公开(公告)号：US20110302390A1

公开(公告)日：2011-12-08

申请号：US12794725

申请日：2010-06-05

申请人： Greg Copeland ,  Shehrzad Qureshi

发明人： Greg Copeland ,  Shehrzad Qureshi

IPC分类号： G06F15/76

CPC分类号： G06F9/5061 ,  H04B1/0003

摘要： Systems and methods for performing processing of communications signals on multi-processor architectures. The system consists of a digital interface that translate numbers that represent a waveform in some format to analog signals for use in transmission and translating analog signals to numbers representing those waveforms in some format that can be processed by the commodity digital hardware and software combination. The digital hardware and software incorporates parallel hardware and software that can process single or multiple streams and multiple processing steps as required for the communications system in any combination. In the examples, the use of general purpose graphics processing units (GPGPUs) is illustrated, but the system is not necessarily limited to such an implementation. The system is highly scalable and modular for addressing a wide range of radio requirements, preferably using commodity components.

摘要翻译： 用于在多处理器架构上执行通信信号处理的系统和方法。 该系统包括一个数字接口，将代表某种格式的波形的数字转换为模拟信号，用于传输，并将模拟信号转换为表示可由商品数字硬件和软件组合处理的某些格式的波形的数字。 数字硬件和软件并入并行硬件和软件，可以以任何组合处理通信系统所需的单个或多个流和多个处理步骤。 在示例中，示出了使用通用图形处理单元（GPGPU），但是系统不一定限于这样的实现。 该系统是高度可扩展性和模块化的，用于满足广泛的无线电需求，优选使用商品组件。

公开(公告)号：US20050047544A1

公开(公告)日：2005-03-03

申请号：US10652786

申请日：2003-08-29

申请人： Dongshan Fu ,  Gopinath Kuduvalli ,  Shehrzad Qureshi

发明人： Dongshan Fu ,  Gopinath Kuduvalli ,  Shehrzad Qureshi

IPC分类号： A61N5/10 ,  G01N23/04 ,  G06T7/00 ,  G06T7/20 ,  G09G5/00

CPC分类号： A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1061 ,  A61N2005/1062 ,  G01N23/04 ,  G06T7/254 ,  G06T7/32 ,  G06T7/38 ,  G06T2207/10124 ,  G06T2207/30004

摘要： A method and system is provided for registering a 2D radiographic image of a target with previously generated 3D scan data of the target. A reconstructed 2D image is generated from the 3D scan data. The radiographic 2D image is registered with the reconstructed 2D images to determine the values of in-plane transformation parameters (x, y, θ) and out-of-plane rotational parameters (r, φ), where the parameters represent the difference in the position of the target in the radiographic image, as compared to the 2D reconstructed image. An initial estimate for the in-plane transformation parameters is made by a 3D multi-level matching process, using the sum-of-square differences similarity measure. Based on these estimated parameters, an initial 1-D search is performed for the out-of-plane rotation parameters (r, φ), using a pattern intensity similarity measure. The in-plane parameters (x, y, θ) and the out-of-plane parameters (r, φ) are iteratively refined, until a desired accuracy is reached.

摘要翻译： 提供了一种方法和系统，用于将目标的2D放射线照相图像与先前生成的目标的3D扫描数据进行注册。 从3D扫描数据生成重建的2D图像。 射线照相2D图像与重建的2D图像一起记录，以确定面内变换参数（x，y，θ）和平面外旋转参数（r，phi）的值，其中参数表示 与2D重建图像相比，放射线照相图像中的目标的位置。 通过3D多级匹配过程，使用平方和差异相似性度量来进行面内变换参数的初始估计。 基于这些估计的参数，使用模式强度相似性度量对面外旋转参数（r，phi）执行初始1-D搜索。 平面内参数（x，y，θ）和平面外参数（r，phi）被迭代地改进，直到达到期望的精度。

公开(公告)号：US20060071983A1

公开(公告)日：2006-04-06

申请号：US10956616

申请日：2004-10-01

申请人： Richard Stearns ,  Shehrzad Qureshi

发明人： Richard Stearns ,  Shehrzad Qureshi

IPC分类号： B41J2/045

CPC分类号： B05B12/004 ,  B01J2219/00362 ,  B01J2219/00378 ,  B01J2219/00527 ,  B01J2219/00677 ,  B01L3/0268 ,  B01L2200/143 ,  B01L2200/148 ,  B01L2300/0819 ,  B01L2400/0436 ,  B01L2400/0439 ,  B41J2/04541 ,  B41J2/04563 ,  B41J2/04575 ,  B41J2/0458 ,  B41J2/14008

摘要： The invention provides apparatuses and methods for acoustically ejecting the fluid from a reservoir contained in or disposed on a substrate. The reservoir has a portion adapted to contain a fluid, and an acoustic radiation generator is positioned in acoustic coupling relationship to the reservoir. Acoustic radiation generated by the acoustic radiation generator is transmitted through at least the portion of the reservoir to an analyzer. The analyzer is capable of determining the energy level of the transmitted acoustic radiation and raising the energy level of subsequent pulses to a level sufficient to eject fluid droplets from the reservoir. The invention is particularly suited for delivering fluid from a plurality of reservoirs in an accurate and efficient manner.

摘要翻译： 本发明提供了用于从包含在或设置在基板上的储存器中喷射流体的装置和方法。 储存器具有适于容纳流体的部分，并且声辐射发生器被定位成与储存器的声耦合关系。 由声辐射发生器产生的声辐射通过至少一部分储存器传输到分析器。 分析仪能够确定所发射的声辐射的能量水平，并且将后续脉冲的能量水平提高到足以从储存器喷射流体液滴的水平。 本发明特别适用于以准确和有效的方式从多个储层输送流体。

公开(公告)号：US20050049478A1

公开(公告)日：2005-03-03

申请号：US10652785

申请日：2003-08-29

申请人： Gopinath Kuduvalli ,  Dongshan Fu ,  Shehrzad Qureshi

发明人： Gopinath Kuduvalli ,  Dongshan Fu ,  Shehrzad Qureshi

IPC分类号： A61N5/10 ,  G01N23/04 ,  G06T7/00 ,  G06T7/20 ,  A61B5/05

CPC分类号： A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1061 ,  A61N2005/1062 ,  G01N23/04 ,  G06T7/254 ,  G06T7/32 ,  G06T7/38 ,  G06T2207/10124 ,  G06T2207/30004

摘要： An image-guided radiosurgery method and system are presented that use 2D/3D image registration to keep the radiosurgical beams properly focused onto a treatment target. A pre-treatment 3D scan of the target is generated at or near treatment planning time. A set of 2D DRRs are generated, based on the pre-treatment 3D scan. At least one 2D x-ray image of the target is generated in near real time during treatment. The DRRs are registered with the x-ray images, by computing a set of 3D transformation parameters that represent the change in target position between the 3D scan and the x-ray images. The relative position of the radiosurgical beams and the target is continuously adjusted in near real time in accordance with the 3D transformation parameters. A hierarchical and iterative 2D/3D registration algorithm is used, in which the transformation parameters that are in-plane with respect to the image plane of the x-ray images are computed separately from the out-of-plane transformation parameters.

摘要翻译： 提出了一种使用2D / 3D图像配准的图像引导放射外科手术方法和系统，将放射外科手术束适当地聚焦到治疗目标上。 在治疗计划时间或附近产生目标的预处理3D扫描。 基于预处理3D扫描生成一组2D DRR。 在治疗期间，近乎实时地产生目标的至少一个2D X射线图像。 通过计算表示3D扫描和X射线图像之间的目标位置的变化的一组3D变换参数，向X射线图像登记DRR。 根据3D变换参数，放射外科手术束和目标物的相对位置以近实时的方式连续调整。 使用分层和迭代的2D / 3D注册算法，其中相对于x射线图像的像面在平面内的变换参数与面外变换参数分开计算。

公开(公告)号：US20100239153A1

公开(公告)日：2010-09-23

申请号：US12793621

申请日：2010-06-03

申请人： Gopinath Kuduvalli ,  Dongshan Fu ,  Shehrzad Qureshi

发明人： Gopinath Kuduvalli ,  Dongshan Fu ,  Shehrzad Qureshi

IPC分类号： G06K9/00

CPC分类号： A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1061 ,  A61N2005/1062 ,  G01N23/04 ,  G06T7/254 ,  G06T7/32 ,  G06T7/38 ,  G06T2207/10124 ,  G06T2207/30004

摘要： A set of 2D reconstructed images is generated from a pretreatment 3D scan showing an initial position of a target, wherein the set of 2D reconstructed images corresponds to perturbations from said initial position along fewer than six degrees of freedom. Said set of 2D reconstructed images are registered with one or more 2D x-ray images of said target showing a current position of the target, wherein the registering includes computing a set of 3D transformation parameters that represent a change in position of said target between said initial position of said pretreatment 3D scan and said current position of said 2D x-ray images along six degrees of freedom. A positioning system is instructed to adjust a relative position of a radiosurgical beam generator to said target by an amount prescribed by said 3D transformation parameters, wherein said target is allowed six degrees of freedom of position

摘要翻译： 从显示目标的初始位置的预处理3D扫描产生一组2D重建图像，其中所述一组2D重建图像对应于沿着少于六个自由度的所述初始位置的扰动。 所述一组2D重建图像与所述目标的当前位置的一个或多个2D X射线图像一起登记，其中所述注册包括计算一组3D变换参数，所述三维变换参数表示所述目标在所述目标位置之间的位置变化 所述预处理3D扫描的初始位置和所述2D X射线图像的当前位置沿着六个自由度。 指示定位系统将放射外科手术束发生器相对于所述目标的相对位置调整为由所述3D变换参数规定的量，其中所述目标被允许六个位置的自由度

公开(公告)号：US07756567B2

公开(公告)日：2010-07-13

申请号：US10652785

申请日：2003-08-29

申请人： Gopinath Kuduvalli ,  Dongshan Fu ,  Shehrzad Qureshi

发明人： Gopinath Kuduvalli ,  Dongshan Fu ,  Shehrzad Qureshi

IPC分类号： A61B5/05

CPC分类号： A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1061 ,  A61N2005/1062 ,  G01N23/04 ,  G06T7/254 ,  G06T7/32 ,  G06T7/38 ,  G06T2207/10124 ,  G06T2207/30004

摘要： An image-guided radiosurgery method and system are presented that use 2D/3D image registration to keep the radiosurgical beams properly focused onto a treatment target. A pre-treatment 3D scan of the target is generated at or near treatment planning time. A set of 2D DRRs are generated, based on the pre-treatment 3D scan. At least one 2D x-ray image of the target is generated in near real time during treatment. The DRRs are registered with the x-ray images, by computing a set of 3D transformation parameters that represent the change in target position between the 3D scan and the x-ray images. The relative position of the radiosurgical beams and the target is continuously adjusted in near real time in accordance with the 3D transformation parameters. A hierarchical and iterative 2D/3D registration algorithm is used, in which the transformation parameters that are in-plane with respect to the image plane of the x-ray images are computed separately from the out-of-plane transformation parameters.

摘要翻译： 提出了一种使用2D / 3D图像配准的图像引导放射外科手术方法和系统，将放射外科手术束适当地聚焦到治疗目标上。 在治疗计划时间或附近产生目标的预处理3D扫描。 基于预处理3D扫描生成一组2D DRR。 在治疗期间，近乎实时地产生目标的至少一个2D X射线图像。 通过计算表示3D扫描和X射线图像之间的目标位置的变化的一组3D变换参数，向X射线图像登记DRR。 根据3D变换参数，放射外科手术束和目标物的相对位置以近实时的方式连续调整。 使用分层和迭代的2D / 3D注册算法，其中相对于x射线图像的像面在平面内的变换参数与面外变换参数分开计算。

公开(公告)号：US08280491B2

公开(公告)日：2012-10-02

申请号：US12793621

申请日：2010-06-03

申请人： Gopinath Kuduvalli ,  Dongshan Fu ,  Shehrzad Qureshi

发明人： Gopinath Kuduvalli ,  Dongshan Fu ,  Shehrzad Qureshi

IPC分类号： A61B5/05

CPC分类号： A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1061 ,  A61N2005/1062 ,  G01N23/04 ,  G06T7/254 ,  G06T7/32 ,  G06T7/38 ,  G06T2207/10124 ,  G06T2207/30004

摘要： A set of 2D reconstructed images is generated from a pretreatment 3D scan showing an initial position of a target, wherein the set of 2D reconstructed images corresponds to perturbations from said initial position along fewer than six degrees of freedom. Said set of 2D reconstructed images are registered with one or more 2D x-ray images of said target showing a current position of the target, wherein the registering includes computing a set of 3D transformation parameters that represent a change in position of said target between said initial position of said pretreatment 3D scan and said current position of said 2D x-ray images along six degrees of freedom. A positioning system is instructed to adjust a relative position of a radiosurgical beam generator to said target by an amount prescribed by said 3D transformation parameters, wherein said target is allowed six degrees of freedom of position.

摘要翻译： 从显示目标的初始位置的预处理3D扫描产生一组2D重建图像，其中所述一组2D重建图像对应于沿着少于6个自由度的所述初始位置的扰动。 所述一组2D重建图像与所述目标的当前位置的一个或多个2D X射线图像一起登记，其中所述注册包括计算一组3D变换参数，所述三维变换参数表示所述目标在所述目标位置之间的位置变化 所述预处理3D扫描的初始位置和所述2D X射线图像的当前位置沿着六个自由度。 指示定位系统将放射外科手术束发生器相对于所述目标的相对位置调整由所述3D变换参数规定的量，其中所述目标被允许六个位置自由度。

公开(公告)号：US07204640B2

公开(公告)日：2007-04-17

申请号：US10652786

申请日：2003-08-29

申请人： Dongshan Fu ,  Gopinath Kuduvalli ,  Shehrzad Qureshi

发明人： Dongshan Fu ,  Gopinath Kuduvalli ,  Shehrzad Qureshi

IPC分类号： A61N5/10

CPC分类号： A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1061 ,  A61N2005/1062 ,  G01N23/04 ,  G06T7/254 ,  G06T7/32 ,  G06T7/38 ,  G06T2207/10124 ,  G06T2207/30004

摘要： A method and system is provided for registering a 2D radiographic image of a target with previously generated 3D scan data of the target. A reconstructed 2D image is generated from the 3D scan data. The radiographic 2D image is registered with the reconstructed 2D images to determine the values of in-plane transformation parameters (x, y, θ) and out-of-plane rotational parameters (r, Φ), where the parameters represent the difference in the position of the target in the radiographic image, as compared to the 2D reconstructed image. An initial estimate for the in-plane transformation parameters is made by a 3D multi-level matching process, using the sum-of-square differences similarity measure. Based on these estimated parameters, an initial 1-D search is performed for the out-of-plane rotation parameters (r, Φ), using a pattern intensity similarity measure. The in-plane parameters (x, y, θ) and out-of-plane parameters (r, Φ) are iteratively refined, until a desired accuracy is reached.

摘要翻译： 提供了一种方法和系统，用于将目标的2D放射线照相图像与先前生成的目标的3D扫描数据进行注册。 从3D扫描数据生成重建的2D图像。 射线照相2D图像与重构的2D图像一起记录，以确定面内变换参数（x，y，θ）和平面外旋转参数（r，Phi）的值，其中参数表示 与2D重建图像相比，放射线照相图像中的目标的位置。 通过3D多级匹配过程，使用平方和差异相似性度量来进行面内变换参数的初始估计。 基于这些估计的参数，使用模式强度相似性度量对面外旋转参数（r，Phi）执行初始1-D搜索。 平面内参数（x，y，θ）和平面外参数（r，Phi）被迭代地改进，直到达到期望的精度。