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    Methods, systems, and computer readable media for synthetic wavelength-based phase unwrapping in optical coherence tomography and spectral domain phase microscopy
    3.
    发明授权
    Methods, systems, and computer readable media for synthetic wavelength-based phase unwrapping in optical coherence tomography and spectral domain phase microscopy 有权
    用于光学相干断层扫描和光谱相位显微镜中合成基于波长的相位展开的方法，系统和计算机可读介质

    公开(公告)号：US08565499B2

    公开(公告)日：2013-10-22

    申请号：US12460532

    申请日：2009-07-21

    申请人： Mingtao Zhao ,  Hansford Hendargo ,  Joseph A Izatt

    发明人： Mingtao Zhao ,  Hansford Hendargo ,  Joseph A Izatt

    IPC分类号： G06K9/00 ,  G06K9/40

    CPC分类号： G06T11/003 ,  A61B5/0066 ,  G01N21/4795 ,  G06T3/40

    摘要： In accordance with this disclosure, methods, systems, and computer readable media for synthetic wavelength-based phase unwrapping in optical coherence tomography are provided. Synthetic wavelength phase unwrapping can be applied to OCT data and can correctly resolve sample motions that are larger than λo/2. A method for phase unwrapping of an OCT signal can include acquiring raw OCT signal data, interpolating and processing the OCT signal data to obtain a DC spectrum, comparing the raw OCT signal data to the DC spectrum to generate an interference signal, applying Gaussian windows to the interference signal to generate a two separate signals, extracting phase information from the two signals, and comparing the phase information of the two signals to produce unwrapped phase data. A value of 2π can be added to the phase data if the difference between the phase information of the two signals is less than zero.

    摘要翻译： 根据本公开，提供了用于光学相干断层摄影中的合成基于波长的相位展开的方法，系统和计算机可读介质。 合成波长相位展开可应用于OCT数据，可以正确解析大于lambdao / 2的样本运动。 用于OCT信号的相位展开的方法可以包括获取原始OCT信号数据，内插和处理OCT信号数据以获得DC频谱，将原始OCT信号数据与DC频谱进行比较以产生干扰信号，将高斯窗口应用于 干扰信号以产生两个单独的信号，从两个信号中提取相位信息，并比较两个信号的相位信息以产生展开的相位数据。 如果两个信号的相位信息之间的差小于零，则可以向相位数据添加2pi的值。

    Methods and computer program products for quantitative three-dimensional image correction and clinical parameter computation in optical coherence tomography
    4.
    发明申请
    Methods and computer program products for quantitative three-dimensional image correction and clinical parameter computation in optical coherence tomography 有权
    光学相干断层扫描中定量三维图像校正和临床参数计算的方法和计算机程序产品

    公开(公告)号：US20110032533A1

    公开(公告)日：2011-02-10

    申请号：US12799890

    申请日：2010-05-04

    申请人： Joseph A. Izatt ,  Mingtao Zhao ,  Anthony N. Kuo

    发明人： Joseph A. Izatt ,  Mingtao Zhao ,  Anthony N. Kuo

    IPC分类号： G01B11/02

    CPC分类号： G06T15/00 ,  A61B3/102 ,  G01B9/02083 ,  G01B9/02091 ,  G01B11/2441 ,  G06F19/00 ,  G06T5/006 ,  G06T2207/10101 ,  G06T2207/30041

    摘要： Methods and computer program products for quantitative three-dimensional (“3D”) image correction in optical coherence tomography. Using the methods and computer program products, index interface (refracting) surfaces from the raw optical coherence tomography (“OCT”) dataset from an OCT system can be segmented. Normal vectors or partial derivatives of the curvature at a refracting surface can be calculated to obtain a refracted image voxel. A new position of each desired refracted image voxel can be iteratively computed. New refracted corrected voxel positions to an even sampling grid can be interpolated to provide corrected image data. In some embodiments, clinical outputs from the corrected image data can be computed.

    摘要翻译： 光学相干断层扫描中定量三维（“3D”）图像校正的方法和计算机程序产品。 使用方法和计算机程序产品，可以对来自OCT系统的原始光学相干断层扫描（“OCT”）数据集的索引接口（折射）表面进行分割。 可以计算折射表面处的曲率的法向矢量或偏导数，以获得折射的图像体素。 可以迭代地计算每个期望的折射图像体素的新位置。 可以将针对均匀采样网格的新的折射校正体素位置进行内插以提供校正的图像数据。 在一些实施例中，可以计算来自校正图像数据的临床输出。

    Methods, systems, and computer readable media for synthetic wavelength-based phase unwrapping in optical coherence tomography and spectral domain phase microscopy
    6.
    发明申请
    Methods, systems, and computer readable media for synthetic wavelength-based phase unwrapping in optical coherence tomography and spectral domain phase microscopy 有权
    用于光学相干断层扫描和光谱相位显微镜中合成基于波长的相位展开的方法，系统和计算机可读介质

    公开(公告)号：US20100150467A1

    公开(公告)日：2010-06-17

    申请号：US12460532

    申请日：2009-07-21

    申请人： Mingtao Zhao ,  Hansford Hendargo ,  Joesph A. Izatt

    发明人： Mingtao Zhao ,  Hansford Hendargo ,  Joesph A. Izatt

    IPC分类号： G06K9/40 ,  G06K9/32

    CPC分类号： G06T11/003 ,  A61B5/0066 ,  G01N21/4795 ,  G06T3/40

    摘要： In accordance with this disclosure, methods, systems, and computer readable media for synthetic wavelength-based phase unwrapping in optical coherence tomography are provided. Synthetic wavelength phase unwrapping can be applied to OCT data and can correctly resolve sample motions that are larger than λo/2. A method for phase unwrapping of an OCT signal can include acquiring raw OCT signal data, interpolating and processing the OCT signal data to obtain a DC spectrum, comparing the raw OCT signal data to the DC spectrum to generate an interference signal, applying Gaussian windows to the interference signal to generate a two separate signals, extracting phase information from the two signals, and comparing the phase information of the two signals to produce unwrapped phase data. A value of 2π can be added to the phase data if the difference between the phase information of the two signals is less than zero.

    摘要翻译： 根据本公开，提供了用于光学相干断层摄影中的合成基于波长的相位展开的方法，系统和计算机可读介质。 合成波长相位展开可应用于OCT数据，可正确解析大于λo/ 2的样品运动。 用于OCT信号的相位展开的方法可以包括获取原始OCT信号数据，内插和处理OCT信号数据以获得DC频谱，将原始OCT信号数据与DC频谱进行比较以产生干扰信号，将高斯窗口应用于 干扰信号以产生两个单独的信号，从两个信号中提取相位信息，并比较两个信号的相位信息以产生展开的相位数据。 值为2＆pgr; 如果两个信号的相位信息之间的差小于零，则可将其加到相位数据中。