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公开(公告)号：US20130184284A1
公开(公告)日：2013-07-18
申请号：US13549767
申请日：2012-07-16
申请人： William R. Ewing , Yeheng Zhu , Chongqing Sun , Yanting Huang , Maheswaran Sivasamban Karatholuvhu , Scott A. Bolton , Laxman Pasunoori , Sunil Kumar Mandal , Philip M. Sher
发明人： William R. Ewing , Yeheng Zhu , Chongqing Sun , Yanting Huang , Maheswaran Sivasamban Karatholuvhu , Scott A. Bolton , Laxman Pasunoori , Sunil Kumar Mandal , Philip M. Sher
IPC分类号： A61K31/506 , A61K31/454 , A61K31/439 , C07D401/12 , A61K31/4545 , A61K45/06 , C07D401/14 , A61K31/498 , A61K31/501 , C07D471/04 , A61K31/437 , C07D413/12 , A61K31/497
CPC分类号： A61K31/506 , A61K31/437 , A61K31/439 , A61K31/454 , A61K31/4545 , A61K31/497 , A61K31/498 , A61K31/501 , A61K45/06 , C07D401/12 , C07D401/14 , C07D413/12 , C07D417/12 , C07D451/02 , C07D453/06 , C07D471/04 , C07D471/08
摘要： The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are agonists, partial agonists and modulators of the NPY Y4 receptor and may be used for the treatment and prophylaxis of various diseases and conditions.
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公开(公告)号：US08815909B2
公开(公告)日：2014-08-26
申请号：US13549767
申请日：2012-07-16
申请人： William R. Ewing , Yeheng Zhu , Chongqing Sun , Yanting Huang , Maheswaran Sivasamban Karatholuvhu , Scott A. Bolton , Laxman Pasunoori , Sunil Kumar Mandal , Philip M. Sher
发明人： William R. Ewing , Yeheng Zhu , Chongqing Sun , Yanting Huang , Maheswaran Sivasamban Karatholuvhu , Scott A. Bolton , Laxman Pasunoori , Sunil Kumar Mandal , Philip M. Sher
CPC分类号： A61K31/506 , A61K31/437 , A61K31/439 , A61K31/454 , A61K31/4545 , A61K31/497 , A61K31/498 , A61K31/501 , A61K45/06 , C07D401/12 , C07D401/14 , C07D413/12 , C07D417/12 , C07D451/02 , C07D453/06 , C07D471/04 , C07D471/08
摘要： The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are agonists, partial agonists and modulators of the NPY Y4 receptor and may be used for the treatment and prophylaxis of various diseases and conditions.
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公开(公告)号：US08710049B2
公开(公告)日：2014-04-29
申请号：US13549717
申请日：2012-07-16
申请人： William R. Ewing , Yeheng Zhu , Chongqing Sun , Yanting Huang , Maheswaran Sivasamban Karatholuvhu
发明人： William R. Ewing , Yeheng Zhu , Chongqing Sun , Yanting Huang , Maheswaran Sivasamban Karatholuvhu
IPC分类号： A61K31/55 , A61K31/4418 , C07D209/52 , A61K31/403 , C07D413/10 , A61K31/454 , C07D401/12 , C07D401/04 , A61K31/506 , C07D207/14 , A61K31/402 , A61K31/4545 , C07D223/12 , C07D417/12 , A61K45/06 , C07D211/56
CPC分类号： A61K31/55 , A61K31/402 , A61K31/403 , A61K31/4418 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K45/06 , C07D207/14 , C07D209/52 , C07D211/56 , C07D223/12 , C07D401/04 , C07D401/10 , C07D401/12 , C07D401/14 , C07D407/12 , C07D409/12 , C07D413/10 , C07D413/12 , C07D417/12 , C07D451/02 , C07D453/06 , C07D471/08
摘要： The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are agonists, partial agonists and modulators of the NPY Y4 receptor and may be used for the treatment and prophylaxis of various diseases and conditions.
摘要翻译： 本发明提供式（I）化合物或其立体异构体或其药学上可接受的盐，其中所有变量如本文所定义。 这些化合物是NPY Y4受体的激动剂，部分激动剂和调节剂，可用于治疗和预防各种疾病和病症。
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公开(公告)号：US20130184262A1
公开(公告)日：2013-07-18
申请号：US13549717
申请日：2012-07-16
申请人： William R. Ewing , Yeheng Zhu , Chongqing Sun , Yanting Huang , Maheswaran Sivasamban Karatholuvhu
发明人： William R. Ewing , Yeheng Zhu , Chongqing Sun , Yanting Huang , Maheswaran Sivasamban Karatholuvhu
IPC分类号： A61K31/55 , A61K31/4418 , C07D209/52 , A61K31/403 , C07D413/10 , A61K31/454 , C07D401/12 , C07D401/04 , A61K31/506 , C07D207/14 , A61K31/402 , A61K31/4545 , C07D223/12 , C07D417/12 , A61K45/06 , C07D211/56
CPC分类号： A61K31/55 , A61K31/402 , A61K31/403 , A61K31/4418 , A61K31/454 , A61K31/4545 , A61K31/506 , A61K45/06 , C07D207/14 , C07D209/52 , C07D211/56 , C07D223/12 , C07D401/04 , C07D401/10 , C07D401/12 , C07D401/14 , C07D407/12 , C07D409/12 , C07D413/10 , C07D413/12 , C07D417/12 , C07D451/02 , C07D453/06 , C07D471/08
摘要： The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are agonists, partial agonists and modulators of the NPY Y4 receptor and may be used for the treatment and prophylaxis of various diseases and conditions.
摘要翻译： 本发明提供式（I）化合物或其立体异构体或其药学上可接受的盐，其中所有变量如本文所定义。 这些化合物是NPY Y4受体的激动剂，部分激动剂和调节剂，可用于治疗和预防各种疾病和病症。
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