公开(公告)号：USD1067314S1

公开(公告)日：2025-03-18

申请号：US29761621

申请日：2020-12-10

Applicant: JINS HOLDINGS Inc. ,  TSUBOTA LABORATORY, Inc.

Designer： Daisuke Kaneda

公开(公告)号：US20240033311A1

公开(公告)日：2024-02-01

申请号：US18483161

申请日：2023-10-09

Applicant: TSUBOTA LABORATORY, INC. ,  ROHTO PHARMACEUTICAL CO., LTD.

Inventor： Kazuo TSUBOTA ,  Toshihide KURIHARA

IPC: A61K36/16 ,  A61P27/10 ,  A61K9/00 ,  A61K31/05 ,  A61K31/202

CPC classification number: A61K36/16 ,  A61P27/10 ,  A61K9/0056 ,  A61K31/05 ,  A61K31/202

Abstract: The ophthalmic composition effective for the prevention or treatment of myopia or ocular diseases are provided. In particular, the present invention provides an ophthalmic composition effective in a growing child or a young person in whom myopia develops and progresses, as well as a middle-aged and elderly person in whom age-related ocular diseases such as cataract, glaucoma, retinal detachment, retinopathy, maculopathy, choroidal neovascularization, posterior staphyloma, and optic neuropathy develop, a functional food containing the ophthalmic composition, and a screening method capable of searching for the same. [Solution] The above problem is solved by an ophthalmic composition or functional food product containing at least one component selected from the group consisting of crocetin and its pharmaceutically acceptable salts and ginkgo leaf extract.

公开(公告)号：US20230218164A1

公开(公告)日：2023-07-13

申请号：US18000601

申请日：2022-03-10

Applicant: TSUBOTA LABORATORY, INC.

Inventor： Kazuo TSUBOTA ,  Hidenaga KOBASHI ,  Naoko KATO

IPC: A61B3/107 ,  A61B3/14

CPC classification number: A61B3/107 ,  A61B3/14 ,  A61B2560/06

Abstract: A simple diagnosis assisting device (10) for keratoconus and/or astigmatism, including a mobile terminal (10A) including a camera (2) and a transceiver function (3), and integrally or separately provided with a light source (1) for simultaneously projecting ring light onto both eyes. The light source (1) emits the ring light upon being attached to the mobile terminal (10A) in a case of being separately provided to the mobile terminal (10A), and emits the ring light from the mobile terminal (10A) in a case of being integrally provided to the mobile terminal (10A). The camera (2) simultaneously captures a projected image of both eyes onto which the ring light is projected. The ring light may be multiplex ring light or simplex ring light, and is configured in a ring shape by a plurality of point light sources or is configured in a ring shape by a single linear light source.

公开(公告)号：US20200171112A1

公开(公告)日：2020-06-04

申请号：US16614176

申请日：2018-05-15

Applicant: TSUBOTA LABORATORY, INC. ,  ROHTO PHARMACEUTICAL CO., LTD.

Inventor： Kazuo TSUBOTA ,  Toshihide KURIHARA

IPC: A61K36/16 ,  A61K31/202 ,  A61K31/05 ,  A61K9/00 ,  A61P27/10

Abstract: The ophthalmic composition effective for the prevention or treatment of myopia or ocular diseases are provided. In particular, the present invention provides an ophthalmic composition effective in a growing child or a young person in whom myopia develops and progresses, as well as a middle-aged and elderly person in whom age-related ocular diseases such as cataract, glaucoma, retinal detachment, retinopathy, maculopathy, choroidal neovascularization, posterior staphyloma, and optic neuropathy develop, a functional food containing the ophthalmic composition, and a screening method capable of searching for the same. [Solution] The above problem is solved by an ophthalmic composition or functional food product containing at least one component selected from the group consisting of crocetin and its pharmaceutically acceptable salts and ginkgo leaf extract.

公开(公告)号：US20200092971A1

公开(公告)日：2020-03-19

申请号：US16473487

申请日：2017-12-26

Applicant: TSUBOTA LABORATORY, INC.

Inventor： Kazuo TSUBOTA

IPC: H05B37/02 ,  G06F3/147

Abstract: To provide a display system such as a smartphone, a game console, a personal computer, or a liquid crystal television, including a light-emitting element that irradiates light having a specific wavelength toward a user. The above-described problem is solved by a display system (1) including a first light-emitting element (6) that emits light used for image display, a second light-emitting element (3) that irradiates light (7) within a wavelength range of 360 nm to 400 nm, inclusive, toward a user, and a control unit (10) that controls irradiation of the light (7) from the second light-emitting element (3). At this time, the second light-emitting element (3) may be a single light-emitting element integrated with the first light-emitting element (6) or a light-emitting element provided separately from the first light-emitting element (6). When separately provided from the first light-emitting element (6), the second light-emitting element (3) is preferably provided to a peripheral frame (4) of a display screen (2), in the display screen (2), or as an accessory (5).

公开(公告)号：US20180351050A1

公开(公告)日：2018-12-06

申请号：US16044909

申请日：2018-07-25

Applicant: TOSHIBA MATERIALS CO., LTD. ,  TSUBOTA LABORATORY, INC.

Inventor： Masahiko Yamakawa ,  Hidemasa Torii ,  Toshihide Kurihara ,  Kazuo Tsubota

IPC: H01L33/50 ,  H01L25/075 ,  C09K11/77

CPC classification number: A61F9/00 ,  A61N5/06 ,  F21S2/00 ,  F21V9/30 ,  H01L33/50

Abstract: A light source for myopia prevention article includes a light emitter to emit light having an emission spectrum continuing from a first wavelength of not less than 360 nm nor more than 400 nm to a second wavelength of more than 400 nm.

公开(公告)号：US20180341122A1

公开(公告)日：2018-11-29

申请号：US15778015

申请日：2015-11-25

Applicant: JINS INC. ,  Tsubota Laboratory, Inc.

Inventor： Shunsuke Shioya ,  Kazuo Tsubota ,  Toshihide Kurihara ,  Hidemasa Toril

IPC: G02C7/04 ,  G02B5/23 ,  G02C7/10 ,  G02C7/02

Abstract: An optical element has a transmission spectrum characterized in that a local maximum falls within a wavelength region longer than 315 nm but shorter than or equal to 400 nm, a local minimum falls within a wavelength region longer than or equal to 380 nm but shorter than or equal to 500 nm, and the wavelength at the local maximum is shorter than the wavelength at the local minimum.

公开(公告)号：US10133092B2

公开(公告)日：2018-11-20

申请号：US15366558

申请日：2016-12-01

Applicant: TSUBOTA LABORATORY, INC.

Inventor： Kazuo Tsubota ,  Kazuno Negishi ,  Hidemasa Torii ,  Toshihide Kurihara

IPC: G02C7/14 ,  G02C3/00 ,  G02C7/02 ,  G02C7/10 ,  F21V9/00 ,  G02C11/04

Abstract: The purpose of the present invention is to provide a myopia prevention device. A myopia prevention device of the present invention comprises a light transmission part selected from a group consisting of an eyesight correcting tool, an eye protection tool, a face protection tool, a sunshade, a display device, a window, a wall, a light source covering, and a coating material. The light transmission part of the device transmits light having a wavelength within a range of 350 nm to 400 nm inclusive and thus suppresses the occurrence and progression of myopia. Further, a myopia prevention device comprises a light emission part selected from a group consisting of lighting equipment, a display device, and a light irradiation device. The light emission part of the device emits light having a wavelength within a range of 350 nm to 400 nm inclusive and thus suppresses the occurrence and progression of myopia.

公开(公告)号：US20170168320A1

公开(公告)日：2017-06-15

申请号：US15366558

申请日：2016-12-01

Applicant: TSUBOTA LABORATORY, INC.

Inventor： Kazuo TSUBOTA ,  Kazuno NEGISHI ,  Hidemasa TORII ,  Toshihide KURIHARA

IPC: G02C7/10 ,  G02C11/04 ,  F21V9/00

CPC classification number: G02C7/104 ,  A61F2/16 ,  A61F9/00 ,  F21S2/00 ,  F21V9/00 ,  G02C7/00 ,  G02C7/02 ,  G02C7/04 ,  G02C11/04 ,  G02C2202/24

Abstract: The purpose of the present invention is to provide a myopia prevention device. A myopia prevention device of the present invention comprises a light transmission part selected from a group consisting of an eyesight correcting tool, an eye protection tool, a face protection tool, a sunshade, a display device, a window, a wall, a light source covering, and a coating material. The light transmission part of the device transmits light having a wavelength within a range of 350 nm to 400 nm inclusive and thus suppresses the occurrence and progression of myopia. Further, a myopia prevention device comprises a light emission part selected from a group consisting of lighting equipment, a display device, and a light irradiation device. The light emission part of the device emits light having a wavelength within a range of 350 nm to 400 nm inclusive and thus suppresses the occurrence and progression of myopia.

公开(公告)号：US20240398736A1

公开(公告)日：2024-12-05

申请号：US18266103

申请日：2021-09-01

Applicant: Tsubota Laboratory, Inc. ,  ROHTO PHARMACEUTICAL CO., LTD.

Inventor： Kazuo Tsubota ,  Toshihide Kurihara ,  Shinichi Ikeda ,  Kiwako Mori ,  Xiaoyan Jiang

IPC: A61K31/192 ,  A61P27/10 ,  G01N33/50

Abstract: The present invention provides a screening method for searching a component inhibiting or treating scleral thinning, and eyedrops that contain the active ingredient, and hence can inhibit excessive thinning of the sclera, and as a result, can treat a posterior segment eye disease associated with the scleral thinning. The problems are solved by eyedrops containing, as an active ingredient, a component capable of simultaneously inhibiting the PERK pathway and/or the ATF6 pathway. The problems are solved by a screening method for a component capable of simultaneously inhibiting the PERK pathway and/or the ATF6 pathway, including a step of contacting a candidate substance with an eye-derived cell, and a step of selecting the candidate substance using, as an indicator, influence on scleral thinning in the cell.