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公开(公告)号:US20240287129A1
公开(公告)日:2024-08-29
申请号:US18640494
申请日:2024-04-19
发明人: David MacMillan , Daniel Novoa , Stefan McCarver
CPC分类号: C07K1/113 , B01J31/181 , B01J31/1815 , B01J35/39 , C07K1/107 , C07K5/0205 , C25B3/29 , B01J2231/324 , B01J2231/348 , B01J2531/827 , B01J2540/12 , B01J2540/22 , B01J2540/225
摘要: Synthetic methods are described herein operable to efficiently produce a wide variety of molecular species through conjugate additions via decarboxylative mechanisms. For example, methods of functionalization of peptide residues are described, including selective functionalization of peptide C-terminal residues. In one aspect, a method of peptide functionalization comprises providing a reaction mixture including a Michael acceptor and a peptide and coupling the Michael acceptor with the peptide via a mechanism including decarboxylation of a peptide reside.
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公开(公告)号:US20240181438A1
公开(公告)日:2024-06-06
申请号:US18278947
申请日:2022-03-01
发明人: Michal Szostak , Qun Zhao , Md. Mahbubur Rahman
CPC分类号: B01J31/2273 , B01J31/181 , B01J31/2291 , B01J37/04 , C07D233/58 , C07F1/005 , C07F1/08 , C07F5/027 , C07F15/006 , B01J2231/323 , B01J2531/16 , B01J2531/17 , B01J2531/18 , B01J2531/824
摘要: The present disclosure relates in part to novel complexes of unsymmetrical N-heterocylic carbene (NHC) ligands and group 10 or 11 metals. The present disclosure further relates to methods of electrophilic functionalization of alkynes and/or nitriles using the NHC catalysts described herein.
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公开(公告)号:US11981704B2
公开(公告)日:2024-05-14
申请号:US17469102
申请日:2021-09-08
发明人: David MacMillan , Daniel Novoa , Stefan McCarver
CPC分类号: C07K1/113 , B01J31/181 , B01J31/1815 , B01J35/004 , C07K1/107 , C07K5/0205 , C25B3/29 , B01J2231/324 , B01J2231/348 , B01J2531/827 , B01J2540/12 , B01J2540/22 , B01J2540/225
摘要: Synthetic methods are described herein operable to efficiently produce a wide variety of molecular species through conjugate additions via decarboxylative mechanisms. For example, methods of functionalization of peptide residues are described, including selective functionalization of peptide C-terminal residues. In one aspect, a method of peptide functionalization comprises providing a reaction mixture including a Michael acceptor and a peptide and coupling the Michael acceptor with the peptide via a mechanism including decarboxylation of a peptide reside.
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4.
公开(公告)号:US11773074B2
公开(公告)日:2023-10-03
申请号:US17087926
申请日:2020-11-03
发明人: Shannon Stahl , Stephen Tereniak
IPC分类号: C07D333/22 , B01J31/04 , C07D277/32 , B01J31/18 , C07D333/54 , B01J31/24 , B01J31/22
CPC分类号: C07D333/22 , B01J31/04 , B01J31/181 , B01J31/183 , B01J31/184 , B01J31/1815 , B01J31/1825 , B01J31/2239 , B01J31/2409 , C07D277/32 , C07D333/54 , B01J2231/46 , B01J2531/0205 , B01J2531/16 , B01J2531/824 , B01J2531/842 , B01J2540/10 , B01J2540/22 , B01J2540/225 , B01J2540/40
摘要: An oxidative homocoupling method of synthesizing certain 2,2′-bithiophenes from thiophenes using oxygen as the terminal oxidant is disclosed. In non-limiting examples, the method uses oxygen along with a catalytic system that includes palladium, an assistive ligand, and a non-palladium metal additive to catalyze one of the following reactions:
Associated catalytic systems and compositions are also disclosed.-
公开(公告)号:US11773040B2
公开(公告)日:2023-10-03
申请号:US17060455
申请日:2020-10-01
发明人: Elizabeth Papish , Aaron Vannucci
CPC分类号: C07C41/18 , B01J31/181 , B01J31/1815 , B01J31/2295 , C07C1/20 , B01J2531/821 , C07C2601/16
摘要: Disclosed are methods of selective hydrodeoxygenation of aromatic compounds by using catalyst systems comprising N-heterocyclic carbene (NHC) and 4-pyridinol-derived pincer ligands and metal complexes containing these ligands.
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6.
公开(公告)号:US20190161689A1
公开(公告)日:2019-05-30
申请号:US16150718
申请日:2018-10-03
申请人: Liudmila Aleksandrovna Tyurina , Alexander Ivanovich Tyurin , Irina Gennadievna Tarkhanova , Alexey Aleksandrovich Tyurin
发明人: Liudmila Aleksandrovna Tyurina , Alexander Ivanovich Tyurin , Irina Gennadievna Tarkhanova , Alexey Aleksandrovich Tyurin
CPC分类号: C10G27/08 , B01D53/263 , B01D53/8603 , B01D53/8612 , B01D2251/90 , B01D2252/2023 , B01D2255/20761 , B01D2256/24 , B01D2256/245 , B01D2257/304 , B01D2257/306 , B01J27/122 , B01J27/128 , B01J27/13 , B01J27/32 , B01J31/02 , B01J31/0238 , B01J31/0244 , B01J31/0247 , B01J31/16 , B01J31/1805 , B01J31/181 , B01J2531/16 , B01J2531/842 , C07C7/11 , C07C7/1485 , C10G27/10 , C10G2300/202 , C10G2300/4081
摘要: This application is in the field of technologies for desulfurization and demercaptanization of raw gaseous hydrocarbons (including natural gas, tail gas, technological gas, etc, including gaseous media). It can be used for simultaneous dehydration and desulfurization/demercaptanization of any kind of raw gaseous hydrocarbons.
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公开(公告)号:US20180179248A1
公开(公告)日:2018-06-28
申请号:US15579741
申请日:2016-06-03
发明人: David MACMILLAN , Daniel NOVOA , Stefan MCCARVER
CPC分类号: C07K1/113 , B01J31/181 , B01J31/1815 , B01J35/004 , B01J2231/324 , B01J2231/348 , B01J2531/827 , B01J2540/12 , B01J2540/22 , B01J2540/225 , C07K1/107 , C07K5/0205 , C25B3/10
摘要: Synthetic methods are described herein operable to efficiently produce a wide variety of molecular species through conjugate additions via decarboxylative mechanisms. For example, methods of functionalization of peptide residues are described, including selective functionalization of peptide C-terminal residues. In one aspect, a method of peptide functionalization comprises providing a reaction mixture including a Michael acceptor and a peptide and coupling the Michael acceptor with the peptide via a mechanism including decarboxylation of a peptide reside.
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公开(公告)号:US09918389B2
公开(公告)日:2018-03-13
申请号:US14477855
申请日:2014-09-04
发明人: Feng Liu , Maria Rzeznik
CPC分类号: H05K3/181 , B01J31/181 , B01J31/2295 , B01J2231/005 , B01J2531/824 , C23C18/1641 , C23C18/1658 , C23C18/166 , C23C18/2086 , C23C18/24 , C23C18/285 , C23C18/30 , C23C18/32 , C23C18/34 , C23C18/38 , C23C18/40 , C23C18/50 , H05K3/422 , H05K2203/0709
摘要: Pyrazine derivatives which contain one or more electron donating groups on the ring are used as catalytic metal complexing agents in aqueous alkaline environments to catalyze electroless metal plating on metal clad and un-clad substrates. The catalysts are monomers and free of tin and antioxidants.
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公开(公告)号:US20180009759A1
公开(公告)日:2018-01-11
申请号:US15543714
申请日:2016-01-15
IPC分类号: C07D215/38 , C07D215/18 , C07D215/12 , C07D215/04 , B01J31/18 , C07D215/20 , B01J31/04
CPC分类号: C07D215/38 , B01J31/04 , B01J31/181 , C07D215/04 , C07D215/12 , C07D215/18 , C07D215/20
摘要: The present invention discloses novel N-Heterocyclic compounds of formula A, [Formula A] And a ligand-enabled palladium-catalyzed process for preparation of novel N-Heterocyclic compounds of Formula A via C—H alkynylation of N-heterocycles with alkynyl halides.
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公开(公告)号:US09713808B2
公开(公告)日:2017-07-25
申请号:US14797834
申请日:2015-07-13
IPC分类号: C07F11/00 , B01J31/18 , B01J31/22 , C07C6/04 , C07C41/30 , C07C67/475 , C07C209/68 , C07C303/40 , C07F7/08 , C07C209/64 , C07F5/02
CPC分类号: B01J31/2295 , B01J31/1805 , B01J31/181 , B01J31/1825 , B01J31/2226 , B01J31/2265 , B01J31/2278 , B01J2231/54 , B01J2231/543 , B01J2531/0266 , B01J2531/0288 , B01J2531/64 , B01J2531/66 , B01J2540/225 , B01J2540/40 , C07B2200/09 , C07C6/04 , C07C41/30 , C07C67/475 , C07C209/64 , C07C209/68 , C07C303/40 , C07C2531/18 , C07C2531/22 , C07C2601/14 , C07C2601/16 , C07C2602/10 , C07F5/025 , C07F7/083 , C07F11/00 , C07F11/005 , C07C13/28 , C07C11/02 , C07C15/50 , C07C43/166 , C07C69/593 , C07C311/18 , C07C211/53
摘要: The present invention relates generally to catalysts and processes for the Z-selective formation of internal olefin(s) from terminal olefin(s) via homo-metathesis reactions.
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