公开(公告)号：US20060178611A9

公开(公告)日：2006-08-10

申请号：US10828359

申请日：2004-04-20

申请人： Tom Westberg ,  Rohit Vishnoi ,  Mark Vandlik

发明人： Tom Westberg ,  Rohit Vishnoi ,  Mark Vandlik

IPC分类号： A61M37/00

CPC分类号： A61M1/3696 ,  A61M1/1006 ,  A61M1/1037 ,  A61M1/1062 ,  A61M1/1086 ,  A61M1/1087 ,  A61M1/1096 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3633 ,  A61M2205/128 ,  A61M2205/331 ,  A61M2205/3334 ,  A61M2205/3393 ,  F04B13/02 ,  F04B43/026 ,  F04B49/065 ,  F04B2205/09

摘要： Blood processing systems and related methods place first and second fluid pressure actuated pump stations in in-line communication between a source and a destination. The systems and methods apply fluid pressure pump strokes to the first and second pump stations to convey fluid from the source to the destination. The systems and methods switch between a first flow mode and a second flow mode. In the first flow mode, the pump strokes draw a fluid volume into the first pump station from the source and expel a fluid volume from the second pump station to the destination. In the second flow mode, the pump strokes draw a fluid volume into the second pump station from the source and expel a fluid volume from the first pump station to the destination. The systems and methods synchronize the pump strokes so that fluid flow from the source is essentially continuous while fluid flow to the destination is pulsatile.

摘要翻译： 血液处理系统和相关方法使第一和第二流体压力致动泵站在源和目的地之间处于在线通信。 系统和方法将流体压力泵冲程施加到第一和第二泵站以将流体从源传送到目的地。 系统和方法在第一流模式和第二流模式之间切换。 在第一流动模式中，泵冲程从源将流体体积从第二泵站排出到第一泵站中，并将流体体积从第二泵站排出到目的地。 在第二流动模式中，泵冲程从源将流体体积从第二泵站抽出到第二泵站，并将流体体积从第一泵站排出到目的地。 系统和方法使泵冲程同步，使得来自源的流体流动基本上是连续的，而流到目的地的流体是脉动的。

公开(公告)号：US20060161092A1

公开(公告)日：2006-07-20

申请号：US11375965

申请日：2006-03-15

申请人： Tom Westberg ,  Rohit Vishnoi ,  Mark Vandlik

发明人： Tom Westberg ,  Rohit Vishnoi ,  Mark Vandlik

IPC分类号： A61M37/00

CPC分类号： A61M1/3693 ,  A61M1/0218 ,  A61M1/1006 ,  A61M1/1037 ,  A61M1/1062 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3633 ,  A61M1/3636 ,  A61M1/3696 ,  A61M2205/128 ,  A61M2205/331 ,  A61M2205/3393

摘要： A multiple function pump station performs different on-line processing tasks. The pump station can be operated in one mode to draw blood from a donor and, in another mode, be operated to return blood to the donor. The pump station used to draw blood from a donor can also be used to perform subsequent blood processing tasks, such as mixing or processing additive fluids with the blood, or transfering a harvested blood component to a storage container, or finishing the processing of a harvested blood component.

摘要翻译： 多功能泵站执行不同的在线处理任务。 泵站可以以一种模式操作以从供体抽取血液，并且在另一种模式中操作以将血液返回给供体。 用于从供体抽取血液的泵站也可用于执行随后的血液处理任务，例如将添加剂与血液混合或加工，或将收集的血液成分转移到储存容器中，或完成收获的加工 血液成分。

公开(公告)号：US20050234384A1

公开(公告)日：2005-10-20

申请号：US10828359

申请日：2004-04-17

申请人： Tom Westberg ,  Rohit Vishnoi ,  Mark Vandlik

发明人： Tom Westberg ,  Rohit Vishnoi ,  Mark Vandlik

IPC分类号： A61M1/02 ,  A61M1/10 ,  A61M1/30 ,  A61M1/36 ,  A61M37/00 ,  F04B13/02 ,  F04B43/02 ,  F04B49/06

CPC分类号： A61M1/3696 ,  A61M1/1006 ,  A61M1/1037 ,  A61M1/1062 ,  A61M1/1086 ,  A61M1/1087 ,  A61M1/1096 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3633 ,  A61M2205/128 ,  A61M2205/331 ,  A61M2205/3334 ,  A61M2205/3393 ,  F04B13/02 ,  F04B43/026 ,  F04B49/065 ,  F04B2205/09

摘要： Blood processing systems and related methods place first and second fluid pressure actuated pump stations in in-line communication between a source and a destination. The systems and methods apply fluid pressure pump strokes to the first and second pump stations to convey fluid from the source to the destination. The systems and methods switch between a first flow mode and a second flow mode. In the first flow mode, the pump strokes draw a fluid volume into the first pump station from the source and expel a fluid volume from the second pump station to the destination. In the second flow mode, the pump strokes draw a fluid volume into the second pump station from the source and expel a fluid volume from the first pump station to the destination. The systems and methods synchronize the pump strokes so that fluid flow from the source is essentially continuous while fluid flow to the destination is pulsatile.

摘要翻译： 血液处理系统和相关方法使第一和第二流体压力致动泵站在源和目的地之间处于在线通信。 系统和方法将流体压力泵冲程施加到第一和第二泵站以将流体从源传送到目的地。 系统和方法在第一流模式和第二流模式之间切换。 在第一流动模式中，泵冲程从源将流体体积从第二泵站排出到第一泵站中，并将流体体积从第二泵站排出到目的地。 在第二流动模式中，泵冲程从源将流体体积从第二泵站抽出到第二泵站，并将流体体积从第一泵站排出到目的地。 系统和方法使泵冲程同步，使得来自源的流体流动基本上是连续的，而流到目的地的流体是脉动的。

公开(公告)号：US20060178612A9

公开(公告)日：2006-08-10

申请号：US10828440

申请日：2004-04-20

申请人： Mark Vandlik ,  Tom Westberg

发明人： Mark Vandlik ,  Tom Westberg

IPC分类号： A61M37/00

CPC分类号： A61M1/3696 ,  A61M1/0218 ,  A61M1/1006 ,  A61M1/1037 ,  A61M1/1062 ,  A61M1/1086 ,  A61M1/1087 ,  A61M1/1096 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3633 ,  A61M2205/128 ,  A61M2205/331 ,  A61M2205/3334 ,  A61M2205/3393 ,  F04B13/02 ,  F04B43/026 ,  F04B49/065 ,  F04B2205/09

摘要： A blood processing system comprises a processing chamber to process blood and a fluid flow cassette that communicates with the processing chamber. The cassette comprises a body, a pump chamber formed in the body, and a flexible diaphragm on the pump chamber responsive to an applied fluid pressures for flexure toward and away from the pump chamber to pump fluid through the pump chamber. The cassette also includes a flow path formed, at least in part, in the body to couple the pump chamber in fluid flow communication with the processing chamber, to convey fluid pumped by the pump chamber into the processing chamber. The cassette also includes an in line cavity formed in the body and located in the flow path to trap air to prevent entry of air into the processing chamber.

公开(公告)号：US20050234385A1

公开(公告)日：2005-10-20

申请号：US10828440

申请日：2004-04-17

申请人： Mark Vandlik ,  Tom Westberg

发明人： Mark Vandlik ,  Tom Westberg

IPC分类号： A61M1/10 ,  A61M1/30 ,  A61M1/36 ,  A61M37/00 ,  F04B13/02 ,  F04B43/02 ,  F04B49/06

CPC分类号： A61M1/3696 ,  A61M1/0218 ,  A61M1/1006 ,  A61M1/1037 ,  A61M1/1062 ,  A61M1/1086 ,  A61M1/1087 ,  A61M1/1096 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3633 ,  A61M2205/128 ,  A61M2205/331 ,  A61M2205/3334 ,  A61M2205/3393 ,  F04B13/02 ,  F04B43/026 ,  F04B49/065 ,  F04B2205/09

摘要： A blood processing system comprises a processing chamber to process blood and a fluid flow cassette that communicates with the processing chamber. The cassette comprises a body, a pump chamber formed in the body, and a flexible diaphragm on the pump chamber responsive to an applied fluid pressures for flexure toward and away from the pump chamber to pump fluid through the pump chamber. The cassette also includes a flow path formed, at least in part, in the body to couple the pump chamber in fluid flow communication with the processing chamber, to convey fluid pumped by the pump chamber into the processing chamber. The cassette also includes an in line cavity formed in the body and located in the flow path to trap air to prevent entry of air into the processing chamber.

摘要翻译： 血液处理系统包括处理血液的处理室和与处理室连通的流体流动盒。 盒体包括主体，形成在主体中的泵室，以及响应于所施加的流体压力的柔性膜片，其响应于朝向和远离泵室的挠曲，以将流体泵送通过泵室。 该盒还包括至少部分地形成在主体中的流路，以将泵室与处理室流体流动连通，以将泵室泵送的流体输送到处理室中。 该盒还包括形成在主体中并且位于流动路径中的吸入空气以防止空气进入处理室的入口腔。

公开(公告)号：US10188534B2

公开(公告)日：2019-01-29

申请号：US11939627

申请日：2007-11-14

申请人： Doug Molland ,  Jianlu Ma ,  Joe Tatalovich ,  Jeff Vogel ,  Josh Dudney ,  Mark Vandlik ,  Richard Kusleika

发明人： Doug Molland ,  Jianlu Ma ,  Joe Tatalovich ,  Jeff Vogel ,  Josh Dudney ,  Mark Vandlik ,  Richard Kusleika

IPC分类号： A61F2/90 ,  A61F2/91

摘要： A stent for reducing the passage of emboli into body lumen once deployed includes a structural portion and a barrier portion. The structural portion, when expanded in a conduit, provides sufficient strength to maintain an open lumen in the conduit. The barrier portion reduces migration of emboli from the wall of the conduit through the structural portion and into the lumen. Stent delivery systems capable of delivering and deploying the stent are disclosed.

公开(公告)号：US07357897B2

公开(公告)日：2008-04-15

申请号：US11032271

申请日：2005-01-10

申请人： Kelly B Smith ,  Mark Vandlik ,  Michael Kast

发明人： Kelly B Smith ,  Mark Vandlik ,  Michael Kast

IPC分类号： A61M1/00 ,  A61M35/00 ,  B01D33/15 ,  B01D21/26 ,  B04B5/10

CPC分类号： A61M1/1037 ,  A61M1/0209 ,  A61M1/0218 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3633 ,  A61M1/3636 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2205/12 ,  A61M2205/128 ,  A61M2205/331 ,  A61M2205/3393

摘要： Blood processing systems and methods convey blood cells from a blood cell source into a blood component collection flow channel that includes a blood cell storage container and an in-line filter to remove leukocytes from blood cells before entering the blood cell storage container. The systems and methods also convey additive solution from an additive solution source into the blood component collection flow channel. The systems and methods alternate the conveyance of blood cells through the filter with the conveyance of additive solution through the filter.

摘要翻译： 血液处理系统和方法将血液细胞从血细胞源传送到血液成分收集流通道中，该血液成分收集流通道包括血细胞储存容器和在线过滤器，以在进入血细胞储存容器之前从血液细胞中除去白细胞。 所述系统和方法还将添加剂溶液从添加剂溶液源输送到血液成分收集流动通道中。 系统和方法通过过滤器输送添加剂溶液来交替通过过滤器的血细胞的输送。

公开(公告)号：US20080167708A1

公开(公告)日：2008-07-10

申请号：US11939627

申请日：2007-11-14

申请人： Doug Molland ,  Jianlu Ma ,  Joe Tatalovich ,  Jeff Vogel ,  Josh Dudney ,  Mark Vandlik ,  Richard Kusleika

发明人： Doug Molland ,  Jianlu Ma ,  Joe Tatalovich ,  Jeff Vogel ,  Josh Dudney ,  Mark Vandlik ,  Richard Kusleika

IPC分类号： A61F2/06

CPC分类号： A61F2/90 ,  A61F2/91 ,  A61F2210/0057 ,  A61F2210/0076 ,  A61F2220/0041 ,  A61F2250/0023 ,  A61F2250/0048

摘要： A stent for reducing the passage of emboli into body lumen once deployed includes a structural portion and a barrier portion. The structural portion, when expanded in a conduit, provides sufficient strength to maintain an open lumen in the conduit. The barrier portion reduces migration of emboli from the wall of the conduit through the structural portion and into the lumen. Stent delivery systems capable of delivering and deploying the stent are disclosed.

摘要翻译： 一旦展开，用于减少栓塞进入体腔的通道的支架包括结构部分和阻挡部分。 结构部分当在导管中膨胀时提供足够的强度以维持管道中的开口腔。 阻挡部分减少栓子从导管壁穿过结构部分进入内腔的移动。 公开了能够递送和展开支架的支架输送系统。

公开(公告)号：US20050124927A1

公开(公告)日：2005-06-09

申请号：US11032271

申请日：2005-01-10

申请人： Kelly Smith ,  Mark Vandlik ,  Michael Kast

发明人： Kelly Smith ,  Mark Vandlik ,  Michael Kast

IPC分类号： A61M1/02 ,  A61K35/14 ,  A61K35/18 ,  A61M1/10 ,  A61M1/30 ,  A61M1/34 ,  A61M1/36 ,  A61P7/00 ,  A61M37/00 ,  B01D37/00

CPC分类号： A61M1/1037 ,  A61M1/0209 ,  A61M1/0218 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3633 ,  A61M1/3636 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2205/12 ,  A61M2205/128 ,  A61M2205/331 ,  A61M2205/3393

摘要： Blood processing systems and methods convey blood cells from a blood cell source into a blood component collection flow channel that includes a blood cell storage container and an in-line filter to remove leukocytes from blood cells before entering the blood cell storage container. The systems and methods also convey additive solution from an additive solution source into the blood component collection flow channel. The systems and methods alternate the conveyance of blood cells through the filter with the conveyance of additive solution through the filter.

公开(公告)号：US06875191B2

公开(公告)日：2005-04-05

申请号：US09976832

申请日：2001-10-13

申请人： Kelly B Smith ,  Mark Vandlik ,  Michael Kast

发明人： Kelly B Smith ,  Mark Vandlik ,  Michael Kast

IPC分类号： A61M1/02 ,  A61K35/14 ,  A61K35/18 ,  A61M1/10 ,  A61M1/30 ,  A61M1/34 ,  A61M1/36 ,  A61P7/00 ,  A61M37/00 ,  B01D45/00 ,  B04B7/18 ,  C02F1/38

CPC分类号： A61M1/1037 ,  A61M1/0209 ,  A61M1/0218 ,  A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3633 ,  A61M1/3636 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2205/12 ,  A61M2205/128 ,  A61M2205/331 ,  A61M2205/3393

摘要： Blood processing systems and methods convey blood cells from a blood cell source into a blood component collection flow channel that includes a blood cell storage container and an in-line filter to remove leukocytes from blood cells before entering the blood cell storage container. The systems and methods also convey additive solution from an additive solution source into the blood component collection flow channel. The systems and methods alternate the conveyance of blood cells through the filter with the conveyance of additive solution through the filter.

摘要翻译： 血液处理系统和方法将血液细胞从血细胞源传送到血液成分收集流通道中，该血液成分收集流通道包括血细胞储存容器和在线过滤器，以在进入血细胞储存容器之前从血液细胞中除去白细胞。 所述系统和方法还将添加剂溶液从添加剂溶液源输送到血液成分收集流动通道中。 系统和方法通过过滤器输送添加剂溶液来交替通过过滤器的血细胞的输送。