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    Method and device for epicardial ablation
    3.
    发明授权
    Method and device for epicardial ablation 有权
    心外膜消融的方法和装置

    公开(公告)号：US07794454B2

    公开(公告)日：2010-09-14

    申请号：US10839979

    申请日：2004-05-04

    申请人： Marwan Abboud ,  Dan Wittenberger ,  Daniel Nahon ,  Steven G. Arless

    发明人： Marwan Abboud ,  Dan Wittenberger ,  Daniel Nahon ,  Steven G. Arless

    IPC分类号： A61B18/02

    CPC分类号： A61B18/02

    摘要： A method is disclosed for treating heart and vascular tissue with cryotreatment. A medical instrument, such as a catheter is positioned to contact a target region of cardiac tissue such as the epicardial tissue. The instrument or catheter provided includes a cryotreatment element that has thermally-transmissive properties. The cryotreatment element may be a cryochamber for enclosing the flow of a fluid refrigerant therein. The cryotreatment element is disposed at the situs of heart or vascular tissue to be treated, usually by piercing the epicardium sac via an opening in the patient's body. A refrigerant flow within the cryochamber creates endothermic cooling with respect to the targeted heart or vascular tissue, inducing hypothermia and forming iceballs proximate the tissue. The cooling may be reversible and non-permanent, or may be permanent leading to cell death, necrosis, apoptosis and/or surgical excision or ablation of tissue.

    摘要翻译： 公开了一种用冷冻治疗来治疗心脏和血管组织的方法。 诸如导管的医疗器械定位成接触诸如心外膜组织的心脏组织的靶区域。 提供的仪器或导管包括具有热传递特性的冷冻处理元件。 冷冻处理元件可以是用于封闭其中的流体制冷剂的流动的冷冻箱。 冷冻治疗元件设置在待治疗的心脏或血管组织的位置，通常通过穿过患者体内的开口刺穿心外膜。 冷冻箱内的制冷剂流动相对于目标心脏或血管组织产生吸热冷却，诱导低体温并在组织附近形成冰球。 冷却可以是可逆的和非永久性的，或者可能是永久性的导致细胞死亡，坏死，凋亡和/或手术切除或消融组织。

    Method and device for epicardial ablation
    4.
    发明授权
    Method and device for epicardial ablation 失效
    心外膜消融的方法和装置

    公开(公告)号：US07625369B2

    公开(公告)日：2009-12-01

    申请号：US11526494

    申请日：2006-09-25

    申请人： Marwan Abboud ,  Dan Wittenberger ,  Daniel Nahon ,  Steven G. Arless

    发明人： Marwan Abboud ,  Dan Wittenberger ,  Daniel Nahon ,  Steven G. Arless

    IPC分类号： A61B18/02

    CPC分类号： A61B18/02

    摘要： A method is disclosed for treating heart and vascular tissue with cryotreatment. A medical instrument, such as a catheter is positioned to contact a target region of cardiac tissue such as the epicardial tissue. The instrument or catheter provided includes a cryotreatment element that has thermally-transmissive properties. The cryotreatment element may be a cryochamber for enclosing the flow of a fluid refrigerant therein. The cryotreatment element is disposed at the situs of heart or vascular tissue to be treated, usually by piercing the epicardium sac via an opening in the patient's body. A refrigerant flow within the cryochamber creates endothermic cooling with respect to the targeted heart or vascular tissue, inducing hypothermia and forming iceballs proximate the tissue. The cooling may be reversible and non-permanent, or may be permanent leading to cell death, necrosis, apoptosis and/or surgical excision or ablation of tissue.

    摘要翻译： 公开了一种用冷冻治疗来治疗心脏和血管组织的方法。 诸如导管的医疗器械定位成接触诸如心外膜组织的心脏组织的靶区域。 提供的仪器或导管包括具有热传递特性的冷冻处理元件。 冷冻处理元件可以是用于封闭其中的流体制冷剂的流动的冷冻箱。 冷冻治疗元件设置在待治疗的心脏或血管组织的位置，通常通过穿过患者体内的开口刺穿心外膜。 冷冻箱内的制冷剂流动相对于目标心脏或血管组织产生吸热冷却，诱导低体温并在组织附近形成冰球。 冷却可以是可逆的和非永久性的，或者可能是永久性的导致细胞死亡，坏死，凋亡和/或手术切除或消融组织。