MAGNETIC NANOMEDICINE FOR TUMOR SUPPRESSION AND THERAPY
    4.
    发明申请
    MAGNETIC NANOMEDICINE FOR TUMOR SUPPRESSION AND THERAPY 有权
    用于肿瘤抑制和治疗的磁性纳米微粒

    公开(公告)号:US20120328705A1

    公开(公告)日:2012-12-27

    申请号:US13166450

    申请日:2011-06-22

    CPC分类号: A61K31/704 A61K9/0009

    摘要: A magnetic nanomedicine for tumor suppression and therapy, comprising: a core, made of magnetic nanoparticles; a shell, encapsulating said core and is made of carboxylated polyaniline (SPAnH); and a tumor suppression medicine Epirubicin (EPI) or Doxorubicin (DOX) covalently bonded onto said shell. Said magnetic nanomedicine is capable of improving its thermal stability, and it can be dissolved uniformly in water, plus its superparamagnetic property, thus it can be guided by an outside magnetic field to concentrate to the site of tumor distribution to increase the local medicine concentration and enhance therapy effect.

    摘要翻译: 一种用于肿瘤抑制和治疗的磁性纳米医药,包括:由磁性纳米颗粒制成的核心; 壳,封装所述芯并由羧化聚苯胺(SPAnH)制成; 以及共价键合到所述壳上的肿瘤抑制药物表柔比星(EPI)或多柔比星(DOX)。 所述磁性纳米医药能够提高其热稳定性,可以均匀地溶解在水中,加上其超顺磁性,可以通过外界磁场引导,集中到肿瘤分布部位,增加局部药物浓度, 增强疗效。

    Magnetic nanomedicine for tumor suppression and therapy
    7.
    发明授权
    Magnetic nanomedicine for tumor suppression and therapy 有权
    用于肿瘤抑制和治疗的磁性纳米医学

    公开(公告)号:US08329222B1

    公开(公告)日:2012-12-11

    申请号:US13166450

    申请日:2011-06-22

    IPC分类号: A61K9/14 A61K9/16

    CPC分类号: A61K31/704 A61K9/0009

    摘要: A magnetic nanomedicine for tumor suppression and therapy, comprising: a core, made of magnetic nanoparticles; a shell, encapsulating said core and is made of carboxylated polyaniline (SPAnH); and a tumor suppression medicine Epirubicin (EPI) or Doxorubicin (DOX) covalently bonded onto said shell. Said magnetic nanomedicine is capable of improving its thermal stability, and it can be dissolved uniformly in water, plus its superparamagnetic property, thus it can be guided by an outside magnetic field to concentrate to the site of tumor distribution to increase the local medicine concentration and enhance therapy effect.

    摘要翻译: 一种用于肿瘤抑制和治疗的磁性纳米医药,包括:由磁性纳米颗粒制成的核心; 壳,封装所述芯并由羧化聚苯胺(SPAnH)制成; 以及共价键合到所述壳上的肿瘤抑制药物表柔比星(EPI)或多柔比星(DOX)。 所述磁性纳米医药能够提高其热稳定性,可以均匀地溶解在水中,加上其超顺磁性,可以通过外界磁场引导,集中到肿瘤分布部位,增加局部药物浓度, 增强疗效。