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    Device and method for high intensity focused ultrasound ablation with acoustic lens
    1.
    发明授权
    Device and method for high intensity focused ultrasound ablation with acoustic lens 有权
    声透镜高强度聚焦超声消融的装置和方法

    公开(公告)号：US08382689B2

    公开(公告)日：2013-02-26

    申请号：US11703783

    申请日：2007-02-08

    申请人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    发明人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    IPC分类号： A61H1/00

    CPC分类号： A61N7/02 ,  A61N2007/0056 ,  A61N2007/006 ,  A61N2007/0078

    摘要： A high intensity focused ultrasound transducer includes an ultrasonic emitter having a surface that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens acoustically coupled to the surface in the beam path of the ultrasonic energy, such that the lens can direct the ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf, a heat sink, or an acoustic matching layer, to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, the first surface is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the first ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.

    摘要翻译： 高强度聚焦超声换能器包括具有沿着光束路径发射超声波能量的表面的超声波发射器，至少一个低衰减聚合物超声波透镜，声学耦合到超声能量的光束路径中的表面，使得透镜可以直接 在至少一个方向上的超声波能量，以及至少一个应力消除特征，例如切口，散热器或声匹配层，以减轻换能器内的热膨胀失配应力。 为了制造简单，第一表面通常是平坦的或单调曲线的。 透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。 考虑到相对于第一超声波发射器的至少一个超声波透镜的任何取向和定位。 通过模制，铸造或热成型镜片进一步简化制造。

    High intensity focused ultrasound transducer with acoustic lens
    2.
    发明授权
    High intensity focused ultrasound transducer with acoustic lens 有权
    高强度聚焦超声波换能器与声透镜

    公开(公告)号：US08102734B2

    公开(公告)日：2012-01-24

    申请号：US11703784

    申请日：2007-02-08

    申请人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    发明人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    IPC分类号： A61B8/00

    CPC分类号： A61N7/02 ,  A61B8/4272 ,  A61B17/2251

    摘要： A high intensity focused ultrasound transducer includes an ultrasonic emitter having a surface that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens acoustically coupled to the surface in the beam path of the ultrasonic energy, such that the lens can direct the ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf, a heat sink, or an acoustic matching layer, to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, the first surface is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the first ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.

    摘要翻译： 高强度聚焦超声换能器包括具有沿着光束路径发射超声波能量的表面的超声波发射器，至少一个低衰减聚合物超声波透镜，声学耦合到超声能量的光束路径中的表面，使得透镜可以直接 在至少一个方向上的超声波能量，以及至少一个应力消除特征，例如切口，散热器或声匹配层，以减轻换能器内的热膨胀失配应力。 为了制造简单，第一表面通常是平坦的或单调曲线的。 透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。 考虑到相对于第一超声波发射器的至少一个超声波透镜的任何取向和定位。 通过模制，铸造或热成型镜片进一步简化制造。

    High intensity focused ultrasound transducer with acoustic lens
    3.
    发明申请
    High intensity focused ultrasound transducer with acoustic lens 有权
    高强度聚焦超声波换能器与声透镜

    公开(公告)号：US20080194967A1

    公开(公告)日：2008-08-14

    申请号：US11703784

    申请日：2007-02-08

    申请人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    发明人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    IPC分类号： A61B8/00

    CPC分类号： A61N7/02 ,  A61B8/4272 ,  A61B17/2251

    摘要： A high intensity focused ultrasound transducer includes an ultrasonic emitter having a surface that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens acoustically coupled to the surface in the beam path of the ultrasonic energy, such that the lens can direct the ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf, a heat sink, or an acoustic matching layer, to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, the first surface is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the first ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.

    摘要翻译： 高强度聚焦超声换能器包括具有沿着光束路径发射超声波能量的表面的超声波发射器，至少一个低衰减聚合物超声波透镜，声学耦合到超声能量的光束路径中的表面，使得透镜可以直接 在至少一个方向上的超声波能量，以及至少一个应力消除特征，例如切口，散热器或声匹配层，以减轻换能器内的热膨胀失配应力。 为了制造简单，第一表面通常是平坦的或单调曲线的。 透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。 考虑到相对于第一超声波发射器的至少一个超声波透镜的任何取向和定位。 通过模制，铸造或热成型镜片进一步简化制造。

    Apparatus for contacting foil conductors, in particular of a solar module
    4.
    发明授权
    Apparatus for contacting foil conductors, in particular of a solar module 有权
    用于接触箔导体，特别是太阳能模块的装置

    公开(公告)号：US06582249B1

    公开(公告)日：2003-06-24

    申请号：US09715590

    申请日：2000-11-17

    申请人： Werner Boeck ,  Klaus-Peter Goetz ,  Guenter Feldmeier ,  Heinz Scherer ,  Martin Szelag ,  Andreas Woeber

    发明人： Werner Boeck ,  Klaus-Peter Goetz ,  Guenter Feldmeier ,  Heinz Scherer ,  Martin Szelag ,  Andreas Woeber

    IPC分类号： H01R1224

    CPC分类号： H01R12/62 ,  H01R13/5208 ,  H02S40/34 ,  Y10S439/936

    摘要： An apparatus for making contact with a foil conductor, in particular of a solar module, the apparatus having a housing, a first connecting region for connecting to the foil conductor, and a second connecting region with at least one contact for connecting at least one plug connector. At least one conductor rail connects the contact to the foil conductor. The conductor rail has a contact region for detachable connection to the foil conductor. The conductor rail has a terminal area for receiving electronic modules, for example a diode or lead portions. Each conductor rail is connected to the contact of the second connecting region.

    摘要翻译： 一种用于与箔导体（特别是太阳能模块）接触的装置，该装置具有壳体，用于连接到箔导体的第一连接区域和具有至少一个触点的第二连接区域，用于连接至少一个插头 连接器。 至少一个导轨将触点连接到箔导体。 导轨具有用于可拆卸地连接到箔导体的接触区域。 导体导轨具有用于接收电子模块的端子区域，例如二极管或引线部分。 每个导轨连接到第二连接区域的触点。

    Device and method for high intensity focused ultrasound ablation with acoustic lens
    7.
    发明申请
    Device and method for high intensity focused ultrasound ablation with acoustic lens 有权
    声透镜高强度聚焦超声消融的装置和方法

    公开(公告)号：US20080194965A1

    公开(公告)日：2008-08-14

    申请号：US11703783

    申请日：2007-02-08

    申请人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    发明人： John W. Sliwa ,  Peter Goetz ,  Zhenyi Ma ,  Jennifer Teng ,  Stephen Morse ,  Frank Callaghan ,  Timothy E. Ciciarelli

    IPC分类号： A61B17/00

    CPC分类号： A61N7/02 ,  A61N2007/0056 ,  A61N2007/006 ,  A61N2007/0078

    摘要： A high intensity focused ultrasound transducer includes an ultrasonic emitter having a surface that emits ultrasonic energy along a beam path, at least one low attenuation polymeric ultrasonic lens acoustically coupled to the surface in the beam path of the ultrasonic energy, such that the lens can direct the ultrasonic energy in at least one direction, and at least one stress mitigation feature, such as a kerf, a heat sink, or an acoustic matching layer, to mitigate thermal expansion mismatch stresses within the transducer. For manufacturing simplicity, the first surface is typically either flat or monotonically curvilinear. The lens may take a variety of shapes, including Fresnel features, and may focus, collimate, or defocus the ultrasonic energy. Any orientation and positioning of the at least one ultrasonic lens relative to the first ultrasonic emitter is contemplated. Manufacture is further simplified by molding, casting, or thermoforming the lens.

    摘要翻译： 高强度聚焦超声换能器包括具有沿着光束路径发射超声波能量的表面的超声波发射器，至少一个低衰减聚合物超声波透镜，声学耦合到超声能量的光束路径中的表面，使得透镜可以直接 在至少一个方向上的超声波能量，以及至少一个应力消除特征，例如切口，散热器或声匹配层，以减轻换能器内的热膨胀失配应力。 为了制造简单，第一表面通常是平坦的或单调曲线的。 透镜可以采取各种形状，包括菲涅尔特征，并且可以聚焦，准直或散焦超声能量。 考虑到相对于第一超声波发射器的至少一个超声波透镜的任何取向和定位。 通过模制，铸造或热成型镜片进一步简化制造。

    LINE MARKING ASSEMBLY
    8.
    发明申请
    LINE MARKING ASSEMBLY 有权
    线路标线装配

    公开(公告)号：US20130019487A1

    公开(公告)日：2013-01-24

    申请号：US13550475

    申请日：2012-07-16

    申请人： Keith Gerard Fritsch ,  Herbert John Peter Goetz ,  Mark S. Payne

    发明人： Keith Gerard Fritsch ,  Herbert John Peter Goetz ,  Mark S. Payne

    IPC分类号： B44D3/38

    CPC分类号： B44D3/38

    摘要： A line marking assembly for applying a marking a straight line with a marking powder onto a surface is disclosed. The line marking assembly comprises two chambers configured to mount one on each side of a level. Each chamber contains a cord wound on a spool, marking powder and a tensioning assembly that exerts a constant and continuous pull on the cord. The cords from each of the chambers may be combined with a coupler. Moving the coupler back and forth between the chambers coats the cords with marking powder. Placing the assembly onto a surface and snapping the cord marks a straight line on the surface.

    摘要翻译： 公开了一种用于将具有标记粉末的直线标记施加到表面上的线标记组件。 线标记组件包括被配置成在水平面的每一侧安装一个的两个室。 每个室包含缠绕在卷轴上的绳索，标记粉末和张紧组件，其在绳索上施加恒定且连续的拉力。 来自每个室的帘线可以与耦合器组合。 在两个室之间来回移动耦合器，用标记粉末涂覆电线。 将组件放置在表面上并扣住绳索在表面上标记直线。

    NATURAL MICROORGANISMS WHICH ARE NATURALLY CAPABLE OF BINDING TOXINS AND/OR TOXIN RECEPTORS
    10.
    发明申请
    NATURAL MICROORGANISMS WHICH ARE NATURALLY CAPABLE OF BINDING TOXINS AND/OR TOXIN RECEPTORS 审中-公开

    公开(公告)号：US20190257832A1

    公开(公告)日：2019-08-22

    申请号：US16318532

    申请日：2017-07-18

    申请人： Philippe ULSEMER ,  Steffen GOLETZ ,  Peter GOETZ

    发明人： Philippe ULSEMER ,  Steffen GOLETZ ,  Peter GOETZ

    IPC分类号： G01N33/569 ,  C12N1/16 ,  C12N1/20 ,  A61P1/00 ,  A61K35/74

    摘要： The present invention relates to means and method for isolating naturally-occurring microorganisms (non-pathogenic bacteria, yeasts or fungi) capable of binding toxins from microorganisms such as bacteria, viruses, fungi, yeasts, or protozoans and/or receptors for these toxins on the surface of mammalian cells, thereby making these receptors inaccessible for said toxins. The naturally-occurring microorganisms that are obtainable by the means and methods of the present invention can be used for adsorbing toxins from pathogenic microorganisms and/or blocking receptors for such toxins on the surface of mammalian cells. These toxin-receptor interactions are known to be critical for disease pathogenesis, making both the toxins and receptors a target for the naturally-occurring microorganisms of the present invention.