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1.发明授权Neurite elongation agent, memory-improving agent and anti-Alzheimer agent comprising 4′-demethylnobiletin or 4′-demethyltangeretin as active ingredient, and process for production of the compound 有权神经突伸剂，记忆改善剂和包含4'-去甲基异烟肼或4'-去甲基倍他宁作为活性成分的抗阿尔茨海默病药，以及该化合物的制备方法公开(公告)号：US08940789B2
公开(公告)日：2015-01-27
申请号：US13321988
申请日：2010-03-10
申请人： Shuichi Kusano , Hiroshi Tamura
发明人： Shuichi Kusano , Hiroshi Tamura
IPC分类号： A61K31/352 , A61P25/00 , A61P25/28 , C12P17/06 , C07D311/30 , A61K36/062 , A61K36/752
CPC分类号： C12P17/06 , A61K31/352 , A61K36/062 , A61K36/752 , C07D311/30 , A61K2300/00
摘要： A method for producing 4′-demethylnobiletin or 4′-demethyltangeretin including fermenting a skin derived from at least one citrus fruit selected from citrus fruits belonging to section Acrumen in subgenus Metacitrus in genus Citrus or citrus fruits belonging to section Aurantium in subgenus Archicitrus in genus Citrus, or a water extract product thereof using one or more Aspergillus molds selected from Aspergillus kawachii, Aspergillus awamori, Aspergillus oryzae, Aspergillus sojae, Aspergillus saitoi, and Aspergillus usamii to obtain a fermented product.
摘要翻译： 包括发酵至少一种柑橘类水果的皮肤的发酵方法，所述柑橘类水果选自属于属于属于属于属柑橘属亚属的柑橘类水果的柑橘类水果或属于亚属亚属中的to属部分的柑橘类水果 柑橘或其水提取产物，其使用选自曲霉（Aspergillus kawachii），泡盛曲霉（Aspergillus awamori），米曲霉（Aspergillus sojae），曲霉（Aspergillus sojae），saperi Aspergillus saitoi和美国曲霉（Aspergillus usamii）的一种或多种曲霉属霉菌，以获得发酵产物。
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2.发明申请NEURITE ELONGATION AGENT, MEMORY-IMPROVING AGENT AND ANTI-ALZHEIMER AGENT COMPRISING 4'-DEMETHYLNOBILETIN OR 4'-DEMETHYLTANGERETIN AS ACTIVE INGREDIENT, AND PROCESS FOR PRODUCTION OF THE COMPOUND 有权神经延长剂，记忆改良剂和包含4'-去甲基胆碱或4'-去甲肾上腺素作为活性成分的抗 - 阿尔茨海默剂，以及该化合物的生产方法公开(公告)号：US20120101152A1
公开(公告)日：2012-04-26
申请号：US13321988
申请日：2010-03-10
申请人： Shuichi Kusano , Hiroshi Tamura
发明人： Shuichi Kusano , Hiroshi Tamura
IPC分类号： A61K31/352 , A61P25/00 , A61P25/28 , C12P17/06 , C07D311/30
CPC分类号： C12P17/06 , A61K31/352 , A61K36/062 , A61K36/752 , C07D311/30 , A61K2300/00
摘要： A method for producing 4′-demethylnobiletin or 4′-demethyltangeretin including fermenting a skin derived from at least one citrus fruit selected from citrus fruits belonging to section Acrumen in subgenus Metacitrus in genus Citrus or citrus fruits belonging to section Aurantium in subgenus Archicitrus in genus Citrus, or a water extract product thereof using one or more Aspergillus molds selected from Aspergillus kawachii, Aspergillus awamori, Aspergillus oryzae, Aspergillus sojae, Aspergillus saitoi, and Aspergillus usamii to obtain a fermented product.
摘要翻译： 包括发酵至少一种柑橘类水果的皮肤的发酵方法，所述柑橘类水果选自属于属于属于属于属柑橘属亚属的柑橘类水果的柑橘类水果或属于亚属亚属中的to属部分的柑橘类水果 柑橘或其水提取产物，其使用选自曲霉（Aspergillus kawachii），泡盛曲霉（Aspergillus awamori），米曲霉（Aspergillus sojae），曲霉（Aspergillus sojae），saperi Aspergillus saitoi和美国曲霉（Aspergillus usamii）的一种或多种曲霉属霉菌，以获得发酵产物。
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3.发明申请公开(公告)号：US20120027914A1
公开(公告)日：2012-02-02
申请号：US13201906
申请日：2010-02-15
CPC分类号： C12R1/25 , A23L27/24 , A23L33/105 , A61K36/8962 , C12N1/20 , A61K2300/00
摘要： A fermentation product (fermented food) that has high functionality by subjecting a fructan-containing material (in particular, a material including garlic or rakkyo containing fructan at a high concentration) directly to lactic acid fermentation without performing a heat treatment or an enzymatic treatment. More specifically, provided are: a fermentation product having an immunopotentiating effect, which is obtained by lactic acid fermentation of a fructan-containing material using a lactic acid bacterium Lactobacillus plantarum S506 strain (NITE BP-643) having fructan-utilizing ability, a mutant strain of the S506 strain having fructan-utilizing ability, or a strain isolated from Lactobacillus plantarum and having the same bacteriological properties as those of the S506 strain; and a fermented food which contains the fermentation product.
摘要翻译： 通过在不进行热处理或酶处理的情况下，将含有果聚糖的材料（特别是含有高浓度的含有果聚糖的大蒜或rakkyo的材料）直接进行乳酸发酵而具有高功能性的发酵产品（发酵食品）。 更具体地说，提供：使用具有果聚糖利用能力的乳酸菌植物乳杆菌S506菌株（NITE BP-643），含有果聚糖的材料的乳酸发酵获得的具有免疫增强作用的发酵产物，突变体 具有果聚糖利用能力的S506菌株或从植物乳杆菌分离的菌株，具有与S506菌株相同的细菌学性质的菌株; 和含有发酵产物的发酵食品。
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4.发明授权公开(公告)号：US08647698B2
公开(公告)日：2014-02-11
申请号：US13201906
申请日：2010-02-15
IPC分类号： A23L1/212
CPC分类号： C12R1/25 , A23L27/24 , A23L33/105 , A61K36/8962 , C12N1/20 , A61K2300/00
摘要： A fermentation product (fermented food) that has high functionality by subjecting a fructan-containing material (in particular, a material including garlic or rakkyo containing fructan at a high concentration) directly to lactic acid fermentation without performing a heat treatment or an enzymatic treatment. More specifically, provided are: a fermentation product having an immunopotentiating effect, which is obtained by lactic acid fermentation of a fructan-containing material using a lactic acid bacterium Lactobacillus plantarum S506 strain (MITE BP-643) having fructan-utilizing ability, a mutant strain of the S506 strain having fructan-utilizing ability, or a strain isolated from Lactobacillus plantarum and having the same bacteriological properties as those of the S506 strain; and a fermented food which contains the fermentation product.
摘要翻译： 通过在不进行热处理或酶处理的情况下，将含有果聚糖的材料（特别是含有高浓度的含有果聚糖的大蒜或rakkyo的材料）直接进行乳酸发酵而具有高功能性的发酵产品（发酵食品）。 更具体地说，提供了具有免疫增强作用的发酵产物，其通过使用具有果聚糖利用能力的乳酸菌植物乳杆菌S506菌株（MITE BP-643）的乳酸发酵法获得，突变体 具有果聚糖利用能力的S506菌株或从植物乳杆菌分离的菌株，具有与S506菌株相同的细菌学性质的菌株; 和含有发酵产物的发酵食品。
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5.发明申请PROCESS FOR PRODUCTION OF ORALLY INGESTIBLE COMPOSITION CONTAINING ARABINOFURANOSYL VITEXIN, AND USE OF THE COMPOSITION 审中-公开生产含有阿拉伯呋喃维生素的异味不挥发成份的方法，以及组合物的使用公开(公告)号：US20120004193A1
公开(公告)日：2012-01-05
申请号：US13256805
申请日：2010-03-08
申请人： Shuichi Kusano
发明人： Shuichi Kusano
IPC分类号： A61K31/7048 , C07H1/08 , A61P25/20 , C07H7/06
CPC分类号： C07H17/04 , A23L2/52 , A23L33/105 , A61K31/353 , A61K31/7048 , A61K36/185 , C07D407/04
摘要： A method for producing an orally ingestible composition containing an arabinofuranosyl vitexin and/or a hydrolysate thereof by using Basella alba as a raw material. The product of such method has a sedative effect and a sleep-inducing effect.
摘要翻译： 一种通过使用巴西拉钡作为原料生产含有阿拉伯呋喃糖果黄素和/或其水解产物的口服摄取组合物的方法。 这种方法的产物具有镇静作用和睡眠诱导作用。
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