Rapid Melt Controlled Release Taste-Masked Compositions
    1.
    发明申请
    Rapid Melt Controlled Release Taste-Masked Compositions 审中-公开
    快速熔融控制释放味道掩蔽的组合物

    公开(公告)号:US20130071476A1

    公开(公告)日:2013-03-21

    申请号:US13589101

    申请日:2012-08-31

    摘要: Rapid melt tablets that dissolve and release an active component in the oral cavity are comprised of a pharmaceutical active ingredient such as dextromethorphan complexed with a resin that is effective in taste-masking the otherwise bitter taste of the active making it convenient for oral administration. The drug/resin-complexed particles can be coated with water swellable or water insoluble polymers to impart controlled release properties to the active ingredient. A rapid melt tablet also comprises diluents, sweeteners, flavors, disintegrants and other excipients to form granules that can be compressed into tablets at low pressure without the need for a binding agent.

    摘要翻译: 在口腔中溶解和释放活性组分的快速熔融片剂包括药物活性成分,例如与树脂复合的右美沙芬,其有效地掩盖了活性物质的其它苦味,使其便于口服给药。 药物/树脂复合颗粒可以涂覆水溶胀性或水不溶性聚合物,以赋予活性成分控释性。 快速熔融片剂还包含稀释剂,甜味剂,调味剂,崩解剂和其它赋形剂,以形成可以在低压下压制成片剂而不需要结合剂的颗粒剂。

    Rapid-Melt Compositions and Methods of Making Same
    4.
    发明申请
    Rapid-Melt Compositions and Methods of Making Same 审中-公开
    快速熔体组合物及其制备方法

    公开(公告)号:US20100010101A1

    公开(公告)日:2010-01-14

    申请号:US12501652

    申请日:2009-07-13

    申请人: S. Rao Cherukuri

    发明人: S. Rao Cherukuri

    IPC分类号: A61K47/04 A61K47/12

    摘要: The present invention provides a novel rapid-melt pharmaceutical composition comprising a binder, a super emulsifier, a diluent/bulking material; and an active ingredient. The present invention also provides a rapid-melt bead composition comprising a binder having a melting point from about 20 to about 90° C., an emulsifier; a diluent/bulking material; and an active ingredient. Further, the present invention provides a chew tablet composition comprising a binder; an emulsifier having a melting point of greater than about 40° C.; a diluent/bulking material; and an active ingredient. Methods of making the disclosed compositions are also described.

    摘要翻译: 本发明提供一种新型的快速熔融药物组合物,其包含粘合剂,超级乳化剂,稀释剂/填充材料; 和活性成分。 本发明还提供一种包含熔点约20-90℃的粘合剂的快速熔融珠组合物,一种乳化剂; 稀释剂/膨胀材料; 和活性成分。 此外,本发明提供一种包含粘合剂的咀嚼片组合物; 具有大于约40℃的熔点的乳化剂; 稀释剂/膨胀材料; 和活性成分。 还描述了制备所公开的组合物的方法。

    Rapidly disintegrating solid oral dosage form of liquid dispersions
    6.
    发明申请
    Rapidly disintegrating solid oral dosage form of liquid dispersions 审中-公开
    快速分散固体口服剂型的液体分散体

    公开(公告)号:US20070243248A1

    公开(公告)日:2007-10-18

    申请号:US11787115

    申请日:2007-04-12

    申请人: S. Rao Cherukuri

    发明人: S. Rao Cherukuri

    IPC分类号: A61K9/20

    摘要: Solid dose rapidly disintegrating compositions for administering pharmaceutical and nutritional supplement agents and methods for the preparation thereof are disclosed and described. Preparation methods which maintain the particulate size of an active agent at the pre-processing size in the final composition are further disclosed. The ability to maintain such particulate size provides a number of advantages, including improved bioavailability and more accurate dosing.

    摘要翻译: 公开和描述了用于施用药物和营养补充剂的固体剂量快速崩解组合物及其制备方法。 进一步公开了将最终组合物中预处理尺寸的活性剂的颗粒尺寸保持的制备方法。 保持这种颗粒尺寸的能力提供了许多优点,包括改进的生物利用度和更精确的给药。

    Rapid-melt semi-solid compositions, methods of making same and method of using same
    7.
    发明授权
    Rapid-melt semi-solid compositions, methods of making same and method of using same 失效
    快速熔融半固体组合物,制备方法和使用方法

    公开(公告)号:US06375982B1

    公开(公告)日:2002-04-23

    申请号:US09610489

    申请日:2000-07-05

    IPC分类号: A61K914

    CPC分类号: A61K9/0056

    摘要: A novel rapid-melt, semi-solid molded composition including at least one binder in an amount from about 0.01% to about 70% by weight; a salivating agent in an amount from about 0.05% to about 15% by weight, a diluent/bulking material in an amount from about 10% to about 90% by weight; and an active material in an amount from about 0.001% to about 70% by weight. Further, the inventive subject matter includes a method of preparing a rapid-melt, semi-solid molded composition comprising the steps of: melting at least one binder in an amount from about 0.01% to about 70% by weight with a salivating agent in an amount from about 0.05% to about 15% by weight, to form a mixture; mixing an active material with said mixture to form an active mixture; mixing a diluent/bulking material with said active mixture to form a final mixture; and molding said final mixture into said semi-solid molded composition.

    摘要翻译: 一种新型的快速熔融的半固体模塑组合物,其包含至少一种量为约0.01%至约70%重量的粘合剂; 约0.05重量%至约15重量%的唾液酸化剂,约10重量%至约90重量%的稀释剂/膨胀材料; 和约0.001重量%至约70重量%的量的活性物质。 此外,本发明的主题包括制备快速熔融的半固体模塑组合物的方法,其包括以下步骤:将熔化至少一种粘合剂的量为约0.01重量%至约70重量% 约0.05重量%至约15重量%,以形成混合物; 将活性物质与所述混合物混合以形成活性混合物; 将稀释剂/膨胀材料与所述活性混合物混合以形成最终混合物; 并将所述最终混合物模塑成所述半固体模塑组合物。

    Method and system of application delivery through application template to client device
    8.
    发明授权
    Method and system of application delivery through application template to client device 失效
    通过应用程序模板将应用程序传递到客户端设备的方法和系统

    公开(公告)号:US08543641B2

    公开(公告)日:2013-09-24

    申请号:US12826696

    申请日:2010-06-30

    IPC分类号: G06F15/16

    CPC分类号: G06Q10/10 G06F8/60 G06F9/455

    摘要: In one embodiment, a method of a client device includes accessing an application through an application template. The application template resides on server device. The method also includes accessing application based on a response to request of a user interface. In addition, the method includes processing the application through a processor such that the application accesses the application template such that the client device permits an access of the application through the application template. The method further includes executing the application through the application template such that an execution of the application through the application template emulates the execution of the application installed on an operating system of the client device. The method also includes executing a function of the application template based on a demand of a user through the response to the request of the user such that the file is accessed when required by the application.

    摘要翻译: 在一个实施例中,客户端设备的方法包括通过应用模板访问应用。 应用模板驻留在服务器设备上。 该方法还包括基于对用户界面的请求的响应来访问应用。 此外,该方法包括通过处理器处理应用程序,使得应用程序访问应用程序模板,使得客户端设备允许通过应用程序模板访问应用程序。 该方法还包括通过应用模板来执行应用程序,使得通过应用模板的应用程序的执行模拟安装在客户端设备的操作系统上的应用的执行。 该方法还包括通过对用户的请求的响应,基于用户的需求来执行应用模板的功能,使得在应用需要时访问该文件。

    Method and system of operating system independence
    9.
    发明授权
    Method and system of operating system independence 失效
    操作系统独立性的方法和系统

    公开(公告)号:US08346854B2

    公开(公告)日:2013-01-01

    申请号:US12826719

    申请日:2010-06-30

    IPC分类号: G06F15/16

    CPC分类号: G06F8/76 G06F9/541

    摘要: A method and system of operating system independent cloud computing is provided. In one embodiment, a method of a client device includes accessing a first application through a first application template. The first application template resides on a server. The method also includes accessing the first application based on a response to a request of a user interface of the client device. Furthermore, the method includes processing the first application through a processor such that the first application accesses the first application template such that the client device permits an access of the first application through the first application template. The method also includes executing the first application through the first application template such that an execution of the first application through the first application template emulates the execution of the first application installed on an operating system of the client device.

    摘要翻译: 提供了一种操作系统独立云计算的方法和系统。 在一个实施例中,客户端设备的方法包括通过第一应用模板访问第一应用。 第一个应用程序模板驻留在服务器上。 该方法还包括基于对客户端设备的用户界面的请求的响应来访问第一应用。 此外,该方法包括通过处理器处理第一应用,使得第一应用访问第一应用模板,使得客户端设备允许通过第一应用模板访问第一应用。 该方法还包括通过第一应用模板执行第一应用程序,使得通过第一应用模板执行第一应用程序模拟安装在客户端设备的操作系统上的第一应用的执行。