公开(公告)号：US20120162607A1

公开(公告)日：2012-06-28

申请号：US13340998

申请日：2011-12-30

Applicant: Sverker Norrby

Inventor： Sverker Norrby

IPC: A61B3/00 ,  G06G7/60

CPC classification number: A61F2/1613 ,  A61B3/0025 ,  A61F2240/002

Abstract: The invention relates to devices and methods for selecting IOLs for implantation and eye models useful with the methods. One method comprises the steps of determining the axial eye length, the pupil size at a desired light level; the desired postoperative refraction; determining an aspheric representation of the corneal curvature and determining the location of the plane of fixation of the IOL following implantation.

Abstract translation: 本发明涉及用于选择用于植入的IOL和用于该方法的眼模型的装置和方法。 一种方法包括以下步骤：确定轴向眼睛长度，在期望的光水平下的瞳孔尺寸; 所需的术后折射; 确定角膜曲率的非球面表示并确定植入后IOL的固定平面的位置。

公开(公告)号：US20120059463A1

公开(公告)日：2012-03-08

申请号：US13222944

申请日：2011-08-31

Applicant: Sverker Norrby ,  Pablo Artal ,  Patricia Ann Piers ,  Marrie Van Der Mooren

Inventor： Sverker Norrby ,  Pablo Artal ,  Patricia Ann Piers ,  Marrie Van Der Mooren

IPC: A61F2/16

CPC classification number: A61B3/0025 ,  A61B3/1005 ,  A61B3/1015 ,  A61B3/1035 ,  A61B3/107 ,  A61F2/1613 ,  A61F2/1637 ,  A61F2/164 ,  A61F2240/002 ,  G02C7/028

Abstract: The present invention discloses methods of obtaining ophthalmic lens capable of reducing the aberrations of the eye comprising the steps of characterizing at least one corneal surface as a mathematical model, calculating the resulting aberrations of said corneal surface(s) by employing said mathematical model, selecting the optical power of the intraocular lens. From this information, an ophthalmic lens is modeled so a wavefront arriving from an optical system comprising said lens and corneal model obtains reduced aberrations in the eye. Also disclosed are ophthalmic lenses as obtained by the methods which are capable reducing aberrations of the eye.

Abstract translation: 本发明公开了获得能够减少眼睛像差的眼镜的方法，包括以下步骤：将至少一个角膜表面表征为数学模型，通过使用所述数学模型计算所得到的所述角膜表面的像差，选择 眼内透镜的光学功率。 根据该信息，对眼科镜进行建模，使得从包括所述透镜和角膜模型的光学系统到达的波前获得眼睛中的减少的像差。 还公开了通过能够减少眼睛畸变的方法获得的眼科镜片。

公开(公告)号：US20110128502A1

公开(公告)日：2011-06-02

申请号：US13021498

申请日：2011-02-04

Applicant: Sverker Norrby ,  Rolf Bergman

Inventor： Sverker Norrby ,  Rolf Bergman

IPC: A61B3/10

CPC classification number: A61F2/1613 ,  A61B3/0025 ,  A61B3/103 ,  A61B3/107

Abstract: A system for providing an intraocular lens includes a processor and a computer readable memory. The computer readable memory is configured to communicate with the processor, the memory having stored therein at least one of: one or more ocular dimensions, and at least one predetermined refractive outcome. The memory further includes a sequence of instructions which, when executed by the processor, cause the processor to select an intraocular lens, select a power of an intraocular lens, or provide an intraocular lens. The sequence of instructions includes determining one or more dimensions of an eye. The instructions also include calculating, based on a mathematical relationship, a distance from an apex of a cornea of the eye to an apex or plane of the intraocular lens after insertion into the eye. The instructions further calculating an optical power of the intraocular lens suitable for providing a predetermined refractive outcome. The mathematical relationship includes an axial length of the eye, an anterior chamber depth of the natural crystalline lens, and a corneal radius of the eye, but is independent of a thickness of the natural crystalline lens.

Abstract translation: 用于提供眼内透镜的系统包括处理器和计算机可读存储器。 计算机可读存储器被配置为与处理器通信，其中存储有存储器中的至少一个：一个或多个眼睛尺寸和至少一个预定折射结果。 所述存储器还包括指令序列，当由所述处理器执行时，使所述处理器选择人工晶状体，选择人工晶状体的能量或提供眼内透镜。 指令序列包括确定眼睛的一个或多个维度。 说明书还包括基于数学关系计算在插入眼睛之后从眼睛的角膜的顶点到眼内透镜的顶点或平面的距离。 所述指令还计算适于提供预定屈光结果的眼内透镜的光焦度。 数学关系包括眼睛的轴向长度，天然晶状体的前房深度和眼睛的角膜半径，但是与天然晶状体的厚度无关。

公开(公告)号：US20110082542A1

公开(公告)日：2011-04-07

申请号：US12954347

申请日：2010-11-24

Applicant: Sverker Norrby ,  Pablo Artal ,  Patricia Ann Piers ,  Marrie Van Der Mooren

Inventor： Sverker Norrby ,  Pablo Artal ,  Patricia Ann Piers ,  Marrie Van Der Mooren

IPC: A61F2/16

CPC classification number: A61B3/0025 ,  A61B3/1005 ,  A61B3/1015 ,  A61B3/1035 ,  A61B3/107 ,  A61F2/1613 ,  A61F2/1637 ,  A61F2/164 ,  A61F2240/002 ,  G02C7/028

Abstract: The present invention discloses methods of obtaining ophthalmic lens capable of reducing the aberrations of the eye comprising the steps of characterizing at least one corneal surface as a mathematical model, calculating the resulting aberrations of said corneal surface(s) by employing said mathematical model, selecting the optical power of the intraocular lens. From this information, an ophthalmic lens is modeled so a wavefront arriving from an optical system comprising said lens and corneal model obtains reduced aberrations in the eye. Also disclosed are ophthalmic lenses as obtained by the methods which are capable reducing aberrations of the eye.

Abstract translation: 本发明公开了获得能够减少眼睛像差的眼镜的方法，包括以下步骤：将至少一个角膜表面表征为数学模型，通过使用所述数学模型计算所得到的所述角膜表面的像差，选择 眼内透镜的光学功率。 根据该信息，对眼科镜进行建模，使得从包括所述透镜和角膜模型的光学系统到达的波前获得眼睛中的减少的像差。 还公开了通过能够减少眼睛畸变的方法获得的眼科镜片。

公开(公告)号：US07811267B2

公开(公告)日：2010-10-12

申请号：US10438618

申请日：2003-05-15

Applicant: Sverker Norrby ,  Rolf Bergman ,  Jöns Hillborn

Inventor： Sverker Norrby ,  Rolf Bergman ,  Jöns Hillborn

IPC: A61M35/00

CPC classification number: A61F2/1616 ,  A61F9/00736 ,  A61L31/044 ,  A61L31/046 ,  C09J189/00

Abstract: A kit is provided, which comprises a) a collagen patch and b) an adhesive composition comprising (i) fibrin, fibrinogen or a combination thereof, and (ii) a biocompatible polymer capable of forming a viscous aqueous solution.Also provided is use of the kit for the preparation of a sealing device for use in ophthalmic surgery to replace a natural lens which has been removed, in which sealing device the collagen patch of the kit is adapted to seal an opening in a capsular bag of an eye while admitting the entrance of an injection device through the opening for injection of a lens-forming material into the capsule; and in which sealing device the adhesive composition of the kit is adapted to be applied to the collagen patch so as to enable adhesion of the collagen patch to the capsular bag.Also provided are methods for sealing an opening in a capsular bag of an eye, in which methods the kit is employed.

Abstract translation: 提供了一种试剂盒，其包括a）胶原蛋白片和b）包含（i）纤维蛋白，纤维蛋白原或其组合的粘合剂组合物，和（ii）能够形成粘性水溶液的生物相容性聚合物。 还提供了该套件的用途，用于制备用于眼科手术中的密封装置，以取代已经去除的天然晶状体，其中该成套件的胶原贴片的密封装置适于密封囊袋中的开口 眼睛同时通过用于将透镜形成材料注入胶囊的开口进入注射装置; 并且其中将所述试剂盒的粘合剂组合物适用于所述胶原蛋白贴片的密封装置，以便能够将所述胶原蛋白贴片粘附到所述胶囊袋上。 还提供了用于密封眼睛囊袋中的开口的方法，其中采用该试剂盒的方法。

公开(公告)号：US20070188700A1

公开(公告)日：2007-08-16

申请号：US11734238

申请日：2007-04-11

Applicant: Patricia Piers ,  Hendrik Weeber ,  Sverker Norrby

Inventor： Patricia Piers ,  Hendrik Weeber ,  Sverker Norrby

IPC: G02C7/04

CPC classification number: A61F2/1618 ,  A61B3/0025 ,  A61F2/1613 ,  A61F2/1616 ,  A61F2/1637 ,  A61F2/164 ,  A61F2/1654 ,  A61F2002/1681 ,  A61F2002/1696 ,  A61F2240/001 ,  A61F2240/002 ,  G01J9/00 ,  G02C7/028 ,  G02C7/041 ,  G02C7/042 ,  G02C7/044 ,  G02C7/06 ,  G02C2202/20 ,  G02C2202/22

Abstract: A method of designing a multifocal ophthalmic lens with one base focus and at least one additional focus, capable of reducing aberrations of the eye for at least one of the foci after its implantation, comprising the steps of: (i) characterizing at least one corneal surface as a mathematical model; (ii) calculating the resulting aberrations of said corneal surface(s) by employing said mathematical model; (iii) modeling the multifocal ophthalmic lens such that a wavefront arriving from an optical system comprising said lens and said at least one corneal surface obtains reduced aberrations for at least one of the foci. There is also disclosed a method of selecting a multifocal intraocular lens, a method of designing a multifocal ophthalmic lens based on corneal data from a group of patients, and a multifocal ophthalmic lens.

Abstract translation: 一种设计具有一个基底焦点和至少一个附加焦点的多焦点眼科镜片的方法，其能够在其植入之后减少至少一个焦点的眼睛的像差，包括以下步骤：（i）表征至少一个角膜 表面作为数学模型; （ii）通过使用所述数学模型来计算所得到的所述角膜表面的像差; （iii）对多焦点眼科镜片进行建模，使得从包括所述透镜和所述至少一个角膜表面的光学系统到达的波前获得至少一个焦点的减少的像差。 还公开了一种选择多焦点眼内透镜的方法，基于来自一组患者的角膜数据设计多焦点眼科镜片的方法和多焦点眼科镜片。

公开(公告)号：US20060244905A1

公开(公告)日：2006-11-02

申请号：US11426187

申请日：2006-06-23

Applicant: Patricia Piers ,  Hendrik Weeber ,  Sverker Norrby

Inventor： Patricia Piers ,  Hendrik Weeber ,  Sverker Norrby

IPC: G02C7/04

CPC classification number: A61F2/1618 ,  A61B3/0025 ,  A61F2/1613 ,  A61F2/1616 ,  A61F2/1637 ,  A61F2/164 ,  A61F2/1654 ,  A61F2002/1681 ,  A61F2002/1696 ,  A61F2240/001 ,  A61F2240/002 ,  G01J9/00 ,  G02C7/028 ,  G02C7/041 ,  G02C7/042 ,  G02C7/044 ,  G02C7/06 ,  G02C2202/20 ,  G02C2202/22

Abstract: A method of designing a multifocal ophthalmic lens with one base focus and at least one additional focus, capable of reducing aberrations of the eye for at least one of the foci after its implantation, comprising the steps of: (i) characterizing at least one corneal surface as a mathematical model; (ii) calculating the resulting aberrations of said corneal surface(s) by employing said mathematical model; (iii) modelling the multifocal ophthalmic lens such that a wavefront arriving from an optical system comprising said lens and said at least one corneal surface obtains reduced aberrations for at least one of the foci. There is also disclosed a method of selecting a multifocal intraocular lens, a method of designing a multifocal ophthalmic lens based on corneal data from a group of patients, and a multifocal ophthalmic lens.

公开(公告)号：US20060064163A1

公开(公告)日：2006-03-23

申请号：US11233295

申请日：2005-09-21

Applicant: Thom Terwee ,  Sverker Norrby ,  Robert Shimizu ,  Rolf Bergman

Inventor： Thom Terwee ,  Sverker Norrby ,  Robert Shimizu ,  Rolf Bergman

IPC: A61F2/16 ,  A61F2/02 ,  A61F9/013

CPC classification number: A61K9/0048 ,  A61L27/20 ,  A61L27/54 ,  A61L2300/416 ,  A61L2430/16 ,  C08L5/08

Abstract: The invention relates to method of preparing a viscoelastic therapeutic liquid comprising a viscoelastic agent and a homogenously distributed therapeutically active agent, wherein the therapeutically active agent is distributed throughout the viscoelastic compound when the viscoelastic compound is in dry form. In one embodiment of the invention, the viscoelastic compound in dry form is mixed with an aqueous solution of the therapeutically active agent. The invention further relates to utilities of homogenous viscoelastic compositions in therapeutic applications including ophthalmic surgery.

公开(公告)号：US08529623B2

公开(公告)日：2013-09-10

申请号：US13015702

申请日：2011-01-28

Applicant: Patricia Ann Piers ,  Hendrik Albert Weeber ,  Sverker Norrby

Inventor： Patricia Ann Piers ,  Hendrik Albert Weeber ,  Sverker Norrby

IPC: A61F2/16

CPC classification number: A61F2/1618 ,  A61B3/0025 ,  A61F2/1613 ,  A61F2/1616 ,  A61F2/1637 ,  A61F2/164 ,  A61F2/1654 ,  A61F2002/1681 ,  A61F2002/1696 ,  A61F2240/001 ,  A61F2240/002 ,  G01J9/00 ,  G02C7/028 ,  G02C7/041 ,  G02C7/042 ,  G02C7/044 ,  G02C7/06 ,  G02C2202/20 ,  G02C2202/22

Abstract: A method of designing a multifocal ophthalmic lens with one base focus and at least one additional focus, capable of reducing aberrations of the eye for at least one of the foci after its implantation, comprising the steps of: (i) characterizing at least one corneal surface as a mathematical model; (ii) calculating the resulting aberrations of said corneal surface(s) by employing said mathematical model; (iii) modelling the multifocal ophthalmic lens such that a wavefront arriving from an optical system comprising said lens and said at least one corneal surface obtains reduced aberrations for at least one of the foci. There is also disclosed a method of selecting a multifocal intraocular lens, a method of designing a multifocal ophthalmic lens based on corneal data from a group of patients, and a multifocal ophthalmic lens.

Abstract translation: 一种设计具有一个基底焦点和至少一个附加焦点的多焦点眼科镜片的方法，其能够在其植入之后减少至少一个焦点的眼睛的像差，包括以下步骤：（i）表征至少一个角膜 表面作为数学模型; （ii）通过使用所述数学模型来计算所得到的所述角膜表面的像差; （iii）对多焦点眼科镜片进行建模，使得从包括所述透镜和所述至少一个角膜表面的光学系统到达的波前获得至少一个焦点的减少的像差。 还公开了一种选择多焦点眼内透镜的方法，基于来自一组患者的角膜数据设计多焦点眼科镜片的方法和多焦点眼科镜片。

公开(公告)号：US07841720B2

公开(公告)日：2010-11-30

申请号：US12175395

申请日：2008-07-17

Applicant: Sverker Norrby ,  Pablo Artal ,  Patricia Ann Piers ,  Marrie Van Der Mooren

Inventor： Sverker Norrby ,  Pablo Artal ,  Patricia Ann Piers ,  Marrie Van Der Mooren

IPC: A61B3/10

CPC classification number: A61B3/0025 ,  A61F2/1637 ,  A61F2240/002 ,  G02C7/02 ,  G02C7/028 ,  G02C2202/06 ,  G02C2202/22

Abstract: The present invention discloses methods of obtaining ophthalmic lens capable of reducing the aberrations of the eye comprising the steps of characterizing at least one corneal surface as a mathematical model, calculating the resulting aberrations of said corneal surface(s) by employing said mathematical model, selecting the optical power of the intraocular lens. From this information, an ophthalmic lens is modeled so a wavefront arriving from an optical system comprising said lens and corneal model obtains reduced aberrations in the eye. Also disclosed are ophthalmic lenses as obtained by the methods which are capable reducing aberrations of the eye.

Abstract translation: 本发明公开了获得能够减少眼睛像差的眼镜的方法，包括以下步骤：将至少一个角膜表面表征为数学模型，通过使用所述数学模型计算所得到的所述角膜表面的像差，选择 眼内透镜的光学功率。 根据该信息，对眼科镜进行建模，使得从包括所述透镜和角膜模型的光学系统到达的波前获得眼睛中的减少的像差。 还公开了通过能够减少眼睛畸变的方法获得的眼科镜片。