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公开(公告)号:US08820324B2
公开(公告)日:2014-09-02
申请号:US12304900
申请日:2007-06-13
CPC分类号: A61M15/0028 , A61M15/0008 , A61M15/002 , A61M15/0021 , A61M15/0036 , A61M15/0043 , A61M15/0045 , A61M2202/062 , A61M2202/064 , A61M2205/195 , A61M2205/197 , A61M2206/16 , A61M2209/06
摘要: A dry powder inhaler comprises two parts (2, 4) connected by an integrally molded, e.g. living hinge (6), so as to be moveable from an open position to a closed position. At least one of the parts (2, 4) defines at least part of a circulating airflow chamber (12), wherein when said parts (2, 4) are in said closed position, the inhaler comprises an airflow path including the circulating airflow chamber (12).
摘要翻译: 一种干粉吸入器包括通过整体模制的例如连接的两个部分(2,4)。 活动铰链(6),以便能够从打开位置移动到关闭位置。 所述部件(2,4)中的至少一个限定了循环气流室(12)的至少一部分,其中当所述部件(2,4)处于所述关闭位置时,所述吸入器包括气流路径,所述气流路径包括所述循环气流室 (12)。
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公开(公告)号:US08622965B2
公开(公告)日:2014-01-07
申请号:US12455645
申请日:2009-06-03
申请人: Marshall S. Kriesel
发明人: Marshall S. Kriesel
CPC分类号: A61M5/1407 , A61M5/1413 , A61M5/1454 , A61M5/16804 , A61M5/16881 , A61M39/18 , A61M2205/197 , A61M2205/583
摘要: A dispensing device for dispensing first and second medicaments to a patient that is made up of first and second stand-alone, interconnectable assemblies. The first of these assemblies comprises a fluid reservoir assembly that houses a fluid reservoir defining component while the second assembly comprises a fluid delivery and control assembly that includes an adding assembly for controllably dispensing the second medicament to the patient, a novel flow control means that functions to control the flow of medicinal fluid from the fluid reservoir of the first assembly toward the patient via a plurality of fluid flow control passageways. Because the stand-alone fluid delivery and control assembly is initially totally separate from the fluid reservoir assembly of the apparatus, the fluid flow passageways of the fluid delivery and control assembly can be effectively sterilized using conventional gamma ray sterilization techniques without adversely affecting the medicament contained within the fluid reservoir of the apparatus.
摘要翻译: 一种用于将第一和第二药物分配给由第一和第二独立的可互连组件构成的患者的分配装置。 这些组件中的第一个包括容纳流体储存器限定部件的流体储存器组件,而第二组件包括流体递送和控制组件,流体输送和控制组件包括用于将第二药剂可控地分配给患者的添加组件, 以经由多个流体流动控制通道来控制药液从第一组件的流体储存器朝向患者的流动。 由于独立的流体输送和控制组件最初与设备的流体储存器组件完全分离,流体输送和控制组件的流体流动通道可以使用常规的γ射线消毒技术被有效地消毒,而不会对包含的药物产生不利影响 在设备的流体储存器内。
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公开(公告)号:US06261266B1
公开(公告)日:2001-07-17
申请号:US09181975
申请日:1998-10-29
IPC分类号: A61M528
CPC分类号: A61J1/2089 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2055 , A61J1/2096 , A61M5/162 , A61M39/045 , A61M39/1011 , A61M39/14 , A61M2039/1033 , A61M2039/1066 , A61M2039/1072 , A61M2205/195 , A61M2205/197 , Y10S604/905
摘要: A pre-slit injection site (34) includes a housing (40) with a flow path therethrough. A first end (42) of the housing (40) carries a pre-slit septum (52). One form of a blunt cannula (98), usable with the injection site (34), carries a locking member (100). When the pre-slit injection site (34) slidably receives the blunt cannula (98), the locking member (100) latches to the injection site (34) and creates a mechanically coupled unit. Another form of the cannula (280) includes a tube having a tapered distal end region (298) and having elongate discharge slots (294) for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post (330), an annular barb (394), and axially oriented grooves (268).
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公开(公告)号:US06217568B1
公开(公告)日:2001-04-17
申请号:US08440510
申请日:1995-05-12
申请人: Steven C. Jepson , Thomas E. Dudar
发明人: Steven C. Jepson , Thomas E. Dudar
IPC分类号: A61M500
CPC分类号: A61J1/2089 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2055 , A61J1/2096 , A61M5/162 , A61M39/045 , A61M39/1011 , A61M39/14 , A61M2039/1033 , A61M2039/1066 , A61M2039/1072 , A61M2205/195 , A61M2205/197 , Y10S604/905
摘要: In a fluid sampling system, a pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. One form of a blunt cannula, usable with the injection site, carries a locking member. When the pre-slit injection site slidably receives the blunt cannula, the locking member latches to the injection site and creates a mechanically coupled unit. Another form of the cannula includes an elongated member having a tapered distal end region and a substantially cylindrical sheath surrounding the elongated member to protect it from inadvertent touch contamination. The sheath may include means defining at least two slots opposite one another at its distal end and the sheath may be outwardly tapered.
摘要翻译: 在流体采样系统中,预狭缝注射部位包括具有穿过其中的流动路径的壳体。 外壳的第一端装有预狭缝隔膜。 与注射部位一起使用的钝性插管的一种形式携带锁定构件。 当预狭缝注射部位可滑动地接收钝头套管时,锁定构件锁定到注射部位并产生机械耦合单元。 套管的另一种形式包括细长构件,其具有锥形远端区域和围绕细长构件的基本上圆柱形的护套,以保护其免于无意的触摸污染。 护套可以包括限定在其远端处彼此相对的至少两个槽的装置,并且护套可以向外锥形。
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公开(公告)号:US5921962A
公开(公告)日:1999-07-13
申请号:US991122
申请日:1997-12-16
申请人: Marshall S. Kriesel , Farhad Kazemzadeh , Matthew B. Kriesel , William W. Feng , Steve C. Barber , William J. Kluck
发明人: Marshall S. Kriesel , Farhad Kazemzadeh , Matthew B. Kriesel , William W. Feng , Steve C. Barber , William J. Kluck
CPC分类号: A61M5/158 , A61M31/002 , A61M5/152 , A61M2005/14513 , A61M2005/1581 , A61M2205/197 , A61M2209/045 , A61M5/14248 , Y10S128/12
摘要: A fluid delivery device for infusing medicinal fluids having a self-contained stored energy membrane for expelling fluids at a precisely controlled rate. The device is of a compact, low profile, laminate construction so that it can conveniently be used for the fluids, such as insulin and the like, into an ambulatory patient at controlled rates over extended periods of time. Included within the device are various fluid flow control elements including a unique hydraulic fluid rate control system for ultra low flow delivery. Also included is a highly novel flow indictor for providing a positive indication of fluid flow from the device and for indicating at any given time the amount of fluid remaining in the device.
摘要翻译: 一种流体输送装置,用于输注具有独立储存能量膜的药液,以精确控制的速率排出流体。 该装置具有紧凑,薄型的层压结构,使得其可以方便地用于诸如胰岛素等的流体,并且在长时间段内以受控的速率进入流动患者。 包括在装置内的是各种流体流量控制元件,包括用于超低流量输送的独特的液压流体速率控制系统。 还包括一种高度新颖的流量指示器,用于提供来自装置的流体流动的积极指示,并且用于在任何给定时间指示剩余在装置中的流体量。
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公开(公告)号:US5899888A
公开(公告)日:1999-05-04
申请号:US695040
申请日:1996-08-09
IPC分类号: A61B5/15 , A61B5/153 , A61J1/00 , A61J1/05 , A61J1/10 , A61J1/14 , A61J1/20 , A61M5/162 , A61M5/32 , A61M25/00 , A61M37/00 , A61M39/00 , A61M39/02 , A61M39/04 , A61M39/14 , A61M5/24
CPC分类号: A61J1/2089 , A61J1/2096 , A61M39/045 , A61M39/1011 , A61M39/14 , A61M5/162 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2055 , A61M2039/1033 , A61M2039/1066 , A61M2039/1072 , A61M2205/195 , A61M2205/197 , Y10S604/905
摘要: A pre-slit injection site (34) includes a housing (40) with a flow path therethrough. A first end (42) of the housing (40) carries a pre-slit septum (52). One form of a blunt cannula (98), usable with the injection site (34), carries a locking member (100). When the pre-slit injection site (34) slidably receives the blunt cannula (98), the locking member (100) latches to the injection site (34) and creates a mechanically coupled unit. Another form of the cannula (280) includes a tube having a tapered distal end region (298) and having elongate discharge slots (294) for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post (330), an annular barb (394), and axially oriented grooves (268).
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公开(公告)号:US5797897A
公开(公告)日:1998-08-25
申请号:US470380
申请日:1995-06-06
IPC分类号: A61M39/02 , A61J1/00 , A61J1/05 , A61J1/10 , A61J1/14 , A61J1/20 , A61M5/00 , A61M5/162 , A61M25/00 , A61M25/02 , A61M37/00 , A61M39/00 , A61M39/04 , A61M39/14 , A61M29/00
CPC分类号: A61M39/1011 , A61J1/2089 , A61J1/2096 , A61M39/045 , A61M39/14 , A61M5/162 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2037 , A61J1/2044 , A61J1/2055 , A61J2200/10 , A61M2039/1033 , A61M2039/1072 , A61M2039/1077 , A61M2205/195 , A61M2205/197
摘要: A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. One form of a blunt cannula, usable with the injection site, carries a locking member. When the pre-slit injection site slidably receives the blunt cannula, the locking member latches to the injection site and creates a mechanically coupled unit. Another form of the cannula includes a tube having a tapered distal end region and having elongate discharge slots for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post, an annular barb, and axially oriented grooves.
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公开(公告)号:US5776116A
公开(公告)日:1998-07-07
申请号:US473524
申请日:1995-06-07
申请人: George A. Lopez , Virgil R. Laul
发明人: George A. Lopez , Virgil R. Laul
CPC分类号: A61M39/1011 , A61M39/14 , A61M2039/1027 , A61M2039/1033 , A61M2039/1072 , A61M2205/195 , A61M2205/197 , Y10S604/905
摘要: Disclosed is a connector for introducing medication into a patient in a safe, convenient way. It comprises a pair of plastic tubular members adapted to be manually pushed together to engage in a male-female relationship, and a locking mechanism that detachably secures the members together. The male member has a sealed entry port at its end, and the female member safely houses within it a needle which centrally pierces the seal of the port upon engagement of the members. Preferably, the locking mechanism provides a "click" sound when it locks the members together.
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公开(公告)号:US5656032A
公开(公告)日:1997-08-12
申请号:US451520
申请日:1995-05-26
申请人: Marshall S. Kriesel , Farhad Kazemzadeh , Matthew Kriesel , William Feng , Steve C. Barber , William J. Kluck
发明人: Marshall S. Kriesel , Farhad Kazemzadeh , Matthew Kriesel , William Feng , Steve C. Barber , William J. Kluck
CPC分类号: A61M5/1409 , A61M5/1413 , A61M5/14248 , A61M5/152 , A61M2005/1581 , A61M2205/197 , A61M5/1407 , Y10S128/12
摘要: An apparatus for accurately infusing fluids into a patient at specific rates over an extended period of time and the method for making same. The apparatus includes one or more dispensers, of a low profile, laminate or layered construction each having a stored energy source in the form of a distendable membrane or an elastomeric cellular mass, which in cooperation with the base, defined a fluid chamber having a fluid inlet and a fluid outlet. The apparatus further includes, in lieu of a rigid ullage, a high novel, conformable ullage made of yieldable materials. The conformable ullage uniquely conforms to the shape of elastomeric membrane as the membrane returns to its less distended configuration. This arrangement will satisfy even the most stringent delivery tolerance requirements and will elegantly overcome the limitations of materials selection encountered in devices embodying the rigid ullage construction. Additionally, with the novel ullage construction, the ullage can be located either between the base and the fluid to be delivered, or alternatively, can be located between the elastomeric membrane and the fluid to be delivered. Further, a plurality of subreservoirs can be associated with a single ullage thereby making it possible to incorporate a wide variety of delivery profiles within a single device.
摘要翻译: 一种用于在更长时间内以特定速率准确地将流体注入患者体内的装置及其制造方法。 该设备包括一个或多个分散器,其具有低轮廓,层压或分层结构,每个分配器具有可膨胀膜或弹性体泡沫体形式的储存能量源,其与基底配合,限定了具有流体的流体室 入口和流体出口。 该装置还包括代替刚性缺损的由可屈服材料制成的高度新颖的,适合的缺口。 随着膜返回到较少膨胀的构型,适形的填充与弹性膜的形状完全一致。 这种布置将满足最严格的交货公差要求,并且将优雅地克服在体现刚性空间结构的装置中遇到的材料选择的限制。 另外,随着新颖的空白结构,空白可以位于基底和要输送的流体之间,或者可以位于弹性膜和要输送的流体之间。 此外,多个子储存器可以与单个空白相关联,从而使得可以在单个装置内并入多种递送曲线。
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公开(公告)号:US5545139A
公开(公告)日:1996-08-13
申请号:US349404
申请日:1994-12-02
申请人: Marshall S. Kriesel
发明人: Marshall S. Kriesel
CPC分类号: A61M5/1409 , A61M5/1413 , A61M5/152 , A61J1/201 , A61J1/2075 , A61J1/2082 , A61J1/2096 , A61M2205/197 , A61M2209/045 , A61M5/1407 , A61M5/14248 , Y10S128/12
摘要: A fluid container assembly which can be aseptically filled in the field with selected fluids and one which is specially designed for sterile coupling and use with fluid dispensing and delivery devices of the character that embody stored energy sources such as compressible cellular masses and distendable elastomeric membranes that form, in conjunction with a cooperating base, fluid chambers for containing the fluid to be dispensed.
摘要翻译: 一种流体容器组件,其可以在选定的流体中无菌地填充在现场,并且专门设计用于无菌耦合和与具有体现储存能量源的流体分配和输送装置一起使用的流体容器组件,例如可压缩的细胞块和可膨胀的弹性体膜, 与配合的基座一起形成用于容纳要分配的流体的流体室。
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