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1.
公开(公告)号:US20130011485A1
公开(公告)日:2013-01-10
申请号:US13177034
申请日:2011-07-06
申请人: Mu-Yi HUA , Hung-Wei Yang , Cheng-Keng Chuang , See-Tong Pang , Hao-Li Liu , Rung-Ywan Tsai , Kun-Lung Chuang
发明人: Mu-Yi HUA , Hung-Wei Yang , Cheng-Keng Chuang , See-Tong Pang , Hao-Li Liu , Rung-Ywan Tsai , Kun-Lung Chuang
IPC分类号: A61K9/50 , A61P35/00 , A61K31/785 , B82Y5/00
CPC分类号: A61K47/48861 , A61K9/5094 , A61K31/337 , A61K47/6923 , B82Y5/00 , Y10S977/773 , Y10S977/788 , Y10S977/906
摘要: The present invention discloses a magnetic nanomedicine for inhibiting/treating human prostate cancer, which comprises a core containing a magnetic particle having a diameter of less than 10 nm; a shell made of a carboxylated polyaniline and encapsulating the core; and a medicine covalently linked to the shell and able to inhibit/treat prostate cancer. The magnetic nanomedicine of the present invention not only has superior thermal stability and but also has water solubility higher than that of the conventional anti-prostate cancer medicine. Further, the magnetic nanomedicine of the present invention can be magnetically conducted to the cancer area to increase the local concentration of medicine and enhance the therapeutic effect.
摘要翻译: 本发明公开了一种用于抑制/治疗人前列腺癌的磁性纳米医药,其包含含有直径小于10nm的磁性颗粒的核心; 由羧基化聚苯胺制成的壳,并封装核心; 和与壳共价连接并能够抑制/治疗前列腺癌的药物。 本发明的磁性纳米医药不仅具有优异的热稳定性,而且还具有比常规抗前列腺癌药物更高的水溶性。 此外,本发明的磁性纳米医药可以磁性地导入癌症区域,以增加药物的局部浓度,增强治疗效果。
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2.
公开(公告)号:US5414024A
公开(公告)日:1995-05-09
申请号:US321803
申请日:1994-10-12
申请人: Shin-Chuan Yao , Jong-Fu Wu , Kun-Lin Cheng , Chiu-Hsiung Tsai , Farn-Ping Koong , Kun-Lung Chuang , Shu-Lan Yao , Chin-Liu Liu
发明人: Shin-Chuan Yao , Jong-Fu Wu , Kun-Lin Cheng , Chiu-Hsiung Tsai , Farn-Ping Koong , Kun-Lung Chuang , Shu-Lan Yao , Chin-Liu Liu
CPC分类号: D06N3/14 , D06N3/0059 , D06N3/0063 , Y10S428/921 , Y10S521/906 , Y10T428/249982 , Y10T428/249987 , Y10T442/2139 , Y10T442/2713
摘要: A water-permeable and fire-resistant product and the preparing method thereof is disclosed. The water-permeable and fire-resistant product is made of a fabric layer and a purous film adhered thereon. The porous film of this invention comprises polyurethane resin; a first fire-resistant agent; a second fire-resistant agent, an inorganic fire-resistant agent and an additive agent. The first fire-resistant agent used is selected from the group consisting of paraffine chlorinated, decabromodiphenyl oxide, hexachloro benzene, hexabromo benzene, pentabromo ethyl benzene, pentabromo diphenyl oxide and octabromo diphenyl ether. The second fire-resistant agent used is selected from the group consisting of Sb2O3 and Sb2O5. The surface of the product produced is smooth.
摘要翻译: 公开了一种透水耐火制品及其制备方法。 透水防火产品由粘合在其上的织物层和薄膜制成。 本发明的多孔膜包含聚氨酯树脂; 第一种耐火剂; 第二耐火剂,无机防火剂和添加剂。 所用的第一种耐火剂选自氯化,十溴二苯醚,六氯苯,六溴苯,五溴乙苯,五溴二苯氧化物和八溴二苯醚等组成的组。 所用的第二种耐火剂选自Sb2O3和Sb2O5。 所生产的产品的表面光滑。
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公开(公告)号:US20080188152A1
公开(公告)日:2008-08-07
申请号:US11876782
申请日:2007-10-23
IPC分类号: B32B5/02
CPC分类号: B32B27/12 , D06M11/155 , D06M11/47 , D06M15/564 , D06M23/08 , D06N3/0056 , D06N3/183 , D06N7/0092 , D06N2201/02 , D06N2201/0254 , D06N2201/0263 , D06N2201/042 , D06N2201/06 , D06N2203/041 , D06N2203/061 , D06N2203/068 , D06N2205/10 , D06N2209/123 , D06N2209/128 , D06N2209/141 , Y10T428/2933 , Y10T442/2139 , Y10T442/2148 , Y10T442/2164 , Y10T442/2861 , Y10T442/2869
摘要: A moisture-vapor-permeable and water-resistant fiber involves a layer of base fabric, a moisture-vapor-permeable layer, and a water absorption layer. The moisture vapor permeable layer is obtained by coating or laminating the inner side of the fabric with a moisture-vapor-permeable resin, which prohibits the penetration of the water droplets but allows the penetration of the moisture vapor molecules. The moisture absorption layer with intricate and colorful design is composed of binding resin blended with fiber powder and/or inorganic powder, and which is dot-coated or dot-printed onto the inner side of the moisture-vapor-permeable and water-resistant layer. The fiber powder or inorganic powder is highly hydrophilic and highly absorbent in its moisture absorption ability, which, when the clothes are fabricated, can prevent the penetration of raindrops but allows the transmission of the evaporated vapor of sweat through the fabric. Moreover, it is capable of absorbing plentiful amount of sweat.
摘要翻译: 透湿防水纤维包括底层织物,透湿层和吸水层。 水蒸气透过层是通过用透湿水分的树脂涂布或层压织物的内侧而获得的,其阻止水滴的渗透,但允许湿气分子的渗透。 具有复杂多彩设计的吸湿层由与纤维粉末和/或无机粉末混合的粘合树脂组成,并且在水分透湿防水层的内侧点涂或点印 。 纤维粉末或无机粉末具有高亲水性和吸湿性,其吸湿能力强,当制造衣物时,可以防止雨滴渗透,但可以使汗液蒸发蒸气透过织物。 而且,它能够吸收大量的汗水。
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公开(公告)号:US20120328705A1
公开(公告)日:2012-12-27
申请号:US13166450
申请日:2011-06-22
申请人: Mu-Yi Hua , Hong-Wei Yang , Cheng-Keng Chuang , See-Tong Pang , Rung-Ywan Tsai , Kun-Lung Chuang
发明人: Mu-Yi Hua , Hong-Wei Yang , Cheng-Keng Chuang , See-Tong Pang , Rung-Ywan Tsai , Kun-Lung Chuang
IPC分类号: A61K9/51 , A61P35/00 , A61K31/704 , B82Y5/00
CPC分类号: A61K31/704 , A61K9/0009
摘要: A magnetic nanomedicine for tumor suppression and therapy, comprising: a core, made of magnetic nanoparticles; a shell, encapsulating said core and is made of carboxylated polyaniline (SPAnH); and a tumor suppression medicine Epirubicin (EPI) or Doxorubicin (DOX) covalently bonded onto said shell. Said magnetic nanomedicine is capable of improving its thermal stability, and it can be dissolved uniformly in water, plus its superparamagnetic property, thus it can be guided by an outside magnetic field to concentrate to the site of tumor distribution to increase the local medicine concentration and enhance therapy effect.
摘要翻译: 一种用于肿瘤抑制和治疗的磁性纳米医药,包括:由磁性纳米颗粒制成的核心; 壳,封装所述芯并由羧化聚苯胺(SPAnH)制成; 以及共价键合到所述壳上的肿瘤抑制药物表柔比星(EPI)或多柔比星(DOX)。 所述磁性纳米医药能够提高其热稳定性,可以均匀地溶解在水中,加上其超顺磁性,可以通过外界磁场引导,集中到肿瘤分布部位,增加局部药物浓度, 增强疗效。
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5.
公开(公告)号:US5424350A
公开(公告)日:1995-06-13
申请号:US352743
申请日:1994-12-02
申请人: Shin-Chuan Yao , Jong-Fu Wu , Kun-Lin Cheng , Chiu-Hsiung Tsai , Farn-Ping Koong , Kun-Lung Chuang , Shu-Lan Yao , Chin-Liu Liu
发明人: Shin-Chuan Yao , Jong-Fu Wu , Kun-Lin Cheng , Chiu-Hsiung Tsai , Farn-Ping Koong , Kun-Lung Chuang , Shu-Lan Yao , Chin-Liu Liu
IPC分类号: C09D5/18 , C09D175/04 , C09K21/14 , C08K3/10 , C08K5/06
CPC分类号: C09K21/14 , C09D175/04 , C09D5/18 , Y10S521/906
摘要: A water-permeable and fire-resistant film and the preparing method thereof is disclosed. The water-permeable and fire-resistant film comprises polyurethane resin; a first fire-resistant agent; a second fire-resistant agent, an inorganic fire-resistant agent and an additive agent. The first fire-resistant agent used is selected from the group consisting of paraffine chlorinated, decabromodiphenyI oxide, hexachloro benzene, hexabromo benzene, pentabromo ethyl benzene, pentabromo diphenyl oxide and octabromo diphenyl ether. The second fire-resistant agent used is selected from the group consisting of Sb2O3 and Sb2OS. The surface of the film produced is smooth.
摘要翻译: 公开了一种透水耐火薄膜及其制备方法。 透水耐火膜包括聚氨酯树脂; 第一种耐火剂; 第二耐火剂,无机防火剂和添加剂。 所用的第一种耐火剂选自氯化,十溴二苯氧基,六氯苯,六溴苯,五溴乙苯,五溴二苯氧基和八溴二苯醚。 所用的第二种耐火剂选自Sb2O3和Sb2OS。 所生产的薄膜表面光滑。
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6.
公开(公告)号:US08889192B2
公开(公告)日:2014-11-18
申请号:US13177034
申请日:2011-07-06
申请人: Mu-Yi Hua , Hung-Wei Yang , Cheng-Keng Chuang , See-Tong Pang , Hao-Li Liu , Rung-Ywan Tsai , Kun-Lung Chuang
发明人: Mu-Yi Hua , Hung-Wei Yang , Cheng-Keng Chuang , See-Tong Pang , Hao-Li Liu , Rung-Ywan Tsai , Kun-Lung Chuang
CPC分类号: A61K47/48861 , A61K9/5094 , A61K31/337 , A61K47/6923 , B82Y5/00 , Y10S977/773 , Y10S977/788 , Y10S977/906
摘要: The present invention discloses a magnetic nanomedicine for inhibiting/treating human prostate cancer, which comprises a core containing a magnetic particle having a diameter of less than 10 nm; a shell made of a carboxylated polyaniline and encapsulating the core; and a medicine covalently linked to the shell and able to inhibit/treat prostate cancer. The magnetic nanomedicine of the present invention not only has superior thermal stability and but also has water solubility higher than that of the conventional anti-prostate cancer medicine. Further, the magnetic nanomedicine of the present invention can be magnetically conducted to the cancer area to increase the local concentration of medicine and enhance the therapeutic effect.
摘要翻译: 本发明公开了一种用于抑制/治疗人前列腺癌的磁性纳米医药,其包含含有直径小于10nm的磁性颗粒的核心; 由羧基化聚苯胺制成的壳,并封装核心; 和与壳共价连接并能够抑制/治疗前列腺癌的药物。 本发明的磁性纳米医药不仅具有优异的热稳定性,而且还具有比常规抗前列腺癌药物更高的水溶性。 此外,本发明的磁性纳米医药可以磁性地导入癌症区域,以增加药物的局部浓度,增强治疗效果。
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公开(公告)号:US08329222B1
公开(公告)日:2012-12-11
申请号:US13166450
申请日:2011-06-22
申请人: Mu-Yi Hua , Hong-Wei Yang , Cheng-Keng Chuang , See-Tong Pang , Rung-Ywan Tsai , Kun-Lung Chuang
发明人: Mu-Yi Hua , Hong-Wei Yang , Cheng-Keng Chuang , See-Tong Pang , Rung-Ywan Tsai , Kun-Lung Chuang
CPC分类号: A61K31/704 , A61K9/0009
摘要: A magnetic nanomedicine for tumor suppression and therapy, comprising: a core, made of magnetic nanoparticles; a shell, encapsulating said core and is made of carboxylated polyaniline (SPAnH); and a tumor suppression medicine Epirubicin (EPI) or Doxorubicin (DOX) covalently bonded onto said shell. Said magnetic nanomedicine is capable of improving its thermal stability, and it can be dissolved uniformly in water, plus its superparamagnetic property, thus it can be guided by an outside magnetic field to concentrate to the site of tumor distribution to increase the local medicine concentration and enhance therapy effect.
摘要翻译: 一种用于肿瘤抑制和治疗的磁性纳米医药,包括:由磁性纳米颗粒制成的核心; 壳,封装所述芯并由羧化聚苯胺(SPAnH)制成; 以及共价键合到所述壳上的肿瘤抑制药物表柔比星(EPI)或多柔比星(DOX)。 所述磁性纳米医药能够提高其热稳定性,可以均匀地溶解在水中,加上其超顺磁性,可以通过外界磁场引导,集中到肿瘤分布部位,增加局部药物浓度, 增强疗效。
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8.
公开(公告)号:US5393569A
公开(公告)日:1995-02-28
申请号:US195039
申请日:1994-02-14
申请人: Shin-Chuan Yao , Jong-Fu Wu , Kun-Lin Cheng , Chiu-Hsiung Tsai , Farn-Ping Koong , Kun-Lung Chuang , Shu-Lan Yao , Chin-Liu Liu
发明人: Shin-Chuan Yao , Jong-Fu Wu , Kun-Lin Cheng , Chiu-Hsiung Tsai , Farn-Ping Koong , Kun-Lung Chuang , Shu-Lan Yao , Chin-Liu Liu
IPC分类号: C09D5/18 , C09D175/04 , C09K21/14 , B05D3/02
CPC分类号: C09K21/14 , C09D175/04 , C09D5/18 , Y10S521/906
摘要: A water-permeable and fire-resistant film and the preparing method thereof is disclosed. The water-permeable and fire-resistant film comprises polyurethane resin; a first fire-resistant agent; a second fire-resistant agent, an inorganic fire-resistant agent and an additive agent. The first fire-resistant agent used is selected from the group consisting of paraffine chlorinated, decabromodiphenyl oxide, hexachloro benzene, hexabromo benzene, pentabromo ethyl benzene, pentabromo diphenyl oxide and octabromo diphenyl ether. The second fire-resistant agent used is selected from the group consisting of Sb203 and Sb205. The surface of the film produced is smooth.
摘要翻译: 公开了一种透水耐火薄膜及其制备方法。 透水耐火膜包括聚氨酯树脂; 第一种耐火剂; 第二耐火剂,无机防火剂和添加剂。 所用的第一种耐火剂选自氯化,十溴二苯醚,六氯苯,六溴苯,五溴乙苯,五溴二苯氧化物和八溴二苯醚等组成的组。 所使用的第二种耐火剂选自Sb 2 O 3和Sb 2 O 5。 所生产的薄膜表面光滑。
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公开(公告)号:US08247334B2
公开(公告)日:2012-08-21
申请号:US11876782
申请日:2007-10-23
CPC分类号: B32B27/12 , D06M11/155 , D06M11/47 , D06M15/564 , D06M23/08 , D06N3/0056 , D06N3/183 , D06N7/0092 , D06N2201/02 , D06N2201/0254 , D06N2201/0263 , D06N2201/042 , D06N2201/06 , D06N2203/041 , D06N2203/061 , D06N2203/068 , D06N2205/10 , D06N2209/123 , D06N2209/128 , D06N2209/141 , Y10T428/2933 , Y10T442/2139 , Y10T442/2148 , Y10T442/2164 , Y10T442/2861 , Y10T442/2869
摘要: A moisture-vapor-permeable and water-resistant fiber involves a layer of base fabric, a moisture-vapor-permeable layer, and a water absorption layer. The moisture vapor permeable layer is obtained by coating or laminating the inner side of the fabric with a moisture-vapor-permeable resin, which prohibits the penetration of the water droplets but allows the penetration of the moisture vapor molecules. The moisture absorption layer with intricate and colorful design is composed of binding resin blended with fiber powder and/or inorganic powder, and which is dot-coated or dot-printed onto the inner side of the moisture-vapor-permeable and water-resistant layer. The fiber powder or inorganic powder is highly hydrophilic and highly absorbent in its moisture absorption ability, which, when the clothes are fabricated, can prevent the penetration of raindrops but allows the transmission of the evaporated vapor of sweat through the fabric. Moreover, it is capable of absorbing plentiful amount of sweat.
摘要翻译: 透湿防水纤维包括底层织物,透湿层和吸水层。 水蒸气透过层是通过用透湿水分的树脂涂布或层压织物的内侧而获得的,其阻止水滴的渗透,但允许湿气分子的渗透。 具有复杂多彩设计的吸湿层由与纤维粉末和/或无机粉末混合的粘合树脂组成,并且在水分透湿防水层的内侧点涂或点印 。 纤维粉末或无机粉末具有高亲水性和吸湿性,其吸湿能力强,当制造衣物时,可以防止雨滴渗透,但可以使汗液蒸发蒸气透过织物。 而且,它能够吸收大量的汗水。
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10.
公开(公告)号:US5376208A
公开(公告)日:1994-12-27
申请号:US241406
申请日:1994-05-11
申请人: Shin-Chuan Yao , Jong-Fu Wu , Kun-Lin Cheng , Chiu-Hsiung Tsai , Farn-Ping Koong , Kun-Lung Chuang , Shu-Lan Yao , Chin-Liu Liu
发明人: Shin-Chuan Yao , Jong-Fu Wu , Kun-Lin Cheng , Chiu-Hsiung Tsai , Farn-Ping Koong , Kun-Lung Chuang , Shu-Lan Yao , Chin-Liu Liu
CPC分类号: D06N3/14 , D06N3/0059 , D06N3/0063 , Y10S428/921 , Y10S521/906 , Y10T428/249982 , Y10T428/249987 , Y10T442/2139 , Y10T442/2713
摘要: A water-permeable and fire-resistant product and the preparing method thereof is disclosed. The waterpermeable and fire-resistant product is made of a fabric layer and a purous film adhered thereon. The porous film of this invention comprises polyurethane resin; a first fire-resistant agent; a second fire-resistant agent, an inorganic fire-resistant agent and an additive agent. The first fire-resistant agent used is selected from the group consisting of paraffine chlorinated, decabromodiphenyl oxide, hexachloro benzene, hexabromo benzene, pentabromo ethyl benzene, pentabromo diphenyl oxide and octabromo diphenyl ether. The second fire-resistant agent used is selected from the group consisting of Sb2O3 and Sb2O5. The surface of the product produced is smooth.
摘要翻译: 公开了一种透水耐火制品及其制备方法。 耐水防火产品由粘合在其上的织物层和薄膜制成。 本发明的多孔膜包含聚氨酯树脂; 第一种耐火剂; 第二耐火剂,无机防火剂和添加剂。 所用的第一种耐火剂选自氯化,十溴二苯醚,六氯苯,六溴苯,五溴乙苯,五溴二苯氧化物和八溴二苯醚等组成的组。 所用的第二种耐火剂选自Sb2O3和Sb2O5。 所生产的产品的表面光滑。
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