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公开(公告)号：US10285596B2
公开(公告)日：2019-05-14
申请号：US15485070
申请日：2017-04-11
申请人： Alfred Akerman , Stephen W. Allison , Matthew B. Scudiere , Michael R. Cates , David L. Beshears , Lara Brewer , Adan James Akerman
发明人： Alfred Akerman , Stephen W. Allison , Matthew B. Scudiere , Michael R. Cates , David L. Beshears , Lara Brewer , Adan James Akerman
摘要： A system for measuring the blood loss comprises a measuring device that determines a hemoglobin concentration of fluid within a container utilizing a light source and a light detector. The container receives blood and other fluids from a patient during a medical procedure. Light from the light source is passed through the blood and other fluids in the container and is detected by the light detector. Based upon a magnitude of light detected, a hemoglobin concentration of the fluid in the container can be determined. A volume-measuring device determines the volume of blood and fluid in the container. Knowing the hemoglobin concentration and volume of fluid in the container, the volume of patient blood loss in the container can be determined. The blood loss measuring device in combination with infusion systems maintains a real-blood volume status so that proper infusion of blood, crystalloid and/or colloid solutions occurs.
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公开(公告)号：US20170290518A1
公开(公告)日：2017-10-12
申请号：US15485070
申请日：2017-04-11
申请人： Alfred Akerman , Stephen W. Allison , Matthew B. Scudiere , Michael R. Cates , David L. Beshears , Lara Brewer , Adan James Akerman
发明人： Alfred Akerman , Stephen W. Allison , Matthew B. Scudiere , Michael R. Cates , David L. Beshears , Lara Brewer , Adan James Akerman
CPC分类号： A61B5/02042 , G01N21/314 , G01N21/3151 , G01N21/8507 , G01N33/49 , G01N2021/3181 , G01N2021/8528
摘要： A system for measuring the blood loss comprises a measuring device that determines a hemoglobin concentration of fluid within a container utilizing a light source and a light detector. The container receives blood and other fluids from a patient during a medical procedure. Light from the light source is passed through the blood and other fluids in the container and is detected by the light detector. Based upon a magnitude of light detected, a hemoglobin concentration of the fluid in the container can be determined. A volume-measuring device determines the volume of blood and fluid in the container. Knowing the hemoglobin concentration and volume of fluid in the container, the volume of patient blood loss in the container can be determined. The blood loss measuring device in combination with infusion systems maintains a real-blood volume status so that proper infusion of blood, crystalloid and/or colloid solutions occurs.
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3.发明授权Optical fiber sensors for monitoring joint articulation and chest expansion of a human body 失效用于监测人体关节关节和胸部扩张的光纤传感器
公开(公告)号：US5701370A
公开(公告)日：1997-12-23
申请号：US767697
申请日：1996-12-17
CPC分类号： G01B11/18
摘要： Fiber-optic sensors employing optical fibers of elastomeric material are incorporated in devices adapted to be worn by human beings in joint and chest regions for the purpose of monitoring and measuring the extent of joint articulation and chest expansion especially with respect to time.
摘要翻译： 使用采用弹性体材料的光纤的光纤传感器被并入适合人类在关节和胸部区域佩戴的装置中，目的是监测和测量关节和胸部扩张的程度，特别是在时间上。
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公开(公告)号：US5914785A
公开(公告)日：1999-06-22
申请号：US18502
申请日：1998-02-04
CPC分类号： G01S17/32 , G01B11/026
摘要： This invention relates to a method and apparatus for making absolute distance or ranging measurements using Fresnel diffraction. The invention employs a source of electromagnetic radiation having a known wavelength or wavelength distribution, which sends a beam of electromagnetic radiation through an object which causes it to be split (hereinafter referred to as a "beamsplitter"), and then to a target. The beam is reflected from the target onto a screen containing an aperture spaced a known distance from the beamsplitter. The aperture is sized so as to produce a Fresnel diffraction pattern. A portion of the beam travels through the aperture to a detector, spaced a known distance from the screen. The detector detects the central intensity of the beam. The distance from the object which causes the beam to be split to the target can then be calculated based upon the known wavelength, aperture radius, beam intensity, and distance from the detector to the screen. Several apparatus embodiments are disclosed for practicing the method embodiments of the present invention.
摘要翻译： 本发明涉及使用菲涅尔衍射进行绝对距离或测距测量的方法和装置。 本发明采用具有已知波长或波长分布的电磁辐射源，其通过使其分裂的物体（以下称为“分束器”）发送电磁辐射束，然后发送到目标。 光束从目标物反射到包含与分束器间隔已知距离的光圈的屏幕上。 孔径的大小可以产生菲涅尔衍射图。 光束的一部分穿过孔径到与屏幕隔开已知距离的检测器。 检测器检测光束的中心强度。 然后可以基于已知的波长，孔径半径，光束强度以及从检测器到屏幕的距离来计算使被分离到目标物体的物体的距离。 公开了用于实施本发明的方法实施例的几个装置实施例。
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公开(公告)号：US08406837B2
公开(公告)日：2013-03-26
申请号：US12513258
申请日：2007-11-01
申请人： George T. Gillies , Helen Fillmore , William C. Broaddus , Boyd M. Evans, III , Stephen W. Allison
发明人： George T. Gillies , Helen Fillmore , William C. Broaddus , Boyd M. Evans, III , Stephen W. Allison
IPC分类号： A61B5/00
CPC分类号： A61B5/0084 , A61B5/0071 , A61B5/0075
摘要： A functionalized tip is incorporated into catheters for the cytometric delivery of cells into the brain and other body parts. For use in the brain, the tip forms part of a neurosurgical probe having a proximal end and a distal end. In addition to the functionalized tip, the probe has at least one cell slurry delivery lumen and a plurality of optical fibers configured along the probe, terminating in the tip to provide the photo-optical capability needed to monitor the viability and physiological behavior of the grafted cells as well as certain characteristics of the cellular environment. Details are also presented of the use of a neurocatheter having a cytometric tip of the type disclosed in the invention, as employed within the context of a feedback and control system for regulating the number of cells delivered to the brain of a patient.
摘要翻译： 一个功能化的尖端被并入到导管中，用于将细胞细胞传递到脑和其他身体部位。 为了在脑中使用，尖端形成具有近端和远端的神经外科探针的一部分。 除了功能化的尖端之外，探针具有至少一个细胞浆液递送腔和沿着探针配置的多个光纤，终止于尖端，以提供监测嫁接的生存力和生理行为所需的光学光学能力 细胞以及细胞环境的某些特征。 还提供了在用于调节递送到患者脑部的细胞数量的反馈和控制系统的上下文中使用的具有本发明公开的类型的细胞计数尖端的神经导管的用途的细节。
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公开(公告)号：US20100210927A1
公开(公告)日：2010-08-19
申请号：US12513258
申请日：2007-11-01
CPC分类号： A61B5/0084 , A61B5/0071 , A61B5/0075
摘要： A functionalized tip is incorporated into catheters for the cytometric delivery of cells into the brain and other body parts. For use in the brain, the tip forms part of a neurosurgical probe having a proximal end and a distal end. In addition to the functionalized tip, the probe has at least one cell slurry delivery lumen and a plurality of optical fibers configured along the probe, terminating in the tip to provide the photo-optical capability needed to monitor the viability and physiological behavior of the grafted cells as well as certain characteristics of the cellular environment. Details are also presented of the use of a neurocatheter having a cytometric tip of the type disclosed in the invention, as employed within the context of a feedback and control system for regulating the number of cells delivered to the brain of a patient.
摘要翻译： 一个功能化的尖端被并入到导管中，用于将细胞细胞传递到脑和其他身体部位。 为了在脑中使用，尖端形成具有近端和远端的神经外科探针的一部分。 除了功能化的尖端之外，探针具有至少一个细胞浆液递送腔和沿着探针配置的多个光纤，终止于尖端，以提供监测嫁接的生存力和生理行为所需的光学光学能力 细胞以及细胞环境的某些特征。 还提供了在用于调节递送到患者脑部的细胞数量的反馈和控制系统的上下文中使用的具有本发明公开的类型的细胞计数尖端的神经导管的用途的细节。
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公开(公告)号：US06456383B1
公开(公告)日：2002-09-24
申请号：US09705847
申请日：2000-11-03
IPC分类号： G01D1114
CPC分类号： G01S17/32 , G01B11/026
摘要： This invention relates to a method and apparatus for making absolute distance or ranging measurements using Fresnel diffraction. The invention employs a source of electromagnetic radiation having a known wavelength or wavelength distribution, which sends a beam of electromagnetic radiation through a screen at least partially opaque at the wavelength. The screen has an aperture sized so as to produce a Fresnel diffraction pattern. A portion of the beam travels through the aperture to a detector spaced some distance from the screen. The detector detects the central intensity of the beam as well as a set of intensities displaced from a center of the aperture. The distance from the source to the target can then be calculated based upon the known wavelength, aperture radius, and beam intensity.
摘要翻译： 本发明涉及使用菲涅尔衍射进行绝对距离或测距测量的方法和装置。 本发明使用具有已知波长或波长分布的电磁辐射源，其将波长的电磁辐射通过至少部分不透明的波长的屏幕发射。 屏幕具有孔径，以便产生菲涅尔衍射图案。 光束的一部分穿过孔径到与屏幕隔开一定距离的检测器。 检测器检测光束的中心强度以及从孔径中心偏移的一组强度。 然后可以基于已知的波长，孔径半径和光束强度来计算从源到目标的距离。
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公开(公告)号：US5812729A
公开(公告)日：1998-09-22
申请号：US505422
申请日：1995-07-21
CPC分类号： G02B6/02 , G02B6/4206
摘要： A new light-transmitting device using a SCIN glass core and a novel calcium sodium cladding has been developed. The very high index of refraction, radiation hardness, similar solubility for rare earths and similar melt and viscosity characteristics of core and cladding materials makes them attractive for several applications such as high-numerical-aperture optical fibers and specialty lenses. Optical fibers up to 60 m in length have been drawn, and several simple lenses have been designed, ground, and polished. Preliminary results on the ability to directly cast optical components of lead-indium phosphate glass are also discussed as well as the suitability of these glasses as a host medium for rare-earth ion lasers and amplifiers.
摘要翻译： 已经开发了使用SCIN玻璃芯和新型钙钠包层的新的透光装置。 折射率，辐射硬度，稀土类似的溶解度和类似的芯材和包层材料的熔融和粘度特性使其具有很高的吸引力，可用于高数值孔径光纤和特种透镜等多种应用。 长达60米的光纤已经被绘制出来，几个简单的镜头被设计，研磨和抛光。 还讨论了直接投射磷酸铟铟玻璃的光学部件的能力的初步结果以及这些玻璃作为稀土离子激光器和放大器的主体介质的适用性。
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公开(公告)号：US07446860B1
公开(公告)日：2008-11-04
申请号：US11527648
申请日：2006-09-18
申请人： Jonathan W. Campbell , David L. Lehner , Larry L. Smalley , Molly C. Smith, legal representative , Alvin J. Sanders , Dennis Duncan Earl , Stephen W. Allison
发明人： Kelly L. Smith
IPC分类号： G01C3/08
摘要： A method and system for determining range to a target are provided. A beam of electromagnetic energy is transmitted through an aperture in an opaque screen such that a portion of the beam passes through the aperture to generate a region of diffraction that varies as a function of distance from the aperture. An imaging system is focused on a target plane in the region of diffraction with the generated image being compared to known diffraction patterns. Each known diffraction pattern has a unique value associated therewith that is indicative of a distance from the aperture. A match between the generated image and at least one of the known diffraction patterns is indicative of a distance between the aperture and target plane.
摘要翻译： 提供了一种用于确定目标范围的方法和系统。 电磁能束通过不透明屏幕中的孔传输，使得光束的一部分通过孔径，以产生随距孔径的函数而变化的衍射区域。 将成像系统聚焦在衍射区域中的目标平面上，将生成的图像与已知的衍射图案进行比较。 每个已知的衍射图案具有与其相关联的指示距离孔的距离的唯一值。 生成的图像与至少一个已知衍射图案之间的匹配表示孔径和目标平面之间的距离。
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公开(公告)号：US5885484A
公开(公告)日：1999-03-23
申请号：US933916
申请日：1997-09-23
CPC分类号： G01K11/20
摘要： A high temperature phosphor consists essentially of a material having the general formula LuPO.sub.4 :Dy.sub.(x),Eu.sub.y) wherein: 0.1 wt %.ltoreq.x.ltoreq.20 wt % and 0.1 wt %.ltoreq.y.ltoreq.20 wt %.The high temperature phosphor is in contact with an article whose temperature is to be determined. The article having the phosphor in contact with it is placed in the environment for which the temperature of the article is to be determined. The phosphor is excited by a laser causing the phosphor to fluoresce. The emission from the phosphor is optically focused into a beam-splitting mirror which separates the emission into two separate emissions, the emission caused by the dysprosium dopant and the emission caused by the europium dopent. The separated emissions are optically filtered and the intensities of the emission are detected and measured. The ratio of the intensity of each emission is determined and the temperature of the article is calculated from the ratio of the intensities of the separate emissions.
摘要翻译： 高温荧光体基本上由具有通式LuPO 4：Dy（x），Eu y）的材料组成，其中：0.1重量％≤20重量％，0.1重量％≤20重量％ ％。 高温荧光体与要测定其温度的物品接触。 具有与其接触的荧光体的物品被放置在要确定制品的温度的环境中。 磷光体被激光激发，导致磷光体发荧光。 来自磷光体的发射被光学聚焦成分束镜，其将发射分离成两个单独的发射，由镝掺杂物引起的发射和由铕掺杂引起的发射。 分离的发射被光学滤波，并且检测和测量发射的强度。 确定每个排放强度的比例，并根据单独排放强度的比率计算物品的温度。
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