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公开(公告)号:US20120027756A1
公开(公告)日:2012-02-02
申请号:US13242418
申请日:2011-09-23
申请人: Liqun DONG , Marc NASOFF
发明人: Liqun DONG , Marc NASOFF
CPC分类号: C07K16/28 , C07K2317/24 , C07K2317/565 , C07K2317/73 , C07K2317/76
摘要: Disclosed in the present invention are antibodies that specifically recognize and antagonize human TSLP receptor, and methods of employing these antibodies to treat or ameliorate diseases or disorder mediated by TSLP signaling.
摘要翻译: 在本发明中公开的是特异性识别和拮抗人TSLP受体的抗体,以及使用这些抗体治疗或改善由TSLP信号转导介导的疾病或病症的方法。
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公开(公告)号:US20050155389A1
公开(公告)日:2005-07-21
申请号:US10883638
申请日:2004-06-30
申请人: David Ho , Lianxun Feng , Liqun Dong , Xinhou Liu , Zhen Zhen
发明人: David Ho , Lianxun Feng , Liqun Dong , Xinhou Liu , Zhen Zhen
IPC分类号: B29C47/04 , B29C47/06 , B29C47/26 , B29C47/28 , B29C47/70 , B29D11/00 , B29L9/00 , C03B37/02
CPC分类号: B29D11/00663 , B29C48/05 , B29C48/21 , B29C48/30 , B29C48/304 , B29C48/335 , B29C48/338 , B29C48/34 , B29C48/705 , B29L2011/0075
摘要: A crosshead die for a plastic optical fiber fabrication system is provided. The crosshead die includes a body, an insert, mounting flanges on the upstream and downstream end for securing the crosshead die to adjacent equipment or another crosshead dies, an axial port for receiving a mixed molten material that makes up the core, and a radial port for receiving a mixed molten material that makes up the outer layering material to be co-extruded over the core. The die insert includes a material distribution channel system that provides substantially the same linear distance for the mixed molten material to travel prior to the co-extrusion. If multiple die inserts are utilized, the crosshead die is able to co-extrude multiple layers over the core. If the crosshead dies are serially assembled, additional concentric layers of material can be co-extruded atop the layered plastic optical fiber extruded from the upstream crosshead die.
摘要翻译: 提供了一种用于塑料光纤制造系统的十字头模具。 十字模具包括主体,插入件,上游和下游端的安装凸缘,用于将十字头模具固定到相邻设备或另一十字头模具,用于接收构成芯部的混合熔融材料的轴向端口和径向端口 用于接收构成外层材料的混合熔融材料在芯上共挤出。 模具插入件包括材料分配通道系统,其在混合熔融材料在共挤出之前提供基本相同的直线距离。 如果使用多个模具插入件,则十字头模具能够在芯上共挤出多个层。 如果十字头模具被串联组装,则可以在从上游十字头模具挤出的分层塑料光纤上共同挤出另外的同心层材料。
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公开(公告)号:US08097705B2
公开(公告)日:2012-01-17
申请号:US12160868
申请日:2007-01-11
申请人: Liqun Dong , Marc Nasoff
发明人: Liqun Dong , Marc Nasoff
CPC分类号: C07K16/28 , C07K2317/24 , C07K2317/565 , C07K2317/73 , C07K2317/76
摘要: Disclosed in the present invention are antibodies that specifically recognize and antagonize human TSLP receptor, and methods of employing these antibodies to treat or ameliorate diseases or disorder mediated by TSLP signaling.
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公开(公告)号:US20180346569A1
公开(公告)日:2018-12-06
申请号:US15777015
申请日:2016-11-17
发明人: Jieyi Wang , Liqun Dong , Yaolin Wang
CPC分类号: C07K16/2818 , A61K2039/505 , C07K2317/24 , C07K2317/70 , C07K2317/76 , C07K2317/92
摘要: Anti-PD-1 antibodies and uses thereof in treating diseases associated with the PD-1 signaling, such as cancer, infectious diseases such as viral infection or immune related diseases.
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公开(公告)号:US08101182B2
公开(公告)日:2012-01-24
申请号:US12141516
申请日:2008-06-18
申请人: Liqun Dong , Marc Nasoff
发明人: Liqun Dong , Marc Nasoff
IPC分类号: A61K39/395 , C07K16/00 , C12P21/08
CPC分类号: C07K16/2866 , C07K2317/21 , C07K2317/33 , C07K2317/55 , C07K2317/76
摘要: Disclosed in the present invention are antibodies that specifically recognize and antagonize human TSLP receptor, and methods of employing these antibodies to treat or ameliorate diseases or disorder mediated by TSLP signaling.
摘要翻译: 在本发明中公开的是特异性识别和拮抗人TSLP受体的抗体,以及使用这些抗体治疗或改善由TSLP信号转导介导的疾病或病症的方法。
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公开(公告)号:US20090286312A1
公开(公告)日:2009-11-19
申请号:US12160868
申请日:2007-01-11
申请人: Liqun Dong , Marc Nasoff
发明人: Liqun Dong , Marc Nasoff
CPC分类号: C07K16/28 , C07K2317/24 , C07K2317/565 , C07K2317/73 , C07K2317/76
摘要: Disclosed in the present invention are antibodies that specifically recognize and antagonize human TSLP receptor, and methods of employing these antibodies to treat or ameliorate diseases or disorder mediated by TSLP signaling.
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公开(公告)号:US20090074747A1
公开(公告)日:2009-03-19
申请号:US12141516
申请日:2008-06-18
申请人: Liqun DONG , Marc Nasoff
发明人: Liqun DONG , Marc Nasoff
IPC分类号: A61K39/395 , C07K16/00 , C07H21/04 , A61P37/08 , C12N5/10
CPC分类号: C07K16/2866 , C07K2317/21 , C07K2317/33 , C07K2317/55 , C07K2317/76
摘要: Disclosed in the present invention are antibodies that specifically recognize and antagonize human TSLP receptor, and methods of employing these antibodies to treat or ameliorate diseases or disorder mediated by TSLP signaling.
摘要翻译: 在本发明中公开的是特异性识别和拮抗人TSLP受体的抗体,以及使用这些抗体治疗或改善由TSLP信号转导介导的疾病或病症的方法。
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