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1.发明申请AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME 审中-公开作为离子通道配体和药物组合物的酰胺衍生物及其使用方法公开(公告)号：US20120088746A1
公开(公告)日：2012-04-12
申请号：US12227197
申请日：2007-05-10
申请人： Yuji Shishido , Kazunari Nakao , Satoshi Nagayama , Hirotaka Tanaka , Matthew Alexander James Duncton , Matthew Cox , John Kincaid , Kiran Sahasrabudhe , Maria de Los Angeles Estiarte-Martinez
发明人： Yuji Shishido , Kazunari Nakao , Satoshi Nagayama , Hirotaka Tanaka , Matthew Alexander James Duncton , Matthew Cox , John Kincaid , Kiran Sahasrabudhe , Maria de Los Angeles Estiarte-Martinez
IPC分类号： A61K31/397 , C07D213/76 , C07D215/48 , C07D215/54 , C07D295/155 , C07D205/04 , A61K31/18 , A61K31/44 , A61K31/47 , A61K31/402 , A61K31/5375 , A61K31/451 , A61P19/02 , A61P19/08 , A61P1/00 , A61P25/16 , A61P29/00 , A61P25/28 , A61P25/18 , A61P25/22 , A61P25/08 , A61P13/00 , A61P13/12 , A61P13/10 , A61P9/12 , A61P35/00 , A61P3/04 , A61P3/00 , A61P17/06 , A61P17/14 , A61P17/04 , A61P9/10 , A61P11/00 , A61P11/06 , A61P25/00 , C07C311/16
CPC分类号： C07D215/48 , C07C311/08 , C07C2601/02 , C07D205/04 , C07D215/54 , C07D217/26 , C07D231/12 , C07D239/94 , C07D241/44 , C07D295/155 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/12 , C07D471/04 , C07D498/04 , C07D498/12
摘要： Compounds are disclosed that have a formula represented by the following: Formula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
摘要翻译： 公开了具有由下式表示的式的化合物：式（I）。 化合物可以制备成药物组合物，并且可以用于预防和治疗包括人在内的哺乳动物中的各种病症，包括作为非限制性实例，疼痛，炎症，创伤性损伤等。
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2.发明申请AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME 审中-公开作为离子通道配体和药物组合物的酰胺衍生物及其使用方法公开(公告)号：US20130045973A1
公开(公告)日：2013-02-21
申请号：US13452443
申请日：2012-04-20
申请人： Matthew Duncton , Donogh John Roger O'Mahony , Matthew Cox , Maria De Los Angeles Estiarte-Martinez
发明人： Matthew Duncton , Donogh John Roger O'Mahony , Matthew Cox , Maria De Los Angeles Estiarte-Martinez
IPC分类号： A61K31/4709 , A61K31/416 , C07D513/04 , A61K31/437 , C07D413/12 , A61K31/538 , C07D491/052 , A61K31/436 , C07D498/04 , A61K31/5365 , A61P29/00 , A61P25/16 , A61P25/28 , A61P25/00 , A61P25/06 , A61P25/24 , A61P25/22 , A61P25/18 , A61P25/20 , A61P13/10 , A61P11/00 , A61P11/06 , A61P25/08 , A61P11/02 , A61P37/08 , A61P13/00 , A61P19/02 , A61P1/00 , A61P37/00 , A61P9/10 , A61P19/08 , C07D405/12
CPC分类号： C07D405/12 , C07D401/12 , C07D498/04 , C07D513/04
摘要： Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
摘要翻译： 公开了具有下列化学式的化合物：化合物可以制备成药物组合物，并且可以用于预防和治疗哺乳动物包括人的多种病症，包括作为非限制性实例的疼痛 ，炎症，创伤性损伤等。
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3.发明授权Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same 失效酰胺衍生物作为离子通道配体和药物组合物及其使用方法公开(公告)号：US08153651B2
公开(公告)日：2012-04-10
申请号：US12742425
申请日：2008-11-13
申请人： Matthew Cox , Donogh John Roger O'Mahony , Maria De Los Angeles Estiarte-Martinez , Tadashi Kawashima , Satoshi Nagayama , Yuji Shishido , Hirotaka Tanaka , Matthew Alexander James Duncton , Andrew Antony Calabrese
发明人： Matthew Cox , Donogh John Roger O'Mahony , Maria De Los Angeles Estiarte-Martinez , Tadashi Kawashima , Satoshi Nagayama , Yuji Shishido , Hirotaka Tanaka , Matthew Alexander James Duncton , Andrew Antony Calabrese
IPC分类号： A01N43/42 , A61K31/44 , C07D471/02
CPC分类号： C07D215/48 , C07C311/08 , C07C2602/10 , C07D265/36 , C07D311/58 , C07D311/66 , C07D319/20 , C07D405/04
摘要： Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
摘要翻译： 公开了具有下列化学式的化合物：化合物可以制备成药物组合物，并且可以用于预防和治疗哺乳动物包括人的多种病症，包括作为非限制性实例的疼痛 ，炎症，创伤性损伤等。
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公开(公告)号：US08163901B2
公开(公告)日：2012-04-24
申请号：US12811972
申请日：2009-01-09
申请人： Matthew Duncton , Donogh John Roger O'Mahony , Matthew Cox , Maria De Los Angeles Estiarte-Martinez
发明人： Matthew Duncton , Donogh John Roger O'Mahony , Matthew Cox , Maria De Los Angeles Estiarte-Martinez
IPC分类号： C07D407/12 , C07D513/04 , C07D401/12 , C07D491/052 , C07D498/04 , A61K31/4709
CPC分类号： C07D405/12 , C07D401/12 , C07D498/04 , C07D513/04
摘要： Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
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公开(公告)号：US20110028465A1
公开(公告)日：2011-02-03
申请号：US12811972
申请日：2009-01-09
申请人： Matthew Duncton , Donogh John Roger O'Mahony , Matthew Cox , Maria De Los Angeles Estiarte-Martinez
发明人： Matthew Duncton , Donogh John Roger O'Mahony , Matthew Cox , Maria De Los Angeles Estiarte-Martinez
IPC分类号： A61K31/538 , C07D407/12 , C07D513/04 , C07D413/12 , C07D491/052 , C07D498/04 , C07D401/12 , A61K31/4709 , A61K31/416 , A61K31/437 , A61K31/436 , A61K31/5365 , A61P25/16 , A61P25/06 , A61P29/00 , A61P25/28 , A61P25/00 , A61P25/18 , A61P25/24 , A61P25/22 , A61P25/08 , A61P25/20 , A61P3/04 , A61P1/00 , A61P13/10 , A61P13/02 , A61P13/08 , A61P11/06 , A61P11/02 , A61P11/00 , A61P37/02 , A61P9/10 , A61P19/02 , A61P17/04 , A61P17/06 , A61P3/06 , A61P35/00 , A61P9/12 , A61P13/12
CPC分类号： C07D405/12 , C07D401/12 , C07D498/04 , C07D513/04
摘要： Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
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6.发明申请AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME 失效作为离子通道配体和药物组合物的酰胺衍生物及其使用方法公开(公告)号：US20110021514A1
公开(公告)日：2011-01-27
申请号：US12742425
申请日：2008-11-13
申请人： Matthew Cox , Donogh John Roger O'Mahony , Maria De Los Angeles Estiarte-Martinez , Tadashi Kawashima , Satoshi Nagayama , Yuji Shishido , Hirotaka Tanaka , Matthew Alexander James Duncton , Andrew Antony Calabrese
发明人： Matthew Cox , Donogh John Roger O'Mahony , Maria De Los Angeles Estiarte-Martinez , Tadashi Kawashima , Satoshi Nagayama , Yuji Shishido , Hirotaka Tanaka , Matthew Alexander James Duncton , Andrew Antony Calabrese
IPC分类号： A61K31/18 , C07D311/66 , A61K31/352 , C07C311/08 , C07D265/36 , A61K31/538 , C07D215/48 , A61K31/47 , C07D319/20 , A61K31/357 , C07D405/04 , A61K31/4709 , A61P29/00 , A61P37/06 , A61P13/10 , A61P3/00 , A61P9/00 , A61P35/00 , A61P19/00
CPC分类号： C07D215/48 , C07C311/08 , C07C2602/10 , C07D265/36 , C07D311/58 , C07D311/66 , C07D319/20 , C07D405/04
摘要： Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
摘要翻译： 公开了具有下列化学式的化合物：化合物可以制备成药物组合物，并且可以用于预防和治疗哺乳动物包括人的多种病症，包括作为非限制性实例的疼痛 ，炎症，创伤性损伤等。
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