公开(公告)号：US20100318147A1

公开(公告)日：2010-12-16

申请号：US12808190

申请日：2007-12-18

申请人： Mikael Forslund ,  Johan Eckerdal

发明人： Mikael Forslund ,  Johan Eckerdal

IPC分类号： A61N1/05 ,  A61N1/362 ,  A61N1/08 ,  A61N1/365 ,  A61N1/37

CPC分类号： A61N1/0573 ,  A61N1/0587

摘要： An implantable medical system for delivering pacing pulses to HIS bundle of a heart of a patient when implanted in said patient includes a medical lead, which is adapted to be attached with a distal end to tissue of said heart, including a at least two electrodes arranged being electrically separated from each other. The implantable medical device connectable to the medical lead includes a pacing circuit adapted to deliver the pacing pulses to said heart via the medical lead, a selection device connected between the pacing circuit and the electrodes adapted to selectively activate at least one of said electrodes, and a processing device adapted to control the selection device to selectively activate at least one of the electrodes to direct the pacing pulses to the HIS bundle.

摘要翻译： 一种可植入医疗系统，用于在植入患者心脏时向患者的心脏的HIS束输送起搏脉冲包括医用引线，其适于与远端结合到所述心脏的组织，所述远端包括至少两个电极， 彼此电隔离。 可连接到医疗引线的可植入医疗装置包括适于经由医用引线将起搏脉冲输送到心脏的起搏电路，连接在起搏电路和电极之间的选择装置，其适于选择性地激活所述电极中的至少一个，以及 处理装置，其适于控制所述选择装置选择性地激活所述电极中的至少一个以将所述起搏脉冲引导到所述HIS束。

公开(公告)号：US20100037457A1

公开(公告)日：2010-02-18

申请号：US12522001

申请日：2007-01-31

申请人： Anna Norlin Weissenrieder ,  Rolf Hill ,  Olof Stegfeldt ,  Marie Herstedt ,  Mikael Forslund ,  Susanne Nilssson

发明人： Anna Norlin Weissenrieder ,  Rolf Hill ,  Olof Stegfeldt ,  Marie Herstedt ,  Mikael Forslund ,  Susanne Nilssson

IPC分类号： H01R43/16

CPC分类号： H01B13/00 ,  A61N1/0573 ,  Y10T29/49073 ,  Y10T29/49124 ,  Y10T29/49169 ,  Y10T29/49174 ,  Y10T29/49201 ,  Y10T29/49218

摘要： In a method for manufacturing active fixation helices for the stimulation and/or sensing of organs, an elongated helix precursor body is produced that has one or more electrical conductors surrounded by an insulating material. This helix precursor body is then shaped into a helix, material removed in predetermined places in order to expose the areas of the conductors which will be used as electrodes in the final product. The body is coated with an electrically conducting biocompatible coating which is subsequently partly removed in continuous loops from around the electrodes in order to electrically insulate them from each other and to ensure that the electrically active areas of the electrodes are of the correct dimensions.

摘要翻译： 在用于制造用于刺激和/或感测器官的活动固定螺旋的方法中，制造了具有被绝缘材料包围的一个或多个电导体的细长螺旋前体体。 然后将该螺旋前体体成形为螺旋，在预定位置移除材料，以暴露将用作最终产品中的电极的导体区域。 该主体涂覆有导电生物相容性涂层，其随后部分地从电极周围以连续的环路去除，以使它们彼此电绝缘并且确保电极的电活性区域具有正确的尺寸。

公开(公告)号：US20060169144A1

公开(公告)日：2006-08-03

申请号：US10542617

申请日：2004-01-20

申请人： Mikael Forslund

发明人： Mikael Forslund

IPC分类号： B01D53/02

CPC分类号： B01J20/28028 ,  B01D39/163 ,  B01D46/0001 ,  B01J47/018

摘要： A pleatable filter structure for use in a filter panel, containing ion exchange particles distributed within a fibrous framework is expanded to contain enough space to allow the ion exchange particles to swell or to be in a swelled state as compared to dry ion exchange particles, without additional expansion of the filter structure. A method of manufacturing the filter structure involves subjecting the filter structure to a moisture treatment in which it is exposed to a humid or water containing environment, whereby the ion exchange particles swell and cause a permanent expansion of the filter structure.

公开(公告)号：US08968445B2

公开(公告)日：2015-03-03

申请号：US13254148

申请日：2010-03-02

申请人： Christian Lindahl ,  Guillaume Gallet ,  Mikael Forslund

发明人： Christian Lindahl ,  Guillaume Gallet ,  Mikael Forslund

IPC分类号： B01D53/02 ,  B01D46/52 ,  B01D39/16 ,  B01D46/00

CPC分类号： B01D46/521 ,  B01D39/1623 ,  B01D46/0036 ,  B01D46/0063 ,  B01D53/02 ,  B01D2239/0407 ,  B01D2239/065 ,  B01D2239/0654 ,  B01D2253/102 ,  B01D2253/202 ,  B01D2253/34 ,  B01D2259/4508 ,  B01D2279/51

摘要： The present invention provides regenerable pleated media and filter elements and combinations thereof for use in a clean room environment for removal of airborne molecular contamination. Disclosed is a pleated filter media for a clean room environment wherein the pleated filter media comprises at least an adsorbent first layer of activated carbon or polymer wherein said activated carbon or polymer together with fibers and/or an adhesion agent is enclosed between two second layers of non woven with a grid positioned on at least one side of either of the second layers or incorporated in the first layer for preventing deformation of the pleated filter media when regenerated by a heated air flow above 100° C. at 1 atm.

摘要翻译： 本发明提供可再生的打褶介质和过滤元件及其组合，用于洁净室环境中以除去空气中的分子污染。 公开了一种用于洁净室环境的打褶过滤介质，其中打褶的过滤介质至少包含活性炭或聚合物的吸附剂第一层，其中所述活性炭或聚合物与纤维和/或粘合剂一起被包封在两个第二层 非织造物，其格栅位于任一第二层的至少一侧，或者结合在第一层中，以防止在1atm下通过100℃以上的加热空气流再生时打褶的过滤介质的变形。

公开(公告)号：US20120022356A1

公开(公告)日：2012-01-26

申请号：US13262179

申请日：2009-10-30

申请人： Linn Olsen ,  Mikael Forslund ,  Henrik Djurling ,  Patrik Forsström ,  Leda Henriquez ,  Kenneth Dahlberg ,  Olof Stegfeldt ,  Åke Sivard

发明人： Linn Olsen ,  Mikael Forslund ,  Henrik Djurling ,  Patrik Forsström ,  Leda Henriquez ,  Kenneth Dahlberg ,  Olof Stegfeldt ,  Åke Sivard

IPC分类号： A61N1/05 ,  A61B5/04

CPC分类号： A61N1/057 ,  A61N1/3752

摘要： A medical implantable lead is adapted to be implanted into a human or animal body for monitoring and/or controlling of an organ inside the body. The lead has in a distal end, a combined fixation means and electrode member in form of a helix, which is connected to a rotatable tubular member being connected to a rotatable member at a proximal end of the lead, and which is rotatable in relation to the lead and extendable out from the distal end, by rotation of the control member and the tubular torque transferring member, to be able to fixate the distal end of the lead to the organ by being screwed into the tissue. The helix is electrically connected to a connector at the proximal end by means of at least one electrically conducting wire formed as an electrically conducting coil, which is separate from the tubular torque transferring member and unrotatable in relation to the lead and that has one or more individual wires, each including an electrically conducting wire core and a surrounding electrically insulating layer, wherein the rotatable control member is rotatable within the connector.

摘要翻译： 医用可植入引线适于植入人体或动物体内，用于监测和/或控制体内器官。 引线具有远端，组合的固定装置和螺旋形式的电极构件，其连接到可旋转的管状构件，该可旋转的管状构件在引线的近端处连接到可旋转构件，并且其可相对于 引线并且通过控制构件和管状扭矩传递构件的旋转从远端可伸出，以能够通过拧入组织而将引线的远端固定到器官。 螺旋线通过至少一个形成为导电线圈的导电线电连接到近端处的连接器，导电线圈与管状扭矩传递构件分离并且相对于引线不可旋转，并且具有一个或多个 各个电线各自包括导电线芯和周围的电绝缘层，其中可旋转控制构件可在连接器内旋转。

公开(公告)号：US20130156933A1

公开(公告)日：2013-06-20

申请号：US13549087

申请日：2012-07-13

申请人： Anna Norlin Weissenrieder ,  Rolf Hill ,  Olof Stegfeldt ,  Marie Herstedt ,  Mikael Forslund ,  Susanne Nilsson

发明人： Anna Norlin Weissenrieder ,  Rolf Hill ,  Olof Stegfeldt ,  Marie Herstedt ,  Mikael Forslund ,  Susanne Nilsson

IPC分类号： H01B13/00

CPC分类号： H01B13/00 ,  A61N1/0573 ,  Y10T29/49073 ,  Y10T29/49124 ,  Y10T29/49169 ,  Y10T29/49174 ,  Y10T29/49201 ,  Y10T29/49218

摘要： The present invention relates to methods for manufacturing active fixation helices for the stimulation and/or sensing of organs. A first embodiment of a method in accordance with the present invention for making a helix comprises a first step of producing an elongated helix precursor body comprising one or more electrical conductors surrounded by an insulating material. This helix precursor body is then shaped into a helix, material removed in predetermined places in order to expose the areas of the conductors which will be used as electrodes in the final product. The body is coated with an electrically conducting biocompatible coating which is subsequently partly removed in continuous loops from around the electrodes in order to electrically insulate them from each other and to ensure that the electrically active areas of the electrodes are of the correct dimensions.

摘要翻译： 本发明涉及用于制造用于刺激和/或感测器官的活动固定螺旋的方法。 根据本发明的用于制造螺旋的方法的第一实施例包括制造细长螺旋前体体的第一步骤，该主体包括由绝缘材料包围的一个或多个电导体。 然后将该螺旋前体体成形为螺旋，在预定位置移除材料，以暴露将用作最终产品中的电极的导体区域。 该主体涂覆有导电生物相容性涂层，其随后部分地从电极周围以连续的环路去除，以使它们彼此电绝缘并且确保电极的电活性区域具有正确的尺寸。

公开(公告)号：US07621989B2

公开(公告)日：2009-11-24

申请号：US10542617

申请日：2004-01-20

申请人： Mikael Forslund

发明人： Mikael Forslund

IPC分类号： B01D53/02

CPC分类号： B01J20/28028 ,  B01D39/163 ,  B01D46/0001 ,  B01J47/018

摘要： A pleatable filter structure for use in a filter panel, containing ion exchange particles distributed within a fibrous framework is expanded to contain enough space to allow the ion exchange particles to swell or to be in a swelled state as compared to dry ion exchange particles, without additional expansion of the filter structure. A method of manufacturing the filter structure involves subjecting the filter structure to a moisture treatment in which it is exposed to a humid or water containing environment, whereby the ion exchange particles swell and cause a permanent expansion of the filter structure.

摘要翻译： 包含分布在纤维框架内的离子交换颗粒的过滤面板中的可折叠过滤器结构被扩展以包含足够的空间，以允许离子交换颗粒与干燥的离子交换颗粒相比膨胀或处于溶胀状态，而没有 过滤器结构的额外扩展。 过滤器结构的制造方法包括对过滤器结构进行湿度处理，使其暴露于潮湿或含水环境中，由此离子交换颗粒膨胀并导致过滤器结构的永久膨胀。

公开(公告)号：US08560068B2

公开(公告)日：2013-10-15

申请号：US12808190

申请日：2007-12-18

申请人： Mikael Forslund ,  Johan Eckerdal

发明人： Mikael Forslund ,  Johan Eckerdal

IPC分类号： A61N1/00

CPC分类号： A61N1/0573 ,  A61N1/0587

摘要： An implantable medical system for delivering pacing pulses to HIS bundle of a heart of a patient when implanted in said patient includes a medical lead, which is adapted to be attached with a distal end to tissue of said heart, including a at least two electrodes arranged being electrically separated from each other. The implantable medical device connectable to the medical lead includes a pacing circuit adapted to deliver the pacing pulses to said heart via the medical lead, a selection device connected between the pacing circuit and the electrodes adapted to selectively activate at least one of said electrodes, and a processing device adapted to control the selection device to selectively activate at least one of the electrodes to direct the pacing pulses to the HIS bundle.

摘要翻译： 一种可植入医疗系统，用于在植入患者心脏时向患者的心脏的HIS束输送起搏脉冲包括医用引线，其适于与远端结合到所述心脏的组织，所述远端包括至少两个电极， 彼此电隔离。 可连接到医疗引线的可植入医疗装置包括适于经由医用引线将起搏脉冲输送到心脏的起搏电路，连接在起搏电路和电极之间的选择装置，其适于选择性地激活所述电极中的至少一个，以及 处理装置，其适于控制所述选择装置选择性地激活所述电极中的至少一个以将所述起搏脉冲引导到所述HIS束。

公开(公告)号：US08523588B2

公开(公告)日：2013-09-03

申请号：US13264328

申请日：2009-04-29

申请人： Mikael Forslund ,  Per Jarl ,  Marcus Helgesson

发明人： Mikael Forslund ,  Per Jarl ,  Marcus Helgesson

IPC分类号： H01R13/28

CPC分类号： A61N1/056 ,  H01R24/58 ,  H01R2103/00 ,  H01R2201/12 ,  Y10T29/49208

摘要： An implantable lead has a distal lead portion with at least one electrode electrically connected to a connector ring through a conductor running in a lumen of the lead. A proximal lead portion includes the connector ring, a connector pin and a connector coupling mechanically and coaxially connected to each other with the connector coupling as a bridging element. A rotational lock in the form of a circumferential element of an elastically deformable, flexible material is provided in the connector coupling in the interface between the coupling and the connector ring. This rotational lock prevents any rotation of the connector pin to be propagated into a rotation of the connector coupling and consequently reduces the risk of damages to internal lead components due to any such unintentional coupling rotation.

摘要翻译： 可植入引线具有远端引线部分，其中至少一个电极通过在引线管腔中运行的导体与连接器环电连接。 近端引导部分包括连接器环，连接器引脚和连接器联接器，以连接器联接器作为桥接元件彼此机械地和同轴地连接。 可弹性变形的柔性材料的周向元件形式的旋转锁在耦合器和连接器环之间的接口中设置在连接器联接器中。 该旋转锁定防止连接器销的任何旋转传播到连接器联接器的旋转中，并因此降低由于任何这种无意的联接旋转而损坏内部引线部件的风险。

公开(公告)号：US20130184550A1

公开(公告)日：2013-07-18

申请号：US13825117

申请日：2011-09-19

申请人： Mikael Forslund ,  Andreas Ornberg

发明人： Mikael Forslund ,  Andreas Ornberg

IPC分类号： A61B5/055 ,  A61N1/05 ,  H01F41/06 ,  A61B5/04

CPC分类号： A61B5/055 ,  A61B5/04 ,  A61N1/05 ,  A61N1/056 ,  A61N1/086 ,  H01F41/066 ,  Y10T29/49071

摘要： An implantable medical lead (1) comprises multiple electrodes (22, 24, 26, 28) arranged at a distal end (2), multiple electrode terminals (32, 34, 36, 38) at a proximal end (3) and a lead body (4) with an insulating tubing (40). A conductor coil (10) comprises a coiled tubular insulator (19) having multiple separate lumens (12, 14, 16, 18). Each lumen (12, 14, 16, 18) houses a respective conductor (11, 13, 15, 7), which is movable in the lumen (12, 14, 16, 18) relative the coiled tubular insulator (19). The conductor coil (10) is arranged in a bore (42) of the insulating tubing (40) and each conductor (11, 13, 15, 7) is electrically connected to one of the electrodes (22, 24, 26, 28) and one of the electrode terminals (32, 34, 36, 38).

摘要翻译： 可植入医疗引线（1）包括布置在远端（2）处的多个电极（22,24,26,28），在近端（3）处的多个电极端子（32,34,38）和引线 主体（4）具有绝缘管（40）。 导体线圈（10）包括具有多个独立管腔（12,14,16,18）的螺旋管状绝缘体（19）。 每个管腔（12,14,16,18）容纳相对于螺旋管状绝缘体（19）在管腔（12,14,16,18）中可移动的相应导体（11,13,15,7）。 导体线圈（10）布置在绝缘管（40）的孔（42）中，并且每个导体（11,13,15,7）电连接到一个电极（22,24,26,28） 和电极端子（32,34,36,38）中的一个。