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公开(公告)号：US5655660A
公开(公告)日：1997-08-12
申请号：US551904
申请日：1995-10-23
申请人： Lisa M. Dolin , Mark D. Allen
发明人： Lisa M. Dolin , Mark D. Allen
CPC分类号： B65D5/38 , B65D5/5028 , B65D77/26
摘要： A pharmaceutical distribution container is provided having a sleeve and a tray. The tray has four walls, also known as sidewall portions, each preferably of a trapezoidal configuration. At least a portion of the thickness of each of the opposed first and third sidewall portions is greater than the thickness of each of the opposed second and fourth sidewall portions. The sleeve has a top surface, a bottom surface and two end surfaces, each preferably of a rectangular configuration. A pharmaceutical retaining means is provided, with this component secured between opposing portions of the sidewall of the tray in respective recessed portions. Additionally, the pharmaceutical retaining means is formed having a rod with two end caps, one of which is preferably fixed while the other is preferably removable.
摘要翻译： 提供具有套筒和托盘的药物分配容器。 托盘具有四个壁，也称为侧壁部分，每个壁优选为梯形构型。 每个相对的第一和第三侧壁部分的厚度的至少一部分大于相对的第二和第四侧壁部分中的每一个的厚度。 套筒具有顶表面，底表面和两个端表面，每个优选地具有矩形构造。 提供了一种药物保持装置，该部件固定在托盘的侧壁的相对部分的相应的凹进部分中。 此外，药物保持装置形成有具有两个端盖的杆，其中一个优选是固定的，而另一个优选是可移除的。
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公开(公告)号：US20110094540A1
公开(公告)日：2011-04-28
申请号：US12899761
申请日：2010-10-07
申请人： Peter A. Morken , Karlheinz Hausmann , Keith Christian Andersen , Michael Joseph Molitor , Mark D. Allen , Thomas E. Lovelace
发明人： Peter A. Morken , Karlheinz Hausmann , Keith Christian Andersen , Michael Joseph Molitor , Mark D. Allen , Thomas E. Lovelace
CPC分类号： B29C45/1753 , B29C48/03 , B29C48/27
摘要： A method is provided for cleaning the interior of polymer processing equipment having a resin composition retained therein, wherein a contaminant material is adhered to at least a portion of the interior surface of the polymer processing equipment. The method comprises the steps of: charging the polymer processing equipment having a residual polymer composition retained in the interior thereof with a purging composition comprising 45-94 weight % of starch; 0.05 to 20 weight % of water; and (3) 5 to 45 weight % of polyol plasticizer, wherein the weight percentages of starch, water and polyol plasticizer are based on the total weight of starch, water and polyol plasticizer; operating the polymer processing equipment to i) convey the purging composition through the polymer processing equipment, thereby removing and withdrawing substantially all of the residual polymer composition from the polymer processing equipment and causing a portion of the purging composition to be retained as a residual purging composition within the interior of the polymer processing equipment; and ii) remove at least a portion of the contaminant material that is adhered to an interior surface of the polymer processing equipment; and removing the portion of the purging composition retained as a residual purging composition from within the interior of the polymer processing equipment.
摘要翻译： 提供了一种用于清洁其中保留有树脂组合物的聚合物加工设备的内部的方法，其中污染物质粘附到聚合物加工设备的内表面的至少一部分上。 该方法包括以下步骤：将含有残留聚合物组合物的聚合物加工设备装入含有45-94重量％淀粉的清洗组合物; 0.05至20重量％的水; 和（3）5〜45重量％的多元醇增塑剂，其中淀粉，水和多元醇增塑剂的重量百分比基于淀粉，水和多元醇增塑剂的总重量; 操作聚合物加工设备以i）通过聚合物加工设备输送清洗组合物，从而从聚合物加工设备中除去和排出基本上所有的残余聚合物组合物，并使一部分清洗组合物作为残留的清洗组合物保留 在聚合物加工设备的内部; 和ii）去除粘附到聚合物加工设备的内表面上的至少一部分污染物质; 以及从聚合物加工设备的内部除去作为残留吹扫组合物保留的清洗组合物的部分。
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公开(公告)号：US5641093A
公开(公告)日：1997-06-24
申请号：US546584
申请日：1995-10-23
申请人： Lisa M. Dolin , Mark D. Allen
发明人： Lisa M. Dolin , Mark D. Allen
CPC分类号： B65D5/5028 , B42F17/02
摘要： A method for assisting in the dispensing of pharmaceuticals is provided including the steps of: (1) determining what pharmaceutical needs to be restocked; (2) selecting a pharmaceutical distribution container corresponding to the pharmaceutical needing to be restocked, with the container including a tray and a sleeve. The tray has a base, a sidewall, and pharmaceutical retaining means within the tray, with such pharmaceutical retaining means including a rod, with the rod having a first and a second end and packets containing one each of the pharmaceutical needing to be restocked; (3) removing the tray from the sleeve; (4) removing the rod from the tray; and (5) transferring a predetermined number of packets from the rod to a restocking cart so the packets can be restocked.
摘要翻译： 提供了一种辅助药物分配的方法，包括以下步骤：（1）确定需要补充药物的药物; （2）选择与需要补充的药物对应的药物分配容器，容器包括托盘和套筒。 托盘在托盘内具有基部，侧壁和药物保持装置，其中这种药物保持装置包括杆，杆具有第一和第二端以及包含需要补充药物的每一个的包装; （3）从套筒中取出托盘; （4）从托盘中取出杆; 和（5）将预定数量的包从所述杆传送到补货车，使得所述包能被补充。
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4.发明授权Viscoelastic fluid for use in surgery and other therapies and method of using same 失效用于手术和其他疗法的粘弹性液体及其使用方法
公开(公告)号：US5068225A
公开(公告)日：1991-11-26
申请号：US565491
申请日：1990-08-10
CPC分类号： A61K9/0048 , A61F9/007 , A61L27/26 , A61L2430/16 , Y10S514/912 , Y10S514/915
摘要： This invention relates to an improved viscoelastic fluid or gel for use in surgery and other therapies which consists of polyethylene oxide in selected concentrations not to exceed approximately 15% (15,000 ppm), contained in a physiologic balanced salt solution. The PEO may also be used in conjunction with viscosity enhancers which also act as heat stabilizers such as methylcellulose and its derivatives, polyvinyl pyrrolidone of polyvinyl alcohol or in conjunction with elasticizes such as low molecular weight polyethylene glycols or polypropylene glycols or in conjunction with gelation modifiers. These mixtures may be modified to increase retention time in the body by crosslinking with the use of material like dimethyl urea. The invention encompasses the novel method of protecting and lubricating the corneal tissues during surgery with uses of different concentrations of the same solution introduced simultaneously to protect the inner cornea while periodically irrigating the outer cornea, all without obscuring the surgeon's view of the site. This invention also prevents the development of wound adhesion and has many utilizations in orthopedics.
摘要翻译： 本发明涉及用于手术和其它疗法的改进的粘弹性流体或凝胶，其由生理平衡盐溶液中所含的选定浓度不超过约15％（15,000ppm）的聚环氧乙烷组成。 PEO还可以与还可用作热稳定剂如甲基纤维素及其衍生物，聚乙烯醇的聚乙烯吡咯烷酮或与弹性化如低分子量聚乙二醇或聚丙二醇结合的粘度增强剂或与凝胶改性剂结合使用 。 可以通过使用诸如二甲基脲的材料进行交联来改变这些混合物以增加体内的保留时间。 本发明包括在手术过程中保护和润滑角膜组织的新方法，同时使用不同浓度的相同溶液来保护内角膜，同时周期性地冲洗外角膜，而不会使外科医生对该部位的视野模糊。 本发明还防止伤口粘连的发展，并且在骨科中具有许多应用。
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5.发明授权Viscoelastic fluid for use in spine and general surgery and other surgery and therapies and method of using same 失效用于脊柱和普通外科手术和其他手术和疗法的粘弹性液体及其使用方法
公开(公告)号：US5156839A
公开(公告)日：1992-10-20
申请号：US538232
申请日：1990-06-14
CPC分类号： A61K9/0048 , A61F9/007 , A61L27/26
摘要： This invention relates to an improved viscoelastic fluid or gel for use in general surgery and also more specifically in spine and neurosurgery and also in surgery dealing with reproductive organs. The invention encompasses the method of delivering to a surgical wound an implant composition having up to about a 21/2% by weight of carboxymethylcellulose (CMC) and at least about a 0.5% by weight polyethylene oxide (PEO) in a physiologically acceptable mixture.
摘要翻译： 本发明涉及一种用于一般手术的改进的粘弹性流体或凝胶，更具体地涉及脊柱和神经外科以及处理生殖器官的手术。 本发明包括向生理上可接受的混合物中向外科伤口递送具有高达约21/2重量％羧甲基纤维素（CMC）和至少约0.5重量％聚环氧乙烷（PEO））的植入物组合物的方法。
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6.发明授权Viscoelastic fluid for use in surgery and other therapies and method of using same 失效用于手术和其他疗法的粘弹性液体及其使用方法
公开(公告)号：US4983585A
公开(公告)日：1991-01-08
申请号：US266684
申请日：1988-11-03
CPC分类号： A61L27/18 , A61F9/007 , A61K31/77 , A61K9/0048 , A61L27/26 , A61L31/06 , A61L2430/16 , Y10S514/912 , Y10S514/915
摘要： This invention relates to an improved viscoelastic fluid or gel for use in surgery and other therapies which consists of polyethylene oxide in selected concentrations not to exceed approximately 15% (15,000 ppm), contained in a physiologic balanced salt solution. The PEO may also be used in conjunction with viscosity enhancers which also act as heat stabilizers such as methyl cellulose and its derivatives, polyvinyl pyrrolidone or polyvinyl, alcohol or in conjunction with elasticizers such as low molecular weight polyethylene glycols or polypropylene glycols or in conjunction with gelation modifiers. These mixtures may be modified to increase retention time in the body by crosslinking with the use of materials like dimethylol urea. The invention encompasses the novel method of protecting and lubricating the corneal tissues during surgery with uses of different concentrations of the same solution introduced simultaneously to protect the inner cornea while periodically irrigating the outer cornea, all without obscuring the surgeon's view of the site. This invention also prevents the development of wound adhesion and has many utilizations in orthopedics.
摘要翻译： 本发明涉及用于手术和其它疗法的改进的粘弹性流体或凝胶，其由生理平衡盐溶液中所含的选定浓度不超过约15％（15,000ppm）的聚环氧乙烷组成。 PEO也可以与还可用作热稳定剂如甲基纤维素及其衍生物，聚乙烯吡咯烷酮或聚乙烯醇，或与弹性剂如低分子量聚乙二醇或聚丙二醇结合使用的粘度增强剂，或与 凝胶改性剂。 这些混合物可以通过使用诸如二羟甲基脲之类的材料进行交联而被修饰以增加体内的保留时间。 本发明包括在手术过程中保护和润滑角膜组织的新方法，同时使用不同浓度的相同溶液来保护内角膜，同时周期性地冲洗外角膜，而不会使外科医生对该部位的视野模糊。 本发明还防止伤口粘连的发展，并且在骨科中具有许多应用。
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公开(公告)号：US4853374A
公开(公告)日：1989-08-01
申请号：US060013
申请日：1987-06-09
申请人： Mark D. Allen
发明人： Mark D. Allen
IPC分类号： A61K8/73 , A61K9/00 , A61K31/185 , A61K47/48 , A61Q17/04
CPC分类号： A61Q17/04 , A61K47/4823 , A61K8/731 , A61K9/0048 , A61K2800/57
摘要： This invention relates to a UV-blocked viscoelastic vitreous substitute for use in ophthalmic surgery comprising a hydroxy alkyl-substituted cellulose modified with a UV-absorbent molecule covalently bonded thereto having the type formula: ##STR1## where R.sup.1 is selected from the group consisting of H and OH; R.sup.2 is selected from the group consisting of H, OH or OR where R is any alkyl group; and, R.sup.3 is selected from the group consisting of H, SO.sub.3, OSO.sub.2 X where X is a leaving group.
摘要翻译： 本发明涉及一种用于眼科手术的紫外线封闭型粘弹性玻璃体替代物，其包含用共价键合的具有下式的其中的UV吸收分子改性的羟基烷基取代的纤维素：其中R 1选自 H和OH; R2选自H，OH或OR，其中R是任何烷基; 并且，R 3选自H，SO 3，OSO 2 X，其中X是离去基团。
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