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公开(公告)号：US20120331580A1
公开(公告)日：2012-12-27
申请号：US13584087
申请日：2012-08-13
Applicant: Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale
Inventor： Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale
CPC classification number: C12N9/0069 , C12N15/00 , C12N15/01 , C12N15/09 , C12N15/8274 , C12Y113/11027
Abstract: Compositions and methods for conferring hydroxyphenyl pyruvate dioxygenase (HPPD) herbicide resistance or tolerance to plants are provided. Compositions include amino acid sequences, and variants and fragments thereof, for mutant HPPD polypeptides. Nucleic acids that encode the mutant HPPD polypeptides are also provided. Methods for conferring herbicide resistance or tolerance, particularly resistance or tolerance to certain classes of herbicides that inhibit HPPD, in plants are further provided. Methods are also provided for selectively controlling weeds in a field at a crop locus and for the assay, characterization, identification and selection of the mutant HPPDs of the current invention that provide herbicide tolerance.
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公开(公告)号：US09347046B2
公开(公告)日：2016-05-24
申请号：US12838387
申请日：2010-07-16
Applicant: Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale , Shradha Singh , Vance Kramer
Inventor： Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale , Shradha Singh , Vance Kramer
IPC: A01H5/00 , A01H5/10 , C12N15/01 , C12N15/82 , C12N15/63 , C12N9/02 , C12N15/29 , A01N25/00 , C12N15/09
CPC classification number: C12N9/0069 , A01N41/10 , A01N43/40 , A01N43/80 , C12N9/0004 , C12N9/0073 , C12N15/09 , C12N15/8274 , C12Y113/11027
Abstract: Novel hydroxyphenyl pyruvate dioxygenase (HPPD) polypeptides, variants and fragments thereof, as well as polynucleotides encoding the same, capable of conferring commercial levels of conferring HPPD herbicide resistance or tolerance to plants. Compositions include amino acid sequences, and variants and fragments thereof, for HPPD polypeptides, as well as polynucleotides encoding the same. Methods for the production and use of HPPD herbicide resistant plants that express these novel HPPD polypeptides, methods for selectively controlling weeds in a field at a crop locus, and methods for the assay, characterization, identification and selection of these novel HPPDs are also provided.
Abstract translation: 新型羟基苯基丙酮酸双加氧酶（HPPD）多肽，其变体和片段，以及编码该多肽的多核苷酸，能赋予赋予植物HPPD除草剂抗性或耐受性的商业水平。 组合物包括用于HPPD多肽的氨基酸序列及其变体和片段，以及编码该多肽的多核苷酸。 还提供了用于生产和使用表达这些新型HPPD多肽的HPPD除草剂抗性植物的方法，在作物基因座上选择性控制杂草的方法，以及用于测定，表征，鉴定和选择这些新型HPPD的方法。
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公开(公告)号：US08188053B2
公开(公告)日：2012-05-29
申请号：US12086210
申请日：2006-12-04
Applicant: Marie Cumberbatch , Rebecca Jane Dearman , Ian Kimber , Russell Colin Viner
Inventor： Marie Cumberbatch , Rebecca Jane Dearman , Ian Kimber , Russell Colin Viner
CPC classification number: C12N9/0036 , A61K38/00
Abstract: The present invention relates, inter alia, to a method of ameliorating an inflammatory skin condition. Thus, the present invention provides a peptide that includes the amino acid sequence KMIKP (SEQ ID NO: 20), wherein the peptide includes no more than 70 amino acids and wherein the peptide is capable of inhibiting allergen induced Langerhans cell migration, and wherein the peptide is not that depicted in SEQ ID NO. 19. The present invention also relates to the use of a peptide that includes the amino acid sequence KMIKP (SEQ ID NO: 20), wherein the peptide includes no more than 100 amino acids, and wherein the peptide is capable of inhibiting allergen induced Langerhans cell migration, in the manufacture of a topical medicament for the treatment of an inflammatory skin condition.
Abstract translation: 本发明尤其涉及一种改善炎性皮肤病症的方法。 因此，本发明提供了包含氨基酸序列KMIKP（SEQ ID NO：20）的肽，其中所述肽包含不超过70个氨基酸，并且其中所述肽能够抑制变应原诱导的朗格汉斯细胞迁移，并且其中 肽不是SEQ ID NO： 本发明还涉及包含氨基酸序列KMIKP（SEQ ID NO：20）的肽的用途，其中所述肽包含不超过100个氨基酸，并且其中所述肽能够抑制变应原诱导的朗格汉斯 在制备用于治疗炎性皮肤病症的局部药物中的细胞迁移。
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公开(公告)号：US09074177B2
公开(公告)日：2015-07-07
申请号：US13570551
申请日：2012-08-09
Applicant: Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale
Inventor： Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale
IPC: A01H5/00 , A01H5/10 , C12N15/01 , C12N15/63 , C12N9/02 , C12N15/29 , A01N25/00 , C12N15/09 , C12N15/00 , C12N15/82
CPC classification number: C12N9/0069 , C12N15/00 , C12N15/01 , C12N15/09 , C12N15/8274 , C12Y113/11027
Abstract: Compositions and methods for conferring hydroxyphenyl pyruvate dioxygenase (HPPD) herbicide resistance or tolerance to plants are provided. Compositions include amino acid sequences, and variants and fragments thereof, for mutant HPPD polypeptides. Nucleic acids that encode the mutant HPPD polypeptides are also provided. Methods for conferring herbicide resistance or tolerance, particularly resistance or tolerance to certain classes of herbicides that inhibit HPPD, in plants are further provided. Methods are also provided for selectively controlling weeds in a field at a crop locus and for the assay, characterization, identification and selection of the mutant HPPDs of the current invention that provide herbicide tolerance.
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公开(公告)号：US09051300B2
公开(公告)日：2015-06-09
申请号：US13388233
申请日：2010-07-29
Applicant: Stephane André Marie Jeanmart , Adrian Longstaff , Christopher John Mathews , Claire Janet Russell , Russell Colin Viner , Frances Kathryn Wood
Inventor： Stephane André Marie Jeanmart , Adrian Longstaff , Christopher John Mathews , Claire Janet Russell , Russell Colin Viner , Frances Kathryn Wood
IPC: C07D277/24 , A01N43/78 , C07D405/08 , A01N43/10 , A01N43/54 , A01N43/56 , C07D401/08 , C07D409/08 , C07D417/08 , C07D417/14
CPC classification number: C07D405/08 , A01N43/10 , A01N43/54 , A01N43/56 , A01N43/78 , C07D401/08 , C07D409/08 , C07D417/08 , C07D417/14
Abstract: The invention relates to a compound of formula (I), which is suitable for use as a herbicide wherein G is hydrogen or an agriculturally acceptable metal, sulfonium, ammonium or latentiating group; Q is a unsubstituted or substituted C3-C8 saturated or mono-unsaturated heterocyclyl containing at least one heteroatom selected from O, N and S, or Q is heteroaryl or substituted heteroaryl; m is 1, 2 or 3; and Het is an optionally substituted monocyclic or bicyclic heteroaromatic ring; and wherein the compound is optionally an agronomically acceptable salt thereof.
Abstract translation: 本发明涉及式（I）化合物，其适用作除草剂，其中G为氢或农业上可接受的金属，锍，铵或潜伏基; Q是含有至少一个选自O，N和S的杂原子，或Q是杂芳基或取代的杂芳基的未取代或取代的C3-C8饱和或单不饱和杂环基; m为1,2或3; Het是任选取代的单环或双环杂芳环; 并且其中所述化合物任选为其农学上可接受的盐。
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Patent Agency Ranking
6.发明申请MUTANT HYDROXYPHENYLPYRUVATE DIOXYGENASE POLYPEPTIDES AND METHODS OF USE 审中-公开突变型羟基苯甲酰基二异氰酸酯多糖及其使用方法公开(公告)号：US20120311738A1
公开(公告)日：2012-12-06
申请号：US13570489
申请日：2012-08-09
Applicant: Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale
Inventor： Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale
IPC: C12N15/53 , C12N5/10 , A01H5/00 , A01P13/00 , A01H5/10 , A01N43/40 , A01N35/06 , A01N37/34 , C12N15/82 , A01H1/06
CPC classification number: C12N9/0069 , C12N15/00 , C12N15/01 , C12N15/09 , C12N15/8274 , C12Y113/11027
Abstract: Compositions and methods for conferring hydroxyphenyl pyruvate dioxygenase (HPPD) herbicide resistance or tolerance to plants are provided. Compositions include amino acid sequences, and variants and fragments thereof, for mutant HPPD polypeptides. Nucleic acids that encode the mutant HPPD polypeptides are also provided. Methods for conferring herbicide resistance or tolerance, particularly resistance or tolerance to certain classes of herbicides that inhibit HPPD, in plants are further provided. Methods are also provided for selectively controlling weeds in a field at a crop locus and for the assay, characterization, identification and selection of the mutant HPPDs of the current invention that provide herbicide tolerance.
Abstract translation: 提供了赋予植物抗性或抗性的羟基苯基丙酮酸双加氧酶（HPPD）除草剂的组合物和方法。 组合物包括突变体HPPD多肽的氨基酸序列及其变体和片段。 还提供了编码突变体HPPD多肽的核酸。 还提供了在植物中赋予除草剂抗性或耐受性，特别是对某些类别的抑制HPPD的除草剂的抗性或耐受性的方法。 还提供了用于选择性地控制在作物基因座的田地中的杂草以及提供除草剂耐受性的本发明的突变体HPPDs的测定，表征，鉴定和选择的方法。
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7.发明申请公开(公告)号：US20100197503A1
公开(公告)日：2010-08-05
申请号：US12692552
申请日：2010-01-22
Applicant: Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale
Inventor： Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale
CPC classification number: C12N9/0069 , C12N15/00 , C12N15/01 , C12N15/09 , C12N15/8274 , C12Y113/11027
Abstract: Compositions and methods for conferring hydroxyphenyl pyruvate dioxygenase (HPPD) herbicide resistance or tolerance to plants are provided. Compositions include amino acid sequences, and variants and fragments thereof, for mutant HPPD polypeptides. Nucleic acids that encode the mutant HPPD polypeptides are also provided. Methods for conferring herbicide resistance or tolerance, particularly resistance or tolerance to certain classes of herbicides that inhibit HPPD, in plants are further provided. Methods are also provided for selectively controlling weeds in a field at a crop locus and for the assay, characterization, identification and selection of the mutant HPPDs of the current invention that provide herbicide tolerance.
Abstract translation: 提供了赋予植物抗性或抗性的羟基苯基丙酮酸双加氧酶（HPPD）除草剂的组合物和方法。 组合物包括突变体HPPD多肽的氨基酸序列及其变体和片段。 还提供了编码突变体HPPD多肽的核酸。 还提供了在植物中赋予除草剂抗性或耐受性，特别是对某些类别的抑制HPPD的除草剂的抗性或耐受性的方法。 还提供了用于选择性地控制在作物基因座的田地中的杂草以及提供除草剂耐受性的本发明的突变型HPPDs的测定，表征，鉴定和选择的方法。
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公开(公告)号：US20090253631A1
公开(公告)日：2009-10-08
申请号：US12086210
申请日：2006-12-04
Applicant: Marie Cumberbatch , Rebecca Jane Dearman , Ian Kimber , Russell Colin Viner
Inventor： Marie Cumberbatch , Rebecca Jane Dearman , Ian Kimber , Russell Colin Viner
CPC classification number: C12N9/0036 , A61K38/00
Abstract: The present invention relates, inter alia, to a method of ameliorating an inflammatory skin condition. Thus, the present invention provides a peptide that includes the amino acid sequence KMIKP (SEQ ID NO: 20), wherein the peptide includes no more than 70 amino acids and wherein the peptide is capable of inhibiting allergen induced Langerhans cell migration, and wherein the peptide is not that depicted in SEQ ID NO. 19. The present invention also relates to the use of a peptide that includes the amino acid sequence KMIKP (SEQ ID NO: 20), wherein the peptide includes no more than 100 amino acids, and wherein the peptide is capable of inhibiting allergen induced Langerhans cell migration, in the manufacture of a topical medicament for the treatment of an inflammatory skin condition.
Abstract translation: 本发明尤其涉及一种改善炎性皮肤病症的方法。 因此，本发明提供了包含氨基酸序列KMIKP（SEQ ID NO：20）的肽，其中所述肽包含不超过70个氨基酸，并且其中所述肽能够抑制变应原诱导的朗格汉斯细胞迁移，并且其中 肽不是SEQ ID NO： 本发明还涉及包含氨基酸序列KMIKP（SEQ ID NO：20）的肽的用途，其中所述肽包含不超过100个氨基酸，并且其中所述肽能够抑制变应原诱导的朗格汉斯 在制备用于治疗炎性皮肤病症的局部药物中的细胞迁移。
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公开(公告)号：US09388393B2
公开(公告)日：2016-07-12
申请号：US13584087
申请日：2012-08-13
Applicant: Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale
Inventor： Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale
IPC: A01H5/00 , A01H5/10 , C12N15/82 , C12N15/53 , C12N9/04 , C12N9/02 , C12N15/01 , C12N15/09 , C12N15/00
CPC classification number: C12N9/0069 , C12N15/00 , C12N15/01 , C12N15/09 , C12N15/8274 , C12Y113/11027
Abstract: Compositions and methods for conferring hydroxyphenyl pyruvate dioxygenase (HPPD) herbicide resistance or tolerance to plants are provided. Compositions include amino acid sequences, and variants and fragments thereof, for mutant HPPD polypeptides. Nucleic acids that encode the mutant HPPD polypeptides are also provided. Methods for conferring herbicide resistance or tolerance, particularly resistance or tolerance to certain classes of herbicides that inhibit HPPD, in plants are further provided. Methods are also provided for selectively controlling weeds in a field at a crop locus and for the assay, characterization, identification and selection of the mutant HPPDs of the current invention that provide herbicide tolerance.
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公开(公告)号：US09057050B2
公开(公告)日：2015-06-16
申请号：US13572993
申请日：2012-08-13
Applicant: Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale
Inventor： Timothy Robert Hawkes , Michael Phillip Langford , Russell Colin Viner , Bernardus Theodorus Maria Vernooij , Richard Dale
IPC: A01H5/00 , A01H5/10 , C12N15/01 , C12N15/82 , C12N15/63 , C12N9/02 , C12N15/29 , A01N25/00 , C12N15/09 , C12N15/00
CPC classification number: C12N9/0069 , C12N15/00 , C12N15/01 , C12N15/09 , C12N15/8274 , C12Y113/11027
Abstract: Compositions and methods for conferring hydroxyphenyl pyruvate dioxygenase (HPPD) herbicide resistance or tolerance to plants are provided. Compositions include amino acid sequences, and variants and fragments thereof, for mutant HPPD polypeptides. Nucleic acids that encode the mutant HPPD polypeptides are also provided. Methods for conferring herbicide resistance or tolerance, particularly resistance or tolerance to certain classes of herbicides that inhibit HPPD, in plants are further provided. Methods are also provided for selectively controlling weeds in a field at a crop locus and for the assay, characterization, identification and selection of the mutant HPPDs of the current invention that provide herbicide tolerance.
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