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公开(公告)号：US20100003353A1
公开(公告)日：2010-01-07
申请号：US12483073
申请日：2009-06-11
Applicant: Laura Stephens , John J. Masiz , Stephen G. Carter , Zhen Zhu , Kanu Patel
Inventor： Laura Stephens , John J. Masiz , Stephen G. Carter , Zhen Zhu , Kanu Patel
IPC: A61K31/197 , A61K31/4164 , A61K31/4406 , A61K31/295 , A61K31/137 , A61K31/437 , A61K36/00 , A61K36/886 , A61P17/00
CPC classification number: A61K41/0028 , A61K9/0014 , A61K31/137 , A61K31/17 , A61K31/198 , A61K31/295 , A61K31/401 , A61K31/4164 , A61K31/4166 , A61K31/425 , A61K31/455 , A61K31/522 , A61K36/14 , A61K36/16 , A61K36/185 , A61K36/28 , A61K36/53 , A61K36/62 , A61K36/734 , A61K36/752 , A61K36/88 , A61K36/886 , A61K36/8969 , A61K36/9068 , A61M37/00 , A61N5/062 , A61N7/00
Abstract: In a method for treating an affected skin region of a patient having a skin disorder, a vasodilation composition is applied to an affected skin region of a patient, the affected skin region exhibiting a skin disorder characterized by at least one abnormal blood vessel, and the affected skin region is then treated so as to non-invasively disrupt tissue architecture, e.g., by inducing ischemia, of the at least one abnormal blood vessel. A vasoconstriction composition can then be applied to the skin region to cause vasoconstriction of the at least one blood vessel in order to promote healing.
Abstract translation: 在用于治疗患有皮肤病的患者的受影响的皮肤区域的方法中，将血管舒张组合物施用于患者的受影响的皮肤区域，所述受影响的皮肤区域呈现以至少一种异常血管为特征的皮肤病， 然后治疗受影响的皮肤区域，以便非侵入性地破坏至少一个异常血管的组织结构，例如通过诱导缺血。 然后可以将血管收缩组合物施用于皮肤区域以引起至少一个血管的血管收缩以促进愈合。
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公开(公告)号：US20100145256A1
公开(公告)日：2010-06-10
申请号：US12631698
申请日：2009-12-04
Applicant: Stephen G. Carter , Zhen Zhu , Kanu Patel , Diane L. Kozwich , Laura Stephens , John J. Masiz , David H. Donabedian
Inventor： Stephen G. Carter , Zhen Zhu , Kanu Patel , Diane L. Kozwich , Laura Stephens , John J. Masiz , David H. Donabedian
CPC classification number: A61K8/4926 , A61B18/203 , A61B2017/00769 , A61B2018/00452 , A61B2018/0047 , A61K8/0208 , A61K8/26 , A61K8/342 , A61K8/498 , A61K8/585 , A61K8/678 , A61K8/73 , A61K8/922 , A61K2800/51 , A61K2800/74 , A61K2800/81 , A61K2800/91 , A61M37/0092 , A61N1/325 , A61N5/062 , A61Q1/145 , A61Q19/02
Abstract: Methods and formulations for removing a tattoo by using a cell disrupter in combination with a vasodilator, and optionally one or more of an osmotic modifying agent, a chelation agent, and an occlusive modifying agent. Embodiments optionally further include using one or more of an antibiotic, anesthetic, penetration enhancer, excipient, carrier and vehicle.
Abstract translation: 通过使用细胞破坏剂与血管扩张剂组合，以及任选的一种或多种渗透调节剂，螯合剂和闭塞性修饰剂来去除纹身的方法和制剂。 实施方案任选进一步包括使用抗生素，麻醉剂，渗透增强剂，赋形剂，载体和载体中的一种或多种。
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公开(公告)号：US09278233B2
公开(公告)日：2016-03-08
申请号：US12631698
申请日：2009-12-04
Applicant: Stephen G. Carter , Zhen Zhu , Kanu Patel , Diane L. Kozwich , Laura Stephens , John J. Masiz , David H. Donabedian
Inventor： Stephen G. Carter , Zhen Zhu , Kanu Patel , Diane L. Kozwich , Laura Stephens , John J. Masiz , David H. Donabedian
IPC: A61M37/00 , A61Q1/14 , A61B18/20 , A61K8/02 , A61K8/49 , A61K8/67 , A61Q19/02 , A61B17/00 , A61B18/00 , A61N1/32 , A61N5/06
CPC classification number: A61K8/4926 , A61B18/203 , A61B2017/00769 , A61B2018/00452 , A61B2018/0047 , A61K8/0208 , A61K8/26 , A61K8/342 , A61K8/498 , A61K8/585 , A61K8/678 , A61K8/73 , A61K8/922 , A61K2800/51 , A61K2800/74 , A61K2800/81 , A61K2800/91 , A61M37/0092 , A61N1/325 , A61N5/062 , A61Q1/145 , A61Q19/02
Abstract: Methods and formulations for removing a tattoo by using a cell disrupter in combination with a vasodilator, and optionally one or more of an osmotic modifying agent, a chelation agent, and an occlusive modifying agent. Embodiments optionally further include using one or more of an antibiotic, anesthetic, penetration enhancer, excipient, carrier and vehicle.
Abstract translation: 通过使用细胞破坏剂与血管扩张剂组合，以及任选的一种或多种渗透调节剂，螯合剂和闭塞性修饰剂来去除纹身的方法和制剂。 实施方案任选进一步包括使用抗生素，麻醉剂，渗透增强剂，赋形剂，载体和载体中的一种或多种。
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公开(公告)号：US08367122B2
公开(公告)日：2013-02-05
申请号：US12483073
申请日：2009-06-11
Applicant: Laura Stephens , John J. Masiz , Stephen G. Carter , Zhen Zhu , Kanu Patel
Inventor： Laura Stephens , John J. Masiz , Stephen G. Carter , Zhen Zhu , Kanu Patel
IPC: A61K36/886
CPC classification number: A61K41/0028 , A61K9/0014 , A61K31/137 , A61K31/17 , A61K31/198 , A61K31/295 , A61K31/401 , A61K31/4164 , A61K31/4166 , A61K31/425 , A61K31/455 , A61K31/522 , A61K36/14 , A61K36/16 , A61K36/185 , A61K36/28 , A61K36/53 , A61K36/62 , A61K36/734 , A61K36/752 , A61K36/88 , A61K36/886 , A61K36/8969 , A61K36/9068 , A61M37/00 , A61N5/062 , A61N7/00
Abstract: In a method for treating an affected skin region of a patient having a skin disorder, a vasodilation composition is applied to an affected skin region of a patient, the affected skin region exhibiting a skin disorder characterized by at least one abnormal blood vessel, and the affected skin region is then treated so as to non-invasively disrupt tissue architecture, e.g., by inducing ischemia, of the at least one abnormal blood vessel. A vasoconstriction composition can then be applied to the skin region to cause vasoconstriction of the at least one blood vessel in order to promote healing.
Abstract translation: 在用于治疗患有皮肤病的患者的受影响的皮肤区域的方法中，将血管舒张组合物施用于患者的受影响的皮肤区域，所述受影响的皮肤区域呈现以至少一种异常血管为特征的皮肤病， 然后治疗受影响的皮肤区域，以便非侵入性地破坏至少一个异常血管的组织结构，例如通过诱导缺血。 然后可以将血管收缩组合物施用于皮肤区域以引起至少一个血管的血管收缩以促进愈合。
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