公开(公告)号：US6121410A

公开(公告)日：2000-09-19

申请号：US361375

申请日：1999-07-27

Applicant: Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Christopher M. Ryan ,  Eric Stanley Hall ,  Robin Sue Eichen Conn

Inventor： Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Christopher M. Ryan ,  Eric Stanley Hall ,  Robin Sue Eichen Conn

IPC: C08K3/16 ,  A61L15/26 ,  A61L31/06 ,  C08G63/08 ,  C08G63/88 ,  C08G63/90 ,  C08J5/18 ,  C08K3/22 ,  C08K3/26 ,  C08K3/30 ,  C08K3/34 ,  C08K5/10 ,  C08K5/13 ,  C08K5/1515 ,  C08K5/1575 ,  C08K5/29 ,  C08K5/51 ,  C08K5/524 ,  C08K5/54 ,  C08L67/00 ,  C08L67/04 ,  C08L101/00 ,  C08L101/16 ,  C09D167/04 ,  D01F6/62 ,  D04H1/42 ,  D21H19/28 ,  D21H19/62 ,  B32B9/04 ,  B32B27/36

CPC classification number: C08J5/18 ,  A61L15/26 ,  A61L31/06 ,  C08G63/08 ,  C08G63/90 ,  C08L67/04 ,  C09D167/04 ,  D01F6/625 ,  D04H1/42 ,  D21H19/28 ,  D21H19/62 ,  C08G2230/00 ,  C08J2367/04 ,  C08L101/00

Abstract: A semi-crystalline film comprised of a lactide polymer. The lactide polymer comprises a plurality of poly(lactide) polymer chains, residual lactide in concentration of less than about 5 percent and water in concentration of less than about 2000 parts-per-million. A process for manufacturing a semi-crystalline film with the lactide polymer composition is also disclosed.

公开(公告)号：US6005068A

公开(公告)日：1999-12-21

申请号：US119487

申请日：1998-07-20

Applicant: Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Christopher M. Ryan ,  Eric Stanley Hall ,  Robin Sue Eichen Conn

Inventor： Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Christopher M. Ryan ,  Eric Stanley Hall ,  Robin Sue Eichen Conn

IPC: A61L15/26 ,  A61L31/06 ,  C08G63/08 ,  C08G63/90 ,  C08J5/18 ,  C08L67/04 ,  C08L101/00 ,  C09D167/04 ,  D01F6/62 ,  D04H1/42 ,  D21H19/28 ,  D21H19/62

CPC classification number: C08J5/18 ,  A61L15/26 ,  A61L31/06 ,  C08G63/08 ,  C08G63/90 ,  C08L67/04 ,  C09D167/04 ,  D01F6/625 ,  D04H1/42 ,  D21H19/28 ,  D21H19/62 ,  C08G2230/00 ,  C08J2367/04 ,  C08L101/00 ,  Y10T428/249921 ,  Y10T428/25 ,  Y10T428/252 ,  Y10T428/253 ,  Y10T428/257 ,  Y10T428/259 ,  Y10T428/268 ,  Y10T428/31504 ,  Y10T428/31786

Abstract: An amorphous film comprised of a lactide polymer. The lactide polymer comprises a plurality of poly(lactide) polymer chains, residual lactide in concentration of less than about 2 percent and water in concentration of less than about 2000 parts-per-million. A process for manufacturing an amorphous film with the lactide polymer composition is also disclosed.

Abstract translation: 由丙交酯聚合物构成的无定形膜。 丙交酯聚合物包含多个聚（丙交酯）聚合物链，浓度小于约2％的残余丙交酯和浓度小于约2000ppm的水。 还公开了用丙交酯聚合物组合物制造非晶膜的方法。

公开(公告)号：US5981694A

公开(公告)日：1999-11-09

申请号：US966111

申请日：1997-11-07

Applicant: Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Eric Stanley Hall ,  Robin Sue Eichen Conn ,  Christopher M. Ryan

Inventor： Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Eric Stanley Hall ,  Robin Sue Eichen Conn ,  Christopher M. Ryan

IPC: C08K3/16 ,  A61L15/26 ,  A61L31/06 ,  C08G63/08 ,  C08G63/88 ,  C08G63/90 ,  C08J5/18 ,  C08K3/22 ,  C08K3/26 ,  C08K3/30 ,  C08K3/34 ,  C08K5/10 ,  C08K5/13 ,  C08K5/1515 ,  C08K5/1575 ,  C08K5/29 ,  C08K5/51 ,  C08K5/524 ,  C08K5/54 ,  C08L67/00 ,  C08L67/04 ,  C08L101/00 ,  C08L101/16 ,  C09D167/04 ,  D01F6/62 ,  D04H1/42 ,  D21H19/28 ,  D21H19/62

CPC classification number: C08J5/18 ,  A61L15/26 ,  A61L31/06 ,  C08G63/08 ,  C08G63/90 ,  C08L67/04 ,  C09D167/04 ,  D01F6/625 ,  D04H1/42 ,  D21H19/28 ,  D21H19/62 ,  C08G2230/00 ,  C08J2367/04 ,  C08L101/00 ,  Y10T428/31504 ,  Y10T428/31786 ,  Y10T428/3179 ,  Y10T428/31808 ,  Y10T428/31819 ,  Y10T428/31993

Abstract: A lactide polymer composition combining compositional and purity limitations and catalyst optimization or addition of stabilizing agents resulting in a melt-stable polymer is disclosed. The melt-stable lactide polymer comprises a plurality of polylactide polymer chains, residual lactide in concentration of less than 2 percent and water in concentration of less than 1000 parts-per-million. A stabilizing agent in an amount sufficient to reduce depolymerization of the lactide polymer during melt-processing or alternatively, control of catalyst level at a molar ratio of monomer to catalyst greater than 3000:1 is also included in the melt-stable composition. A process for manufacture of a melt-stable lactide polymer composition includes polymerizing a lactide mixture and adding stabilizing agents sufficient to reduce depolymerization of the polylactide during melt-processing, followed by devolatilizing the polylactide to remove monomer and water.

公开(公告)号：US5798436A

公开(公告)日：1998-08-25

申请号：US708321

申请日：1996-09-05

Applicant: Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Christopher M. Ryan ,  Eric Stanley Hall ,  Robin Sue Eichen Conn

Inventor： Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Christopher M. Ryan ,  Eric Stanley Hall ,  Robin Sue Eichen Conn

IPC: C08K3/16 ,  A61L15/26 ,  A61L31/06 ,  C08G63/08 ,  C08G63/88 ,  C08G63/90 ,  C08J5/18 ,  C08K3/22 ,  C08K3/26 ,  C08K3/30 ,  C08K3/34 ,  C08K5/10 ,  C08K5/13 ,  C08K5/1515 ,  C08K5/1575 ,  C08K5/29 ,  C08K5/51 ,  C08K5/524 ,  C08K5/54 ,  C08L67/00 ,  C08L67/04 ,  C08L101/00 ,  C08L101/16 ,  C09D167/04 ,  D01F6/62 ,  D04H1/42 ,  D21H19/28 ,  D21H19/62

CPC classification number: C08J5/18 ,  A61L15/26 ,  A61L31/06 ,  C08G63/08 ,  C08G63/90 ,  C08L67/04 ,  C09D167/04 ,  D01F6/625 ,  D04H1/42 ,  D21H19/28 ,  D21H19/62 ,  C08G2230/00 ,  C08J2367/04 ,  C08L101/00 ,  Y10T428/31504 ,  Y10T428/31786 ,  Y10T428/3179 ,  Y10T428/31808 ,  Y10T428/31819 ,  Y10T428/31993

Abstract: An amorphous film comprised of a lactide polymer. The lactide polymer comprises a plurality of poly(lactide) polymer chains, residual lactide in concentration of less than about 2 percent and water in concentration of less than about 2000 parts-per-million. A process for manufacturing an amorphous film with the lactide polymer composition is also disclosed.

公开(公告)号：US06326458B1

公开(公告)日：2001-12-04

申请号：US08133445

申请日：1993-10-07

Applicant: Patrick Richard Gruber ,  Eric Stanley Hall ,  Jeffrey John Kolstad ,  Matthew Lee Iwen ,  Richard Douglas Benson ,  Ronald Leo Borchardt

Inventor： Patrick Richard Gruber ,  Eric Stanley Hall ,  Jeffrey John Kolstad ,  Matthew Lee Iwen ,  Richard Douglas Benson ,  Ronald Leo Borchardt

IPC: C08G6308

CPC classification number: C08G63/08 ,  C07D319/12 ,  C08G63/06

Abstract: A process for the continuous production of substantially purified lactide and lactide polymers from lactic acid or an ester of lactic acid including the steps of forming crude polylactic acid, preferably in the presence of a catalyst means in the case of the ester of lactic acid, to form a condensation reaction by-product and polylactic acid, and depolymerizing the polylactic acid in a lactide reactor to form crude lactide, followed by subsequent purification of the crude lactide in a distillation system. A purified lactide is then polymerized to form lactide polymers.

Abstract translation: 从乳酸或乳酸酯连续生产基本上纯化的丙交酯和丙交酯聚合物的方法，包括以下步骤：优选在乳酸酯的情况下，在催化剂存在下，形成粗乳酸， 形成缩合反应副产物和聚乳酸，并将聚乳酸在丙交酯反应器中解聚以形成粗丙交酯，随后在蒸馏系统中纯化粗丙交酯。 然后将纯化的丙交酯聚合以形成丙交酯聚合物。

公开(公告)号：US6143863A

公开(公告)日：2000-11-07

申请号：US309853

申请日：1999-05-11

Applicant: Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Eric Stanley Hall ,  Robin Sue Eichen Conn ,  Christopher M. Ryan

Inventor： Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Eric Stanley Hall ,  Robin Sue Eichen Conn ,  Christopher M. Ryan

IPC: C08K3/16 ,  A61L15/26 ,  A61L31/06 ,  C08G63/08 ,  C08G63/88 ,  C08G63/90 ,  C08J5/18 ,  C08K3/22 ,  C08K3/26 ,  C08K3/30 ,  C08K3/34 ,  C08K5/10 ,  C08K5/13 ,  C08K5/1515 ,  C08K5/1575 ,  C08K5/29 ,  C08K5/51 ,  C08K5/524 ,  C08K5/54 ,  C08L67/00 ,  C08L67/04 ,  C08L101/00 ,  C08L101/16 ,  C09D167/04 ,  D01F6/62 ,  D04H1/42 ,  D21H19/28 ,  D21H19/62

CPC classification number: C08J5/18 ,  A61L15/26 ,  A61L31/06 ,  C08G63/08 ,  C08G63/90 ,  C08L67/04 ,  C09D167/04 ,  D01F6/625 ,  D04H1/42 ,  D21H19/28 ,  D21H19/62 ,  C08G2230/00 ,  C08J2367/04 ,  C08L101/00

Abstract: A lactide polymer composition combining compositional and purity limitations and catalyst optimization or addition of stabilizing agents resulting in a melt-stable polymer is disclosed. The melt-stable lactide polymer comprises a plurality of polylactide polymer chains, residual lactide in concentration of less than 2 percent and water in concentration of less than 1000 parts-per-million. A stabilizing agent in an amount sufficient to reduce depolymerization of the lactide polymer during melt-processing or alternatively, control of catalyst level at a molar ratio of monomer to catalyst greater than 3000:1 is also included in the melt-stable composition. A process for manufacture of a melt-stable lactide polymer composition includes polymerizing a lactide mixture and adding stabilizing agents sufficient to reduce depolymerization of the polylactide during melt-processing, followed by devolatilizing the polylactide to remove monomer and water.

Abstract translation: 公开了结合组合和纯度限制和催化剂优化或添加产生熔融稳定聚合物的稳定剂的丙交酯聚合物组合物。 熔融稳定的丙交酯聚合物包含多个聚丙交酯聚合物链，浓度小于2％的残余丙交酯和浓度小于1000ppm的水。 在熔融加工过程中足以减少丙交酯聚合物解聚的稳定剂，或者以单体与催化剂的摩尔比大于3000:1的催化剂含量的控制也包括在熔融稳定组合物中。 制备熔融稳定的丙交酯聚合物组合物的方法包括聚合丙交酯混合物并加入足以在熔融加工期间减少聚丙交酯的解聚的稳定剂，然后使聚交酯脱挥发去除单体和水。

公开(公告)号：US5798435A

公开(公告)日：1998-08-25

申请号：US707245

申请日：1996-09-03

Applicant: Patrick Richard Gruber ,  Jeffrey John Kolstad ,  David Roy Witzke ,  Mark Henry Hartmann ,  Andrea Lee Brosch

Inventor： Patrick Richard Gruber ,  Jeffrey John Kolstad ,  David Roy Witzke ,  Mark Henry Hartmann ,  Andrea Lee Brosch

IPC: A61F13/15 ,  A61F13/49 ,  A61F13/551 ,  B29C45/00 ,  B29C49/00 ,  B29C51/00 ,  B29K67/00 ,  C08F290/00 ,  C08F299/04 ,  C08G18/42 ,  C08G59/40 ,  C08G63/08 ,  C08G63/78 ,  C08G63/91 ,  C08J3/24 ,  C08J5/18 ,  C08L67/04 ,  D04H1/42 ,  D21H19/24

CPC classification number: C08G63/08 ,  Y10T428/31786 ,  Y10T428/3179 ,  Y10T442/60

Abstract: A composition comprising a polylactide polymer with improved extensional viscosity and methods of making the same are disclosed. The polylactide polymer composition is prepared by providing in the composition polylactide polymer molecules which have been modified, relative to linear non-substituted polylactide, to provide increased molecular interaction among polylactide backbone chains in the composition. The preferred polylactide polymer composition has a number average molecular weight of at least about 10,000 (preferably at least 50,000) and a polydispersity of at least about 2.5. In addition, the polylactide polymer composition should have a neck-in ratio of less than about 0.8.

公开(公告)号：US06291597B1

公开(公告)日：2001-09-18

申请号：US09400616

申请日：1999-09-20

Applicant: Patrick Richard Gruber ,  Jeffrey John Kolstad ,  David Roy Witzke ,  Mark Henry Hartmann ,  Andrea Lee Brosch

Inventor： Patrick Richard Gruber ,  Jeffrey John Kolstad ,  David Roy Witzke ,  Mark Henry Hartmann ,  Andrea Lee Brosch

IPC: C08G6308

CPC classification number: C08G63/08 ,  Y10T428/31786 ,  Y10T428/3179 ,  Y10T442/60

Abstract: A composition comprising a polylactide polymer with improved extensional viscosity and methods of making the same are disclosed. The polylactide polymer composition is prepared by providing in the composition polylactide polymer molecules which have been modified, relative to linear non-substituted polylactide, to provide increased molecular interaction among polylactide backbone chains in the composition. The preferred polylactide polymer composition has a number average molecular weight of at least about 10,000 (preferably at least 50,000) and a polydispersity of at least about 2.5. In addition, the polylactide polymer composition should have a neck-in ratio of less than about 0.8.

Abstract translation: 公开了包含具有改进的拉伸粘度的聚丙交酯聚合物的组合物及其制备方法。 聚丙交酯聚合物组合物通过在组合物中提供相对于线性未取代的聚交酯改性的聚丙交酯聚合物分子来制备，以在组合物中的聚交酯骨架链之间提供增加的分子相互作用。 优选的聚丙交酯聚合物组合物具有至少约10,000（优选至少50,000）的数均分子量和至多约2.5的多分散性。 另外，聚丙交酯聚合物组合物的颈缩比应小于约0.8。

公开(公告)号：US06207792B1

公开(公告)日：2001-03-27

申请号：US09361538

申请日：1999-07-27

Applicant: Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Christopher M. Ryan ,  Eric Stanley Hall ,  Robin Sue Eichen Conn

Inventor： Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Christopher M. Ryan ,  Eric Stanley Hall ,  Robin Sue Eichen Conn

IPC: C08G6308

CPC classification number: C08J5/18 ,  A61L15/26 ,  A61L31/06 ,  C08G63/08 ,  C08G63/90 ,  C08G2230/00 ,  C08J2367/04 ,  C08L67/04 ,  C08L101/00 ,  C09D167/04 ,  D01F6/625 ,  D04H1/42 ,  D21H19/28 ,  D21H19/62 ,  Y10T428/249921 ,  Y10T428/25 ,  Y10T428/252 ,  Y10T428/253 ,  Y10T428/257 ,  Y10T428/259 ,  Y10T428/268 ,  Y10T428/31504 ,  Y10T428/31786 ,  C08L2666/02

Abstract: An amorphous film comprised of a lactide polymer. The lactide polymer comprises a plurality of poly(lactide) polymer chains, residual lactide in concentration of less than about 2 percent and water in concentration of less than about 2000 parts-per-million. A process for manufacturing an amorphous film with the lactide polymer composition is also disclosed.

Abstract translation: 由丙交酯聚合物构成的无定形膜。 丙交酯聚合物包含多个聚（丙交酯）聚合物链，浓度小于约2％的残余丙交酯和浓度小于约2000ppm的水。 还公开了用丙交酯聚合物组合物制造非晶膜的方法。

公开(公告)号：US6093791A

公开(公告)日：2000-07-25

申请号：US36799

申请日：1998-03-09

Applicant: Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Christopher M. Ryan ,  Eric Stanley Hall ,  Robin Sue Eichen Conn

Inventor： Patrick Richard Gruber ,  Jeffrey John Kolstad ,  Christopher M. Ryan ,  Eric Stanley Hall ,  Robin Sue Eichen Conn

IPC: C08K3/16 ,  A61L15/26 ,  A61L31/06 ,  C08G63/08 ,  C08G63/88 ,  C08G63/90 ,  C08J5/18 ,  C08K3/22 ,  C08K3/26 ,  C08K3/30 ,  C08K3/34 ,  C08K5/10 ,  C08K5/13 ,  C08K5/1515 ,  C08K5/1575 ,  C08K5/29 ,  C08K5/51 ,  C08K5/524 ,  C08K5/54 ,  C08L67/00 ,  C08L67/04 ,  C08L101/00 ,  C08L101/16 ,  C09D167/04 ,  D01F6/62 ,  D04H1/42 ,  D21H19/28 ,  D21H19/62

CPC classification number: C08J5/18 ,  A61L15/26 ,  A61L31/06 ,  C08G63/08 ,  C08G63/90 ,  C08L67/04 ,  C09D167/04 ,  D01F6/625 ,  D04H1/42 ,  D21H19/28 ,  D21H19/62 ,  C08G2230/00 ,  C08J2367/04 ,  C08L101/00

Abstract: A semi-crystalline film comprised of a lactide polymer. The lactide polymer comprises a plurality of poly(lactide) polymer chains, residual lactide in concentration of less than about 5 percent and water in concentration of less than about 2000 parts-per-million. A process for manufacturing a semi-crystalline film with the lactide polymer composition is also disclosed.

Abstract translation: 由丙交酯聚合物构成的半结晶膜。 丙交酯聚合物包含多个聚（丙交酯）聚合物链，浓度小于约5％的残余丙交酯和浓度小于约百万分之二千份的水。 还公开了用丙交酯聚合物组合物制造半结晶膜的方法。