公开(公告)号：US06772766B2

公开(公告)日：2004-08-10

申请号：US10372883

申请日：2003-02-24

Applicant: Richard Gallo ,  Daniel Nahon ,  Mathieu-Philippe Aubert ,  Philippe Marchand ,  Marwan Abboud ,  Steven G. Arless ,  Marc Dubuc ,  Sean Carroll ,  Dan Wittenberger ,  John W. Lehmann

Inventor： Richard Gallo ,  Daniel Nahon ,  Mathieu-Philippe Aubert ,  Philippe Marchand ,  Marwan Abboud ,  Steven G. Arless ,  Marc Dubuc ,  Sean Carroll ,  Dan Wittenberger ,  John W. Lehmann

IPC: A61B1900

CPC classification number: A61B18/02 ,  A61B2017/00292 ,  A61B2018/0212 ,  A61F2250/0067

Abstract: A method of promoting blood vessel growth includes the steps of providing a cryocatheter having a thermally transmission region; placing the cryocatheter proximate an area of tissue to be treated; cooling the thermally transmissive region of the cryocatheter proximate the area of tissue to a temperature sufficient to injure the area of tissue; allowing the area of tissue to warm; and removing the cryocatheter from the area of tissue. Prior, during or after the cooling step, the area of tissue can be mechanically traumatized, and drugs can be injected into the tissue.

Abstract translation: 促进血管生长的方法包括提供具有热传递区域的低温摄取机的步骤; 将低温套管放置在待处理组织的一个区域附近; 将靠近组织区域的低温热管的热传导区域冷却到足以损伤组织面积的温度; 允许组织的面积温暖​​; 并从组织区域移除低温切片机。 之前，在冷却步骤期间或之后，组织的面积可以被机械地创伤，药物可以被注射到组织中。

公开(公告)号：US06546932B1

公开(公告)日：2003-04-15

申请号：US09543108

申请日：2000-04-05

Applicant: Daniel Nahon ,  Mathieu-Philippe Aubert ,  Philippe Marchand ,  Marwan Abboud ,  Steven G. Arless ,  Richard Gallo ,  Marc Dubuc ,  Sean Carroll ,  Dan Wittenberger ,  John W. Lehmann

Inventor： Daniel Nahon ,  Mathieu-Philippe Aubert ,  Philippe Marchand ,  Marwan Abboud ,  Steven G. Arless ,  Richard Gallo ,  Marc Dubuc ,  Sean Carroll ,  Dan Wittenberger ,  John W. Lehmann

IPC: A61B1900

CPC classification number: A61B18/02 ,  A61B2017/00292 ,  A61B2018/0212 ,  A61F2250/0067

Abstract: A method of promoting blood vessel growth includes the steps of providing a cryocatheter having a thermally transmission region; placing the cryocatheter proximate an area of tissue to be treated; cooling the thermally transmissive region of the cryocatheter proximate the area of tissue to a temperature sufficient to injure the area of tissue; allowing the area of tissue to warm; and removing the cryocatheter from the area of tissue. Prior, during or after the cooling step, the area of tissue can be mechanically traumatized, and drugs can be injected into the tissue.

Abstract translation: 促进血管生长的方法包括以下步骤：提供具有热传递区域的低温容器; 将低温套管放置在待处理组织的一个区域附近; 将靠近组织区域的低温热管的热传导区域冷却到足以损伤组织面积的温度; 允许组织的面积温暖​​; 并从组织区域移除低温切片机。 之前，在冷却步骤期间或之后，组织的面积可以被机械地创伤，药物可以被注射到组织中。

公开(公告)号：US06401390B1

公开(公告)日：2002-06-11

申请号：US09633102

申请日：2000-08-04

Applicant: Michel Labbé ,  Marc Dubuc

Inventor： Michel Labbé ,  Marc Dubuc

IPC: A01G700

CPC classification number: D21H19/28 ,  B32B29/06 ,  C09D167/04 ,  D21H11/14 ,  D21H23/46

Abstract: This invention relates to a mulch having a preprogrammed biodegradability comprising at least two different layers of biodegradable polymer coated onto a sheet of a cellulosic material, one of these layers being a layer of polylactide. The mulch is particularly useful to control weeds in agriculture, horticulture, and forestry industries. The biodegradability of the mulch can further be preprogrammed according to the type of soil, the climatological zone, and the specific applications wherefore it is intended to be used. The present invention is also directed to methods for preparing and using the multilayer coated mulch.

Abstract translation: 本发明涉及具有预编程的生物降解性的覆盖物，其包括涂覆在纤维素材料片上的至少两层可生物降解的聚合物，其中一层是聚丙交酯层。 覆盖物对于控制农业，园艺和林业行业的杂草尤其有用。 根据土壤类型，气候区域以及旨在使用的具体应用，可以进一步对覆盖物的生物降解性进行预编程。 本发明还涉及制备和使用多层涂覆的覆盖物的方法。

公开(公告)号：US5311873A

公开(公告)日：1994-05-17

申请号：US937487

申请日：1992-08-28

Applicant: Pierre Savard ,  Reginald Nadeau ,  Marc Dubuc

Inventor： Pierre Savard ,  Reginald Nadeau ,  Marc Dubuc

IPC: A61N1/08 ,  A61N1/36 ,  A61N1/372 ,  A61N1/00

CPC classification number: A61N1/36014 ,  A61N1/08 ,  A61N1/372 ,  A61B2034/2053

Abstract: Body surface potential map (BSPM) pace-mapping is a system and method that can be used in medicine to localize with precision the site of origin of abnormal cardiac electrical activity and to guide the positioning of a catheter over this site of origin, such as the site of ventricular preexcitation in patients with the Wolff-Parkinson-White syndrome or the focus of ectopic activity in patients with tachycardia. Body surface potential distributions are measured with a large number of electrodes, e.g. 24 to 128, distributed over the entire torso surface. The electrical signals are first amplified, converted into digital data and treated to remove electrical or muscle artifacts. Data recorded during abnormal activation (reference beat) are aligned with data recorded during cardiac pacing (paced beat) so as to maximize the average value of the correlation coefficient between the reference and the paced potential distributions during a preset time interval following the beginning of the QRS complex. Reference and paced maps showing color-coded isopotential contour lines are displayed side by side for the same time instant. Visual analysis of these maps according to previously published criteria determines the relative position of the pacing catheter with respect to the focus of abnormal activation, and gives information so as to guide the catheter toward the focus.

Abstract translation: 身体表面电位图（BSPM）速度绘图是一种可用于医学中的系统和方法，用于精确定位异常心脏电活动的原点，并引导导管在该原点位置的定位，例如 患有Wolff-Parkinson-White综合征患者心室预激的部位或心动过速患者异位活动的重点。 用大量的电极测量体表面电位分布，例如， 24到128，分布在整个躯干表面。 电信号首先被放大，转换成数字数据并被处理以去除电或肌肉伪像。 在异常激活期间记录的数据（参考拍子）与在心脏起搏（起搏节拍）期间记录的数据对准，以便在开始之后的预设时间间隔期间使参考和起搏电位分布之间的相关系数的平均值最大化 QRS综合 显示彩色等电位轮廓线的参考和节奏地图在同一时刻并排显示。 根据先前发布的标准的这些图的视觉分析确定起搏导管相对于异常激活的焦点的相对位置，并且给出信息以引导导管朝向焦点。