公开(公告)号：US08748665B2

公开(公告)日：2014-06-10

申请号：US13318257

申请日：2010-05-06

申请人： Tilmann Steinmetz ,  Michael Nilles ,  Lucia Koenigsmann ,  Andreas Heussler ,  Nikolaus Zafred

发明人： Tilmann Steinmetz ,  Michael Nilles ,  Lucia Koenigsmann ,  Andreas Heussler ,  Nikolaus Zafred

IPC分类号： C07C209/00

CPC分类号： B01D11/043 ,  B01D3/141 ,  B01D3/40 ,  C07C209/86 ,  C07C211/46

摘要： The invention relates to a process for obtaining at least one aromatic amine from a liquid mixture comprising water and the at least one aromatic amine by extracting with at least one nitroaromatic in an extraction column (1) to form an essentially water- comprising raffinate stream and an extract stream comprising the at least one nitroaromatic and the aromatic amine. The extraction column (1) is divided by a dividing wall (3) into two regions (5, 7), and, in the case of an amount of liquid for separation which is less than a minimum cross sectional loading of the entire extraction column (1), the liquid mixture to be separated is fed only to one of the regions (5, 7) of the extraction column (1) divided by the dividing wall (3). The invention further relates to a process for preparing an aromatic amine and to an apparatus for separating a liquid mixture comprising water and at least one aromatic amine by extracting with at least one nitroaromatic, comprising an extraction column (1).

摘要翻译： 本发明涉及一种从包含水和至少一种芳族胺的液体混合物中获得至少一种芳族胺的方法，其通过在提取塔（1）中用至少一种硝基芳族化合物萃取以形成基本上含水的萃余液流和 包含至少一种硝基芳族和芳族胺的提取物流。 萃取塔（1）由分隔壁（3）分成两个区域（5,7），并且在分离液体的量小于整个萃取塔的最小横截面负荷的情况下 （1）中，待分离的液体混合物仅被供给到由分隔壁（3）分隔的萃取塔（1）的区域（5,7）中的一个。 本发明还涉及一种制备芳族胺的方法，以及用于通过用至少一种包含萃取塔（1）的硝基芳族化合物萃取来分离包含水和至少一种芳族胺的液体混合物的装置。

公开(公告)号：US08492584B2

公开(公告)日：2013-07-23

申请号：US12674466

申请日：2008-08-18

申请人： Joaquim Henrique Teles ,  Steffen Oehlenschläger ,  Kai Gumlich ,  Martin Schäfer ,  Stephan Lamm ,  Stefan Berg ,  Michael Nilles ,  Hans-Peter Schildberg ,  Tilo John ,  Peter Zehner

发明人： Joaquim Henrique Teles ,  Steffen Oehlenschläger ,  Kai Gumlich ,  Martin Schäfer ,  Stephan Lamm ,  Stefan Berg ,  Michael Nilles ,  Hans-Peter Schildberg ,  Tilo John ,  Peter Zehner

IPC分类号： C07C51/215

CPC分类号： C07C51/235 ,  Y02P20/582 ,  C07C53/126 ,  C07C53/122

摘要： The invention relates to a process for oxidizing at least one organic substance with oxygen, which comprises the following steps: (a) adding the at least one organic substance as a liquid and an oxygenous gas stream to a first reaction stage to form a reaction mixture, at least some of the oxygen reacting with the organic compound to form a reaction product, (b) adding the reaction mixture from the first reaction stage to an adiabatically operated reaction stage in which the unconverted organic substance reacts further at least partly to give the product. The invention further relates to an apparatus for performing the process.

摘要翻译： 本发明涉及用氧氧化至少一种有机物质的方法，其包括以下步骤：（a）将至少一种有机物质作为液体和含氧气流加入到第一反应阶段以形成反应混合物 ，至少一些氧与有机化合物反应以形成反应产物，（b）将反应混合物从第一反应阶段加入至绝热操作的反应阶段，其中未转化的有机物质至少部分地进一步反应，得到 产品。 本发明还涉及一种用于执行该过程的装置。

公开(公告)号：US20120083626A1

公开(公告)日：2012-04-05

申请号：US13318257

申请日：2010-05-06

申请人： Tilmann Steinmetz ,  Michael Nilles ,  Lucia Koenigsmann ,  Andreas Heussler ,  Nikolaus Zafred

发明人： Tilmann Steinmetz ,  Michael Nilles ,  Lucia Koenigsmann ,  Andreas Heussler ,  Nikolaus Zafred

IPC分类号： C07C209/84 ,  B01D11/04

CPC分类号： B01D11/043 ,  B01D3/141 ,  B01D3/40 ,  C07C209/86 ,  C07C211/46

摘要： The invention relates to a process for obtaining at least one aromatic amine from a liquid mixture comprising water and the at least one aromatic amine by extracting with at least one nitroaromatic in an extraction column (1) to form an essentially water-comprising raffinate stream and an extract stream comprising the at least one nitroaromatic and the aromatic amine. The extraction column (1) is divided by a dividing wall (3) into two regions (5, 7), and, in the case of an amount of liquid for separation which is less than a minimum cross sectional loading of the entire extraction column (1), the liquid mixture to be separated is fed only to one of the regions (5, 7) of the extraction column (1) divided by the dividing wall (3). The invention further relates to a process for preparing an aromatic amine and to an apparatus for separating a liquid mixture comprising water and at least one aromatic amine by extracting with at least one nitroaromatic, comprising an extraction column (1).

摘要翻译： 本发明涉及一种从包含水和至少一种芳族胺的液体混合物中通过在提取塔（1）中用至少一种硝基芳族化合物萃取以形成基本上含水的萃余液流而获得至少一种芳族胺的方法， 包含至少一种硝基芳族和芳族胺的提取物流。 萃取塔（1）由分隔壁（3）分成两个区域（5,7），并且在分离液体的量小于整个萃取塔的最小横截面负荷的情况下 （1）中，待分离的液体混合物仅被供给到由分隔壁（3）分隔的萃取塔（1）的区域（5,7）中的一个。 本发明还涉及一种制备芳族胺的方法，以及用于通过用至少一种包含萃取塔（1）的硝基芳族化合物萃取来分离包含水和至少一种芳族胺的液体混合物的装置。

公开(公告)号：US07015361B2

公开(公告)日：2006-03-21

申请号：US10073248

申请日：2002-02-13

申请人： Peter Zehner ,  Michael Nilles

发明人： Peter Zehner ,  Michael Nilles

IPC分类号： C07C45/50 ,  B01J10/00

CPC分类号： C07C45/50 ,  B01J19/006 ,  B01J19/2435 ,  B01J19/246 ,  B01J2219/00033 ,  B01J2219/00083 ,  B01J2219/00108 ,  B01J2219/0011 ,  B01J2219/00182 ,  B01J2219/00777 ,  C07C47/12

摘要： Olefins having at least 6 carbon atoms are hydroformylated in the presence of a homogeneous catalyst in a continuous process in which a) a vertical tall cylindrical reactor (1) whose interior space is divided by means of internals (2) into at least two reaction chambers which extend essentially in the longitudinal direction of the reactor is used, b) at least one olefin is introduced into the reactor together with synthesis gas at the lower end of the first reaction chamber, c) a partially reacted reaction mixture is conveyed from the upper end of a reaction chamber to the lower end of a next reaction chamber; and d) the hydroformylated olefin is taken off at the upper end of the last reaction chamber. The process allows a high conversion at a given reactor volume.

摘要翻译： 具有至少6个碳原子的烯烃在连续过程中在均相催化剂存在下加氢甲酰化，其中a）垂直的高圆柱形反应器（1），其内部空间通过内件（2）分成至少两个反应室 使用基本上在反应器的纵向延伸的方法，b）至少一种烯烃与第一反应室下端的合成气一起引入反应器，c）部分反应的反应混合物从上部 反应室的末端到下一个反应室的下端; 和d）加氢甲酰化烯烃在最后反应室的上端取出。 该方法允许在给定反应器体积下的高转化率。

公开(公告)号：US20060004231A1

公开(公告)日：2006-01-05

申请号：US11218532

申请日：2005-09-06

申请人： Peter Zehner ,  Michael Nilles

发明人： Peter Zehner ,  Michael Nilles

IPC分类号： C07C45/49

CPC分类号： C07C45/50 ,  B01J19/006 ,  B01J19/2435 ,  B01J19/246 ,  B01J2219/00033 ,  B01J2219/00083 ,  B01J2219/00108 ,  B01J2219/0011 ,  B01J2219/00182 ,  B01J2219/00777 ,  C07C47/12

摘要： Olefins having at least 6 carbon atoms are hydroformylated in the presence of a homogeneous catalyst in a continuous process in which a) a vertical tall cylindrical reactor (1) whose interior space is divided by means of internals (2) into at least two reaction chambers which extend essentially in the longitudinal direction of the reactor is used, b) at least one olefin is introduced into the reactor together with synthesis gas at the lower end of the first reaction chamber, c) a partially reacted reaction mixture is conveyed from the upper end of a reaction chamber to the lower end of a next reaction chamber; and d) the hydroformylated olefin is taken off at the upper end of the last reaction chamber. The process allows a high conversion at a given reactor volume.

公开(公告)号：US20110137077A1

公开(公告)日：2011-06-09

申请号：US12674466

申请日：2008-08-18

申请人： Joaquim H. Teles ,  Steffen Oehlenschläger ,  Kai Gumlich ,  Martin Schäfer ,  Stephan Lamm ,  Stefan Berg ,  Michael Nilles ,  Hans-Peter Schildberg ,  Tilo John ,  Peter Zehner

发明人： Joaquim H. Teles ,  Steffen Oehlenschläger ,  Kai Gumlich ,  Martin Schäfer ,  Stephan Lamm ,  Stefan Berg ,  Michael Nilles ,  Hans-Peter Schildberg ,  Tilo John ,  Peter Zehner

IPC分类号： C07C51/235 ,  B01J8/04

CPC分类号： C07C51/235 ,  Y02P20/582 ,  C07C53/126 ,  C07C53/122

摘要： The invention relates to a process for oxidizing at least one organic substance with oxygen, which comprises the following steps: (a) adding the at least one organic substance as a liquid and an oxygenous gas stream to a first reaction stage to form a reaction mixture, at least some of the oxygen reacting with the organic compound to form a reaction product, (b) adding the reaction mixture from the first reaction stage to an adiabatically operated reaction stage in which the unconverted organic substance reacts further at least partly to give the product. The invention further relates to an apparatus for performing the process.

摘要翻译： 本发明涉及用氧氧化至少一种有机物质的方法，其包括以下步骤：（a）将至少一种有机物质作为液体和含氧气流加入到第一反应阶段以形成反应混合物 ，至少一些氧与有机化合物反应以形成反应产物，（b）将反应混合物从第一反应阶段加入至绝热操作的反应阶段，其中未转化的有机物质至少部分地进一步反应，得到 产品。 本发明还涉及一种用于执行该过程的装置。

公开(公告)号：US07351384B2

公开(公告)日：2008-04-01

申请号：US11218532

申请日：2005-09-06

申请人： Peter Zehner ,  Michael Nilles

发明人： Peter Zehner ,  Michael Nilles

IPC分类号： B01J10/00 ,  B01J19/00

CPC分类号： C07C45/50 ,  B01J19/006 ,  B01J19/2435 ,  B01J19/246 ,  B01J2219/00033 ,  B01J2219/00083 ,  B01J2219/00108 ,  B01J2219/0011 ,  B01J2219/00182 ,  B01J2219/00777 ,  C07C47/12

摘要： Olefins having at least 6 carbon atoms are bydroformylated in the presence of a homogenous catalyst in a continuous process in which a) a vertical tall cylindrical reactor (1) whose interior space is divided by means of internals (2). into at least two reaction chambers which extend essentially in the longitudinal direction of the reactor is used, b) at least one olefin is introduced into the reactor together with synthesis gas at the lower end of the first reaction chamber, c) a partially reacted reaction mixture is conveyed from the upper end of a reaction chamber to the lower end of a next reaction chamber; and d) the hydroformylated olefin is taken off at the upper end of the last reaction chamber. The process allows a high conversion at a given reactor volume.

摘要翻译： 具有至少6个碳原子的烯烃在连续过程中在均匀催化剂存在下加氢甲酰化，其中a）垂直的高柱形反应器（1），其内部空间通过内件（2）分成至少两个反应室 使用基本上在反应器的纵向延伸的方法，b）至少一种烯烃与第一反应室下端的合成气一起引入反应器，c）部分反应的反应混合物从上部 反应室的末端到下一个反应室的下端; 和d）加氢甲酰化烯烃在最后反应室的上端取出。 该方法允许在给定反应器体积下的高转化率。

公开(公告)号：US06838061B1

公开(公告)日：2005-01-04

申请号：US09831402

申请日：1999-11-23

申请人： Stefan Berg ,  Peter Zehner ,  Regina Benfer ,  Jörn Müller ,  Michael Nilles ,  Ralf Schulz ,  Dieter Stützer

发明人： Stefan Berg ,  Peter Zehner ,  Regina Benfer ,  Jörn Müller ,  Michael Nilles ,  Ralf Schulz ,  Dieter Stützer

IPC分类号： B01J8/22 ,  B01J10/00 ,  B01J19/00 ,  B01J19/24 ,  B01J19/26 ,  C07B61/00 ,  C07C45/72 ,  C07C51/235 ,  C07C53/122 ,  F28D7/00

CPC分类号： C07C45/72 ,  B01J8/226 ,  B01J8/228 ,  B01J10/002 ,  B01J19/006 ,  B01J19/246 ,  B01J19/2465 ,  B01J2208/00123 ,  B01J2219/00078 ,  B01J2219/00777

摘要： A reactor (1) of high cylindrical construction for continuously carrying out gas-liquid, liquid-liquid or gas-liquid-solid reactions, provided with a downward-directed jet nozzle (2) via which the starting materials and the reaction mixture are fed in and which is located in the upper region of the reactor, and provided with an offtake (3), preferably in the lower region of the reactor, via which the reaction mixture is conveyed via an external circuit back to the jet nozzle (2) by means of a pump (P), wherein a guide tube (4) which extends essentially over the total length of the reactor (1) with the exception of the reactor ends and has a cross-sectional area in the range from one tenth to one half of the cross-sectional area of the reactor (1) is located concentrically in the reactor (1), and the jet nozzle (2) is located above the upper end of the guide tube (4), preferably at a distance of from one eighth of the guide tube diameter to one guide tube diameter, or projects into the guide tube (4) to a depth up to a plurality of guide tube diameters is proposed. A heat exchanger, in particular a heat exchanger having heat exchange tubes (6), preferably running parallel to the guide tube, welded in between plates (5), is integrated into the annular space.

摘要翻译： 一种高筒形结构的反应器（1），用于连续地进行气液，液 - 液或气 - 液 - 固反应，设有向下的喷射喷嘴（2），原料和反应混合物通过该喷嘴 并且其位于反应器的上部区域中，并且优选地在反应器的下部区域中设置有出料口（3），经由该反应混合物经由外部回路将反应混合物输送回到喷嘴（2） 通过泵（P），其中除了反应器端部之外基本上延伸到反应器（1）的总长度上的导管（4），并且横截面积在十分之一到 反应器（1）的横截面积的一半是同心地位于反应器（1）中，并且喷嘴（2）位于导管（4）的上端之上，优选距离 从引导管直径的八分之一到一个导管直径，或投入到 引导管（4）的深度达到多个导管直径。 热交换器，特别是具有焊接在板（5）之间的平行于引导管的热交换管（6）的换热器（6）整合到环形空间中。

公开(公告)号：US5919987A

公开(公告)日：1999-07-06

申请号：US716216

申请日：1996-09-13

申请人： Heinz-Josef Kneuper ,  Maik Aron ,  Frank-Michael Korgitzsch ,  Michael Nilles ,  Wolfgang Harder ,  Michael Roper ,  Rocco Paciello

发明人： Heinz-Josef Kneuper ,  Maik Aron ,  Frank-Michael Korgitzsch ,  Michael Nilles ,  Wolfgang Harder ,  Michael Roper ,  Rocco Paciello

IPC分类号： B01J23/46 ,  B01J31/40 ,  C07B61/00 ,  C07C27/22 ,  C07C29/141 ,  C07C29/16 ,  C07C31/02 ,  C07C45/50 ,  C07C45/80 ,  C07C47/02 ,  C07C51/235 ,  C07C209/00 ,  C07C45/00

CPC分类号： B01J31/20 ,  B01J31/4046 ,  C07C209/00 ,  C07C29/141 ,  C07C29/16 ,  C07C45/50 ,  C07C45/80 ,  C07C51/235 ,  B01J2231/321 ,  B01J23/464 ,  B01J2531/822 ,  B01J31/181 ,  B01J31/1815 ,  B01J31/1825 ,  B01J31/183 ,  Y02P20/584

摘要： An industrial preparation of aldehydes and/or alcohols from olefins of more than 3 carbon atoms by a catalytic hydroformylation of the olefin reactant at a pressure of from 50 to 1000 bar and a temperature of from 50 to 180.degree. C. in the presence of an uncomplexed rhodium catalyst homogeneously dissolved in the reaction medium. The catalytic activity of the rhodium is maintained, first by extracting it from the initially discharged reaction mixture by means of an aqueous solution of a nitrogen-containing complexing agent such as sulfonated or carboxylated pyridines, quinolines or the like. In a recycle of the complexed rhodium to be reused in the hydroformylation reaction, the aqueous rhodium-containing extract is fed to a precarbonylation stage where it subjected to a required precarbonylation in the presence of an essentially water-insoluble organic liquid and in the presence of carbon monoxide, synthesis gas or another gas mixture containing carbon monoxide at from 50 to 1000 bar and from 50 to 180.degree. C. The mixture discharged from this precarbonylation stage is then separated into an organic phase containing the main part of the rhodium and an aqueous phase containing the complexing agent. The resulting rhodium-containing organic phase with the regenerated catalyst is then fed into the hydroformylation stage to complete its recycle.

摘要翻译： PCT No.PCT / EP95 / 00825 Sec。 371日期1996年9月13日 102（e）日期1996年9月13日PCT 1995年3月6日PCT公布。 WO95 / 25080 PCT公开 日期1995年9月21日通过在50至1000巴的压力和50至180℃的温度下通过烯烃反应物的催化加氢甲酰化来工业制备大于3个碳原子的烯烃的醛和/或醇。 在均匀溶解在反应介质中的未络合的铑催化剂存在下进行。 保持铑的催化活性，首先通过含氮络合剂如磺化或羧化吡啶，喹啉等的水溶液从最初排出的反应混合物中提取铑的催化活性。 在加氢甲酰化反应中重复使用的复合铑的再循环中，含水铑萃取物进料到预羰化阶段，其中在基本上不溶于水的有机液体存在下进行所需的预羰基化， 一氧化碳，合成气或含有一氧化碳的另一种气体混合物，从50至1000巴和50至180℃。然后将从该预羰化阶段排出的混合物分离成含有主要部分铑的有机相， 相含有络合剂。 然后将所得到的含再生催化剂的含铑有机相进料到加氢甲酰化阶段以完成其再循环。