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公开(公告)号：US12296094B1
公开(公告)日：2025-05-13
申请号：US17239880
申请日：2021-04-26
Applicant: Tel HaShomer Medical Research Infrastructure and Services Ltd. , Ramot at Tel-Aviv University Ltd.
Inventor： Moshe Ashkenazi , Gil Sokol , Ori Efrati , Itzik Mashiach , Diana Sverdlov , Ortal Shtayman , Imry Ben Avi , Daniel Sorkin
Abstract: Pulmonary treatment methods and systems. During pulmonary treatment breath cycles, a hold period of elevated inspiration pressure may promote lung region filling (and potentially recruitment) via collateral airways. Expectoration is promoted by dropping from the inspiration pressure to an undershoot pressure; de-recruitment (e.g., by airway collapse) is mitigated by raising the undershoot pressure to a positive expiratory pressure (PEP) during expiration phase. Breath cycles with a period of post-PEP suction may also be administered. Respiratory therapy systems may be programmed or re-programmed to administer this pressure protocol. In some embodiments, a system includes a hand-held unit including a patient mouthpiece, a base unit which provides pressurized gas to the mouthpiece, an electronically controllable valve in the hand-held unit for providing therapy maneuvers such as PEP (Positive Expiratory Pressure) through the mouthpiece, and a computing unit which instructs the hand-held unit to perform therapy maneuvers.
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公开(公告)号：US20230360220A1
公开(公告)日：2023-11-09
申请号：US18223106
申请日：2023-07-18
Applicant: Ramot at Tel-Aviv University Ltd. , Tel HaShomer Medical Research Infrastructure and Services Ltd.
Inventor： Ygal ROTENSTREICH , Ifat SHER ROSENTHAL , Haim SUCHOWSKI , Michael MREJEN , Shahar KATZ
CPC classification number: G06T7/0016 , A61B5/026 , A61B3/11 , G06T2207/10024 , G06T2207/20081 , G06T2207/30041 , G06T2207/30104
Abstract: A method of diagnosing a condition of a subject, comprises: receiving image data of an anterior of an eye of the subject, and analyzing the image data to detect at least one of: flow of individual blood cells in libmal or conjunctival blood vessels of the eye, morphology of limbal or conjunctival blood vessels. The method also comprises determining the condition of the subject based on the detection(s).
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公开(公告)号：US11779459B2
公开(公告)日：2023-10-10
申请号：US17349152
申请日：2021-06-16
Inventor： Ehud Raanani , Boris Orlov , Boaz Harari , Oded Meiri , Lichen Rozitsky
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/243 , A61F2/2436 , A61F2/2457 , A61F2220/0016 , A61F2220/0058 , A61F2220/0075 , A61F2230/005 , A61F2230/0013 , A61F2230/0078 , A61F2250/006
Abstract: Apparatus and methods are described including a valve frame defining a frame aperture and at least one arm attached to a portion of the valve frame on a ventricular side of said frame aperture. The at least one arm is configured to extend radially from the portion of the valve frame such that a chord receiving surface of the arm is sized and shaped to deploy among a region of the chords of the native mitral valve. The arm is curved, with an interior of the arm facing a direction in which the valve frame is configured to be rotated during deployment of the prosthetic mitral valve apparatus within the native mitral valve and with the arm having a concavely rounded leading edge facing at least partially in a circumferential direction. Other applications are also described.
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公开(公告)号：US11699236B2
公开(公告)日：2023-07-11
申请号：US17487082
申请日：2021-09-28
Applicant: Ramot at Tel-Aviv University Ltd. , Tel HaShomer Medical Research Infrastructure and Services Ltd.
Inventor： Yitzhak Avital , Nahum Kiryati , Eli Konen , Arnaldo Mayer
CPC classification number: G06T7/11 , A61B5/0042 , A61B5/055 , A61B5/4381 , A61B5/7267 , A61B34/20 , A61B34/32 , G01R33/5602 , G01R33/5608 , G06N3/08 , G06T2200/04 , G06T2207/10092 , G06T2207/20081 , G06T2207/20084 , G06T2207/20132 , G06T2207/20156 , G06T2207/30016 , G06T2207/30081 , G06T2207/30096
Abstract: There is provided a computer implemented method of automatic segmentation of three dimensional (3D) anatomical region of interest(s) (ROI) that includes predefined anatomical structure(s) of a target individual, comprising: receiving 3D images of a target individual, each including the predefined anatomical structure(s), each 3D image is based on a different respective imaging modality. In one implementation, each respective 3D image is inputted into a respective processing component of a multi-modal neural network, wherein each processing component independently computes a respective intermediate, and the intermediate outputs are inputted into a common last convolutional layer(s) for computing the indication of segmented 3D ROI(s). In another implementation, each respective 3D image is inputted into a respective encoding-contracting component a multi-modal neural network, wherein each encoding-contracting component independently computes a respective intermediate output. The intermediate outputs are inputted into a single common decoding-expanding component for computing the indication of segmented 3D ROI(s).
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公开(公告)号：US20230146263A1
公开(公告)日：2023-05-11
申请号：US17964299
申请日：2022-10-12
Inventor： Gilad LAVI , Yoseph GLOVINSKY , Vadim SHMUKLER , Nir ISRAELI
CPC classification number: A61F9/00763 , A61B17/00234 , A61F9/00781 , A61B2017/00132 , A61B2017/00353
Abstract: assembly configured for removably interconnecting between the hand-held probe device and the rotating motor device. The hand-held probe device is disposable and comprises a housing having proximal and distal ends, a rotatable cutting tool extending distally from the distal end of the housing and being configured for cutting and removing tissue during rotation, and a transmission assembly passing inside the housing between the proximal and distal ends and being configured for transmitting rotational power to the rotatable cutting tool. The connection assembly is configured for engaging between the rotating motor device and the transmission assembly to thereby controllably rotate the cutting tool and remove tissue. In some embodiments, the apparatus includes a control unit for controlling operation of the apparatus, the control unit comprises an activation mechanism for activating the rotatable cutting tool, and a controller configured for operating the activation mechanism to generate a single fixed activation signal of a known intensity and duration during a predetermined time interval, thereby restricting operation of the cutting tool during the time interval to the single activation signal only.
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Patent Agency Ranking
公开(公告)号：US11565091B2
公开(公告)日：2023-01-31
申请号：US16461383
申请日：2017-11-16
Applicant: Ramot at Tel-Aviv University Ltd. , Tel HaShomer Medical Research Infrastructure and Services Ltd. , Hadasit Medical Research Services and Development Ltd.
Inventor： Ofer Barnea , Omer Doron
IPC: A61M27/00 , A61M25/10 , A61M25/00 , A61B5/03 , A61M60/122 , A61M60/268
Abstract: A method for influencing cerebral perfusion in a patient by modifying a volume of a volume adaptor introduced into a cerebral ventricle of the patient, the method comprising identifying a timing of a cerebral blood inflow and/or outflow in a cardiac activity of the patient, modifying a volume of the volume adaptor in synchronization to the identified timing of the cerebral blood flow, to an amount sufficient to modify an intracranial pressure in the cerebral ventricle, such that a flow of the cerebral blood flow is enhanced. In some exemplary embodiments of the invention, the inflation duration of the volume adapter is short relative to the cardiac cycle.
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公开(公告)号：US11534126B2
公开(公告)日：2022-12-27
申请号：US17163934
申请日：2021-02-01
Inventor： Miriam Sklair-Levy , Arnaldo Mayer , Shmuel Yitzhak Pfeffer
IPC: G06T7/00 , G06T7/11 , G06T7/13 , A61B6/04 , A61B6/00 , G06V10/46 , G06V10/44 , G06V10/50 , G06V10/42 , G06T7/44 , A61B6/12
Abstract: Apparatus for diagnosing breast cancer, the apparatus comprising a controller having a set of instructions executable to: acquire a contrast enhanced region of interest (CE-ROI) in an X-ray image of a patient's breast, the X-ray image comprising X-ray pixels that indicate intensity of X-rays that passed through the breast to generate the image; determine a texture neighborhood for each of a plurality of X-ray pixels in the CE-ROI, the texture neighborhood for a given X-ray pixel of the plurality of X-ray pixels extending to a bounding pixel radius of BPR pixels from the given pixel; generate a texture feature vector (TF) having components based on the indications of intensity provided by a plurality of X-ray pixels in the CE-ROI that are located within the texture neighborhood; and use a classifier to classify the texture feature vector TF to determine whether the CE-ROI is malignant.
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公开(公告)号：US20220362021A1
公开(公告)日：2022-11-17
申请号：US17624437
申请日：2020-07-03
Inventor： Alain Elie SERRAF , Mila Shai Raziel TEJMAN-YARDEN , Roey SHAFRIR
IPC: A61F2/24
Abstract: Apparatus for coupling a prosthetic chorda to an atrioventricular valve leaflet, the apparatus comprising: a neochorda delivery system comprising a steerable and pushable catheter housing a neochorda attached to a neochorda puncture needle, the catheter operable to push the puncture needle to puncture and thread the neochorda through a papillary muscle of a ventricle; a retriever system comprising a catheter housing a grabber operable to capture the neochorda puncture needle after being threaded through the papillary muscle and withdraw the neochorda puncture needle and neochorda from the ventricle; and a tissue clamping system comprising a catheter housing distal and proximal tissue clamps deployable to clamp a region of an atrioventricular valve between them and hold the region so that it may be punctured by the puncture needle to deliver the neochorda through the leaflet and to the papillary muscle.
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公开(公告)号：US20220296416A1
公开(公告)日：2022-09-22
申请号：US17828749
申请日：2022-05-31
Inventor： Gilad Lavi , Yoseph Glovinsky , Vadim Shmukler , Nir Israeli
IPC: A61F9/007
Abstract: Medical devices and methods for removing a predetermined portion of soft tissue from a target tissue layer, thereby creating a channel between two side walls of the target tissue layer, are described. The medical device is a cutting tool comprising: an elongated round body extending along a longitudinal axis and having a uniform outer cross-section at a proximal side thereof; a cutting portion at a distal side of the elongated body, comprising at a distal end thereof a cutting edge of a first cross-section being smaller than said outer cross-section, and a distally and continuously decreasing outer cross-section; and a chamber extending along the longitudinal axis inside the cutting tool from said cutting portion, the chamber having dimensions enabling storing of the removed soft tissue portion inside the chamber thereby providing a validation to the channel creation.
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公开(公告)号：US20220146311A1
公开(公告)日：2022-05-12
申请号：US17582741
申请日：2022-01-24
Inventor： Yuval GARINI , Irena BRONSHTEIN-BERGER , Iris BARSHACK
Abstract: A spectral imaging device includes an imager, a scanning stage to establish relative motion between the imager and a sample in a scanning direction and an optical system controlling a light characteristic of a light beam constituting an image of the sample to the imager. The optical system includes a light varying element to receive the light beam and provide an output light beam with spatially varying light characteristic over a cross-section thereof. A set of redirecting optical elements direct light rays from the sample to form the light beam, and to focus the output light beam onto the imager. A controller controls the scanning stage and the imager to capture a plurality of image frames with an overlap including a defined shift that is greater than 1 pixel along the scanning direction between consecutive image frames. A computing device consolidates image data to provide an image of the sample.
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