Pharmaceutical composition and therapeutic method
    2.
    发明申请
    Pharmaceutical composition and therapeutic method 审中-公开
    药物组成及治疗方法

    公开(公告)号:US20090016987A1

    公开(公告)日:2009-01-15

    申请号:US11596674

    申请日:2005-05-17

    IPC分类号: C07K14/54 A61K38/21 A61P29/00

    摘要: The object of the present invention is, based on the finding of a novel effect of IL-18, to provide pharmaceutical compositions containing IL-18 and therapeutic methods, for preventing, improving, or treating inflammatory diseases such as systemic inflammatory response syndrome (SIRS). Inflammatory diseases, such as SIRS, can be prevented, improved, or treated by administering the pharmaceutical compositions according to the present invention containing IL-18 in an amount which does not bring the decreased interleukin 18 level in either plasma or liver to a higher level than normal.

    摘要翻译: 本发明的目的是基于IL-18的新作用的发现,提供含有IL-18的药物组合物和治疗方法,用于预防,改善或治疗诸如全身炎症反应综合征(SIRS) )。 可以通过给予含有IL-18的本发明的药物组合物来防止,改善或治疗炎性疾病,其量不会使血浆或肝脏中的白介素18水平降低到更高的水平 比正常