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公开(公告)号：US20130236612A1
公开(公告)日：2013-09-12
申请号：US13822886
申请日：2011-09-13
CPC分类号： B65D81/34 , B32B1/02 , B32B27/08 , B32B27/304 , B32B27/34 , B32B27/36 , B32B2307/306 , B32B2307/31 , B32B2307/738 , B32B2439/70 , B65B1/02 , Y10T428/1334 , Y10T428/31736 , Y10T428/31739 , Y10T428/31786 , Y10T428/31797
摘要： A laminate includes the following substantially coextensive layers in the following order: (a) a non-sealable, self-supporting, thermoformable copolyester film layer having a first surface and a second surface, the second surface constituting an outermost, exposed surface of the laminate; (b) a laminating adhesive layer on the first surface of the thermoformable copolyester film layer; and (c) a self-supporting, thermoformable structural film layer having a first surface and a second surface, the first surface contacting the laminating adhesive layer. Polyethylene terephthalate constitutes at least 80% by weight of the self-supporting thermoformable copolyester film layer; the thermoformable structural film layer includes a polymer selected from the group consisting of polyamides, polypropylene, polyethylene, polyethylene terephthalate, ionomers, ethylene acrylic acid copolymers, ethylene vinyl acetate copolymers, polystyrene, ethylene vinyl alcohol copolymers and polyvinylidene chloride; the thermoformable copolyester film layer, the structural film layer and the laminate each shrink less than 5% in length and width upon exposure to boiling water for five seconds; and the laminate is thermoformable and its chloroform-soluble extractives meet the requirements of paragraph h(1) of 21 CFR §177.1630 as defined herein.
摘要翻译： 层压体按以下顺序包括以下基本上共同延伸的层：（a）具有第一表面和第二表面的不可密封的自支撑的可热成形的共聚酯膜层，所述第二表面构成层压体的最外面的暴露表面 ; （b）可热成型共聚酯膜层的第一表面上的层压粘合剂层; 和（c）具有第一表面和第二表面的自支撑的可热成形的结构膜层，所述第一表面接触层压粘合剂层。 聚对苯二甲酸乙二醇酯构成自支撑热成型共聚酯膜层的至少80重量％ 可热成形的结构膜层包括选自聚酰胺，聚丙烯，聚乙烯，聚对苯二甲酸乙二醇酯，离聚物，乙烯丙烯酸共聚物，乙烯乙酸乙烯酯共聚物，聚苯乙烯，乙烯乙烯醇共聚物和聚偏二氯乙烯的聚合物; 可热成型共聚酯膜层，结构膜层和层压体在暴露于沸水中5秒钟时的长度和宽度小于5％; 并且层压板是可热成型的，其氯仿可溶性提取物符合本文定义的21 CFR§177.1630段落h（1）的要求。
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公开(公告)号：US20100178318A9
公开(公告)日：2010-07-15
申请号：US11793045
申请日：2005-10-26
申请人： Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
发明人： Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
CPC分类号： A61K9/703 , A61K9/7084
摘要： A composite structure suitable for making transdermal delivery devices includes in sequence: (a) a liner film layer; (b) a containment layer having from zero to 15 wt. % content of vinyl acetate repeating units, the layer including either a thermal bonding copolyester resin or a combination of an ethylene-vinyl acetate component and a nonpolar polymer; and (c) a polyester film layer less than 20 μm in thickness. A drug layer lies either between the liner film layer and the containment layer or within a concave depression in the containment layer. A composition including an ethylene-vinyl acetate component and an ABA block copolymer, wherein the A segments of the block copolymer are styrenic segments, is also provided. The composition includes between 1 and 15 wt. % of vinyl acetate repeating units, based on the total weight of composition exclusive of any solvents.
摘要翻译： 适于制备透皮递送装置的复合结构包括：（a）衬垫膜层; （b）含有0至15wt。 乙酸乙烯酯重复单元的含量为％，该层包括热粘合共聚酯树脂或乙烯 - 乙酸乙烯酯组分和非极性聚合物的组合; 和（c）厚度小于20μm的聚酯薄膜层。 药物层位于衬垫膜层和容纳层之间或位于容纳层中的凹陷凹陷内。 还提供了包含乙烯 - 乙酸乙烯酯组分和ABA嵌段共聚物的组合物，其中嵌段共聚物的A链段是苯乙烯链段。 组合物包含1至15wt。 基于不包括任何溶剂的组合物的总重量的乙酸乙烯酯重复单元的百分比。
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3.发明授权公开(公告)号：US06255387B1
公开(公告)日：2001-07-03
申请号：US09004368
申请日：1998-01-08
IPC分类号： C08L2316
CPC分类号： C10M155/02 , C08F8/50 , C08F2800/10 , C08F2810/10 , C08L23/16 , C08L2203/40 , C08L2205/02 , C10M143/04 , C10M145/10 , C10M149/06 , C10M149/10 , C10M151/02 , C10M2205/00 , C10M2205/022 , C10M2205/024 , C10M2209/084 , C10M2209/086 , C10M2217/024 , C10M2217/028 , C10M2217/06 , C10M2221/041 , C10M2227/04 , C08F210/16 , C08L2666/04
摘要： A derivatized blend and a process for producing that blend in which a high ethylene content ethylene-propylene polymer and a lower ethylene content ethylene-propylene polymer are subjected to simultaneous blending and shearing to reduce their molecular weights and molecular weight distribution and then reacted with an organic compound to derivatize the blend. The sheared derivatized blend of polymers can function as a shear stable multifunctional viscosity index improver with improved low temperature properties and, in some cases, dispersancy antioxidant and anti-wear properties.
摘要翻译： 衍生化共混物和制备该共混物的方法，其中高乙烯含量的乙烯 - 丙烯聚合物和较低乙烯含量的乙烯 - 丙烯聚合物经受同时共混和剪切以降低其分子量和分子量分布，然后与 有机化合物衍生化共混物。 聚合物的剪切衍生化共混物可以用作具有改进的低温性能的剪切稳定的多功能粘度指数改进剂，并且在一些情况下可以具有分散的抗氧化和抗磨损性能。
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公开(公告)号：US20110052789A1
公开(公告)日：2011-03-03
申请号：US12890291
申请日：2010-09-24
申请人： Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
发明人： Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
IPC分类号： B05D3/00
CPC分类号： A61K9/703 , A61K9/7084
摘要： A composite structure suitable for making transdermal delivery devices includes in sequence: (a) a liner film layer; (b) a containment layer having from zero to 15 wt % content of vinyl acetate repeating units, the layer including either a thermal bonding copolyester resin or a combination of an ethylene-vinyl acetate component and a nonpolar polymer; and (c) a polyester film layer less than 20 μm in thickness. A drug layer lies either between the liner film layer and the containment layer or within a concave depression in the containment layer.A composition including an ethylene-vinyl acetate component and an ABA block copolymer, wherein the A segments of the block copolymer are styrenic segments, is also provided. The composition includes between 1 and 15 wt % of vinyl acetate repeating units, based on the total weight of composition exclusive of any solvents.
摘要翻译： 适于制备透皮递送装置的复合结构包括：（a）衬垫膜层; （b）包含乙酸乙烯酯重复单元含量为零至15重量％的容纳层，所述层包括热粘合共聚酯树脂或乙烯 - 乙酸乙烯酯组分与非极性聚合物的组合; 和（c）厚度小于20μm的聚酯薄膜层。 药物层位于衬垫膜层和容纳层之间或位于容纳层中的凹陷凹陷内。 还提供了包含乙烯 - 乙酸乙烯酯组分和ABA嵌段共聚物的组合物，其中嵌段共聚物的A链段是苯乙烯链段。 基于不包括任何溶剂的组合物的总重量，该组合物包含1至15重量％的乙酸乙烯酯重复单元。
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公开(公告)号：US5837773A
公开(公告)日：1998-11-17
申请号：US816213
申请日：1997-03-12
IPC分类号： C08F8/50 , C08L23/16 , C10M143/04 , C10M145/10 , C10M149/06 , C10M149/10 , C10M151/02 , C08L51/04 , C08L51/06
CPC分类号： C10M151/02 , B29C47/92 , C08F210/16 , C08F255/02 , C08F8/50 , C08L23/16 , C10M143/04 , C10M145/10 , C10M149/06 , C10M149/10 , B29C2947/92704 , B29C47/0004 , B29C47/38 , B29C47/805 , C08F2810/10 , C08L2203/40 , C08L2205/02 , C10M2205/00 , C10M2205/022 , C10M2205/024 , C10M2209/084 , C10M2209/086 , C10M2217/024 , C10M2217/028 , C10M2217/06 , C10M2221/041 , C10M2227/04
摘要： A blend and a process for producing that blend in which a high ethylene content ethylene-propylene polymer and a lower ethylene content ethylene-propylene polymer are subjected to simultaneous blending and shearing to reduce their molecular weights and molecular weight distribution. The sheared blend of polymers can function as a shear stable dispersant viscosity index improver with improved lower temperature properties or the hydrocarbon base for multifunctional for viscosity index improvers, motor fuel additives or polymeric dispersants.
摘要翻译： 共混物和制备该共混物的方法，其中高乙烯含量的乙烯 - 丙烯聚合物和较低乙烯含量的乙烯 - 丙烯聚合物经受同时共混和剪切以降低其分子量和分子量分布。 聚合物的剪切混合物可用作具有改进的较低温度性质的剪切稳定的分散剂粘度指数改进剂，或用于粘度指数改进剂，汽油燃料添加剂或聚合物分散剂的多功能烃基。
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公开(公告)号：US08840920B2
公开(公告)日：2014-09-23
申请号：US12890291
申请日：2010-09-24
申请人： Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
发明人： Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
CPC分类号： A61K9/703 , A61K9/7084
摘要： A composite structure suitable for making transdermal delivery devices includes in sequence: (a) a liner film layer; (b) a containment layer having from zero to 15 wt % content of vinyl acetate repeating units, the layer including either a thermal bonding copolyester resin or a combination of an ethylene-vinyl acetate component and a nonpolar polymer; and (c) a polyester film layer less than 20 μm in thickness. A drug layer lies either between the liner film layer and the containment layer or within a concave depression in the containment layer.A composition including an ethylene-vinyl acetate component and an ABA block copolymer, wherein the A segments of the block copolymer are styrenic segments, is also provided. The composition includes between 1 and 15 wt % of vinyl acetate repeating units, based on the total weight of composition exclusive of any solvents.
摘要翻译： 适于制备透皮递送装置的复合结构包括：（a）衬垫膜层; （b）包含乙酸乙烯酯重复单元含量为零至15重量％的容纳层，所述层包括热粘合共聚酯树脂或乙烯 - 乙酸乙烯酯组分与非极性聚合物的组合; 和（c）厚度小于20μm的聚酯薄膜层。 药物层位于衬垫膜层和容纳层之间或位于容纳层中的凹陷凹陷内。 还提供了包含乙烯 - 乙酸乙烯酯组分和ABA嵌段共聚物的组合物，其中嵌段共聚物的A链段是苯乙烯链段。 基于不包括任何溶剂的组合物的总重量，该组合物包含1至15重量％的乙酸乙烯酯重复单元。
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公开(公告)号：US20080211629A1
公开(公告)日：2008-09-04
申请号：US10592898
申请日：2005-03-16
申请人： Ken Evans , Stephen William Sankey , Dave Turner , Natalie Polack , Masahiko Kosuge , Peter N. Nugara
发明人： Ken Evans , Stephen William Sankey , Dave Turner , Natalie Polack , Masahiko Kosuge , Peter N. Nugara
CPC分类号： H04B5/0031 , G06K19/07749 , G06K19/07779 , G06K19/07783 , H05K1/0326 , Y10T156/10 , Y10T428/24843
摘要： A radio-frequency (RF) responsive tag comprising a heat-sealing substrate comprising a polyester layer, and an antenna comprising a patter of conductive material wherein said conductive material is in direct contact with a heat-sealing surface of the substrate, and wherein the shrinkage of the heat-sealing substrate is less than 5% at 190° C. over 30 minutes; a method of manufacture of said RF-response tag.
摘要翻译： 一种射频（RF）响应标签，其包括包含聚酯层的热封基板和包括导电材料的图案的天线，其中所述导电材料与基板的热封表面直接接触，并且其中 在190℃，30分钟内，热封基材的收缩率小于5％ 一种制造所述RF响应标签的方法。
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公开(公告)号：US20080131489A1
公开(公告)日：2008-06-05
申请号：US11793045
申请日：2005-10-26
申请人： Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
发明人： Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
CPC分类号： A61K9/703 , A61K9/7084
摘要： A composite structure suitable for making transdermal delivery devices includes in sequence: (a) a liner film layer; (b) a containment layer having from zero to 15 wt. % content of vinyl acetate repeating units, the layer including either a thermal bonding copolyester resin or a combination of an ethylene-vinyl acetate component and a nonpolar polymer; and (c) a polyester film layer less than 20 μm in thickness. A drug layer lies either between the liner film layer and the containment layer or within a concave depression in the containment layer. A composition including an ethylene-vinyl acetate component and an ABA block copolymer, wherein the A segments of the block copolymer are styrenic segments, is also provided. The composition includes between 1 and 15 wt. % of vinyl acetate repeating units, based on the total weight of composition exclusive of any solvents.
摘要翻译： 适于制备透皮递送装置的复合结构包括：（a）衬垫膜层; （b）含有0至15wt。 乙酸乙烯酯重复单元的含量为％，该层包括热粘合共聚酯树脂或乙烯 - 乙酸乙烯酯组分和非极性聚合物的组合; 和（c）厚度小于20μm的聚酯薄膜层。 药物层位于衬垫膜层和容纳层之间或位于容纳层中的凹陷凹陷内。 还提供了包含乙烯 - 乙酸乙烯酯组分和ABA嵌段共聚物的组合物，其中嵌段共聚物的A链段是苯乙烯链段。 组合物包含1至15wt。 基于不包括任何溶剂的组合物的总重量的乙酸乙烯酯重复单元的百分比。
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公开(公告)号：US5451636A
公开(公告)日：1995-09-19
申请号：US336420
申请日：1994-11-09
IPC分类号： C08F8/50 , C08L23/16 , C10M143/04 , C10M145/10 , C10M149/06 , C10M149/10 , C10M151/02 , C10M155/02 , C10N20/04 , C10N30/02 , C10N40/25 , C08L51/04 , C08L51/06
CPC分类号： C10M155/02 , B29C47/92 , C08F8/50 , C08L23/16 , C10M143/04 , C10M145/10 , C10M149/06 , C10M149/10 , C10M151/02 , B29C2947/92704 , B29C47/0004 , B29C47/38 , B29C47/805 , C08F2800/10 , C08F2810/10 , C08L2203/40 , C08L2205/02 , C10M2205/00 , C10M2205/022 , C10M2205/024 , C10M2209/084 , C10M2209/086 , C10M2217/024 , C10M2217/028 , C10M2217/06 , C10M2221/041 , C10M2227/04
摘要： A blend and a process for producing that blend in which a high ethylene content ethylene-propylene polymer and a lower ethylene content ethylene-propylene polymer are subjected to simultaneous blending and shearing to reduce their molecular weights and molecular weight distribution and to yield a product that can be recovered as a solid using conventional plastic processing equipment. The sheared blend of polymers can function as a shear stable viscosity index improver with improved lower temperature properties.
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公开(公告)号：US5451630A
公开(公告)日：1995-09-19
申请号：US337159
申请日：1994-11-09
IPC分类号： C10M143/02 , C10M143/04 , C10M143/14
CPC分类号： C10M143/02 , C10M2205/00 , C10M2205/02 , C10M2205/022 , C10M2205/024 , C10M2205/08
摘要： A blend and a process for producing that blend in which a high ethylene content ethylene-propylene polymer and a lower ethylene content ethylene-propylene polymer are subjected to simultaneous blending and shearing to reduce their molecular weights and molecular weight distribution and to yield a product that can be recovered as a solid using conventional plastic processing equipment. The sheared blend of polymers can function as a shear stable viscosity index improver with improved lower temperature properties.
摘要翻译： 共混物和制备该共混物的方法，其中高乙烯含量的乙烯 - 丙烯聚合物和较低乙烯含量的乙烯 - 丙烯聚合物经受同时共混和剪切以降低其分子量和分子量分布并产生产物 可以使用常规塑料加工设备作为固体回收。 聚合物的剪切混合物可用作具有改进的较低温度性质的剪切稳定粘度指数改进剂。
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