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30 条记录 (耗时 0.052 秒)

    Hydrophilic polymeric coatings for medical articles
    2.
    发明授权
    Hydrophilic polymeric coatings for medical articles 有权
    用于医疗用品的亲水性聚合物涂层

    公开(公告)号：US07691476B2

    公开(公告)日：2010-04-06

    申请号：US11445806

    申请日：2006-06-02

    申请人： Michael J. Finley

    发明人： Michael J. Finley

    IPC分类号： B32B9/04

    CPC分类号： A61L29/085 ,  A61L29/14 ,  A61L2400/10 ,  C09D5/00 ,  Y10T428/31504 ,  Y10T428/31551

    摘要： The invention provides a durable, lubricious coating for a medical article that can be prepared from a first polymer that is synthetic, soluble in a polar liquid, and having first reactive groups, and a second polymer that is synthetic, hydrophilic, and that includes second reactive groups. The first reactive groups and a portion of the second reactive groups react to bond the first polymer to the second polymer. A portion of the second reactive groups remains unbonded which, upon neutralization, provide lubricious properties to the coating. In some aspects the coating is formed using a crosslinking agent having latent reactive groups. The coatings provide particularly long dry out times and are very useful for catheterization processes. In addition, the coatings can be subject to sterilization with ethylene oxide and retain very good durable and lubricious properties.

    摘要翻译： 本发明提供了一种用于医疗制品的耐久，润滑的涂层，其可以由合成的，可溶于极性液体的第一聚合物制备并具有第一反应性基团的第一聚合物，以及合成，亲水的第二聚合物，并且包括第二聚合物 反应性基团。 第一反应性基团和一部分第二反应性基团使第一聚合物与第二聚合物结合。 第二反应性基团的一部分保持未结合，其在中和时向涂层提供润滑性质。 在一些方面，使用具有潜在反应性基团的交联剂形成涂层。 涂层提供特别长的干燥时间，并且对于导尿过程非常有用。 此外，涂层可以与环氧乙烷进行灭菌，并保持非常好的持久和润滑性能。

    Low friction particulate coatings
    4.
    发明申请
    Low friction particulate coatings 审中-公开
    低摩擦颗粒涂层

    公开(公告)号：US20080057298A1

    公开(公告)日：2008-03-06

    申请号：US11512022

    申请日：2006-08-29

    申请人： Michael J. Finley

    发明人： Michael J. Finley

    IPC分类号： B32B5/16 ,  B32B15/04 ,  A61L33/00 ,  B05D1/12 ,  G11B5/64

    CPC分类号： A61L29/085 ,  A61L31/10 ,  Y10T428/254 ,  Y10T428/265 ,  Y10T428/31504 ,  Y10T428/31678 ,  C08L27/18

    摘要： The invention provides a low-friction halogenated nano- or microparticulate coating and method for forming the coating on articles, such as implantable medical articles. The halogenated nano- or microparticles, desirably fabricated from PTFE, are present on the surface of the coating and covalently coupled to a coupling component, which facilitates formation of the coating. The coatings are biocompatible and can be formed on a selected portion of a medical device in a straightforward process. In some aspects the nano- or microparticulate coatings are formed on a system for the insertion of a medical device, wherein the system includes a catheter.

    摘要翻译： 本发明提供了低摩擦卤化纳米或微粒涂层和用于在诸如可植入医疗制品的物品上形成涂层的方法。 期望由PTFE制成的卤化纳米颗粒或微粒存在于涂层的表面上并且共价偶联到偶联组分上，这有利于涂层的形成。 涂层是生物相容的并且可以在简单的过程中形成在医疗装置的选定部分上。 在一些方面，纳米或微粒涂层形成在用于插入医疗装置的系统上，其中该系统包括导管。

    Luer activated thread coupler
    6.
    发明授权
    Luer activated thread coupler 失效

    公开(公告)号：US06595964B2

    公开(公告)日：2003-07-22

    申请号：US09748580

    申请日：2000-12-22

    申请人： Michael J. Finley ,  Mark Williamson

    发明人： Michael J. Finley ,  Mark Williamson

    IPC分类号： A61M5178

    CPC分类号： A61M39/045 ,  A61M39/10 ,  A61M39/26 ,  A61M2039/0036 ,  A61M2039/1033 ,  A61M2039/1072 ,  Y10S604/905

    摘要： A coupler for receiving a threaded male luer fitting in sealed relationship includes a housing having an attachment end, a conduit end opposite the attachment end and defining a central passageway for providing fluid communication between the luer fitting and a conduit. An arrangement is attached to the housing for establishing a sealed connection between a luer tip and the central passageway. The conduit end has a relatively larger diameter than the attachment end and defines a shoulder at a junction of the attachment end and the conduit end. A resilient member is disposed on the attachment end adjacent the shoulder for exerting an axially directed compressive force upon the male luer fitting as it is threadably engaged upon the attachment end.

    Pre-slit injection site and tapered cannula
    7.
    发明授权
    Pre-slit injection site and tapered cannula 失效
    预切口注射部位和锥形插管

    公开(公告)号：US06569125B2

    公开(公告)日：2003-05-27

    申请号：US09907234

    申请日：2001-07-17

    申请人： Steven C. Jepson ,  Thomas E. Dudar ,  Michael J. Finley ,  Vincent C. Desecki

    发明人： Steven C. Jepson ,  Thomas E. Dudar ,  Michael J. Finley ,  Vincent C. Desecki

    IPC分类号： A61M528

    CPC分类号： A61J1/2089 ,  A61J1/10 ,  A61J1/1406 ,  A61J1/1475 ,  A61J1/201 ,  A61J1/2055 ,  A61J1/2096 ,  A61M5/162 ,  A61M39/045 ,  A61M39/1011 ,  A61M39/14 ,  A61M2039/1033 ,  A61M2039/1066 ,  A61M2039/1072 ,  A61M2205/195 ,  A61M2205/197 ,  Y10S604/905

    摘要： A pre-slit injection site (34) includes a housing (40) with a flow path therethrough. A first end (42) of the housing (40) carries a pre-slit septum (52). One form of a blunt cannula (98), usable with the injection site (34), carries a locking member (100). When the pre-slit injection site (34) slidably receives the blunt cannula (98), the locking member (100) latches to the injection site (34) and creates a mechanically coupled unit. Another form of the cannula (280) includes a tube having a tapered distal end region (298) and having elongate discharge slots (294) for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post (330), an annular barb (394), and axially oriented grooves (268).

    摘要翻译： 预狭缝注射部位（34）包括具有穿过其中的流动通道的壳体（40）。 壳体（40）的第一端（42）承载预切口隔膜（52）。 可与注射部位（34）一起使用的钝性插管（98）的一种形式承载锁定构件（100）。 当预狭缝注射部位（34）可滑动地接收钝头套管（98）时，锁定构件（100）锁定到注射部位（34）并产生机械耦合单元。 套管（280）的另一种形式包括具有锥形远端区域（298）并且具有细长的排出槽（294）的管子，用于减少接触表面积并将流体横向导引出套管。 插管还可以包括圆形引导柱（330），环形倒钩（394）和轴向定向的凹槽（268）。

    Hydrophilic polymeric coatings for medical articles
    10.
    发明授权
    Hydrophilic polymeric coatings for medical articles 有权
    用于医疗用品的亲水性聚合物涂层

    公开(公告)号：US08163327B2

    公开(公告)日：2012-04-24

    申请号：US12753613

    申请日：2010-04-02

    申请人： Michael J. Finley

    发明人： Michael J. Finley

    IPC分类号： B05D3/10 ,  B05D1/36 ,  A61M25/00 ,  B32B27/00

    CPC分类号： A61L29/085 ,  A61L29/14 ,  A61L2400/10 ,  C09D5/00 ,  Y10T428/31504 ,  Y10T428/31551

    摘要： The invention provides a durable, lubricious coating for a medical article that can be prepared from a first polymer that is synthetic, soluble in a polar liquid, and having first reactive groups, and a second polymer that is synthetic, hydrophilic, and that includes second reactive groups. The first reactive groups and a portion of the second reactive groups react to bond the first polymer to the second polymer. A portion of the second reactive groups remains unbonded which, upon neutralization, provide lubricious properties to the coating. In some aspects the coating is formed using a crosslinking agent having latent reactive groups. The coatings provide particularly long dry out times and are very useful for catheterization processes. In addition, the coatings can be subject to sterilization with ethylene oxide and retain very good durable and lubricious properties.

    摘要翻译： 本发明提供了一种用于医疗制品的耐久，润滑的涂层，其可以由合成的，可溶于极性液体的第一聚合物制备并具有第一反应性基团的第一聚合物，以及合成的，亲水的第二聚合物，并且包括第二聚合物 反应性基团。 第一反应性基团和一部分第二反应性基团使第一聚合物与第二聚合物结合。 第二反应性基团的一部分保持未结合，其在中和时向涂层提供润滑性质。 在一些方面，使用具有潜在反应性基团的交联剂形成涂层。 涂层提供特别长的干燥时间，并且对于导尿过程非常有用。 此外，涂层可以与环氧乙烷进行灭菌，并保持非常好的持久和润滑性能。