-
公开(公告)号：US07847932B2
公开(公告)日：2010-12-07
申请号：US11966279
申请日：2007-12-28
申请人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
发明人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
IPC分类号： G01J3/44
CPC分类号： G01N21/658 , G01N2021/651 , G01N2201/0221
摘要： Portable substance identification system and method are configured to identify at least one detection target faster and with greater accuracy than is possible using prior substance identification systems and/or prior substance identification techniques. An embodiment of the portable substance identification system includes a portable substance identification device containing a Raman spectrometer, and a collection stem that includes a collector. One or more reservoirs for a liquid medium and/or at least one reagent can be formed in the collection stem. The cartridge can include a chamber in which the reagents, liquid medium, and at least one detection target picked up by the collector are mixed. A magnet, positioned at a slant angle, can be used to form at least one pellet of aggregated magnetic particles within a pellet forming area of the chamber. The pellet is formed to maximize its surface area.
摘要翻译： 便携式物质识别系统和方法配置成比使用先前物质识别系统和/或先前物质识别技术更快，更准确地识别至少一个检测目标。 便携式物质识别系统的实施例包括包含拉曼光谱仪的便携式物质识别装置和包括收集器的收集杆。 用于液体介质和/或至少一种试剂的一个或多个储存器可以形成在收集杆中。 药筒可以包括其中混合有由试剂，液体介质和由收集器拾取的至少一个检测目标的室。 以倾斜角定位的磁体可以用于在腔室的颗粒形成区域内形成至少一个聚集的磁性颗粒颗粒。 形成颗粒使其表面积最大化。
-
公开(公告)号：US20090168592A1
公开(公告)日：2009-07-02
申请号：US11966395
申请日：2007-12-28
申请人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
发明人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
IPC分类号： B01F13/00
CPC分类号： B01F15/0205 , B01F13/002 , B01F15/0206 , B01F15/0226 , G01N35/0098 , G01N2035/00465
摘要： A substance identification system is configured to identify at least one detection target faster and with greater accuracy than is possible using prior substance identification systems and/or prior substance identification techniques. An agitator for a portable substance identification system includes a body. The body has a receptacle formed therein. The receptacle is configured to receive a cartridge. The cartridge has a chamber formed therein and a collector of a collection stem coupled with the chamber.
摘要翻译： 物质识别系统配置成比使用先前物质识别系统和/或先前物质识别技术更快，更准确地识别至少一个检测目标。 用于便携式物质识别系统的搅拌器包括主体。 本体具有形成在其中的容器。 容器被配置成接收盒。 盒具有形成在其中的腔室和与腔室联接的收集杆的收集器。
-
公开(公告)号：US20090168058A1
公开(公告)日：2009-07-02
申请号：US11966279
申请日：2007-12-28
申请人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
发明人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
IPC分类号： G01J3/44
CPC分类号： G01N21/658 , G01N2021/651 , G01N2201/0221
摘要： Portable substance identification system and method are configured to identify at least one detection target faster and with greater accuracy than is possible using prior substance identification systems and/or prior substance identification techniques. An embodiment of the portable substance identification system includes a portable substance identification device containing a Raman spectrometer, and a collection stem that includes a collector. One or more reservoirs for a liquid medium and/or at least one reagent can be formed in the collection stem. The cartridge can include a chamber in which the reagents, liquid medium, and at least one detection target picked up by the collector are mixed. A magnet, positioned at a slant angle, can be used to form at least one pellet of aggregated magnetic particles within a pellet forming area of the chamber. The pellet is formed to maximize its surface area.
摘要翻译： 便携式物质识别系统和方法配置成比使用先前物质识别系统和/或先前物质识别技术更快，更准确地识别至少一个检测目标。 便携式物质识别系统的实施例包括包含拉曼光谱仪的便携式物质识别装置和包括收集器的收集杆。 用于液体介质和/或至少一种试剂的一个或多个储存器可以形成在收集杆中。 药筒可以包括其中混合有由试剂，液体介质和由收集器拾取的至少一个检测目标的室。 以倾斜角定位的磁体可以用于在腔室的颗粒形成区域内形成至少一个聚集的磁性颗粒颗粒。 形成颗粒使其表面积最大化。
-
公开(公告)号：US20090168052A1
公开(公告)日：2009-07-02
申请号：US11966332
申请日：2007-12-28
申请人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
发明人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
IPC分类号： G01N1/00
CPC分类号： G01N21/65 , G01N1/405 , G01N21/658
摘要： A portable substance identification system and method are configured to identify at least one detection target faster and with greater accuracy than is possible using prior substance identification systems and/or prior substance identification techniques. An embodiment of the portable substance identification system includes a portable substance identification device containing a Raman spectrometer, and a collection stem that includes a dry collector. One or more reservoirs for a liquid medium and /or a reagent can be formed in a cartridge that is configured to couple with a portable substance identification device. The cartridge has a chamber in which the reagent, liquid medium, and a detection target picked up by the dry collector are mixed. A magnet, positioned at a slant angle, can be used to form at least one pellet of aggregated magnetic particles within a pellet forming area of the chamber. The pellet is formed to maximize its surface area.
摘要翻译： 便携式物质识别系统和方法被配置为比使用先前物质识别系统和/或先前物质识别技术更快，更准确地识别至少一个检测目标。 便携式物质识别系统的实施例包括含有拉曼光谱仪的便携式物质识别装置和包括干燥收集器的收集杆。 用于液体介质和/或试剂的一个或多个储存器可以形成在配置成与便携式物质识别装置联接的盒中。 该盒具有混合由干燥收集器拾取的试剂，液体介质和检测对象的室。 以倾斜角定位的磁体可以用于在腔室的颗粒形成区域内形成至少一个聚集的磁性颗粒颗粒。 形成颗粒使其表面积最大化。
-
公开(公告)号：US07518721B2
公开(公告)日：2009-04-14
申请号：US11223353
申请日：2005-09-09
申请人： Michael Craig Burrell , Frank J. Mondello , Yuan-Hsiang Lee , Patrick Ronald Engel , Andrew David Pris
发明人： Michael Craig Burrell , Frank J. Mondello , Yuan-Hsiang Lee , Patrick Ronald Engel , Andrew David Pris
IPC分类号： G01J3/44
CPC分类号： G01N21/65 , G01N21/658
摘要： A lateral flow device is disclosed. The lateral flow device includes a substrate having a flow path and a detection zone disposed along the flow path. The detection zone includes an immobilized target-binding moiety directed against a target of a Raman-active complex. Also disclosed is a method of conducting a lateral flow assay and detection system. The method includes i) defining a flow path having a detection zone; ii) flowing a sample down the flow path; and iii) immobilizing a Raman-active complex if present, at the detection zone. The sample includes a Raman-active complex or a Raman-active tag.
摘要翻译： 公开了一种侧流装置。 横向流动装置包括具有沿着流动路径设置的流路和检测区域的基板。 检测区包括针对拉曼活性复合物的靶的固定的靶结合部分。 还公开了进行侧流测定和检测系统的方法。 该方法包括：i）定义具有检测区域的流路; ii）将样品沿着流动路径流动; 和iii）在检测区域固定拉曼活性复合物（如果存在）。 样品包括拉曼活性复合物或拉曼活性标签。
-
公开(公告)号：US06733840B2
公开(公告)日：2004-05-11
申请号：US10162394
申请日：2002-06-05
申请人： Christopher Michael Byrne , Matthew David Butts , Kathryn Ann Shaffer , Steven James Stoessel , Michael Craig Burrell
发明人： Christopher Michael Byrne , Matthew David Butts , Kathryn Ann Shaffer , Steven James Stoessel , Michael Craig Burrell
IPC分类号： B05D302
CPC分类号： D06M15/643
摘要： A method for treating a cellulose-containing substrate is provided in the present invention, the method comprising contacting a silicone composition comprising at least one polysiloxane or silicone resin containing at least one functional group comprising at least one dialkylacetal group, at least one anhydride group, at least one reactive group, or combinations thereof with the cellulose-containing substrate; and curing the silicone composition on the cellulose-containing substrate at a temperature in a range between about 25° C. and about 200° C. A further embodiment of the present invention includes a formulation containing the aforementioned silicone composition.
摘要翻译： 在本发明中提供了一种处理含纤维素基质的方法，该方法包括将包含至少一种聚硅氧烷或含有至少一个包含至少一个二烷基缩醛基官能团的硅氧烷树脂的硅氧烷组合物，至少一种酸酐基团， 至少一种反应性基团或其与含纤维素的基质的组合; 并且在约25℃至约200℃的温度范围内使含纤维素的基材上的硅氧烷组合物固化。本发明的另一个实施方案包括含有上述有机硅组合物的制剂。
-
公开(公告)号：US20100279272A1
公开(公告)日：2010-11-04
申请号：US12030609
申请日：2008-02-13
申请人： Michael Craig Burrell , John Yupeng Gui , Frank John Mondello , Andrew David Pris , Tracy Lynn Paxon
发明人： Michael Craig Burrell , John Yupeng Gui , Frank John Mondello , Andrew David Pris , Tracy Lynn Paxon
CPC分类号： G01N33/54373 , G01N21/658 , Y10T436/143333
摘要： Methods are described for performing a multiplexed analysis of a level of target analyte in a sample, employing an identifier and a labeling reagent. Either or both of the identifier and the labeling reagent comprises a SERS-active nanoparticle associated with a SERS-active reporter with a uniquely identifiable spectroscopic signature. Interrogation of the identifier and the labeling reagent is conducted by serial coincident detection. Such methods can provide enhanced multiplexed analysis of analytes in a sample, especially with regards to improving the type of identifying reagents that are employed.
摘要翻译： 描述了使用标识符和标记试剂进行样品中目标分析物水平的多重分析的方法。 标识符和标记试剂中的任一个或两者包含与具有唯一可识别的光谱特征的SERS-活性报道分子相关联的SERS活性纳米颗粒。 标识符和标记试剂的询问通过串行重合检测进行。 这样的方法可以提供样品中分析物的增强的多重分析，特别是关于改进所采用的鉴定试剂的类型。
-
公开(公告)号：US20090169433A1
公开(公告)日：2009-07-02
申请号：US11966378
申请日：2007-12-28
申请人： Sankaran Kumar , Christopher Crowley , Erik Edmund Magnuson , Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon
发明人： Sankaran Kumar , Christopher Crowley , Erik Edmund Magnuson , Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon
IPC分类号： G01N21/31
CPC分类号： G01N21/658 , G01N2021/651
摘要： A substance identification system is configured to identify at least one detection target faster and with greater accuracy than is possible using prior substance identification systems and/or prior substance identification techniques. A chamber includes a pellet forming area having a predetermined geometry that is configured to maximize a ratio of a pellet surface area to a pellet volume. A magnet is positioned on one side of the chamber and configured to form a pellet of aggregated magnetic particles in the pellet forming area. A laser source is positioned on the same side of the chamber as the magnet and configured to illuminate the pellet, when the pellet is formed in the pellet forming area.
摘要翻译： 物质识别系统配置成比使用先前物质识别系统和/或先前物质识别技术更快，更准确地识别至少一个检测目标。 腔室包括具有预定几何形状的丸粒形成区域，其被构造成使球团表面积与球团体积的比例最大化。 磁体位于室的一侧，并且构造成在颗粒形成区域中形成聚集的磁性颗粒的颗粒。 当颗粒形成在颗粒形成区域中时，激光源被定位在与磁体相同的腔室的相同侧上并被配置为照射颗粒。
-
公开(公告)号：US08440469B2
公开(公告)日：2013-05-14
申请号：US11764537
申请日：2007-06-18
IPC分类号： G01N33/553 , G01N33/543
CPC分类号： G01N21/6428 , G01N33/54333
摘要： A method for increasing a spectroscopic signal in a biological assay is provided. The method includes forming a suspension of magnetically attractable particles. The method also includes introducing a first magnetic field at a first location to draw the magnetically attractable particles towards the first location and form a first agglomeration. The method also includes removing the first magnetic field. The method further includes introducing a second magnetic field at a second location to draw the first agglomeration towards the second location and form a second agglomeration. The method further includes focusing an excitation source on the second agglomeration formed at the second location.
摘要翻译： 提供了用于增加生物测定中的光谱信号的方法。 该方法包括形成磁吸引颗粒的悬浮液。 该方法还包括在第一位置引入第一磁场以将磁性可吸引颗粒吸引到第一位置并形成第一附聚。 该方法还包括去除第一磁场。 该方法还包括在第二位置引入第二磁场以将第一附聚物吸引到第二位置并形成第二聚集。 该方法还包括将激发源聚焦在形成在第二位置处的第二聚集体上。
-
公开(公告)号：US07852470B2
公开(公告)日：2010-12-14
申请号：US11966332
申请日：2007-12-28
申请人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
发明人： Michael Craig Burrell , Frank Mondello , Tracy Lynn Paxon , William Scott Sutherland , Christopher Montalbano , Gregory Montalbano , Aaron Klein
IPC分类号： G01J3/44
CPC分类号： G01N21/65 , G01N1/405 , G01N21/658
摘要： A portable substance identification system and method are configured to identify at least one detection target faster and with greater accuracy than is possible using prior substance identification systems and/or prior substance identification techniques. An embodiment of the portable substance identification system includes a portable substance identification device containing a Raman spectrometer, and a collection stem that includes a dry collector. One or more reservoirs for a liquid medium and/or a reagent can be formed in a cartridge that is configured to couple with a portable substance identification device. The cartridge has a chamber in which the reagent, liquid medium, and a detection target picked up by the dry collector are mixed. A magnet, positioned at a slant angle, can be used to form at least one pellet of aggregated magnetic particles within a pellet forming area of the chamber. The pellet is formed to maximize its surface area.
摘要翻译： 便携式物质识别系统和方法被配置为比使用先前物质识别系统和/或先前物质识别技术更快，更准确地识别至少一个检测目标。 便携式物质识别系统的实施例包括含有拉曼光谱仪的便携式物质识别装置和包括干燥收集器的收集杆。 用于液体介质和/或试剂的一个或多个储存器可以形成在配置成与便携式物质识别装置联接的盒中。 该盒具有混合由干燥收集器拾取的试剂，液体介质和检测对象的室。 以倾斜角定位的磁体可以用于在腔室的颗粒形成区域内形成至少一个聚集的磁性颗粒颗粒。 形成颗粒使其表面积最大化。
-
-
-
-
-
-
-
-
-
搜索结果
12 条记录 (耗时 0.014 秒)
