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公开(公告)号:US20100248359A1
公开(公告)日:2010-09-30
申请号:US12797349
申请日:2010-06-09
申请人: Kiyotaka Nakano , Takeshi Yoshino , Jun-Ichi Nezu , Hiroyuki Tsunoda , Tomoyuki Igawa , Hiroko Konishi , Megumi Tanaka , Izumi Sugo , Shigeto Kawai , Takahiro Ishiguro , Yasuko Kinoshita
发明人: Kiyotaka Nakano , Takeshi Yoshino , Jun-Ichi Nezu , Hiroyuki Tsunoda , Tomoyuki Igawa , Hiroko Konishi , Megumi Tanaka , Izumi Sugo , Shigeto Kawai , Takahiro Ishiguro , Yasuko Kinoshita
CPC分类号: C07K16/28 , C07K7/06 , C07K14/47 , C07K16/303 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/732 , C07K2317/734 , C07K2317/92
摘要: An antibody capable of binding to a specific region of glypican 3, as well as a humanized antibody created based on that antibody are disclosed. The anti-GPC3 antibody of the invention has a higher ADCC activity and CDC activity compared with those of a conventional antibody. The antibody of the present invention is useful as a cell growth inhibitor, an anticancer agent and an agent for diagnosis of cancers.
摘要翻译: 公开了能够结合磷脂酰肌醇蛋白聚糖3的特定区域的抗体以及基于该抗体产生的人源化抗体。 本发明的抗GPC3抗体与常规抗体相比具有较高的ADCC活性和CDC活性。 本发明的抗体可用作细胞生长抑制剂,抗癌剂和癌症诊断剂。
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公开(公告)号:US4751546A
公开(公告)日:1988-06-14
申请号:US914084
申请日:1986-09-30
申请人: Katuhiko Yamamoto , Takeshi Yoshino , Michihiro Shiina , Shigenori Goto , Masayoshi Hirai , Shiro Hashimoto , Hisashi Hamada
发明人: Katuhiko Yamamoto , Takeshi Yoshino , Michihiro Shiina , Shigenori Goto , Masayoshi Hirai , Shiro Hashimoto , Hisashi Hamada
CPC分类号: G03B17/18
摘要: A display device for a camera has a display panel with a digital display unit having seven display segments disposed in a figure-eight shape. The digital display unit displays the number of exposed frames or other exposure information, and in addition, a portion of display segments is utilized for display or for indicating an alarm condition of the camera. In order to clearly recognize the display or alarm of the camera conditions, a character or symbol representative of the display content or alarm content is disposed near a display segment used for both numerical display, and camera condition display or alarm. A display of the film winding state is performed by flashing the laterally elongated display segments positioned between patterns formed sideways of the digital display unit and symbolizing a film supply section and a film winding section.
摘要翻译: 用于相机的显示装置具有显示面板,其具有数字显示单元,该数字显示单元具有以八字形状设置的七个显示段。 数字显示单元显示曝光帧数或其他曝光信息,另外,显示段的一部分用于显示或指示照相机的报警状态。 为了清楚地识别相机条件的显示或报警,表示显示内容或报警内容的字符或符号被布置在用于数字显示和相机条件显示或报警的显示段附近。 通过闪烁位于数字显示单元侧面形成的图案之间的横向细长显示区域,并且表示胶片供应部分和胶片卷绕部分来执行胶片卷绕状态的显示。
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公开(公告)号:US4720721A
公开(公告)日:1988-01-19
申请号:US13871
申请日:1987-02-12
申请人: Hisashi Hamada , Katsuhiko Yamamoto , Takeshi Yoshino , Masayoshi Hirai , Shiro Hashimoto , Michihiro Shiina , Shigenori Goto
发明人: Hisashi Hamada , Katsuhiko Yamamoto , Takeshi Yoshino , Masayoshi Hirai , Shiro Hashimoto , Michihiro Shiina , Shigenori Goto
CPC分类号: G03B1/60
摘要: A film wind-up control apparatus of a camera in which a film is transported in zigzag direction passing around at least a guide roller located before an exposure station, is adapted to advance the film a predetermined length of the film when an exposure is made in a predetermined period of time and an extra length in addition to the predetermined length after the predetermined period of time has elapsed, so as to advance that part of the film which was previously positioned around the guide roller, beyond the exposure station. The apparatus is also adapted to indicate the number of possible exposures with one decrement every other occurrence of the extra length of film advance. In this way, film that has become permanently curled around the guide roller never comes to rest in the exposure station; but at the same time, the count of remaining frames is kept accurate.
摘要翻译: 一种照相机的胶片卷绕控制装置,其中胶片以至少位于曝光站之前的引导辊绕过的Z字形方向传送,适于在胶片曝光时使胶片前进预定长度 除了经过预定时间段之后的预定长度,预定的时间段和额外的长度,以使先前位于引导辊周围的胶片的那部分超出曝光站。 该装置还适于指示可能的曝光次数,其中一次减量,每隔一次出现额外的胶片提前长度。 以这种方式,在导辊周围变得永久卷曲的胶片从未在曝光台中静止; 但与此同时,剩余帧的计数仍然保持准确。
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公开(公告)号:US4505562A
公开(公告)日:1985-03-19
申请号:US536398
申请日:1983-09-27
CPC分类号: G03B17/30 , G03B1/48 , G03B1/58 , G03B2217/268
摘要: In a camera of the type having a film supply chamber opening at the bottom of the camera into which a container including a coiled strip film with its leader previously drawn out is inserted for film loading, a film supporting apparatus for holding the loaded film flat in film plane comprises a pressure plate and a holding frame for resiliently holding the pressure plate in cantilever fashion. The pressure plate can be displaced in the direction parallel to optical axis of the camera for assured advancement of the film to a film take-up chamber.
摘要翻译: 在具有在相机底部开口的胶片供给室的类型的照相机中,将包括先前拉出的前导件的卷绕带状薄膜的容器插入其中以进行胶片装载,用于将加载的胶片保持在其中的胶片支撑装置 膜平面包括压板和用于以悬臂方式弹性地保持压板的保持框架。 压板可以在平行于照相机的光轴的方向上移位,以确保胶片进入胶片卷取室。
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公开(公告)号:US4400074A
公开(公告)日:1983-08-23
申请号:US353031
申请日:1982-03-01
申请人: Kazuhiko Akiyama , Takeshi Yoshino , Michihiro Shiina , Shigeo Sato , Tetsuo Nishizawa , Toshio Yoshida , Nobuo Kobayashi
发明人: Kazuhiko Akiyama , Takeshi Yoshino , Michihiro Shiina , Shigeo Sato , Tetsuo Nishizawa , Toshio Yoshida , Nobuo Kobayashi
CPC分类号: G03B17/425
摘要: An automatic rewinding camera wherein an automatic advance of the photographic film by one frame is caused by shutter release operation and rewinding of the photographic film is automatically started when the film is prevented from further advance. The camera has a film-driven sprocket wheel, by the rotation of which film movement signals are produced. A timer circuit maintains, during the passage of a predetermined active time which is shorter than the time required to advance the photographic film by one frame, the camera motor in forward rotation so as to advance the photographic film. The timer circuit is reset by the film movement signals. But when those film signals stop, that is, when the film is fully extended from the cartridge, then the timer is not reset; and the measurement of the full predetermined active time, by the timer, without resetting, results in the motor being reversed to rewind the film.
摘要翻译: 一种自动倒带摄像机,其中通过快门释放操作引起摄影胶片自动前进一帧,并且当防止胶片进一步前进时,照相胶片的倒带自动开始。 照相机具有胶片驱动的链轮,通过产生胶片移动信号的旋转。 定时器电路在比预定的活动时间短的过程中保持照相胶片前进一帧所需的时间,以使照相胶片前进。 定时器电路由胶片移动信号复位。 但是当这些电影信号停止时,也就是说,当胶片从墨盒完全伸出时,定时器不复位; 并且通过定时器对整个预定的活动时间进行测量而不进行复位,导致电动机被反转以倒带。
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6.
公开(公告)号:US4085412A
公开(公告)日:1978-04-18
申请号:US654757
申请日:1976-02-03
申请人: Takeshi Yoshino
发明人: Takeshi Yoshino
CPC分类号: G03B17/20 , G03B17/24 , G03B17/245 , G03B2217/243
摘要: In a camera body there are provided a light source, information carrying discs illuminated by the light source, and a half-mirror for dividing the light from the information carrying discs into a light beam directed to the viewfinder and a light beam directed to the film. In the optical path of the light beam directed to the film is provided a light shielding shutter blade to prevent the light from reaching the film when the information is not desired to be recorded on the film. The information carying discs are rotatably mounted in the camera body and carry various characters to be recorded on the film. The information carrying discs are manually operable from outside of the camera body by manually operable dials. The dials are protected from being accidentally moved by a cover. A switch operating pin is operated by the cover so that the light source is turned on when the cover is opened and the light source is momentarily turned on to record the information on the film upon release of the shutter mechanism in the camera when the cover is closed.
摘要翻译: 在相机机体中,提供了一个光源,由光源照亮的信息承载盘,以及用于将来自信息传送盘的光分成指向取景器的光束的半透镜和指向胶片的光束 。 在指向胶片的光束的光路中设置有遮光快门叶片,以防止当信息不希望记录在胶片上时光到达胶片。 信息盘可旋转地安装在相机主体中,并携带要记录在胶片上的各种字符。 通过手动操作的拨盘可以从相机主体的外部手动操作信息传送盘。 表盘保护不被意外地被盖子移动。 开关操作销由盖子操作,使得当盖打开时光源被打开并且光源被瞬间打开以在盖子被释放时在相机中释放快门机构时将信息记录在胶片上 关闭。
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公开(公告)号:US08120824B2
公开(公告)日:2012-02-21
申请号:US12267002
申请日:2008-11-07
申请人: Daijiro Saito , Takeshi Yoshino
发明人: Daijiro Saito , Takeshi Yoshino
IPC分类号: H04N1/04
CPC分类号: H04N1/506
摘要: An image forming apparatus including: an image forming section which forms an image on a photosensitive drum based on a reference signal which being an image write control signal of a predetermined cycle; a measuring section which detects a rotational velocity of the photosensitive drum and measures a velocity fluctuation distribution in time period of one rotation of the drum; a storage section which stores a correction value as a correction data table for each type of recording sheets, wherein the correction value is obtained based on the velocity fluctuation distribution; and a control section which corrects the cycle of the reference signal by referring the correction data table corresponding to a selected type of recording sheets, and controls the image forming section to form the image on the photosensitive drum based on the reference signal with the corrected cycle.
摘要翻译: 一种图像形成装置,包括:图像形成部,其基于作为预定周期的图像写入控制信号的参考信号在感光鼓上形成图像; 测量部分,其检测感光鼓的旋转速度并测量滚筒的一个旋转的时间段内的速度波动分布; 存储部分,其将校正值存储为每种类型的记录片材的校正数据表,其中基于速度波动分布获得校正值; 以及控制部,其通过参照与所选择的记录纸张类型相对应的校正数据表来校正参考信号的周期,并且基于具有校正周期的参考信号来控制图像形成部分以在感光鼓上形成图像 。
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公开(公告)号:US20070190599A1
公开(公告)日:2007-08-16
申请号:US10583795
申请日:2005-07-08
申请人: Kiyotaka Nakano , Takeshi Yoshino , Jun-Ichi Nezu , Hiroyuki Tsunoda , Tomoyuki Igawa , Hiroko Konishi , Megumi Tanaka , Izumi Sugo , Shigeto Kawai , Takahiro Ishiguro , Yasuko Kinoshita
发明人: Kiyotaka Nakano , Takeshi Yoshino , Jun-Ichi Nezu , Hiroyuki Tsunoda , Tomoyuki Igawa , Hiroko Konishi , Megumi Tanaka , Izumi Sugo , Shigeto Kawai , Takahiro Ishiguro , Yasuko Kinoshita
CPC分类号: C07K16/28 , C07K7/06 , C07K14/47 , C07K16/303 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/732 , C07K2317/734 , C07K2317/92
摘要: An antibody capable of binding to a specific region of glypican 3, as well as a humanized antibody created based on that antibody are disclosed. The anti-GPC3 antibody of the invention has a higher ADCC activity and CDC activity compared with those of a conventional antibody. The antibody of the present invention is useful as a cell growth inhibitor, an anticancer agent and an agent for diagnosis of cancers.
摘要翻译: 公开了能够结合磷脂酰肌醇蛋白聚糖3的特定区域的抗体以及基于该抗体产生的人源化抗体。 本发明的抗GPC3抗体与常规抗体相比具有较高的ADCC活性和CDC活性。 本发明的抗体可用作细胞生长抑制剂,抗癌剂和癌症诊断剂。
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公开(公告)号:US07110017B2
公开(公告)日:2006-09-19
申请号:US10383048
申请日:2003-03-06
申请人: Takeshi Yoshino , Kenji Izumiya , Kouichi Takaki
发明人: Takeshi Yoshino , Kenji Izumiya , Kouichi Takaki
IPC分类号: B41J2/435
CPC分类号: H03K5/1506 , G06K15/1219 , H03K5/135 , H04N1/053 , H04N2201/04784 , H04N2201/04789
摘要: There is described a signal controlling circuit particularly used in a printer or copier. The circuit includes a delay chain section to generate a plurality of delayed clock signals, a synchronized signal detecting section to detect a number of delay stages, a total delay time of which is equivalent to a single period of the reference clock signal, based on delayed clock signals synchronized with an index signal and are selected from the plurality of delayed clock signals, an index signal counting section to count index signals inputted into the index signal counting section, a phase shift calculating section to calculate a phase shift amount in respect to the reference clock signal, and a delayed clock selecting section to select a specific delayed clock signal out of the plurality of delayed clock signals in an alternative way, so as to output the specific delayed clock signal to an external section.
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10.
公开(公告)号:US4134656A
公开(公告)日:1979-01-16
申请号:US835740
申请日:1977-09-22
申请人: Takeshi Yoshino
发明人: Takeshi Yoshino
摘要: In a collapsible mount type camera, a transmission pin provided in a lens barrel is movable back and forth as a distance ring or aperture size control ring is rotated. The rear end of the transmission pin is projected rearward out of the lens barrel. The rear end of the pin is integrally fixed to a radially extending lever which extends beyond the periphery of the lens barrel. On the outer end of the radially extending lever abuts a rear end of an intermediate lever pivotally mounted in a camera body. When the lens barrel is retracted into the camera body, the lens barrel with the transmission pin is not obstructed by the intermediate lever.
摘要翻译: 在可折叠安装型照相机中,设置在镜筒中的传输销可随着距离环或孔径尺寸控制环旋转而前后移动。 传输销的后端向后突出到镜筒外。 销的后端一体地固定到延伸超过镜筒的周边的径向延伸的杆上。 在径向延伸的杆的外端上与枢轴安装在相机机体中的中间杆的后端相接。 当镜筒缩回相机机身时,带传动销的镜筒不会被中间杆挡住。
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