer return lumen. The inlet lumen extends from a proximal end of the tube to an end terminating in a distally forward facing aperture. The return lumen extends contiguously with the inlet lumen from the proximal end of the tube to an end terminating in a distally forward facing aperture spaced in the longitudinal direction distally forward of the inlet lumen aperture. A diverting structure extends from an outer wall of the return lumen distally forward of the aperture of the inlet lumen. The diverting structure diverts flow of treated fluid discharged from the return lumen away from the distally forward facing aperture of the inlet lumen. The blood withdrawn via the catheter is circulated for treatment in a blood purification system.

摘要翻译： 血液通过具有整体外壁的细长管的双腔导管从静脉中取出。 纵向平面隔膜将管的内部分成入口腔和更长的回流腔。 入口腔从管的近端延伸到终止于向前的朝前的孔的端部。 返回内腔与入口腔从管的近端连续延伸到终端于远端前进对面的端部的端部，其沿纵向方向向前远离入口腔孔的前方延伸。 转向结构从返回腔的外壁延伸到入口腔的孔的远侧前方。 转向结构将从返回腔排出的经处理流体的流动远离入口腔的远端向前的孔。 通过导管取出的血液循环用于血液净化系统中的治疗。

公开(公告)号：US06371935B1

公开(公告)日：2002-04-16

申请号：US09378676

申请日：1999-08-20

申请人： John A. Macoviak ,  Wilfred J. Samson

发明人： John A. Macoviak ,  Wilfred J. Samson

IPC分类号： A61M300

CPC分类号： A61M25/0067 ,  A61B17/12036 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12131 ,  A61B17/12136 ,  A61B2017/1205 ,  A61M25/007 ,  A61M25/1002 ,  A61M2025/0037 ,  A61M2025/0073 ,  A61M2025/1072 ,  A61M2025/1095

摘要： The invention is a catheter with a fluid flow divider positioned near the distal end of the catheter for dividing a first lumen into two channels at a point where a second lumen branches from the first lumen, and for selectively perfusing the branch lumen. The invention is particularly suited for use in the aortic arch. The fluid flow divider may comprise one or more inflatable chambers or one or more deployable shrouds comprising a plurality of arms with a webbing extending between adjacent arms. The inflatable chambers may be relatively noncompliant or they may be compliant, exhibiting elastic behavior after initial inflation, to closely fit the aortic lumen size and curvature. The catheter may further include one or more additional or auxiliary flow control members located upstream or downstream from the fluid flop divider to further segment the patient's circulatory system for selective perfusion to different organ systems within the body or to assist in anchoring the catheter in a desired position.

摘要翻译： 本发明是一种导管，其具有定位在导管远端附近的流体分流器，用于在第二腔从第一腔分支的点处将第一腔分成两个通道，并用于选择性地灌注分支腔。 本发明特别适用于主动脉弓。 流体分流器可以包括一个或多个可充气室或一个或多个可展开的护罩，其包括具有在相邻臂之间延伸的织带的多个臂。 充气室可以是相对不符合的，或者它们可以是柔顺的，在初始充气之后表现出弹性，以紧密地适应主动脉腔的尺寸和曲率。 导管还可以包括一个或多个位于流体翻转分隔器的上游或下游的附加或辅助流动控制构件，以进一步分割患者的循环系统以选择性灌注到体内不同的器官系统，或帮助将导管锚定在期望的 位置。

公开(公告)号：US06702776B2

公开(公告)日：2004-03-09

申请号：US09759582

申请日：2001-01-11

申请人： David G. Quinn

发明人： David G. Quinn

IPC分类号： A61M300

CPC分类号： A61M25/0069 ,  A61M25/007 ,  A61M2025/0081

摘要： A catheter including a catheter tube and a bolus tip, the bolus having a radially extending main side port. In one embodiment the catheter also has second and third side ports axially spaced from said main side port. The second and third side ports are each axially elongated, with an edge which is semi-circular in cross-section. The second side port is displaced 180° from the main side port. The third side port is axially aligned with the main port. The catheter is thickened in a dimple opposite each of the second and third side ports. Another catheter embodiment specifically for hemodialysis includes a dual lumen tube with a bolus at its distal end. A main venous port is formed in one side of the bolus adjacent the bullet nose of the bolus. Variations of this embodiment utilize a bolus with a 13.5 French tube connector section and a 10 French nose section, with the venous port formed in the nose section.

摘要翻译： 包括导管和推注头的导管，所述推注具有径向延伸的主侧端口。 在一个实施例中，导管还具有与所述主侧端口轴向间隔开的第二和第三侧端口。 第二和第三侧端口各自轴向延伸，其边缘是横截面为半圆形。 第二侧端口从主侧端口移位180°。 第三侧端口与主端口轴向对准。 导管在与第二和第三侧端口相对的凹坑中加厚。 专门用于血液透析的另一导管实施例包括在其远端具有推注的双腔管。 主要静脉口形成在推注的一侧，与推注的子弹鼻子相邻。 该实施例的变化使用具有13.5法国管连接器部分和10法国鼻部的推注，其中在鼻部形成静脉端口。

公开(公告)号：US06656106B2

公开(公告)日：2003-12-02

申请号：US09930904

申请日：2001-08-17

申请人： Bruno Schmidt

发明人： Bruno Schmidt

IPC分类号： A61M300

CPC分类号： A61M37/0069 ,  A61N5/1027 ,  A61N2005/1011

摘要： An apparatus and method for visually verifying the quantity of seeds and spacers in a brachytherapy needle. In a first embodiment, the needle is pointed upwardly and seeds and spacers slide from a lumen of the needle, under the influence of gravity, into the lumen of a clear tube that is positioned in axial alignment with the lumen of the needle by a hub. In a second embodiment, the needle is received within the lumen of the clear tube and a stylet is used to push a string of bone wax, seeds, and spacers from the lumen of the needle into the lumen of the clear tube for visual verification. A plunger rod is introduced into the proximal end of the clear tube to push the string back into the needle and the clear tube and plunger are removed to enable use of the needle. In both embodiments, the plunger rod is fully inserted into the clear tube during shipment to prevent unwanted displacement of the seeds and spacers from the needle.

摘要翻译： 用于视觉验证近距离放射治疗针中的种子和间隔物的量的装置和方法。 在第一实施例中，针向上指向，并且种子和间隔物在重力的影响下从针的内腔滑动到透明管的内腔中，该透明管的定位成与针的内腔轴向对准， 。 在第二实施例中，针被容纳在透明管的内腔内，并且使用探针将一根骨蜡，种子和间隔物串从针管的内部推到透明管的内腔中，以进行目视验证。 柱塞杆被引入到透明管的近端中以将线推回到针中，并且去除透明管和柱塞以使得能够使用针。 在两个实施例中，柱塞杆在运输期间完​​全插入透明管中，以防止种子和间隔物从针中不期望的移位。

公开(公告)号：US06635029B1

公开(公告)日：2003-10-21

申请号：US09311498

申请日：1999-05-13

申请人： Andrea Venturelli

发明人： Andrea Venturelli

IPC分类号： A61M300

CPC分类号： A61M25/104 ,  A61M25/0662 ,  A61M2025/1056

摘要： A dilation catheter structure of the rapid exchange is provided with an inflatable balloon and with a lumen for a guide thread. The catheter comprises a distal tube (12) and a guide tube (13). The guide tube (13) extends into the distal tube (12), and the proximal ends (13′, 12′) of the guide tube (13) and the distal tube (12) are joined to one another and at the distal end (11′) of the main tube (11). The proximal end (13′) of the guide tube (13) has an opening on one side of the main tube (11) and the proximal end (12′) of the distal tube (12) reaches the distal end of the main tube and the proximal end of the guide tube tightly and simultaneously.

摘要翻译： 快速交换的扩张导管结构设置有可膨胀气囊和用于引导线的内腔。 导管包括远端管（12）和导管（13）。 引导管（13）延伸到远端管（12）中，并且导管（13）和远端管（12）的近端（13'，12'）彼此接合并且在远端 （11）的（11'）。 导管（13）的近端（13'）在主管（11）的一侧具有开口，远端管（12）的近端（12'）到达主管 并且引导管的近端紧密并同时。

公开(公告)号：US06540714B1

公开(公告)日：2003-04-01

申请号：US09651455

申请日：2000-08-30

申请人： David G. Quinn

发明人： David G. Quinn

IPC分类号： A61M300

CPC分类号： A61M25/0069 ,  A61M25/007 ,  A61M2025/0081

摘要： A hemodialysis catheter including a catheter tube and a bolus tip, the bolus having a radially extending main side port. The catheter also has second and third side ports axially spaced from said main side port. The second and third side ports are each axially elongated, with an edge which is semi-circular in cross-section. The second side port is displaced 180° from the main side port. The third side port is axially aligned with the main port. The catheter is thickened in an arch opposite each of the second and third side ports.

摘要翻译： 一种血液透析导管，其包括导管和推注头，所述推注具有径向延伸的主侧端口。 导管还具有与所述主侧端口轴向间隔开的第二和第三侧端口。 第二和第三侧端口各自轴向延伸，其边缘是横截面为半圆形。 第二侧端口从主侧端口移位180°。 第三侧端口与主端口轴向对准。 导管在与第二和第三侧端口相对的拱中增厚。

公开(公告)号：US06402726B1

公开(公告)日：2002-06-11

申请号：US09810356

申请日：2001-03-19

申请人： Joseph N. Genese

发明人： Joseph N. Genese

IPC分类号： A61M300

CPC分类号： A61M25/0113 ,  A61M25/002 ,  A61M2210/1089

摘要： A catheter movement control device is presented having therein a resilient biasing member and a tube gripper which mount on a catheter tube. The biasing member and tube gripper are contained within a housing having a shoulder proximate the catheter tube. As the catheter tube is free to move in a forward direction through the housing, upon attempted rearward movement the biasing member engages the tube gripper causing it to pivot against a shoulder within the housing. Upon pivoting the tube gripper tightly engages the catheter tube preventing any further rearward movement of the catheter tube.

摘要翻译： 呈现导管运动控制装置，其中具有安装在导管上的弹性偏置构件和管夹持器。 偏压构件和管夹持器容纳在具有靠近导管管的肩部的壳体内。 当导管在向前的方向上自由地移动通过壳体时，当试图向后移动时，偏置构件接合管夹持器，使得其相对于壳体内的肩部枢转。 当枢转时，管夹紧器紧紧地接合导管管，防止导管的任何进一步向后运动。

公开(公告)号：US06758828B2

公开(公告)日：2004-07-06

申请号：US10013636

申请日：2001-12-10

申请人： Bruce E. Hammer ,  Mark J. Conroy

发明人： Bruce E. Hammer ,  Mark J. Conroy

IPC分类号： A61M300

CPC分类号： A61M1/1678 ,  A61B2017/00969 ,  A61K35/00 ,  A61M25/00

摘要： An apparatus delivers an agent to a treatment region, the apparatus having an outer cannula or lumen that has an internal surface and an external surface, the external surface being substantially smooth to penetrate tissue whereas the distal end is tapered; an inner cannula, or lumen coaxial to the outer cannula, providing a common fluid path (that is the same fluid passes through both the inner cannula and outer cannula) at the distal end with the inner surface of the outer cannula; a source of fluid to be passed through the common fluid path, the source of fluid comprising at least a reservoir of nutrients and/or gases for maintaining cells contained in a lumen coaxial and internal to the inner cannula; a semipermeable membrane comprises the surface of the lumen, thus allowing controlled material transport across the lumen surface; a source of cells or other biologically active material mass flow connected to the proximal lumen so that the cells or other biologically active material can exit the distal portion upon entering the target tissue; and a first flow distributor located at the proximal end of the outer cannula to provide substantially uniform flow through the outer cannula.

摘要翻译： 一种装置将药剂递送到治疗区域，所述装置具有外套管或内腔，其具有内表面和外表面，所述外表面基本上平滑以穿透组织，而远端是锥形的; 与外套管同轴的内插管或腔，在远端处提供与外插管的内表面相同的共同流体路径（即相同的流体穿过内插管和外套管）; 要流过公共流体路径的流体源，流体源包括营养物和/或气体的至少一个储存器，用于维持包含在内套管同轴和内部的内腔中的细胞; 半透膜包括内腔的表面，从而允许受控的材料在管腔表面上的输送; 连接到近端内腔的细胞源或其他生物活性物质质量流，使得细胞或其他生物活性物质在进入靶组织时可以离开远侧部分; 以及位于外套管的近端处的第一流量分配器，以提供穿过外套管的基本上均匀的流动。