摘要:
Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.
摘要:
Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.
摘要:
Characteristics of a chemical or biological sample are detected using an approach involving light detection. According to an example embodiment of the present invention, an assaying arrangement including a light detector is adapted to detect light from a sample, such as a biological material. A signal corresponding to the detected light is used to characterize the sample, for example, by detecting a light-related property thereof. In one implementation, the assaying arrangement includes integrated circuitry having a light detector and a programmable processor, with the light detector generating a signal corresponding to the light and sending the signal to the processor. The processor provides an output corresponding to the signal and indicative of a characteristic of the sample.
摘要:
Characteristics of a chemical or biological sample are detected using an approach involving light detection. According to an example embodiment of the present invention, an assaying arrangement including a light detector is adapted to detect light from a sample, such as a biological material. A signal corresponding to the detected light is used to characterize the sample, for example, by detecting a light-related property thereof. In one implementation, the assaying arrangement includes integrated circuitry having a light detector and a programmable processor, with the light detector generating a signal corresponding to the light and sending the signal to the processor. The processor provides an output corresponding to the signal and indicative of a characteristic of the sample.
摘要:
Imaging is carried out using multiple views (e.g., from a single monolithic device) to generate an image. According to an example embodiment, a scene is imaged using disjoint sensors beyond a designated focal plane to obtain multiple views of common points in the focal plane. For the common points, the multiple views are processed to compute a depth of field, and the computed depth of field to generate an image.
摘要:
A user-programmable interconnect architecture, which may be used for logic arrays for digital and analog system design, is disclosed. In one embodiment, a plurality of logic cells or modules in a matrix are connected by vertical and horizontal wiring channels. The wiring channels may in turn be programmed by the user to interconnect the various logic cells to implement the required logic function. The wiring channels comprise wiring segments connected by normally open reconfigurable programmable elements situated at the intersection of any two segments to be connected.
摘要:
An image sensor formed using a CMOS process is described herein which includes a pixel array core of phototransistors whose conductivities are related to the magnitude of light impinging upon the phototransistors. The analog signals generated by the phototransistors are converted to a serial bit stream by an A/D converter connected at the output of each phototransistor and formed in the immediate area of each phototransistor within the array core. Thus, a separate digital stream for each pixel element is output from the array core, and parasitic effects and distortion are minimized. In one embodiment, a filter circuit is connected to an output of the array core for converting the individual digital streams from each pixel element to multi-bit values corresponding to the intensity of light impinging on the phototransistor.
摘要:
An improved cell for use in a mask programmable gate array is disclosed herein. The preferred cell comprises two compute sections, each comprising two pairs of medium size P and N-channel transistors, two small N-channel transistors, and a single small P-channel transistor. Each cell also comprises a high efficiency drive section containing a single bipolar pull-up transistor, a large N-channel pull-down transistor, and a small P-channel transistor. By using this cell, an extremely high compute capability per die area is achieved.
摘要:
Characteristics of a chemical or biological sample are detected using an approach involving light detection. According to an example embodiment of the present invention, an assaying arrangement including a light detector is adapted to detect light from a sample, such as a biological material. A signal corresponding to the detected light is used to characterize the sample, for example, by detecting a light-related property thereof. In one implementation, the assaying arrangement includes integrated circuitry having a light detector and a programmable processor, with the light detector generating a signal corresponding to the light and sending the signal to the processor. The processor provides an output corresponding to the signal and indicative of a characteristic of the sample.
摘要:
A new adaptive pixel architecture, folded-multiple-capture (FMC), integrates synchronous self-reset and multiple capture schemes and advantageously eliminates the requirement of a high-frame-rate sensor array, which is essential for conventional image sensors with high dynamic range. The FMC comprises a per-pixel analog-front-end (AFE), a fine analog-digital convertor (ADC) stage, and a digital-signal-processor/controller (DSPC) stage. The AFE performs programmable gain control, synchronous self-reset, sample-and-hold, and enables disturbance detection. In the AFE, a comparator compares an integrator output with a threshold voltage and produces a binary sequence accordingly. The ADC utilizes the binary sequence and the folded multiple capture signals to estimate photocurrent. An image sensor embodying the present invention adapts integration time to signal level, has minimal per-pixel hardware requirement, provides a very high dynamic range, about 120 dB or more, at high speed, about 1,000 frames/s or more, detects and corrects subframe disturbances, and consumes significantly less power.