公开(公告)号：US20130097576A1

公开(公告)日：2013-04-18

申请号：US13327771

申请日：2011-12-16

申请人： JIA-LU YE ,  CHIA-NAN PAI ,  SHOU-KUO HSU

发明人： JIA-LU YE ,  CHIA-NAN PAI ,  SHOU-KUO HSU

IPC分类号： G06F17/50

CPC分类号： G06F17/5036

摘要： A computer-based method and a computing device for checking stub lengths of via stubs of a printed circuit board (PCB) layout are provided. The computing device displays a check interface, selects signal transmission line from a currently run PCB layout through the check interface, receives a reference stub length input through the check interface, and determines the actual stub length of each via stub of each via each selected signal transmission line connected to. The computing device further determines that a design of one via stub satisfies the design standards, if the actual stub length of the one stub via is less than or equal to the reference length, and determines that a design of one via stub does not satisfy the design standards if the actual stub length of the one via stub is greater than the reference stub length.

摘要翻译： 提供了一种基于计算机的方法和用于检查印刷电路板（PCB）布局的通孔短截线的短截线长度的计算装置。 计算装置显示检查接口，通过检查接口从当前运行的PCB布局中选择信号传输线，接收通过检查接口输入的参考短截线长度，并通过每个选定信号确定每个通孔短截线的实际短截线长度 传输线连接。 如果一个存根通孔的实际短截线长度小于或等于参考长度，则计算设备还确定一个通孔存根的设计满足设计标准，并且确定一个通孔存储体的设计不满足 如果一个通过存根的实际存根长度大于参考短截线长度，则设计标准。

公开(公告)号：US08255864B2

公开(公告)日：2012-08-28

申请号：US12961908

申请日：2010-12-07

申请人： Jia-Lu Ye ,  Shi-Piao Luo ,  Chia-Nan Pai ,  Shou-Kuo Hsu

发明人： Jia-Lu Ye ,  Shi-Piao Luo ,  Chia-Nan Pai ,  Shou-Kuo Hsu

IPC分类号： G06F17/50

CPC分类号： G06F17/5081 ,  G06F2217/82

摘要： A computing device and a method selects a signal transmission line from a circuit board, computes an actual length of each line segment of the selected signal transmission line, and computes an actual distance between each line segment of the selected signal transmission line and a corresponding line segment of each neighboring signal transmission line. If each actual length is less than or equal to a corresponding reference length and each actual distance is more than or equal to a corresponding reference distance, the device and method determines a design of the selected signal transmission line satisfies the design standards. Otherwise, if any actual length is more than a corresponding reference length, or if any actual distance is less than a corresponding reference distance, the device and method determines the design of the signal transmission line does not satisfy the design standards.

摘要翻译： 计算装置和方法从电路板选择信号传输线，计算所选择的信号传输线的每个线段的实际长度，并且计算所选信号传输线的每个线段与对应线之间的实际距离 每个相邻信号传输线的段。 如果每个实际长度小于或等于对应的参考长度，并且每个实际距离大于或等于相应的参考距离，则设备和方法确定所选信号传输线的设计满足设计标准。 否则，如果任何实际长度大于相应的参考长度，或者如果任何实际距离小于相应的参考距离，则设备和方法确定信号传输线的设计不符合设计标准。

公开(公告)号：US20120030639A1

公开(公告)日：2012-02-02

申请号：US12961908

申请日：2010-12-07

申请人： JIA-LU YE ,  SHI-PIAO LUO ,  CHIA-NAN PAI ,  SHOU-KUO HSU

发明人： JIA-LU YE ,  SHI-PIAO LUO ,  CHIA-NAN PAI ,  SHOU-KUO HSU

IPC分类号： G06F17/50

CPC分类号： G06F17/5081 ,  G06F2217/82

摘要： A computing device and a method selects a signal transmission line from a circuit board, computes an actual length of each line segment of the selected signal transmission line, and computes an actual distance between each line segment of the selected signal transmission line and a corresponding line segment of each neighboring signal transmission line. If each actual length is less than or equal to a corresponding reference length and each actual distance is more than or equal to a corresponding reference distance, the device and method determines a design of the selected signal transmission line satisfies the design standards. Otherwise, if any actual length is more than a corresponding reference length, or if any actual distance is less than a corresponding reference distance, the device and method determines the design of the signal transmission line does not satisfy the design standards.

摘要翻译： 计算装置和方法从电路板选择信号传输线，计算所选择的信号传输线的每个线段的实际长度，并且计算所选信号传输线的每个线段与对应线之间的实际距离 每个相邻信号传输线的段。 如果每个实际长度小于或等于对应的参考长度，并且每个实际距离大于或等于相应的参考距离，则设备和方法确定所选信号传输线的设计满足设计标准。 否则，如果任何实际长度大于相应的参考长度，或者如果任何实际距离小于相应的参考距离，则设备和方法确定信号传输线的设计不符合设计标准。

公开(公告)号：US09186410B2

公开(公告)日：2015-11-17

申请号：US13581463

申请日：2011-03-01

申请人： Helen Burt ,  Donald Brooks ,  Jayachandran Kizhakkedathu ,  Richard Liggins ,  Dechi Guan ,  Lu Ye ,  Clement Mugabe ,  Alan So ,  Martin E. Gleave ,  John K. Jackson ,  Rajesh Kumar Kainthan

发明人： Helen Burt ,  Donald Brooks ,  Jayachandran Kizhakkedathu ,  Richard Liggins ,  Dechi Guan ,  Lu Ye ,  Clement Mugabe ,  Alan So ,  Martin E. Gleave ,  John K. Jackson ,  Rajesh Kumar Kainthan

IPC分类号： A61K33/24 ,  C07C217/00 ,  C07D207/46 ,  A61K47/10 ,  A61K9/51 ,  A61K47/34 ,  C08G65/34 ,  C08G65/48 ,  C08G83/00 ,  C08G65/333 ,  A61K9/00

CPC分类号： A61K47/10 ,  A61K9/0034 ,  A61K9/006 ,  A61K9/5146 ,  A61K31/337 ,  A61K31/407 ,  A61K33/24 ,  A61K47/34 ,  A61K47/60 ,  C08G65/33306 ,  C08G65/33337 ,  C08G65/34 ,  C08G65/48 ,  C08G83/005 ,  C08G83/006 ,  C08G2650/54

摘要： Herein are provided derivatized hyperbranched polyglycerols (“dHPGs”). The dHPG comprises a core comprising a hyperbranched polyglycerol derivatized with C1C20 alkyl chains and a shell comprising at least one hydrophilic substituent bound to hydroxyl groups of the core, wherein the hyperbranched polyglycerol comprises from about 1 to about 200 moles of the at least one hydrophilic substituent. The dHPGs are for use as agents for the delivery of a drug or other biologically active moiety to the urinary tract, the digestive tract, the airways, the vaginal cavity and cervix and the peritoneal cavity to treat indications such as cancer, which may be useful in the treatment of or the manufacture of a medicament, in the preparation, of a pharmaceutical composition for the treatment of cancer, as a pre-treatment or co-treatment to improve drug uptake in a tissue. Furthermore, there are provided methods of making dHPGs.

摘要翻译： 本文提供衍生的超支化聚甘油（“dHPG”）。 dHPG包含核心，其包含用C1C20烷基链衍生的超支化聚甘油和包含至少一个与核心羟基结合的亲水取代基的壳，其中超支化聚甘油包含约1至约200摩尔的至少一个亲水取代基 。 dHPG用作将药物或其他生物活性部分递送至尿路，消化道，气道，阴道腔和子宫颈以及腹膜腔以治疗诸如癌症的适应症的药剂，其可能是有用的 在制备中用于治疗癌症的药物组合物的治疗或制造中，作为用于改善组织中药物摄取的预处理或共处理。 此外，还提供了制造dHPG的方法。

公开(公告)号：US08510705B2

公开(公告)日：2013-08-13

申请号：US13327771

申请日：2011-12-16

申请人： Jia-Lu Ye ,  Chia-Nan Pai ,  Shou-Kuo Hsu

发明人： Jia-Lu Ye ,  Chia-Nan Pai ,  Shou-Kuo Hsu

IPC分类号： G06F17/50

CPC分类号： G06F17/5036

摘要： A computer-based method and a computing device for checking stub lengths of via stubs of a printed circuit board (PCB) layout are provided. The computing device displays a check interface, selects signal transmission line from a currently run PCB layout through the check interface, receives a reference stub length input through the check interface, and determines the actual stub length of each via stub of each via each selected signal transmission line connected to. The computing device further determines that a design of one via stub satisfies the design standards, if the actual stub length of the one stub via is less than or equal to the reference length, and determines that a design of one via stub does not satisfy the design standards if the actual stub length of the one via stub is greater than the reference stub length.

摘要翻译： 提供了一种基于计算机的方法和用于检查印刷电路板（PCB）布局的通孔短截线的短截线长度的计算装置。 计算装置显示检查接口，通过检查接口从当前运行的PCB布局中选择信号传输线，接收通过检查接口输入的参考短截线长度，并通过每个选定信号确定每个通孔短截线的实际短截线长度 传输线连接。 如果一个存根通孔的实际短截线长度小于或等于参考长度，则计算设备还确定一个通孔存根的设计满足设计标准，并且确定一个通孔存储体的设计不满足 如果一个通过存根的实际存根长度大于参考短截线长度，则设计标准。

公开(公告)号：US20130122112A1

公开(公告)日：2013-05-16

申请号：US13581463

申请日：2011-03-01

申请人： Helen M. Burt ,  Donald Brooks ,  Jayachandran Kizhakkedathu ,  Richard Liggins ,  Dechi Guan ,  Lu Ye ,  Clement Mugabe ,  Alan So ,  Martin E. Gleave ,  John K. Jackson ,  Rajesh Kumar Kainthan

发明人： Helen M. Burt ,  Donald Brooks ,  Jayachandran Kizhakkedathu ,  Richard Liggins ,  Dechi Guan ,  Lu Ye ,  Clement Mugabe ,  Alan So ,  Martin E. Gleave ,  John K. Jackson ,  Rajesh Kumar Kainthan

IPC分类号： A61K47/10 ,  C08G65/333

CPC分类号： A61K47/10 ,  A61K9/0034 ,  A61K9/006 ,  A61K9/5146 ,  A61K31/337 ,  A61K31/407 ,  A61K33/24 ,  A61K47/34 ,  A61K47/60 ,  C08G65/33306 ,  C08G65/33337 ,  C08G65/34 ,  C08G65/48 ,  C08G83/005 ,  C08G83/006 ,  C08G2650/54

摘要： Herein are provided derivatized hyperbranched polyglycerols (“dHPGs”). The dHPG comprises a core comprising a hyperbranched polyglycerol derivatized with C1C20 alkyl chains and a shell comprising at least one hydrophilic substituent bound to hydroxyl groups of the core, wherein the hyperbranched polyglycerol comprises from about 1 to about 200 moles of the at least one hydrophilic substituent. The dHPGs are for use as agents for the delivery of a drug or other biologically active moiety to the urinary tract, the digestive tract, the airways, the vaginal cavity and cervix and the peritoneal cavity to treat indications such as cancer, which may be useful in the treatment of or the manufacture of a medicament, in the preparation, of a pharmaceutical composition for the treatment of cancer, as a pre-treatment or co-treatment to improve drug uptake in a tissue. Furthermore, there are provided methods of making dHPGs.

摘要翻译： 本文提供衍生的超支化聚甘油（“dHPG”）。 dHPG包含核心，其包含用C1C20烷基链衍生的超支化聚甘油和包含至少一个与核心羟基结合的亲水取代基的壳，其中超支化聚甘油包含约1至约200摩尔的至少一个亲水取代基 。 dHPG用作将药物或其他生物活性部分递送至尿路，消化道，气道，阴道腔和子宫颈以及腹膜腔以治疗诸如癌症的适应症的药剂，其可能是有用的 在制备中用于治疗癌症的药物组合物的治疗或制造中，作为用于改善组织中药物摄取的预处理或共处理。 此外，还提供了制备dHPG的方法。