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    Mechanism to detect an unstable wavelength channel and limit its impact on a ROADM network
    5.
    发明授权
    Mechanism to detect an unstable wavelength channel and limit its impact on a ROADM network 有权
    检测不稳定波长通道并限制其对ROADM网络的影响的机制

    公开(公告)号：US08170417B2

    公开(公告)日：2012-05-01

    申请号：US12322734

    申请日：2009-02-06

    申请人： Qingyun Liu ,  Philip Wisseman

    发明人： Qingyun Liu ,  Philip Wisseman

    IPC分类号： H04J14/02 ,  H04B10/08

    CPC分类号： H04J14/0221 ,  H04J14/0204 ,  H04J14/0205 ,  H04J14/0212 ,  H04J14/0213

    摘要： A system and method for limiting the impact of an unstable wavelength on other wavelengths in a reconfigurable optical add/drop multiplexer (ROADM) network are disclosed. The method generally comprises measuring optical channel power at prescribed time intervals; for each measurement of channel power falling outside a predefined threshold, recording a threshold crossing event; comparing the recorded threshold crossing events to stored criteria indicative of an unstable wavelength channel; and removing an unstable wavelength from the ROADM network if the threshold crossing events exceed the stored criteria.

    摘要翻译： 公开了一种用于限制可重构光分插复用器（ROADM）网络中不稳定波长对其他波长的影响的系统和方法。 该方法通常包括以规定的时间间隔测量光信道功率; 对于每个测量的信道功率落在预定阈值之外，记录阈值交叉事件; 将记录的阈值交叉事件与指示不稳定波长信道的存储标准进行比较; 并且如果阈值跨越事件超过存储的标准，则从ROADM网络去除不稳定的波长。

    Human uncoupling protein 3
    7.
    发明授权
    Human uncoupling protein 3 失效
    人解偶联蛋白3

    公开(公告)号：US07001742B1

    公开(公告)日：2006-02-21

    申请号：US09081737

    申请日：1998-05-19

    申请人： Qingyun Liu ,  Fang Chen

    发明人： Qingyun Liu ,  Fang Chen

    IPC分类号： C12P21/06 ,  C07H17/00 ,  C07K14/00

    CPC分类号： C07K14/47

    摘要： An isolated nucleic acid molecule is disclosed which encodes a novel human uncoupling protein (UCP3), and related recombinant expression vectors, recombinant host cells and substantially purified forms of the UCP3 protein. The isolated nucleic acid and proteins disclosed herein will be useful in methods associated with identifying compounds which modulate energy expenditure and body weight regulation, as well as effecting diseases such as obesity and diabetes as well as mitochondria-associated hypermetabolism. Additionally, the isolated nucleic acids of the present ivention are candidates for gene therapy of a mammalian host, including humans.

    摘要翻译： 公开了分离的核酸分子，其编码新的人解偶联蛋白（UCP3）和相关的重组表达载体，重组宿主细胞和基本纯化的UCP3蛋白形式。 本文公开的分离的核酸和蛋白质可用于鉴定调节能量消耗和体重调节以及影响疾病如肥胖和糖尿病以及线粒体相关高代谢的化合物相关的方法。 另外，本发明的分离的核酸是包括人在内的哺乳动物宿主的基因治疗的候选物。

    Rat ob-receptors and nucleotides encoding them
    10.
    发明授权
    Rat ob-receptors and nucleotides encoding them 失效
    大鼠ob受体和编码它们的核苷酸

    公开(公告)号：US06281346B1

    公开(公告)日：2001-08-28

    申请号：US08803346

    申请日：1997-02-20

    申请人： John W. Hess ,  C. Thomas Caskey ,  Qingyun Liu ,  Michael Sean Phillips

    发明人： John W. Hess ,  C. Thomas Caskey ,  Qingyun Liu ,  Michael Sean Phillips

    IPC分类号： C12N1512

    CPC分类号： C07K14/72

    摘要： The rat ob receptor gene has been isolated and cloned. Two different alleles have been identified: the wild-type, and the fa-allele which differs from the wild type by only one base pair. The base pair change, however introduces an MspI restriction site into the DNA sequence, and also results in an amino acid change. Also part of the invention are the receptors, vectors containing the nucleic acid encoding the receptors, host cells transformed with this gene, and assays which use the gene or protein and identify new ligands.

    摘要翻译： 已经分离和克隆了大鼠ob受体基因。 已经鉴定了两种不同的等位基因：野生型和fa型等位基因仅与一个碱基对不同于野生型。 碱基对改变然后将MspI限制性位点引入DNA序列，并导致氨基酸变化。 本发明的一部分还包括受体，含有编码受体的核酸的载体，用该基因转化的宿主细胞，以及使用该基因或蛋白质并鉴定新配体的测定法。