Location and effect of adsorbed chemicals on the dielectric substructure
of membranes by ultra low frequency spectrometry
    2.
    发明授权
    Location and effect of adsorbed chemicals on the dielectric substructure of membranes by ultra low frequency spectrometry 失效
    通过超低频光谱法吸附化学物质对膜介电子结构的位置和作用

    公开(公告)号:US4214203A

    公开(公告)日:1980-07-22

    申请号:US916147

    申请日:1978-06-16

    摘要: Apparatus and method whereby ultra low frequency dielectric measurements allow a determination to be made of the parameters (dielectric constant, thickness and conductivity) characterizing electrically distinct layers with membranes such as bimolecular lipid or protein membranes (i.e. the major components of the membranes of living cells).The location and effect of chemicals such as anaesthetics, tranquilizers, hormones and other substances of pharmacological and general biological interest which are adsorbed into these or other membranes can be determined. The effects of these chemicals can be quantitatively specified in terms of this effect of the substructural dielectric parameters.

    摘要翻译: 超低频电介质测量的装置和方法允许通过诸如双分子脂质或蛋白质膜(即活细胞膜的主要组分)来表征电分离层的参数(介电常数,厚度和电导率) )。 可以确定吸附在这些或其他膜中的药物如麻醉剂,镇定剂,激素和其他药物和一般生物学兴趣的物质的位置和作用。 这些化学物质的影响可以根据这种低结构介电参数的影响进行定量的定义。