公开(公告)号：US20120004322A1

公开(公告)日：2012-01-05

申请号：US13256552

申请日：2009-04-03

申请人： Yuko Matsui ,  Masanori Kamei ,  Kenkichi Sugiyama

发明人： Yuko Matsui ,  Masanori Kamei ,  Kenkichi Sugiyama

IPC分类号： A61K8/34 ,  C07C37/82 ,  A23L2/38 ,  A23L1/015 ,  A23L1/025 ,  C07C39/21 ,  A23L1/28

CPC分类号： A61K8/97 ,  A23L33/105 ,  A61K8/347 ,  A61K31/05 ,  A61K36/185 ,  A61Q19/02 ,  C07C37/82 ,  C07C39/21

摘要： Provided are a piceatannol-containing composition which is a composition originating in a natural material and containing piceatannol at a high concentration, and a method of producing the piceatannol-containing composition. A piceatannol-containing composition which contains 0.0001 to 99.9% by mass of piceatannol is obtained by extracting passion fruit seeds. The extraction of piceatannol is carried out by grinding the passion fruit seeds, adding at least one solvent selected from an aqueous alcohol-based solvent and an aqueous ketone-based solvent and agitating to thereby extract piceatannol into the above-described solvent. In this case, it is preferable to conduct stepwise extraction by using both of the aqueous alcohol-based solvent and the aqueous ketone-based solvent.

摘要翻译： 本发明提供一种含有起始天然物质并含有高浓度的吡草坦醇的组合物，以及含有该草甘膦的组合物的制造方法。 通过提取西番莲果实种子获得含有0.0001〜99.9质量％的云杉醇的含有吡草胺的组合物。 通过研磨西番莲籽，加入至少一种选自醇系溶剂水溶液和酮系溶剂的溶剂并进行搅拌，从而将吡哆醇提取到上述溶剂中来进行。 在这种情况下，优选通过使用含水醇类溶剂和酮系溶剂水溶液进行逐步提取。

公开(公告)号：US06488969B1

公开(公告)日：2002-12-03

申请号：US10153383

申请日：2002-05-22

申请人： Haruhiko Tsutsumi ,  Takashi Mato ,  Masanori Kamei ,  Shuichi Hashizume ,  Ryouichi Ito

发明人： Haruhiko Tsutsumi ,  Takashi Mato ,  Masanori Kamei ,  Shuichi Hashizume ,  Ryouichi Ito

IPC分类号： A61K3578

CPC分类号： A23G1/56 ,  A23K20/10 ,  A23L33/105 ,  A61K36/185 ,  A61K2300/00

摘要： A method for reducing the blood ammonia concentration in a human comprising administering to a human in need thereof a pharmaceutically effective amount of a cocoa component.

摘要翻译： 一种降低人血液中氨浓度的方法，包括向有需要的人施用药学上有效量的可可组分。

公开(公告)号：US5741652A

公开(公告)日：1998-04-21

申请号：US536740

申请日：1995-09-29

申请人： Akitaka Shibuya ,  Shunji Saitoh ,  Toshio Takahashi ,  Masanori Kamei ,  Naoko Maruo

发明人： Akitaka Shibuya ,  Shunji Saitoh ,  Toshio Takahashi ,  Masanori Kamei ,  Naoko Maruo

IPC分类号： G01N33/53 ,  C07K16/00 ,  C07K16/18 ,  C07K19/00 ,  C12N5/10 ,  C12N15/02 ,  C12P21/08 ,  G01N33/577 ,  G01N33/68

CPC分类号： C07K16/18 ,  G01N33/6887 ,  Y10S435/975

摘要： A method for one-step immunoassay of human type IV collagen, which uses a carrier immobilizing monoclonal antibody against human type IV collagen and a labelled polyclonal antibody against human type IV collagen, as well as a kit therefor and monoclonal antibodies which are particularly suited therefor. It is possible to accurately and quickly measure human type IV collagen in blood serum, for example, and obtain measurement results which accurately reflect pathological conditions.

摘要翻译： 使用针对人IV型胶原的针对人IV型胶原的载体固定化单克隆抗体和针对人IV型胶原的标记多克隆抗体的人IV型胶原的一步免疫测定方法及其特别适用的单克隆抗体 。 例如，可以准确，快速地测量血清中的IV型胶原，并获得准确反映病理状况的测定结果。

公开(公告)号：US20050239883A1

公开(公告)日：2005-10-27

申请号：US11107745

申请日：2005-04-18

申请人： Yumiko Tani ,  Tatsuo Watanabe ,  Masanori Kamei ,  Masatoshi Kato ,  Koji Yanae

发明人： Yumiko Tani ,  Tatsuo Watanabe ,  Masanori Kamei ,  Masatoshi Kato ,  Koji Yanae

IPC分类号： A23L1/30 ,  A61K31/222 ,  A61P1/16 ,  A61P3/06 ,  A61K31/22

CPC分类号： A61K31/222 ,  A23L33/105

摘要： A composition for lowering internal lipid in a subject which contains a capsinoid substance represented by the following formula wherein n is an integer from 0 to 10. Methods of using the compositions are disclosed and include administering to a subject in need of such treatment.

摘要翻译： 用于降低受试者内部脂质的组合物，其含有由下式表示的类毒素物质，其中n为0至10的整数。使用所述组合物的方法包括给予需要这种治疗的受试者。

公开(公告)号：US08617620B2

公开(公告)日：2013-12-31

申请号：US13256552

申请日：2009-04-03

申请人： Yuko Matsui ,  Masanori Kamei ,  Kenkichi Sugiyama

发明人： Yuko Matsui ,  Masanori Kamei ,  Kenkichi Sugiyama

IPC分类号： A61K36/00 ,  A23L1/00 ,  A23C3/00 ,  A23L2/38

CPC分类号： A61K8/97 ,  A23L33/105 ,  A61K8/347 ,  A61K31/05 ,  A61K36/185 ,  A61Q19/02 ,  C07C37/82 ,  C07C39/21

摘要： Provided are a piceatannol-containing composition which is a composition originating in a natural material and containing piceatannol at a high concentration, and a method of producing the piceatannol-containing composition. A piceatannol-containing composition which contains 0.0001 to 99.9% by mass of piceatannol is obtained by extracting passion fruit seeds. The extraction of piceatannol is carried out by grinding the passion fruit seeds, adding at least one solvent selected from an aqueous alcohol-based solvent and an aqueous ketone-based solvent and agitating to thereby extract piceatannol into the above-described solvent. In this case, it is preferable to conduct stepwise extraction by using both of the aqueous alcohol-based solvent and the aqueous ketone-based solvent.

摘要翻译： 本发明提供一种含有起始天然物质并含有高浓度的吡草坦醇的组合物，以及含有该草甘膦的组合物的制造方法。 通过提取西番莲果实种子获得含有0.0001〜99.9质量％的云杉醇的含有吡草胺的组合物。 通过研磨西番莲籽，加入至少一种选自醇系溶剂水溶液和酮系溶剂的溶剂并进行搅拌，从而将吡哆醇提取到上述溶剂中来进行。 在这种情况下，优选通过使用含水醇类溶剂和酮系溶剂水溶液进行逐步提取。

公开(公告)号：US4423428A

公开(公告)日：1983-12-27

申请号：US200781

申请日：1980-10-27

申请人： Shigeo Kuwabara ,  Masanori Kamei

发明人： Shigeo Kuwabara ,  Masanori Kamei

IPC分类号： B43L13/02 ,  G01D15/16 ,  B43L13/00

CPC分类号： G01D15/16 ,  B43L13/024

摘要： A pencil head for automatic pencil drawing is provided with an up-and-down moving mechanism for one of pencil leads held on a periphery of a holding turret and a mounting mechanism for the holding turret, the up-and-down moving mechanism comprising a spring for raising a resilient member grasping the pencil lead which slides through a tubular holder fixed in the periphery of the holding turret and a pushing stick for pushing down the pencil lead, which is supported by a slider sliding along a rail, and the mounting mechanism comprising a coupler projected coaxially from the holding turret with a stair-stepped male cross-section and a socket for engaging and rotating the coupler with a slitted stair-stepped female cross-section corresponding to the stair-stepped male cross-section of the coupler. Accordingly, high fidelity and quick response of the pencil head used for automatic pencil drawing and shortening of time duration required therefor can be realized.

摘要翻译： 用于自动铅笔绘图的铅笔头设置有用于保持在保持转台的周边上的铅笔引线之一和用于保持转台的安装机构的上下移动机构，该上下移动机构包括： 弹簧，用于升高抓住铅笔线的弹性构件，该铅笔线滑动通过固定在保持转塔周边的管状保持架，以及用于推下铅笔线的推杆，所述推杆由沿轨道滑动的滑块支撑;以及安装机构 包括一个与保持转台共同突出的耦合器，其具有阶梯式的阳性横截面，以及用于使耦合器接合和旋转的插座，该插座具有对应于耦合器的阶梯式阳性横截面 。 因此，可以实现用于自动铅笔绘制的铅笔头的高保真度和快速响应，并缩短其所需的时间。

公开(公告)号：US07414075B2

公开(公告)日：2008-08-19

申请号：US11107745

申请日：2005-04-18

申请人： Yumiko Tani ,  Tatsuo Watanabe ,  Masanori Kamei ,  Masatoshi Kato ,  Koji Yanae

发明人： Yumiko Tani ,  Tatsuo Watanabe ,  Masanori Kamei ,  Masatoshi Kato ,  Koji Yanae

IPC分类号： A61K31/22 ,  A61K31/23

CPC分类号： A61K31/222 ,  A23L33/105

摘要： A composition for lowering internal lipid in a subject which contains a capsinoid substance represented by the following formula wherein n is an integer from 0 to 10. Methods of using the compositions are disclosed and include administering to a subject in need of such treatment.

摘要翻译： 用于降低受试者内部脂质的组合物，其含有由下式表示的类毒素物质，其中n为0至10的整数。使用所述组合物的方法包括给予需要这种治疗的受试者。

公开(公告)号：US20050152852A1

公开(公告)日：2005-07-14

申请号：US10996427

申请日：2004-11-26

申请人： Eisaku Nishimura ,  Chinami Hirao ,  Tomoko Ohshima ,  Susumu Sato ,  Hiroyuki Inagaki ,  Masanori Kamei ,  Masatoshi Kato ,  Shuichi Hashiizume ,  Nobuko Maeda

发明人： Eisaku Nishimura ,  Chinami Hirao ,  Tomoko Ohshima ,  Susumu Sato ,  Hiroyuki Inagaki ,  Masanori Kamei ,  Masatoshi Kato ,  Shuichi Hashiizume ,  Nobuko Maeda

IPC分类号： A61K8/36 ,  A61K8/97 ,  A61K31/20 ,  A61K31/201 ,  A61K36/185 ,  A61K36/899 ,  A61K45/06 ,  A61Q11/00 ,  A61K7/28 ,  A61K35/78

CPC分类号： A61K8/97 ,  A61K8/361 ,  A61K31/20 ,  A61K31/201 ,  A61K36/185 ,  A61K36/899 ,  A61K45/06 ,  A61Q11/00 ,  A61K2300/00

摘要： It is intended to provide a composition against periodontal bacteria, which has a high safety without showing any side effects and exhibits an excellent effect of killing periodontal bacteria without affecting the growth of nonpathogenic indigenous microorganisms in the oral cavity, and foods, drinks and mouth washers against periodontal bacteria. A composition against periodontal bacteria is blended with a cocoa fraction contained in cacao mass, a hot water-extract of the cocoa fraction, polyphenols originating in the cocoa fraction or free fatty acids originating in the cocoa fraction as the active ingredient. Then the obtained composition against periodontal bacteria is added to foods, drinks, mouth washers or toothpaste. As well as the above-described cocoa fraction, a composition containing cacao mass and/or cocoa is instantly available for the composition against periodontal bacteria. It is preferable that the above-described free fatty acids contain at least one member selected from palmitic acid, stearic acid, oleic acid and linoleic acid.

摘要翻译： 旨在提供一种针对牙周细菌的组合物，其具有高安全性而不显示任何副作用，并且表现出极好的杀死牙周细菌的作用，而不影响口腔内非致病性土着微生物的生长，以及食品，饮料和口腔清洗机 针对牙周细菌。 将针对牙周细菌的组合物与可可块中可可级分，可可级分的热水提取物，源自可可级分的多酚或源自可可级分的游离脂肪酸作为活性成分共混。 然后将获得的针对牙周细菌的组合物加入到食品，饮料，口腔清洁剂或牙膏中。 除了上述可可级分之外，含有可可块和/或可可的组合物可立即获得针对牙周细菌的组合物。 上述游离脂肪酸优选含有选自棕榈酸，硬脂酸，油酸和亚油酸中的至少一种。