公开(公告)号：US20070054327A1

公开(公告)日：2007-03-08

申请号：US10572801

申请日：2004-11-19

申请人： Takafumi Iseri ,  Teruaki Miyamura ,  Junji Matsuda ,  Shiro Kanegasaki

发明人： Takafumi Iseri ,  Teruaki Miyamura ,  Junji Matsuda ,  Shiro Kanegasaki

IPC分类号： G01N33/567

CPC分类号： G02B21/34 ,  B01L3/5027 ,  C12M41/36

摘要： There is provided cell observation apparatus (10) comprising cell observation chamber (30) and optical observation means (70), the cell observation chamber (30) having, disposed thereinside, a pair of wells and a channel through which the wells communicate with each other so that cells of a cell suspension stocked in one of the pair of wells can react with a chemotaxis-factor-containing solution stocked in the other well and can move from the one well to the other well through the channel, the optical observation means (70) capable of optically observing the cells moving through the channel from outside of the cell observation chamber (30), wherein the cell observation chamber (30) with its part exposed from casing (20) is housed in the casing (20) and wherein the optical observation means (70) is housed in the casing (20) so that the optical axis thereof horizontally extends alow in the cell observation chamber (30). Thus, there can be obtained a cell observation apparatus that is compact, being easy in transfer and that has strikingly been improved with respect to handleability.

摘要翻译： 提供了包括细胞观察室（30）和光学观察装置（70）的细胞观察装置（10），细胞观察室（30）在其旁边设置有一对孔和孔，孔与孔连通 存储在一对孔中的一个孔中的细胞悬浮液的细胞可以与储存在另一孔中的含有趋化因子的溶液反应，并且可以通过通道从一个孔移动到另一个孔，光学观察装置 （70），其能够从所述电池观察室（30）的外部光学地观察从所述通道移动的电池，其中，从所述壳体（20）露出的部分的电池观察室（30）容纳在所述壳体（20）内， 其中光学观察装置（70）容纳在壳体（20）中，使得其光轴在电池观察室（30）中水平地延伸。 因此，可以获得紧凑，易于转移并相对于可操作性显着提高的细胞观察装置。

公开(公告)号：US08568660B2

公开(公告)日：2013-10-29

申请号：US11448878

申请日：2006-06-08

申请人： Shiro Kanegasaki ,  Takafumi Iseri

发明人： Shiro Kanegasaki ,  Takafumi Iseri

IPC分类号： G01N21/00

CPC分类号： C12M41/36 ,  G01N15/0612 ,  G01N35/00069 ,  G01N2015/0065 ,  G01N2015/144 ,  G01N2015/1486

摘要： A disk for storing liquid samples containing cells and for use in counting and observing the cells through an optical microscope includes an upper member formed of a transparent material and having a plurality of liquid inlets arranged radially and adapted to introduce the corresponding liquid samples therethrough, and a plurality of air vents paired with the corresponding liquid inlets; an intermediate member having a plurality of chambers arranged radially and adapted to store the corresponding liquid samples therein, each chamber corresponding to each pair of the liquid inlet and the air vent and communicating with the liquid inlet and with the air vent; and a lower member formed of a transparent material and backing the intermediate member. The optical microscope assumes the form of an incident-light microscope.

摘要翻译： 用于存储含有细胞并用于通过光学显微镜计数和观察细胞的液体样品的盘包括由透明材料形成的上部构件，并且具有径向布置的多个液体入口并适于将相应的液体样品通过其引入， 多个通风口与相应的液体入口配对; 中间构件，其具有径向布置并适于在其中存储相应的液体样本的多个室，每个室对应于每对液体入口和排气口，并与液体入口和排气口连通; 以及由透明材料形成并支撑中间构件的下部构件。 光学显微镜采用入射光显微镜的形式。

公开(公告)号：US07550114B2

公开(公告)日：2009-06-23

申请号：US10572801

申请日：2004-11-19

申请人： Takafumi Iseri ,  Teruaki Miyamura ,  Junji Matsuda ,  Shiro Kanegasaki

发明人： Takafumi Iseri ,  Teruaki Miyamura ,  Junji Matsuda ,  Shiro Kanegasaki

IPC分类号： G01N21/00

CPC分类号： G02B21/34 ,  B01L3/5027 ,  C12M41/36

摘要： There is provided cell observation apparatus (10) comprising cell observation chamber (30) and optical observation means (70), the cell observation chamber (30) having, disposed thereinside, a pair of wells and a channel through which the wells communicate with each other so that cells of a cell suspension stocked in one of the pair of wells can react with a chemotaxis-factor-containing solution stocked in the other well and can move from the one well to the other well through the channel, the optical observation means (70) capable of optically observing the cells moving through the channel from outside of the cell observation chamber (30), wherein the cell observation chamber (30) with its part exposed from casing (20) is housed in the casing (20) and wherein the optical observation means (70) is housed in the casing (20) so that the optical axis thereof horizontally extends allow in the cell observation chamber (30). Thus, there can be obtained a cell observation apparatus that is compact, being easy in transfer and that has strikingly been improved with respect to handleability.

摘要翻译： 提供了包括细胞观察室（30）和光学观察装置（70）的细胞观察装置（10），细胞观察室（30）在其旁边设置有一对孔和孔，孔与孔连通 存储在一对孔中的一个孔中的细胞悬浮液的细胞可以与储存在另一孔中的含有趋化因子的溶液反应，并且可以通过通道从一个孔移动到另一个孔，光学观察装置 （70），其能够从所述电池观察室（30）的外部光学地观察从所述通道移动的电池，其中，从所述壳体（20）露出的部分的电池观察室（30）容纳在所述壳体（20）内， 其中所述光学观察装置（70）容纳在所述壳体（20）中，使得其光轴在所述细胞观察室（30）中水平延伸。 因此，可以获得紧凑，易于转移并相对于可操作性显着提高的细胞观察装置。

公开(公告)号：US20100097605A1

公开(公告)日：2010-04-22

申请号：US12445350

申请日：2007-10-19

申请人： Seigo Murakami ,  Takenori Hirakawa ,  Takafumi Iseri

发明人： Seigo Murakami ,  Takenori Hirakawa ,  Takafumi Iseri

IPC分类号： G01N15/02

CPC分类号： B01D65/102 ,  B01D61/20 ,  B01D2311/06 ,  B01D2311/24 ,  C02F1/008 ,  C02F1/44 ,  C02F2209/005 ,  C02F2209/11 ,  G01N15/0227 ,  G01N2015/0693

摘要： A filtrate monitoring device and a filtrate monitoring system, which can monitor a membrane-type water filtrating/purifying system at all times and which can flexibly adjust themselves to the contents and sizes of impurities, are provided. The filtrate monitoring device monitors the filtrate having passed through the membrane-type water filtrating/purifying device. The filtrate monitoring device comprises: imaging/detecting means for shooting images in the filtrate having passed through the filtrating/purifying device, on the filtrate flowing in an observation bath of a filtrate observing cell disposed midway of the branched filtrate pipeline, thereby to specify the particles contained in the filtrate, and/or optical detecting means disposed midway of the filtrate pipeline before or after branching.

摘要翻译： 提供滤液监测装置和滤液监测系统，其可以一直监测膜式水过滤/净化系统，并且可以灵活地调节其杂质的含量和尺寸。 滤液监测装置监测通过膜式水过滤净化装置的滤液。 滤液检测装置包括：在通过过滤净化装置的滤液中拍摄图像的滤液检测装置，在设置在分支滤液管线中途的滤液观察池的观察池中流动的滤液上， 包含在滤液中的颗粒和/或在分支之前或之后设置在滤液管线中间的光学检测装置。

公开(公告)号：US20070063142A1

公开(公告)日：2007-03-22

申请号：US11448878

申请日：2006-06-08

申请人： Shiro Kanegasaki ,  Takafumi Iseri

发明人： Shiro Kanegasaki ,  Takafumi Iseri

IPC分类号： G01N23/00

CPC分类号： C12M41/36 ,  G01N15/0612 ,  G01N35/00069 ,  G01N2015/0065 ,  G01N2015/144 ,  G01N2015/1486

摘要： A disk for storing liquid samples containing cells and for use in counting and observing the cells through an optical microscope includes an upper member formed of a transparent material and having a plurality of liquid inlets arranged radially and adapted to introduce the corresponding liquid samples therethrough, and a plurality of air vents paired with the corresponding liquid inlets; an intermediate member having a plurality of chambers arranged radially and adapted to store the corresponding liquid samples therein, each chamber corresponding to each pair of the liquid inlet and the air vent and communicating with the liquid inlet and with the air vent; and a lower member formed of a transparent material and backing the intermediate member. The optical microscope assumes the form of an incident-light microscope.

摘要翻译： 用于存储含有细胞并用于通过光学显微镜计数和观察细胞的液体样品的盘包括由透明材料形成的上部构件，并且具有径向布置的多个液体入口并适于将相应的液体样品通过其引入， 多个通风口与相应的液体入口配对; 中间构件，其具有径向布置并适于在其中存储相应的液体样本的多个室，每个室对应于每对液体入口和排气口，并与液体入口和排气口连通; 以及由透明材料形成并支撑中间构件的下部构件。 光学显微镜采用入射光显微镜的形式。

公开(公告)号：US06702099B2

公开(公告)日：2004-03-09

申请号：US10225438

申请日：2002-08-22

申请人： Tetsunori Otaguro ,  Kazuyuki Matsumura ,  Takafumi Iseri

发明人： Tetsunori Otaguro ,  Kazuyuki Matsumura ,  Takafumi Iseri

IPC分类号： B65G4734

CPC分类号： H01L21/67706 ,  H01L21/67727 ,  H01L21/6773 ,  H01L21/67733 ,  H01L21/67736

摘要： A work conveying system eliminates gravitational deflection of an extended articulated arm of a vertical mover. The conveying system includes a horizontal mover which carries the vertical mover and a work holder for delivering a workpiece to various apparatuses without dislocation. In conveying a workpiece horizontally, the vertical mover folds compactly to minimize air disturbance. Plural arm elements of the articulated arm overlap and are connected together in an alternate manner at their respective end portions, and the articulated arm is extended and contracted by pivotal movement of the arm elements, driven by a single drive unit. The horizontal mover is movable in an arbitrary horizontal plane within the upper ceiling space within the clean room. Shafts in the articulated arm and a rotary drive unit in the work holder have hollow interiors which are intercommunicated and at a negative pressure.

摘要翻译： 工作输送系统消除了垂直移动器的延伸关节臂的重力偏转。 输送系统包括一个水平移动器，其承载垂直移动器和一个工件保持器，用于将工件传送到各种设备而不脱位。 在水平传送工件时，垂直移动器紧凑地折叠以最小化空气扰动。 铰接臂的多个臂元件在其各自的端部处以交替的方式重叠并且连接在一起，并且铰接臂通过由单个驱动单元驱动的臂元件的枢转运动而伸展和收缩。 水平移动器可在洁净室内的上部天花板空间内的任意水平面上移动。 铰接臂中的轴和工作架中的旋转驱动单元具有相互通信并处于负压的中空内部。

公开(公告)号：US08142660B2

公开(公告)日：2012-03-27

申请号：US12445350

申请日：2007-10-19

申请人： Seigo Murakami ,  Takenori Hirakawa ,  Takafumi Iseri

发明人： Seigo Murakami ,  Takenori Hirakawa ,  Takafumi Iseri

IPC分类号： B01D35/00 ,  C02F1/44

CPC分类号： B01D65/102 ,  B01D61/20 ,  B01D2311/06 ,  B01D2311/24 ,  C02F1/008 ,  C02F1/44 ,  C02F2209/005 ,  C02F2209/11 ,  G01N15/0227 ,  G01N2015/0693

摘要： A filtrate monitoring device and a filtrate monitoring system, which can monitor a membrane-type water filtrating/purifying system at all times and which can flexibly adjust themselves to the contents and sizes of impurities, are provided. The filtrate monitoring device monitors the filtrate having passed through the membrane-type water filtrating/purifying device. The filtrate monitoring device comprises: imaging/detecting means for shooting images in the filtrate having passed through the filtrating/purifying device, on the filtrate flowing in an observation bath of a filtrate observing cell disposed midway of the branched filtrate pipeline, thereby to specify the particles contained in the filtrate, and/or optical detecting means disposed midway of the filtrate pipeline before or after branching.

摘要翻译： 提供滤液监测装置和滤液监测系统，其可以一直监测膜式水过滤/净化系统，并且可以灵活地调节其杂质的含量和尺寸。 滤液监测装置监测通过膜式水过滤净化装置的滤液。 滤液检测装置包括：在通过过滤净化装置的滤液中拍摄图像的滤液检测装置，在设置在分支滤液管线中途的滤液观察池的观察池中流动的滤液上， 包含在滤液中的颗粒和/或在分支之前或之后设置在滤液管线中间的光学检测装置。