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    Super paramagnetic iron oxide nanoparticles with metallic coatings and a method of synthesizing the same
    1.
    发明授权
    Super paramagnetic iron oxide nanoparticles with metallic coatings and a method of synthesizing the same 有权
    具有金属涂层的超顺磁性氧化铁纳米粒子及其合成方法

    公开(公告)号：US08962031B2

    公开(公告)日：2015-02-24

    申请号：US13771479

    申请日：2013-02-20

    申请人： Morteza Mahmoudi ,  Mohammad Ali Shokrgozar ,  Pasteur Institute of Iran

    发明人： Morteza Mahmoudi ,  Mohammad Ali Shokrgozar

    IPC分类号： A61K9/14 ,  A61K9/16 ,  B05D7/00

    CPC分类号： A61K9/14 ,  A61K9/5146 ,  A61K9/5161 ,  A61K33/24 ,  A61K33/38

    摘要： The various embodiments herein provide super paramagnetic iron oxide nanoparticles (SPIONs). The SPIONs have a plurality of metallic coatings and plurality of polymeric gaps. The embodiments herein also provide a method of synthesizing the SPIONs with metallic rings and polymeric gaps. The metallic coatings form a ring like structure on the outer surface of the SPION. The SPION has a size of 13 nm. The ring has a thickness of 2-3 nm. The rings are one or more in number. The polymeric gaps have a thickness of 3-5 nm. The polymeric gaps are one or more in number. The method involves mixing the SPIONs with a plurality of polymers and then forming a metallic ring on the outer surface of the SPIONs. The SPIONs have anti-bacterial properties and stop a growth of bacterial biofilms. The SPIONs also have SERS properties.

    摘要翻译： 本文的各种实施方案提供超顺磁性氧化铁纳米粒子（SPION）。 SPION具有多个金属涂层和多个聚合间隙。 本文的实施方案还提供了一种用金属环和聚合物间隙合成SPION的方法。 金属涂层在SPION的外表面上形成环状结构。 SPION的尺寸为13 nm。 该环的厚度为2-3nm。 戒指是一个或多个戒指。 聚合物间隙的厚度为3-5nm。 聚合物间隙是数量中的一个或多个。 该方法包括将SPION与多种聚合物混合，然后在SPION的外表面上形成金属环。 SPIONs具有抗细菌特性，阻止细菌生物膜的生长。 SPION还具有SERS属性。

    PLASMONIC STABLE FLUORESCENCE SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES AND A METHOD OF SYNTHESIZING THE SAME
    4.
    发明申请
    PLASMONIC STABLE FLUORESCENCE SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES AND A METHOD OF SYNTHESIZING THE SAME 审中-公开
    等离子体稳定荧光超级磁铁氧化物纳米颗粒及其合成方法

    公开(公告)号：US20140234226A1

    公开(公告)日：2014-08-21

    申请号：US14270879

    申请日：2014-05-06

    申请人： Morteza Mahmoudi ,  Mohammad Ali Shokrgozar

    发明人： Morteza Mahmoudi ,  Mohammad Ali Shokrgozar

    IPC分类号： A61K49/18

    CPC分类号： A61K49/1863

    摘要： The various embodiments herein provide for the engineered multimodal super paramagnetic iron oxide nanoparticles (SPIONs) with a fluorescent dye. The SPIONs comprise fluorescent polymer dye arranged in a gap between a SPION core and a gold shell. The SPIONS are provided with a gold coating. The gap is made up of a polymeric molecule such as 6-arm anthracene terminated. The core of the nanoparticle is made up of a magnetic metal oxide. The method for synthesizing SPIONs involves preparing carboxyl-dextran complex and the SPIONS. The SPIONs are coated with carboxyl-dextran complex. The coated SPIONs coated are subjected to fluorescent polymer and gold nano shell coating. The prepared SPIONs are characterized by light scattering measurement and magnetization measurements.

    摘要翻译： 本文的各种实施方案提供具有荧光染料的工程多模超顺磁性氧化铁纳米颗粒（SPION）。 SPION包括布置在SPION芯和金壳之间的间隙中的荧光聚合物染料。 SPIONS配有镀金涂层。 间隙由诸如6-臂蒽末端的聚合物分子组成。 纳米颗粒的核心由磁性金属氧化物组成。 合成SPION的方法包括制备羧基葡聚糖复合物和SPIONS。 SPIONs涂有羧基葡聚糖复合物。 涂覆的涂覆的SPIONs经受荧光聚合物和金纳米壳涂层。 制备的SPION的特征在于光散射测量和磁化测量。