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公开(公告)号：US08285384B2
公开(公告)日：2012-10-09
申请号：US11654917
申请日：2007-01-17
申请人： Geoffrey Ball , Marcus Schmidt
发明人： Geoffrey Ball , Marcus Schmidt
IPC分类号： A61N1/36
CPC分类号： A61N1/0541 , A61N1/36036 , H04R25/606
摘要： Devices with both electrical and mechanical signal transducers can be used for improving sound perception by individuals with severe to profound hearing loss or tinnitus.
摘要翻译： 具有电和机械信号传感器的设备可用于改善具有严重到严重听力损失或耳鸣的个体的声音感知。
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2.发明申请Methods of Preparing, Optionally Supported, Ordered Intermetallic Palladium Gallium Compounds, the Compounds, as such, and Their Use in Catalysis 审中-公开制备任选支持的有序金属间化合物钯化合物的方法，化合物，以及它们在催化中的应用公开(公告)号：US20100261939A1
公开(公告)日：2010-10-14
申请号：US12742488
申请日：2008-10-29
申请人： Marc Armbruester , Marcus Schmidt , Kirill Kovnir , Matthias Friedrich , Karina Weinhold , Juri Grin , Robert Schloegl
发明人： Marc Armbruester , Marcus Schmidt , Kirill Kovnir , Matthias Friedrich , Karina Weinhold , Juri Grin , Robert Schloegl
CPC分类号： B01J23/62 , B01J21/04 , B01J21/08 , B01J35/0013 , B01J37/0201 , B01J37/16 , C07C5/09 , C07C7/167 , C07C2521/18 , C07C2523/08 , C07C2523/44 , C22C1/00 , Y02P20/52 , C07C11/04
摘要： The present invention pertains to methods of preparing optionally supported, ordered intermetallic palladium gallium compounds, and the corresponding, optionally supported, intermetallic palladium gallium compounds obtainable by these methods. The present invention also pertains to the use of the optionally supported ordered intermetallic palladium gallium compounds as catalysts, such as in selective hydrogenations of alkynes, in particular ethyne, to give the corresponding alkenes. The optionally supported, ordered intermetallic palladium gallium compounds were found to be highly active and selective catalysts in the above hydrogenation reactions.
摘要翻译： 本发明涉及制备任选负载的有序金属间钯镓化合物的方法，以及通过这些方法获得的相应的任选负载的金属间钯钯化合物的方法。 本发明还涉及使用任选支持的有序金属间钯镓化合物作为催化剂，例如在炔的选择性氢化，特别是乙炔中，得到相应的烯烃。 在上述氢化反应中，发现任选负载的有序金属间钯镓化合物是高活性和选择性的催化剂。
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公开(公告)号：US20100135879A1
公开(公告)日：2010-06-03
申请号：US12530580
申请日：2008-02-16
申请人： Martin Roesch , Dieter Lindner , Raoul Klingmann , Patrizia Laura , Joerg-Michael Richter , Marcus Schmidt
发明人： Martin Roesch , Dieter Lindner , Raoul Klingmann , Patrizia Laura , Joerg-Michael Richter , Marcus Schmidt
CPC分类号： B01J37/0244 , B01D53/945 , B01D2255/1021 , B01D2255/1023 , B01D2255/1025 , B01D2255/2042 , B01D2255/407 , B01D2255/9022 , B01J23/44 , B01J23/464 , B01J23/63 , Y02A50/2324 , Y02T10/22
摘要： A double-layer three-way catalyst is presented, which is formed from a catalytic coating applied directly to an inert honeycomb and a catalytically active coating thereon, and is suitable especially for cleaning of exhaust gases of motor vehicles with gasoline-operated internal combustion engines. The catalyst contains, in each layer, an active aluminum oxide and a cerium/zirconium mixed oxide, both of which are catalytically activated by palladium. The second layer on the gas side contains not only palladium but also rhodium, which is applied to the active aluminum oxide and the cerium/zirconium mixed oxide of the second layer in addition to the palladium. The cerium/zirconium mixed oxide of the second layer has a higher zirconium oxide content than the cerium/zirconium mixed oxide of the first layer. The catalyst is notable for exceptional activity coupled with outstanding aging stability.
摘要翻译： 提出了一种双层三元催化剂，其由直接施加到惰性蜂窝体上的催化涂层和其上的催化活性涂层形成，并且特别适用于用汽油操作的内燃机清洁机动车辆的废气 。 催化剂在每层中含有活性氧化铝和铈/锆混合氧化物，它们均由钯催化活化。 除了钯之外，气体侧的第二层不仅包含钯而且还包含铑，其施加到活性氧化铝和第二层的铈/锆混合氧化物。 第二层的铈/锆混合氧化物具有比第一层的铈/锆混合氧化物更高的氧化锆含量。 该催化剂值得注意的是出色的活性和突出的老化稳定性。
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公开(公告)号：US20070282397A1
公开(公告)日：2007-12-06
申请号：US11654917
申请日：2007-01-17
申请人： Geoffrey Ball , Marcus Schmidt
发明人： Geoffrey Ball , Marcus Schmidt
IPC分类号： H04R25/00
CPC分类号： A61N1/0541 , A61N1/36036 , H04R25/606
摘要： The present invention relates to implantable medical devices for improving sound perception by individuals with severe to profound hearing loss or tinnitus. In particular, the present invention provides methods and devices for stimulating structures of the ear via multiple signal transducers.
摘要翻译： 本发明涉及用于改善具有严重到严重听力损失或耳鸣的个体的声音感知的可植入医疗装置。 特别地，本发明提供了用于通过多个信号传感器刺激耳朵的结构的方法和装置。
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公开(公告)号：US20110172928A1
公开(公告)日：2011-07-14
申请号：US12999406
申请日：2009-06-16
IPC分类号： G06F19/00
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , G16B20/00 , G16B25/00 , G16B40/00
摘要： The present invention relates to methods for prediction of an outcome of neoplastic disease or cancer. More specifically, the present invention relates to a method for the prediction of breast cancer by determining in a biological sample from said patient an expression level of a plurality of genes selected from the group consisting of ACTG1, CA12, CALM2, CCND1, CHPT1, CLEC2B, CTSB, CXCL13, DCN, DHRS2, EIF4B, ERBB2, ESR1, FBXO28, GABRP, GAPDH, H2AFZ, IGFBP3, IGHG1, IGKC, KCTD3, KIAA0101, KRT17, MLPH, MMP1, NAT1, NEK2, NR2F2, OAZ1, PCNA, PDLIM5, PGR, PPIA, PRC1, RACGAP1, RPL37A, SOX4, TOP2A, UBE2C and VEGF.
摘要翻译： 本发明涉及用于预测肿瘤性疾病或癌症的结果的方法。 更具体地，本发明涉及通过在来自所述患者的生物样品中测定多种选自ACTG1，CA12，CALM2，CCND1，CHPT1，CLEC2B的多种基因的表达水平来预测乳腺癌的方法 ，CTSB，CXCL13，DCN，DHRS2，EIF4B，ERBB2，ESR1，FBXO28，GABRP，GAPDH，H2AFZ，IGFBP3，IGHG1，IGKC，KCTD3，KIAA0101，KRT17，MLPH，MMP1，NAT1，NEK2，NR2F2，OAZ1，PCNA，PDLIM5 ，PGR，PPIA，PRC1，RACGAP1，RPL37A，SOX4，TOP2A，UBE2C和VEGF。
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公开(公告)号：US20100305677A1
公开(公告)日：2010-12-02
申请号：US12849123
申请日：2010-08-03
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , A61F2002/183 , A61N1/36036
摘要： An implantable fixation structure includes a c-shape bone fixation clip adapted to fit over and attach to a bony bridge element in the middle ear of a patient. A c-shape electrode fixation clip is adapted to fit over and attach to an electrode array element in the middle ear of the patient. A connecting bar has a first end connected to the bone fixation clip and a second end connected to the electrode fixation clip. A coupling clip is connected to the connecting bar between the first end and the second end and adapted to fit over and attach to a cochlear implant element and hold the cochlear implant element in a desired position relative to the middle ear of the patient.
摘要翻译： 可植入固定结构包括适于安装在患者的中耳中并附着到骨桥元件的c形骨固定夹。 c形电极固定夹适于装配在患者的中耳中并附着到患者的中耳中的电极阵列元件。 连接杆具有连接到骨固定夹的第一端和连接到电极固定夹的第二端。 耦合夹在第一端和第二端之间连接到连接杆，并且适于安装在耳蜗植入元件上并附接到耳蜗植入元件并将耳蜗植入物元件相对于患者的中耳保持在期望的位置。
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公开(公告)号：US09517462B2
公开(公告)日：2016-12-13
申请号：US12530580
申请日：2008-02-16
申请人： Martin Roesch , Dieter Linder , Raoul Klingmann , Patrizia Laura De Cola , Joerg-Michael Richter , Marcus Schmidt
发明人： Martin Roesch , Dieter Linder , Raoul Klingmann , Patrizia Laura De Cola , Joerg-Michael Richter , Marcus Schmidt
IPC分类号： B01J23/00 , B01J23/10 , B01J25/00 , B01J21/00 , B01J29/00 , B01J37/02 , B01D53/94 , B01J23/63 , B01J23/44 , B01J23/46
CPC分类号： B01J37/0244 , B01D53/945 , B01D2255/1021 , B01D2255/1023 , B01D2255/1025 , B01D2255/2042 , B01D2255/407 , B01D2255/9022 , B01J23/44 , B01J23/464 , B01J23/63 , Y02A50/2324 , Y02T10/22
摘要： A double-layer three-way catalyst is presented, which is formed from a catalytic coating applied directly to an inert honeycomb and a catalytically active coating thereon, and is suitable especially for cleaning of exhaust gases of motor vehicles with gasoline-operated internal combustion engines. The catalyst contains, in each layer, an active aluminum oxide and a cerium/zirconium mixed oxide, both of which are catalytically activated by palladium. The second layer on the gas side contains not only palladium but also rhodium, which is applied to the active aluminum oxide and the cerium/zirconium mixed oxide of the second layer in addition to the palladium. The cerium/zirconium mixed oxide of the second layer has a higher zirconium oxide content than the cerium/zirconium mixed oxide of the first layer. The catalyst is notable for exceptional activity coupled with outstanding aging stability.
摘要翻译： 提出了一种双层三元催化剂，其由直接施加到惰性蜂窝体上的催化涂层和其上的催化活性涂层形成，并且特别适用于用汽油操作的内燃机清洁机动车辆的废气 。 催化剂在每层中含有活性氧化铝和铈/锆混合氧化物，它们均由钯催化活化。 除了钯之外，气体侧的第二层不仅包含钯而且还包含铑，其施加到活性氧化铝和第二层的铈/锆混合氧化物。 第二层的铈/锆混合氧化物具有比第一层的铈/锆混合氧化物更高的氧化锆含量。 该催化剂值得注意的是出色的活性和突出的老化稳定性。
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8.发明授权Use of a mixture of an ordered intermetallic compound and an inert material as a catalyst and corresponding hydrogenation processes 有权使用有序金属间化合物和惰性材料的混合物作为催化剂和相应的氢化方法公开(公告)号：US08519207B2
公开(公告)日：2013-08-27
申请号：US12678774
申请日：2008-09-18
申请人： Marc Armbruester , Marcus Schmidt , Kirill Kovnir , Matthias Friedrich , Karina Weinhold , Juri Grin , Robert Schloegl
发明人： Marc Armbruester , Marcus Schmidt , Kirill Kovnir , Matthias Friedrich , Karina Weinhold , Juri Grin , Robert Schloegl
摘要： The present invention relates to a process for the hydrogenation, in particular selective hydrogenation of at least one unsaturated hydrocarbon compound comprising reacting the at least one unsaturated hydrocarbon compound with hydrogen in the presence of a hydrogenation catalyst, wherein the hydrogenation catalyst comprises a mixture of an ordered intermetallic compound and an inert material. According to another aspect, the present invention is concerned with the use of a mixture of at least one ordered intermetallic compound and at least one inert material, as a catalyst. The mixtures for use as a catalyst in the present invention can be prepared easily and achieve a superior activity in relation to the prior art, while preserving the high selectivity to the target compounds, e.g. in the selective hydrogenation of acetylene to ethylene.
摘要翻译： 本发明涉及一种用于氢化，特别是至少一种不饱和烃化合物的选择性氢化的方法，包括在氢化催化剂存在下使至少一种不饱和烃化合物与氢反应，其中氢化催化剂包括 有序金属间化合物和惰性材料。 根据另一方面，本发明涉及使用至少一种有序金属间化合物和至少一种惰性材料的混合物作为催化剂。 在本发明中用作催化剂的混合物可以容易地制备并且相对于现有技术获得优异的活性，同时保持对目标化合物的高选择性。 在乙炔选择性氢化成乙烯。
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公开(公告)号：US08160715B2
公开(公告)日：2012-04-17
申请号：US12849123
申请日：2010-08-03
IPC分类号： A61N1/375
CPC分类号： A61N1/0541 , A61F2002/183 , A61N1/36036
摘要： An implantable fixation structure includes a c-shape bone fixation clip adapted to fit over and attach to a bony bridge element in the middle ear of a patient. A c-shape electrode fixation clip is adapted to fit over and attach to an electrode array element in the middle ear of the patient. A connecting bar has a first end connected to the bone fixation clip and a second end connected to the electrode fixation clip. A coupling clip is connected to the connecting bar between the first end and the second end and adapted to fit over and attach to a cochlear implant element and hold the cochlear implant element in a desired position relative to the middle ear of the patient.
摘要翻译： 可植入固定结构包括适于安装在患者的中耳中并附着到骨桥元件的c形骨固定夹。 c形电极固定夹适于装配在患者的中耳中并附着到患者的中耳中的电极阵列元件。 连接杆具有连接到骨固定夹的第一端和连接到电极固定夹的第二端。 耦合夹在第一端和第二端之间连接到连接杆，并且适于安装在耳蜗植入元件上并附接到耳蜗植入元件并将耳蜗植入物元件相对于患者的中耳保持在期望的位置。
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公开(公告)号：US20120053842A9
公开(公告)日：2012-03-01
申请号：US12999406
申请日：2009-06-16
IPC分类号： G06F19/00
CPC分类号： G06F19/24 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , G06F19/18 , G06F19/20
摘要： The present invention relates to methods for prediction of an outcome of neoplastic disease or cancer. More specifically, the present invention relates to a method for the prediction of breast cancer by determining in a biological sample from said patient an expression level of a plurality of genes selected from the group consisting of ACTG1, CA12, CALM2, CCND1, CHPT1, CLEC2B, CTSB, CXCL13, DCN, DHRS2, EIF4B, ERBB2, ESR1, FBXO28, GABRP, GAPDH, H2AFZ, IGFBP3, IGHG1, IGKC, KCTD3, KIAA0101, KRT17, MLPH, MMP1, NAT1, NEK2, NR2F2, OAZ1, PCNA, PDLIM5, PGR, PPIA, PRC1, RACGAP1, RPL37A, SOX4, TOP2A, UBE2C and VEGF.
摘要翻译： 本发明涉及用于预测肿瘤性疾病或癌症的结果的方法。 更具体地，本发明涉及通过在来自所述患者的生物样品中测定多种选自ACTG1，CA12，CALM2，CCND1，CHPT1，CLEC2B的多种基因的表达水平来预测乳腺癌的方法 ，CTSB，CXCL13，DCN，DHRS2，EIF4B，ERBB2，ESR1，FBXO28，GABRP，GAPDH，H2AFZ，IGFBP3，IGHG1，IGKC，KCTD3，KIAA0101，KRT17，MLPH，MMP1，NAT1，NEK2，NR2F2，OAZ1，PCNA，PDLIM5 ，PGR，PPIA，PRC1，RACGAP1，RPL37A，SOX4，TOP2A，UBE2C和VEGF。
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