MULTIMERIC FORMS OF ANTIMICROBIAL PEPTIDES
    1.
    发明申请
    MULTIMERIC FORMS OF ANTIMICROBIAL PEPTIDES 有权
    抗微生物肽的多形式

    公开(公告)号:US20110039760A1

    公开(公告)日:2011-02-17

    申请号:US12988994

    申请日:2009-04-21

    摘要: The invention relates to multimeric forms of antimicrobial peptides, for example, defensin peptides. The multimeric forms of defensin peptides possesses antimicrobial activity and may be formulated into antimicrobial compositions, pharmaceutical compositions, eyedrop composition, contact lens solution compositions for coating medical devices and the like. The invention also relates to the use of these multimeric forms of peptides, e.g. multimeric forms of defensin peptides for inhibiting and/or reducing the growth of microorganisms in general, including in a host. The invention further relates to a method of preparing multimers of peptides derived from defensins, for example hBD3.

    摘要翻译: 本发明涉及多聚体形式的抗微生物肽,例如防御素肽。 防御素肽的多聚体形式具有抗微生物活性,并且可以配制成抗微生物组合物,药物组合物,滴眼剂组合物,用于涂覆医疗装置的隐形眼镜溶液组合物等。 本发明还涉及这些多聚体形式的肽的用途,例如, 用于抑制和/或减少微生物生长的多聚体形式的防御素肽通常包括在宿主中。 本发明还涉及制备衍生自防御素例如hBD3的肽的多聚体的方法。

    Multimeric forms of antimicrobial peptides
    5.
    发明授权
    Multimeric forms of antimicrobial peptides 有权
    多聚体形式的抗微生物肽

    公开(公告)号:US08809262B2

    公开(公告)日:2014-08-19

    申请号:US12988994

    申请日:2009-04-21

    IPC分类号: A61K38/00 C07K1/00

    摘要: The invention relates to multimeric forms of antimicrobial peptides, for example, defensin peptides. The multimeric forms of defensin peptides possesses antimicrobial activity and may be formulated into antimicrobial compositions, pharmaceutical compositions, eyedrop composition, contact lens solution compositions for coating medical devices and the like. The invention also relates to the use of these multimeric forms of peptides, e.g. multimeric forms of defensin peptides for inhibiting and/or reducing the growth of microorganisms in general, including in a host. The invention further relates to a method of preparing multimers of peptides derived from defensins, for example hBD3.

    摘要翻译: 本发明涉及多聚体形式的抗微生物肽,例如防御素肽。 防御素肽的多聚体形式具有抗微生物活性,并且可以配制成抗微生物组合物,药物组合物,滴眼剂组合物,用于涂覆医疗装置的隐形眼镜溶液组合物等。 本发明还涉及这些多聚体形式的肽的用途,例如, 用于抑制和/或减少微生物生长的多聚体形式的防御素肽通常包括在宿主中。 本发明还涉及制备衍生自防御素例如hBD3的肽的多聚体的方法。