公开(公告)号：US09195043B2

公开(公告)日：2015-11-24

申请号：US13218181

申请日：2011-08-25

申请人： Kunal Ghosh ,  Laurie Burns ,  Abbas El Gamal ,  Mark J. Schnitzer ,  Eric Cocker ,  Tatt Wei Ho

发明人： Kunal Ghosh ,  Laurie Burns ,  Abbas El Gamal ,  Mark J. Schnitzer ,  Eric Cocker ,  Tatt Wei Ho

IPC分类号： H04N7/18 ,  G02B21/16 ,  G02B21/36

CPC分类号： A61B5/0071 ,  A61B5/0042 ,  A61B5/0082 ,  A61B5/489 ,  A61B90/20 ,  A61B2090/306 ,  A61B2503/40 ,  A61B2503/42 ,  A61B2562/0233 ,  A61B2562/04 ,  A61B2576/026 ,  G01N21/6458 ,  G02B3/0087 ,  G02B21/0008 ,  G02B21/008 ,  G02B21/16 ,  G02B21/36 ,  G02B21/361 ,  G02B21/362 ,  G02B21/365 ,  G02B27/141 ,  G06T7/0012 ,  G06T2207/30016 ,  G06T2207/30101 ,  H04N5/2254 ,  H04N5/2256 ,  H04N5/23296

摘要： Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.

摘要翻译： 为显微镜成像解决方案实施了系统，方法和设备。 本公开的一个实施方案涉及落射荧光显微镜。 显微镜包括包括光学传感器阵列的图像捕获电路。 光学布置被配置为在至少0.5mm 2的视场内将小于约1mW的激发光引导到目标物体，并将由激发光引起的外延荧光发射引导到光学传感器阵列。 光学传感器的光学布置和阵列各自足够靠近目标物体，以便为视野的图像提供至少2.5μm的分辨率。

公开(公告)号：US20120062723A1

公开(公告)日：2012-03-15

申请号：US13218181

申请日：2011-08-25

申请人： Kunal Ghosh ,  Laurie Burns ,  Abbas El Gamal ,  Mark J. Schnitzer ,  Eric Cocker ,  Tatt Wei Ho

发明人： Kunal Ghosh ,  Laurie Burns ,  Abbas El Gamal ,  Mark J. Schnitzer ,  Eric Cocker ,  Tatt Wei Ho

IPC分类号： H04N7/18

CPC分类号： A61B5/0071 ,  A61B5/0042 ,  A61B5/0082 ,  A61B5/489 ,  A61B90/20 ,  A61B2090/306 ,  A61B2503/40 ,  A61B2503/42 ,  A61B2562/0233 ,  A61B2562/04 ,  A61B2576/026 ,  G01N21/6458 ,  G02B3/0087 ,  G02B21/0008 ,  G02B21/008 ,  G02B21/16 ,  G02B21/36 ,  G02B21/361 ,  G02B21/362 ,  G02B21/365 ,  G02B27/141 ,  G06T7/0012 ,  G06T2207/30016 ,  G06T2207/30101 ,  H04N5/2254 ,  H04N5/2256 ,  H04N5/23296

摘要： Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.

摘要翻译： 为显微镜成像解决方案实施了系统，方法和设备。 本公开的一个实施方案涉及落射荧光显微镜。 显微镜包括包括光学传感器阵列的图像捕获电路。 光学布置被配置为在至少0.5mm 2的视场内将小于约1mW的激发光引导到目标物体，并将由激发光引起的外延荧光发射引导到光学传感器阵列。 光学传感器的光学布置和阵列各自足够靠近目标物体，以便为视野的图像提供至少2.5μm的分辨率。