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1.
公开(公告)号:US20110160308A1
公开(公告)日:2011-06-30
申请号:US12375247
申请日:2007-07-27
IPC分类号: A61K31/165 , A61P27/02
CPC分类号: A61K31/165
摘要: Compositions and methods for treating disorders of the outer retina with compounds that inhibit monoamine oxidase are disclosed.
摘要翻译: 公开了用抑制单胺氧化酶的化合物治疗外部视网膜疾病的组合物和方法。
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公开(公告)号:US5948801A
公开(公告)日:1999-09-07
申请号:US36960
申请日:1998-03-09
申请人: Rupa Doshi , Michael A. Kapin
发明人: Rupa Doshi , Michael A. Kapin
IPC分类号: A61K31/542 , A61K31/41
CPC分类号: A61K31/542 , Y10S514/912
摘要: Methods for preventing and treating retinal edema with brinzolamide are disclosed.
摘要翻译: 公开了用布林佐胺预防和治疗视网膜水肿的方法。
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公开(公告)号:US5710165A
公开(公告)日:1998-01-20
申请号:US271290
申请日:1994-07-06
IPC分类号: A61K31/00 , A61K31/445 , A01N43/40
CPC分类号: A61K31/445 , A61K31/00 , Y10S514/913
摘要: Polyamine antagonists are found to be effective in preventing or reducing visual field loss associated with glaucoma. Especially preferred are certain 1-phenyl-2-piperidinoalkanol derivatives, such as eliprodil and ifenprodil.
摘要翻译: 发现多胺拮抗剂有效预防或减少与青光眼有关的视野丧失。 特别优选的是1-苯基-2-哌啶子基链烷醇衍生物,例如厄洛替丁和伊芬醌。
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4.
公开(公告)号:US5681854A
公开(公告)日:1997-10-28
申请号:US563315
申请日:1995-11-22
申请人: Iok-Hou Pang , Michael A. Kapin
发明人: Iok-Hou Pang , Michael A. Kapin
IPC分类号: A61K31/19
CPC分类号: A61K31/19 , Y10S514/912
摘要: The use of certain aliphatic carboxylic acid derivatives to treat persons suffering from retinal or optic nerve head damage is disclosed.
摘要翻译: 公开了使用某些脂族羧酸衍生物来治疗患有视网膜或视神经损伤的人。
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5.Use of cyclodextrins as an active ingredient for treating dry AMD and solubilizing drusen 有权
标题翻译: 使用环糊精作为治疗干性AMD和溶解玻璃疣的活性成分公开(公告)号:US08158609B1
公开(公告)日:2012-04-17
申请号:US11934132
申请日:2007-11-02
申请人: David Allen Marsh , Robert J. Collier, Jr. , Michael A. Kapin , Youqin Tian , Eliot Mark Slovin
发明人: David Allen Marsh , Robert J. Collier, Jr. , Michael A. Kapin , Youqin Tian , Eliot Mark Slovin
IPC分类号: A61K31/724
CPC分类号: A61K31/724 , A61K9/0048 , A61K47/40
摘要: The present invention is directed to the treatment of disorders involving the accumulation of drusen, such as dry age-related macular degeneration and geographic atrophy via administration of therapeutically effective amounts of at least one monomeric or polymeric cyclodextrin.
摘要翻译: 本发明涉及通过施用治疗有效量的至少一种单体或聚合物环糊精来治疗涉及玻璃疣累积的疾病,例如干年龄相关性黄斑变性和地理性萎缩。
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公开(公告)号:US07081482B2
公开(公告)日:2006-07-25
申请号:US10130408
申请日:2000-11-29
IPC分类号: A61K31/135
CPC分类号: A61K31/165 , A61K31/138 , A61K31/222 , A61K31/34 , A61K31/343 , A61K31/404 , A61K31/4704 , A61K31/5377 , Y10S514/912
摘要: The invention is directed to the use of β-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina.
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7.Use of Beta-Adrenoceptor Antagonists for the Manufacture of a Medicament for the Treatment of Disorders of the Outer Retina 失效
标题翻译: β-肾上腺素受体拮抗剂用于制造外视网膜疾病治疗药物的应用公开(公告)号:US20100249134A1
公开(公告)日:2010-09-30
申请号:US12796942
申请日:2010-06-09
IPC分类号: A61K31/5377 , A61K31/138 , A61K31/4704 , A61K31/22 , A61K31/343 , A61K31/405 , A61P27/02
CPC分类号: A61K31/165 , A61K31/138 , A61K31/222 , A61K31/34 , A61K31/343 , A61K31/404 , A61K31/4704 , A61K31/5377 , Y10S514/912
摘要: Compositions and methods for treating disorders of the outer retina with β-adrenoceptor antagonists are disclosed.
摘要翻译: 公开了用β-肾上腺素能受体拮抗剂治疗外部视网膜疾病的组合物和方法。
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8.COMPOUNDS WITH 5-HT1A ACTIVITY USEFUL FOR TREATING DISORDERS OF THE OUTER RETINA 审中-公开
标题翻译: 具有5-HT1A活性的化合物可用于治疗外周疾病公开(公告)号:US20100168121A1
公开(公告)日:2010-07-01
申请号:US12719152
申请日:2010-03-08
IPC分类号: A61K31/506 , A61K31/496 , A61K31/428 , A61K31/4418 , A61K31/438 , A61K31/4433 , A61K31/135 , A61P27/02
CPC分类号: A61K31/519 , A61K31/496 , A61K31/506 , Y10S514/912
摘要: Compositions and methods for treating disorders of the outer retina with compounds with 5-HT1A agonist activity are disclosed.
摘要翻译: 公开了用具有5-HT1A激动剂活性的化合物治疗外部视网膜疾病的组合物和方法。
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公开(公告)号:US06509355B1
公开(公告)日:2003-01-21
申请号:US09807805
申请日:2001-04-18
申请人: Robert J. Collier, Jr. , Mark R. Hellberg , Michael A. Kapin , George E. Barnes , Michael L. Chandler
发明人: Robert J. Collier, Jr. , Mark R. Hellberg , Michael A. Kapin , George E. Barnes , Michael L. Chandler
IPC分类号: A61K31445
CPC分类号: A61K31/00 , A61K31/445 , Y10S514/912
摘要: This invention is directed to the use of glutamate antagonists to treat the disorders of outer retina.
摘要翻译: 本发明涉及谷氨酸拮抗剂用于治疗外部视网膜疾病的用途。
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10.Use of certain isoquinolinesulfonyl compounds for the treatment of glaucoma and ocular ischemia 失效
标题翻译: 使用某些异喹啉磺酰化合物治疗青光眼和眼部缺血公开(公告)号:US06271224B1
公开(公告)日:2001-08-07
申请号:US09077575
申请日:1999-01-19
IPC分类号: A61K3155
CPC分类号: A61K31/497 , A61K9/0048 , A61K31/551 , Y10S514/912 , Y10S514/913
摘要: The present invention relates to the field of ophthalmology. In particular the invention relates to the field of ocular disorders including visual field loss and glaucoma using an isoquinolinesulfonyl compound, which lowers intraocular pressure (IOP) and produces dilation of ocular blood vessels.
摘要翻译: 本发明涉及眼科领域。 特别地,本发明涉及眼部疾病的领域,包括使用异喹啉磺酰化合物的视野丧失和青光眼,其降低眼内压(IOP)并产生眼血管扩张。
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