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    Shear-Enhanced Systems And Methods For Removing Waste Materials And Liquid From The Blood
    2.
    发明申请
    Shear-Enhanced Systems And Methods For Removing Waste Materials And Liquid From The Blood 审中-公开
    剪切增强系统和从血液中去除废物和液体的方法

    公开(公告)号：US20060278581A1

    公开(公告)日：2006-12-14

    申请号：US11465952

    申请日：2006-08-21

    Applicant: Julie Moriarty ,  Rohit Vishnoi ,  Gretchen Kunas

    Inventor： Julie Moriarty ,  Rohit Vishnoi ,  Gretchen Kunas

    IPC: B01D61/00

    CPC classification number: B01D63/16 ,  A61M1/16 ,  A61M1/262 ,  A61M1/265 ,  A61M1/3417 ,  A61M1/342 ,  A61M1/3437 ,  A61M1/3458 ,  B01D61/145 ,  B01D61/18 ,  B01D61/28 ,  B01D63/06 ,  B01D65/08 ,  B01D2321/2033 ,  B01D2321/2041 ,  B01D2321/205

    Abstract: Systems and methods convey the blood through a gap defined between an inner surface that is located about an axis and an outer surface that is concentric with the inner surface. At least one of the inner and outer surfaces carries a membrane that consists essentially of either a hemofiltration membrane or a hemodialysis membrane. The systems and methods cause relative movement between the inner and outer surfaces about the axis at a selected surface velocity, taking into account the size of the gap. The relative movement of the two surfaces creates movement of the blood within the gap, which creates vortical flow conditions that induce transport of cellular blood components from the membrane while plasma water and waste material are transported to the membrane for transport across the membrane. Shear-enhanced transport of waste materials and blood plasma water results.

    Abstract translation: 系统和方法通过限定在围绕轴线的内表面和与内表面同心的外表面之间的间隙传送血液。 内表面和外表面中的至少一个带有基本上由血液滤过膜或血液透析膜组成的膜。 系统和方法考虑到间隙的大小，引起内表面和外表面之间围绕轴线以所选表面速度的相对运动。 两个表面的相对运动产生血液在间隙内的移动，这产生了涡旋流动条件，其诱导细胞血液成分从膜的运输，而等离子体水和废物被输送到膜以便跨过膜运输。 剪切加强了废料和血浆水的运输。

    Shear-Enhanced Systems and Methods for Removing Waste Materials and Liquid from the Blood
    6.
    发明申请
    Shear-Enhanced Systems and Methods for Removing Waste Materials and Liquid from the Blood 有权
    用于从血液中去除废物和液体的剪切增强系统和方法

    公开(公告)号：US20070181500A1

    公开(公告)日：2007-08-09

    申请号：US11734579

    申请日：2007-04-12

    Applicant: Julie Moriarty ,  Rohit Vishnoi ,  Gretchen Kunas

    Inventor： Julie Moriarty ,  Rohit Vishnoi ,  Gretchen Kunas

    IPC: B01D61/00

    CPC classification number: B01D63/16 ,  A61M1/16 ,  A61M1/262 ,  A61M1/265 ,  A61M1/3417 ,  A61M1/342 ,  A61M1/3437 ,  A61M1/3458 ,  B01D61/145 ,  B01D61/18 ,  B01D61/28 ,  B01D63/06 ,  B01D65/08 ,  B01D2321/2033 ,  B01D2321/2041 ,  B01D2321/205

    Abstract: Systems and methods convey the blood through a gap defined between an inner surface that is located about an axis and an outer surface that is concentric with the inner surface. At least one of the inner and outer surfaces carries a membrane that consists essentially of either a hemofiltration membrane or a hemodialysis membrane. The systems and methods cause relative movement between the inner and outer surfaces about the axis at a selected surface velocity, taking into account the size of the gap. The relative movement of the two surfaces creates movement of the blood within the gap, which creates vortical flow conditions that induce transport of cellular blood components from the membrane while plasma water and waste material are transported to the membrane for transport across the membrane. Shear-enhanced transport of waste materials and blood plasma water results.

    Abstract translation: 系统和方法通过限定在围绕轴线的内表面和与内表面同心的外表面之间的间隙传送血液。 内表面和外表面中的至少一个带有基本上由血液滤过膜或血液透析膜组成的膜。 系统和方法考虑到间隙的大小，引起内表面和外表面之间围绕轴线以所选表面速度的相对运动。 两个表面的相对运动产生血液在间隙内的移动，这产生了涡旋流动条件，其诱导细胞血液成分从膜的运输，而等离子体水和废物被输送到膜以便跨过膜运输。 剪切加强了废料和血浆水的运输。

    Fluid pressure actuated blood pumping systems and methods with continuous inflow and pulsatile outflow conditions
    7.
    发明授权
    Fluid pressure actuated blood pumping systems and methods with continuous inflow and pulsatile outflow conditions 有权
    流体压力启动的血液泵送系统和具有连续流入和脉动流出条件的方法

    公开(公告)号：US06723062B1

    公开(公告)日：2004-04-20

    申请号：US09390265

    申请日：1999-09-03

    Applicant: Tom Westberg ,  Rohit Vishnoi ,  Mark R Vandlik

    Inventor： Tom Westberg ,  Rohit Vishnoi ,  Mark R Vandlik

    IPC: A61M3700

    CPC classification number: A61M1/3696 ,  A61M1/1006 ,  A61M1/1037 ,  A61M1/1062 ,  A61M1/1086 ,  A61M1/1087 ,  A61M1/1096 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3633 ,  A61M2205/128 ,  A61M2205/331 ,  A61M2205/3334 ,  A61M2205/3393 ,  F04B13/02 ,  F04B43/026 ,  F04B49/065 ,  F04B2205/09

    Abstract: Blood processing systems and related methods place first and second fluid pressure actuated pump stations in in-line communication between a source and a destination. The systems and methods apply fluid pressure pump strokes to the first and second pump stations to convey fluid from the source to the destination. The systems and methods switch between a first flow mode and a second flow mode. In the first flow mode, the pump strokes draw a fluid volume into the first pump station from the source and expel a fluid volume from the second pump station to the destination. In the second flow mode, the pump strokes draw a fluid volume into the second pump station from the source and expel a fluid volume from the first pump station to the destination. The systems and methods synchronize the pump strokes so that fluid flow from the source is essentially continuous while fluid flow to the destination is pulsatile.

    Abstract translation: 血液处理系统和相关方法使第一和第二流体压力致动泵站在源和目的地之间处于在线通信。 系统和方法将流体压力泵冲程施加到第一和第二泵站以将流体从源传送到目的地。 系统和方法在第一流模式和第二流模式之间切换。 在第一流动模式中，泵冲程从源将流体体积从第二泵站排出到第一泵站中，并将流体体积从第二泵站排出到目的地。 在第二流动模式中，泵冲程从源将流体体积从第二泵站抽出到第二泵站，并将流体体积从第一泵站排出到目的地。 系统和方法使泵冲程同步，使得来自源的流体流动基本上是连续的，而流到目的地的流体是脉动的。

    Dialyzer clearance check system
    9.
    发明授权
    Dialyzer clearance check system 失效
    透析器检查系统

    公开(公告)号：US5110477A

    公开(公告)日：1992-05-05

    申请号：US479504

    申请日：1990-02-13

    Applicant: David B. Howard ,  Rodney Kenley ,  Dennis Berry ,  Prakash Keshaviah ,  Rohit Vishnoi

    Inventor： David B. Howard ,  Rodney Kenley ,  Dennis Berry ,  Prakash Keshaviah ,  Rohit Vishnoi

    IPC: A61M1/16 ,  B01D61/32 ,  B01D65/10

    CPC classification number: A61M1/16 ,  A61M1/1609 ,  A61M1/1613 ,  B01D61/32 ,  B01D65/10

    Abstract: A method for determining the clearance competency of dialyzers utilized in renal hemodialysis comprises measuring the conductivity of a dialysate solution of low initial conductivity while circulating a priming solution of greater conductivity on the blood side of the dialyzer, correlating the rate of dialysis of molecules contained in the printing solution to known clearance rates for urea or other targeted blood impurity for the types and compositions of the particular dialysis membranes being utilized, and calculating the precise length of treatment time or other treatment parameters required to cleanse the blood to be dialyzed of impurities and biotoxins to a predicted target value. Failsafe control means which prevents mistakes in connecting unsafe fluid sources to the dialyzer is also provided.

    Abstract translation: 用于确定在肾血液透析中使用的透析器的清除能力的方法包括测量低初始电导率的透析液的电导率，同时在透析器的血液侧循环更大导电性的引发溶液，将包含在其中的分子的透析速率相关联 使用针对特定透析膜的类型和组成的尿素或其他靶向血液杂质的已知清除率的印刷溶液，并计算清洁待透析的血液中杂质所需的治疗时间或其他治疗参数的精确长度， 生物毒素达到预期目标值。 还提供了防止将不安全流体源连接到透析器的错误的故障安全控制装置。

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