公开(公告)号：US20120089030A1

公开(公告)日：2012-04-12

申请号：US13144574

申请日：2010-01-18

申请人： Kevin Guze ,  Michael Short ,  Haishan Zeng ,  Stephen Sonis

发明人： Kevin Guze ,  Michael Short ,  Haishan Zeng ,  Stephen Sonis

IPC分类号： A61B6/00

CPC分类号： G01N21/65 ,  A61B5/0088 ,  A61B5/682 ,  G01N2021/656

摘要： A method and system for characterizing tissue includes a probe connected to a red LASER source and a Raman spectroscope. The probe includes at least excitation fiber and one or more emission fibers that connect the probe with the LASER source and the Raman spectroscope. The excitation fiber is connected to the red LASER source and terminates in the first end of the probe adjacent the tip of the probe. The emission fibers are connected to the Raman spectroscope and terminate in the first end of the probe adjacent the tip of the probe. In one embodiment, the excitation fiber extends through the central portion of the probe and one or more emission fibers are arranged around the excitation fiber. The tip of the probe is intended to come in contact with the tissue to be examined. The tip includes a central opening to allow red LASER radiation to project out of the end of the red excitation fiber on to the tissue and to permit Raman spectra to enter the emission fiber(s) and travel to the Raman spectroscope. The tip is constructed to have a predefined focal length to position the first end of the probe a predefined distance from the surface of the tissue being examined. The tip can be removable and tips having different focal lengths can be used to accommodate different types of tissues and examinations. A detector can convert the Raman spectra into signals and data for analysis by a computer system. The Raman spectra for tissue in a predefined location can be profiled such that the system can distinguish between healthy and diseased tissue.

摘要翻译： 用于表征组织的方法和系统包括连接到红色激光源和拉曼光谱仪的探针。 该探针至少包括激发光纤和将探头与激光源和拉曼光谱仪连接的一个或多个发射光纤。 激发光纤连接到红色激光源，并且终止于探头的第一端附近的探针尖端。 发射光纤连接到拉曼光谱仪并终止在探头的第一端附近探针的尖端。 在一个实施例中，激发光纤延伸穿过探针的中心部分，并且一个或多个发射光纤布置在激发光纤周围。 探针的尖端旨在与要检查的组织接触。 尖端包括中心开口，以允许红色激光辐射从红色激发光纤的末端突出到组织上，并允许拉曼光谱进入发射光纤并行进到拉曼光谱仪。 尖端被构造成具有预定的焦距，以将探针的第一端定位在距待检查组织的表面的预定距离处。 尖端可以是可移除的，并且可以使用具有不同焦距的尖端来适应不同类型的组织和检查。 检测器可以将拉曼光谱转换为信号和数据，以便计算机系统进行分析。 可以对预定位置中的组织的拉曼光谱进行分析，使得系统可以区分健康组织和患病组织。

公开(公告)号：US20130231573A1

公开(公告)日：2013-09-05

申请号：US13521218

申请日：2011-01-21

申请人： Haishan Zeng ,  Michael Short ,  Stephen Lam ,  Annette McWilliams

发明人： Haishan Zeng ,  Michael Short ,  Stephen Lam ,  Annette McWilliams

IPC分类号： A61B5/00

CPC分类号： A61B5/0075 ,  A61B5/0071 ,  A61B5/0084 ,  G01N21/65

摘要： Near-infrared Raman spectroscopy can be applied to identify preneoplastic lesions of the bronchial tree. Real-time in vivo Raman spectra of lung tissues may be obtained with a fiber optic catheter passed down the instrument channel of a bronchoscope. Using prototype apparatus, preneoplastic lesions were detected with sensitivity and specificity of 96 and 91% respectively. The use of Raman spectroscopy apparatus and methods in conjunction with other bronchoscopy imaging modalities can substantially reduce the number of false positive results.

摘要翻译： 近红外拉曼光谱可用于鉴定支气管树瘤的肿瘤前病变。 肺组织的实时体内拉曼光谱可以通过沿支气管镜仪器通道向下传播的光纤导管获得。 使用原型装置，分别检测到96和91％的敏感性和特异性的癌前病变。 使用拉曼光谱设备和方法与其他支气管镜检查成像模式联合可以大大减少假阳性结果的数量。

公开(公告)号：US20070199952A1

公开(公告)日：2007-08-30

申请号：US11725402

申请日：2007-03-19

申请人： M. Carpenter ,  Paul Furner ,  Thomas Gasper ,  Chris Kubicek ,  Leon Lemon ,  Brent Madsen ,  Kenneth Michaels ,  Cory Nelson ,  Michael Short ,  Gene Sipinski ,  Nathan Westphal

发明人： M. Carpenter ,  Paul Furner ,  Thomas Gasper ,  Chris Kubicek ,  Leon Lemon ,  Brent Madsen ,  Kenneth Michaels ,  Cory Nelson ,  Michael Short ,  Gene Sipinski ,  Nathan Westphal

IPC分类号： B67D5/08 ,  B67D3/00 ,  G04C23/42

CPC分类号： B65D83/262 ,  A61L9/14 ,  B05B11/3053 ,  B05B12/02 ,  B05B12/12 ,  B05B12/122 ,  B65D83/267

摘要： An automatic discharge device includes a housing having a top portion and a base portion, wherein surfaces defining a recess are provided therebetween for securely holding a container. At least one gear is disposed substantially between the recess and a rear panel of the housing. A drive motor is in association with the at least one gear. An actuator arm is also provided. Activation of the drive motor and the at least one gear provides for movement of the actuator arm between at least one of a pre-actuation position and a discharge position along a path that has a directional component parallel to a longitudinal axis of the recess.

摘要翻译： 自动排出装置包括具有顶部和基部的壳体，其中设置有凹部的表面设置在其间，用于牢固地保持容器。 至少一个齿轮基本上设置在壳体的凹部和后面板之间。 驱动马达与至少一个齿轮相关联。 还提供致动器臂。 驱动马达和至少一个齿轮的激活提供致动器臂在沿着具有平行于凹部的纵向轴线的方向分量的路径的预致动位置和排出位置中的至少一个之间的运动。

公开(公告)号：USD331751S

公开(公告)日：1992-12-15

申请号：US707399

申请日：1991-05-30

申请人： Michael Short

设计人： Michael Short

公开(公告)号：US07784157B1

公开(公告)日：2010-08-31

申请号：US11888948

申请日：2007-08-03

申请人： Michael Short ,  Michelle D. Short, legal representative

发明人： Michael Short

IPC分类号： A45F5/00

CPC分类号： A45F5/02 ,  A45F5/021 ,  H04B1/385 ,  H04B2001/3855 ,  H04M1/05 ,  Y10T24/1397

摘要： An apparatus which facilitates retaining a coil wire from a microphone onto a shirt. The device is used to retain the coil from a microphone to a location adjacent to a police officer's shirt. The microphone or other communication device has an alligator clip or other means by which it is clipped to a shirt. The microphone is attached to a coil which then is attached to a pack which is usually worn on the police officer's belt. The present invention provides a secure loop which is securely retained on the shirt and through which the microphone coil passes. As a result, when the microphone becomes dislodged, the loop provides a means by which the coil dangles from the loop and enables the microphone to remain adjacent to the police officer's shirt.

摘要翻译： 一种有助于将线圈线从麦克风保持在衬衫上的装置。 该设备用于将线圈从麦克风保留到与警察衬衫相邻的位置。 麦克风或其他通信设备具有鳄鱼夹或其它方式被夹到衬衫上。 麦克风连接到一个线圈上，然后线圈被连接到通常戴在警察带上的包装上。 本发明提供一种牢固地保持在衬衫上并且麦克风线圈通过的安全环。 结果，当麦克风变得脱落时，环路提供了一种方法，通过该装置线圈从环路中摆动并使麦克风能够保持与警察的衬衫相邻。

公开(公告)号：US20060076366A1

公开(公告)日：2006-04-13

申请号：US11247793

申请日：2005-10-11

申请人： Paul Furner ,  Thomas Gasper ,  Chris Kubicek ,  Leon Lemon ,  Brent Madsen ,  Nathan Westphal ,  Kenneth Michaels ,  Cory Nelson ,  M. Carpenter ,  Michael Short

发明人： Paul Furner ,  Thomas Gasper ,  Chris Kubicek ,  Leon Lemon ,  Brent Madsen ,  Nathan Westphal ,  Kenneth Michaels ,  Cory Nelson ,  M. Carpenter ,  Michael Short

IPC分类号： B65D83/14 ,  B65D83/00 ,  B65D83/06 ,  B65D83/20

CPC分类号： B65D83/262 ,  A01M1/2038 ,  A61L9/14 ,  A61L2209/11 ,  A61L2209/111 ,  A61L2209/134 ,  B05B11/3053 ,  B05B12/02 ,  B05B12/12 ,  B05B12/122

摘要： An automatic discharge device comprises a housing adapted to receive a container therein. An actuator arm is attached to the housing and movable between first and second positions. The actuator arm includes a dispensing bore therein. A drive unit is provided for automatically moving the actuator arm into one of the first and second positions in response to a signal from at least one of a timer, a sensor, and a manual switch. The actuator arm is adapted to engage and actuate a nozzle of the container in the first position and allow a fluid disposed in an interior of the container to be dispensed through the nozzle and the dispensing bore of the actuator arm.

摘要翻译： 自动排放装置包括适于在其中容纳容器的壳体。 致动器臂附接到壳体并且能够在第一和第二位置之间移动。 致动器臂在其中包括分配孔。 提供驱动单元，用于响应于来自定时器，传感器和手动开关中的至少一个的信号自动地将致动器臂移动到第一和第二位置之一。 致动器臂适于在第一位置接合和致动容器的喷嘴，并允许通过喷嘴和致动器臂的分配孔分配设置在容器内部的流体。

公开(公告)号：US6107274A

公开(公告)日：2000-08-22

申请号：US270121

申请日：1999-03-15

申请人： Adnan M. M. Mjalli ,  James Christopher Mason ,  Kristen Lee Arienti ,  Kevin Michael Short ,  Rachel Denise Anne Kimmich ,  Todd Kevin Jones

发明人： Adnan M. M. Mjalli ,  James Christopher Mason ,  Kristen Lee Arienti ,  Kevin Michael Short ,  Rachel Denise Anne Kimmich ,  Todd Kevin Jones

IPC分类号： C07D241/08 ,  A61K31/495 ,  A61K31/4985 ,  A61K38/00 ,  A61K38/12 ,  A61P3/10 ,  A61P43/00 ,  C07D471/04 ,  C07K5/078 ,  C07K5/12

CPC分类号： C07D241/08 ,  C07D471/04 ,  C07K5/06139 ,  A61K38/00

摘要： Compounds of formula A are disclosed: ##STR1## wherein R.sup.1 is aralkyl or cycloalkyl; R.sup.2 is cycloalkylmethyl, alkyl, or aralkyl;R.sup.3 is hydrogen, alkyl, substituted phenyl (including p-phenoxy-phenyl), or fluorene;R.sup.4 is hydrogen, alkyl, substituted phenyls (including 1-alkyl-4-carboxy-substituted phenyls), alkyl carboxylic acids;R.sup.5 is hydrogen or R.sup.1 and R.sup.5 taken together forming a tetrahydroisoquinoline ring or a piperidine ring.These compounds exhibit inhibitory action against fructose-1,6-bisphosphatase (FBPase) and are indicated in the treatment or management of Type II diabetes.

摘要翻译： 公开了式A的化合物：其中R 1是芳烷基或环烷基; R2是环烷基甲基，烷基或芳烷基; R3是氢，烷基，取代的苯基（包括对苯氧基 - 苯基）或芴; R4是氢，烷基，取代的苯基（包括1-烷基-4-羧基取代的苯基），烷基羧酸; R5是氢或R1和R5一起形成四氢异喹啉环或哌啶环。 这些化合物对果糖-1,6-二磷酸酶（FBPase）表现出抑制作用，并在II型糖尿病的治疗或治疗中表现出。

公开(公告)号：US20060248179A1

公开(公告)日：2006-11-02

申请号：US11118846

申请日：2005-04-29

申请人： Michael Short ,  Daniel Ford ,  Adrian Cowham

发明人： Michael Short ,  Daniel Ford ,  Adrian Cowham

IPC分类号： G06F15/173

CPC分类号： H04L41/06 ,  H04L41/0213 ,  H04L63/1416

摘要： A method and system for event-driven network management. A network management application is configured to detect a network event generated by an external application and to execute an action in response to detecting said network event, wherein the network management application is configurable to receive information describing the network event and the action. The network event is monitored for. In response to detecting the network event, the action is executed.

摘要翻译： 一种用于事件驱动的网络管理的方法和系统。 网络管理应用被配置为检测由外部应用产生的网络事件并且响应于检测到所述网络事件来执行动作，其中所述网络管理应用可配置为接收描述所述网络事件和所述动作的信息。 监控网络事件。 响应于检测到网络事件，执行动作。

公开(公告)号：US20050257326A1

公开(公告)日：2005-11-24

申请号：US10852927

申请日：2004-05-24

申请人： Rick Schneider ,  Steven Fricke ,  Michael Short ,  James Sawyer ,  Phillip Lindeman ,  Michael Carey

发明人： Rick Schneider ,  Steven Fricke ,  Michael Short ,  James Sawyer ,  Phillip Lindeman ,  Michael Carey

IPC分类号： A47L15/00 ,  D06F39/12 ,  B08B3/12

CPC分类号： A47L15/4268 ,  A47L15/4209 ,  D06F39/12

摘要： A side panel for a fabric care appliance is described. The side panel includes an embossed pattern for increasing a first natural frequency (or first harmonic) of the side panel. Preferably, the first natural frequency is substantially higher than any ordinary operating frequency or driving frequency of the appliance. For example, in a washing machine, the first natural frequency of the side panel is preferably at least 1.6 times greater than the maximum rotational frequency of a drum or tumbler of the machine.

摘要翻译： 描述了用于织物护理器具的侧面板。 侧板包括用于增加侧板的第一固有频率（或第一谐波）的压花图案。 优选地，第一固有频率基本上高于设备的任何普通工作频率或驱动频率。 例如，在洗衣机中，侧面板的第一固有频率优选为机器的滚筒或滚筒的最大转速的至少1.6倍。