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公开(公告)号：US20210188930A1
公开(公告)日：2021-06-24
申请号：US16959906
申请日：2018-04-28
发明人： Min LU , Jiale WU , Huaxin SONG
IPC分类号： C07K14/47 , G01N33/68 , A61K45/06 , G01N33/574
摘要： Disclosed herein is a novel p53 complex and a collection of compounds that can tightly associate with p53 to efficiently rescue wildtype p53 structure and function, and the methods of making and using the complex and the compounds, including for diagnosis, prognosis, and treatment of p53 related disorders such as cancer and aging.
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公开(公告)号：US20220016147A1
公开(公告)日：2022-01-20
申请号：US17295494
申请日：2019-11-18
申请人： SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. , RUI JIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE
发明人： Weili ZHAO , Ting LIU , Xianping LU , Pengpeng XU , Xin FU
IPC分类号： A61K31/704 , A61K31/4406 , C07K16/28 , A61K31/675 , A61K31/475 , A61K31/573 , A61K45/06 , A61P35/00
摘要： The present application provides an application of Chidamide in combination with R-CHOP in preparing a drug used for treating B-cell lymphoma, and also provides a drug comprising Chidamide and R-CHOP. Chidamide in combination with R-CHOP has a synergistic therapeutic effect on B-cell lymphoma.
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公开(公告)号：US20210205260A1
公开(公告)日：2021-07-08
申请号：US16959894
申请日：2019-01-02
发明人： Min LU , Jiale WU , Huaxin SONG
IPC分类号： A61K31/285 , A61K31/29 , A61K33/36 , A61K33/245 , A61K33/243 , A61K45/06
摘要： Novel mp53 rescue compounds and the pharmaceutical composition, and methods of treating a p53 disorder.
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4.发明授权公开(公告)号：US09016025B2
公开(公告)日：2015-04-28
申请号：US14352023
申请日：2012-06-11
申请人： Rui Jin , Chuanming Zhai , Bo Chang , Qiang Hu , Fei Wu , Jinghui Ping , Wei Xu
发明人： Rui Jin , Chuanming Zhai , Bo Chang , Qiang Hu , Fei Wu , Jinghui Ping , Wei Xu
CPC分类号： E04G11/28 , E04B2/84 , E04G5/046 , E04G2003/286
摘要： A constructing method for a concrete cylinder of a construction steel bar of a high-rise steel structure adopts a constructing method of supporting inside and climbing outside. The outside of the cylinder adopts hydraulic mutual-climbing adhesive lifting scaffold creeping formwork system (100), and also has an outside wallboard mechanical formwork erection function and an outer frame protection function. For the inside of the cylinder, except that an appropriate structure is left for later processing according to a schedule requirement, beam walls all adopt a steel cylinder support to perform formwork erection, so as to greatly reduce the workload of repeatedly mounting/dismantling the scaffold and the formwork at a high place. The scaffold itself carries the formwork erection system, so formwork erection and formwork removal can be mechanized, thereby reducing the risk of formwork erection and formwork removal at a high place.
摘要翻译： 高层钢结构建筑钢筋混凝土柱体的施工方法采用了一种支撑在内外攀升的施工方法。 气缸外部采用液压爬升式粘合剂提升脚手架蠕动模板系统（100），还具有外墙板机械模板架设功能和外框保护功能。 对于气缸的内部，除了根据时间表要求进行后续处理的适当结构之外，梁壁均采用钢瓶支架进行模板架设，以大大减少反复安装/拆卸脚手架的工作量 和模具在高处。 脚手架本身具有模板架设系统，可以对模板架设和模板拆卸进行机械化，从而降低高层模板架设和模板拆卸的风险。
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公开(公告)号：US5795836A
公开(公告)日：1998-08-18
申请号：US907431
申请日：1997-08-07
申请人： Rui Jin , Kesen Zhao , Jun Liu , Yan Jin , Qin Lei , Xinnong Li
发明人： Rui Jin , Kesen Zhao , Jun Liu , Yan Jin , Qin Lei , Xinnong Li
CPC分类号： A61L15/18 , A61K33/24 , A61L15/08 , Y10T428/2927 , Y10T442/699
摘要： This invention concerns a medical non-woven fabric containing inorganic oxides complex powder. The inorganic oxides complex powder consists of 80-95% (weight) of TiO.sub.2, 2-10% (weight) of Al.sub.2 O.sub.3 and 1-10% (weight) of SiO.sub.2. This medical non-woven fabric can improve microcirculation remarkably and has special effect of dephlogistication, detumescence and speeding up healing of wounds. Thus, it is suitable for supplementary treatment of tumefaction, surface wounds and fracture.
摘要翻译： 本发明涉及含有无机氧化物复合粉末的医用无纺织物。 无机氧化物复合粉末由80-95％（重量）的TiO 2，2-10％（重量）的Al 2 O 3和1-10％（重量）的SiO 2组成。 这种医用非织造布可以显着改善微循环，并具有脱屑，消肿和加速伤口愈合的特殊效果。 因此，适用于补充治疗肿胀，表面伤口和骨折。
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6.发明申请公开(公告)号：US20200325156A1
公开(公告)日：2020-10-15
申请号：US16760779
申请日：2018-11-02
申请人： Rui Jin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine , Xiamen University
发明人： Ruibao Ren , Xianming Deng , Min Wu , Ting Zhang , Bo Jiao , Qiaofeng Kang , Wei Huang
IPC分类号： C07D513/04 , A61P35/00
摘要： The present invention relates to heteroaryl amide compounds, a preparation method therefor, pharmaceutical compositions thereof and applications thereof, and specifically, relates to a type of compounds having broad-spectrum tumor resistant activity, a preparation method therefor, pharmaceutical compositions containing the compounds, and uses of the compounds in the preparation of drugs for treating tumors.
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7.发明授权Superfine microelemental biochemical mixture and foamed plastic products thereof 失效超细微量元素生化混合物及其发泡塑料制品
公开(公告)号：US5599851A
公开(公告)日：1997-02-04
申请号：US522620
申请日：1995-09-01
申请人： Rui Jin , Jun Liu , Qibiao Yang
发明人： Rui Jin , Jun Liu , Qibiao Yang
CPC分类号： C08J9/0066 , C08K3/0075 , C08J2375/04
摘要： This invention relates to a kind of superfine microelemental biochemical mixture and its foamed plastic products. The mixture contains titanium oxide, zirconia, silica, yttrium oxide, cerium oxide, tin dioxide, silver phosphate and other microelements, and has certain impact on human body's micro-circulation. The plastic products comprise the mixture according to the invention and base materials which conventionally are used in preparation for foamed plastics.
摘要翻译： 本发明涉及一种超细微量元素生物化学混合物及其发泡塑料制品。 该混合物含有氧化钛，氧化锆，二氧化硅，氧化钇，氧化铈，二氧化锡，磷酸银等微量元素，对人体的微循环有一定的影响。 塑料制品包括根据本发明的混合物和常规用于制备发泡塑料的基材。
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8.发明申请公开(公告)号：US20140305070A1
公开(公告)日：2014-10-16
申请号：US14352023
申请日：2012-06-11
申请人： Rui Jin , Chuanming Zhai , Bo Chang , Qiang Hu , Fei WU , Jinghui Ping , Wei Xu
发明人： Rui Jin , Chuanming Zhai , Bo Chang , Qiang Hu , Fei WU , Jinghui Ping , Wei Xu
CPC分类号： E04G11/28 , E04B2/84 , E04G5/046 , E04G2003/286
摘要： A constructing method for a concrete cylinder of a construction steel bar of a high-rise steel structure adopts a constructing method of supporting inside and climbing outside. The outside of the cylinder adopts hydraulic mutual-climbing adhesive lifting scaffold creeping formwork system (100), and also has an outside wallboard mechanical formwork erection function and an outer frame protection function. For the inside of the cylinder, except that an appropriate structure is left for later processing according to a schedule requirement, beam walls all adopt a steel cylinder support to perform formwork erection, so as to greatly reduce the workload of repeatedly mounting/dismantling the scaffold and the formwork at a high place. The scaffold itself carries the formwork erection system, so formwork erection and formwork removal can be mechanized, thereby reducing the risk of formwork erection and formwork removal at a high place
摘要翻译： 高层钢结构建筑钢筋混凝土柱体的施工方法采用了一种支撑在内外攀升的施工方法。 气缸外部采用液压爬升式粘合剂提升脚手架蠕动模板系统（100），还具有外墙板机械模板架设功能和外框保护功能。 对于气缸的内部，除了根据时间表要求进行后续处理的适当结构之外，梁壁均采用钢瓶支架进行模板架设，以大大减少反复安装/拆卸脚手架的工作量 和模具在高处。 脚手架本身具有模板架设系统，可以对模板架设和模板拆卸进行机械化，从而降低高层模板架设和模板拆卸的风险
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