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    Distal cooling distribution system for a medical device
    1.
    发明授权
    Distal cooling distribution system for a medical device 有权
    用于医疗设备的远端冷却分配系统

    公开(公告)号：US09211393B2

    公开(公告)日：2015-12-15

    申请号：US11476416

    申请日：2006-06-28

    申请人： Yixin Hu ,  Vladimir Tzonev ,  Teresa Ann Mihalik ,  Benoit Thibault ,  Dan Wittenberger ,  Miriam Lane ,  Cristian Petre

    发明人： Yixin Hu ,  Vladimir Tzonev ,  Teresa Ann Mihalik ,  Benoit Thibault ,  Dan Wittenberger ,  Miriam Lane ,  Cristian Petre

    IPC分类号： A61M25/10 ,  A61M25/00 ,  A61M25/01 ,  A61B18/02 ,  A61B17/22 ,  A61B18/00

    CPC分类号： A61M25/1025 ,  A61B18/02 ,  A61B2017/22051 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61M2025/0004 ,  A61M2025/0175 ,  A61M2025/1061

    摘要： The present invention may include a medical device having a handle, a catheter coupled to the handle, and an expandable element coupled to the catheter. The medical device may also include first and second elongate bodies that traverse a length of the handle and the catheter. A housing may be disposed within the handle, with the housing defining a first opening able to receive a portion of the first elongate body, a second opening able to receive a portion of the second elongate body, and a third opening opposite the first and second openings able to receive a portion of both the first and second elongate bodies. A separation element may be disposed within the housing, with the separation element defining a path able to receive a portion of the second elongate body, and whereby a portion of the first elongate body forms a loop around the separation element.

    摘要翻译： 本发明可以包括具有手柄，耦合到手柄的导管和联接到导管的可扩张元件的医疗装置。 医疗装置还可以包括穿过手柄和导管的一段长度的第一和第二细长体。 壳体可以设置在手柄内，其中壳体限定能够容纳第一细长主体的一部分的第一开口，能够容纳第二细长主体的一部分的第二开口，以及与第一和第二 开口能够容纳第一和第二细长体的一部分。 分离元件可以设置在壳体内，其中分离元件限定能够接收第二细长主体的一部分的路径，并且由此第一细长主体的一部分围绕分离元件形成环。

    Fluid control system for a medical device
    2.
    发明授权
    Fluid control system for a medical device 有权
    用于医疗设备的流体控制系统

    公开(公告)号：US09027389B2

    公开(公告)日：2015-05-12

    申请号：US13526620

    申请日：2012-06-19

    申请人： Marwan Abboud ,  Rachid Mahrouche ,  Teresa Ann Mihalik ,  Chadi Harmouche ,  Jean-Luc Pageard ,  John W. Lehmann

    发明人： Marwan Abboud ,  Rachid Mahrouche ,  Teresa Ann Mihalik ,  Chadi Harmouche ,  Jean-Luc Pageard ,  John W. Lehmann

    IPC分类号： A61B18/02 ,  G01M3/28 ,  A61B17/00 ,  A61B18/00

    CPC分类号： A61B18/02 ,  A61B2017/00084 ,  A61B2018/0022 ,  A61B2018/00577 ,  A61B2018/00744 ,  A61B2018/00863 ,  A61B2018/00898 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61B2018/0268 ,  G01M3/02 ,  G01M3/2846

    摘要： The present invention provides a medical device having an elongate body with both a proximal end and a distal end, wherein the elongate body defines an intake lumen and an exhaust lumen. The medical device also has a first pliable element defining a cooling chamber disposed at a point along the elongate body, with the cooling chamber being in fluid communication with the intake lumen and the exhaust lumen. A second pliable element is provided which at least partially encloses the first pliable element, thereby defining a junction between the first and second pliable element. A check valve is included which is in fluid communication with the junction between the first pliable element and second pliable element, the valve further being in fluid communication with the exhaust lumen. Additionally, the medical device may include sensors or other monitoring means in fluid communication with the junction and the cooling chamber.

    摘要翻译： 本发明提供一种医疗装置，其具有具有近端和远端两者的细长主体，其中细长主体限定进气腔和排气腔。 医疗装置还具有限定设置在沿着细长体的点处的冷却室的第一柔性元件，其中冷却室与进气腔和排气腔流体连通。 提供了第二柔韧元件，其至少部分地包围第一柔韧元件，从而限定第一和第二柔韧元件之间的接合部。 包括止回阀，其与第一柔韧元件和第二柔韧元件之间的接合部流体连通，所述阀还与排气腔流体连通。 此外，医疗装置可以包括与接头和冷却室流体连通的传感器或其它监测装置。

    Contact assessment of balloon catheters
    5.
    发明授权
    Contact assessment of balloon catheters 有权
    球囊导管接触评估

    公开(公告)号：US07442190B2

    公开(公告)日：2008-10-28

    申请号：US11129205

    申请日：2005-05-13

    申请人： Marwan Abbound ,  Teresa Ann Mihalik ,  Johnny Al Asmar ,  Chadi Harmouche

    发明人： Marwan Abbound ,  Teresa Ann Mihalik ,  Johnny Al Asmar ,  Chadi Harmouche

    IPC分类号： A61B18/18 ,  A61B5/02

    CPC分类号： A61B5/6885 ,  A61B5/053 ,  A61B5/0538 ,  A61B5/6886 ,  A61B18/02 ,  A61B2017/00026 ,  A61B2017/00039 ,  A61B2017/00084 ,  A61B2017/22051 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2090/065

    摘要： A method and system for determining contact assessment includes the steps of positioning a catheter at a tissue treatment site, where the catheter has a proximal end portion and a distal end portion, the proximal end portion defining at least one fluid inlet port and at least one fluid outlet port, an expandable membrane defining a cooling chamber a coolant injection lumen in fluid communication with the at least one fluid inlet port and the cooling chamber, a coolant return lumen in fluid communication with the at least one fluid outlet port and the cooling chamber, the coolant injection tube, the cooling chamber, and the primary coolant return lumen defining a fluid pathway and a temperature sensor located near the coolant return lumen; measuring an internal temperature of the chamber, and modifying the position of the catheter in response to the measured temperature. The method and system can also use a measured impedance to determine contact assessment.

    摘要翻译： 用于确定接触评估的方法和系统包括将导管定位在组织治疗部位的步骤，其中所述导管具有近端部分和远端部分，所述近端部分限定至少一个流体入口端口和至少一个 流体出口端口，限定冷却室的可膨胀膜，与所述至少一个流体入口和所述冷却室流体连通的冷却剂注入腔，与所述至少一个流体出口和所述冷却室流体连通的冷却剂返回内腔 冷却剂注入管，冷却室和第一冷却剂回流腔限定流体通路和位于冷却剂回流腔附近的温度传感器; 测量腔室的内部温度，以及响应于测量的温度改变导管的位置。 该方法和系统还可以使用测量的阻抗来确定接触评估。

    Compliant balloon catheter
    7.
    发明授权
    Compliant balloon catheter 有权
    符合气囊导管

    公开(公告)号：US08425456B2

    公开(公告)日：2013-04-23

    申请号：US12768218

    申请日：2010-04-27

    申请人： Teresa Ann Mihalik ,  Jean-Luc Pageard ,  John W. Lehmann

    发明人： Teresa Ann Mihalik ,  Jean-Luc Pageard ,  John W. Lehmann

    IPC分类号： A61M29/00 ,  A61F7/12

    CPC分类号： A61B18/02 ,  A61B2017/22051 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61M25/1011 ,  A61M2025/1013

    摘要： A catheter includes a first expandable membrane having a first pressurization limit and a second expandable membrane, having a second pressurization limit, wherein the second pressurization limit is greater than the first pressurization limit, the first expandable membrane defines a cooling chamber, the second expandable membrane being disposed around the first expandable membrane to define an junction therebetween. The catheter includes a coolant injection lumen in fluid communication with the at least one fluid inlet port and the cooling chamber, and a primary coolant return lumen in fluid communication with the at least one fluid outlet port and the cooling chamber. The coolant injection tube, the cooling chamber, and the primary coolant return lumen define a first fluid pathway. The catheter further includes a secondary coolant return lumen in fluid communication with the at least one fluid outlet port and the junction. The junction and the secondary coolant return lumen define a second fluid pathway. The catheter provides a fail-safe feature by selecting the appropriate first and second pressurization limits for the first and second expandable membranes.

    摘要翻译： 导管包括具有第一加压极限的第一可膨胀膜和具有第二加压极限的第二可膨胀膜，其中所述第二加压极限大于所述第一加压极限，所述第一可膨胀膜限定冷却室，所述第二可膨胀膜 被布置在第一可膨胀膜周围以限定它们之间的接合部。 所述导管包括与所述至少一个流体入口和所述冷却室流体连通的冷却剂注入腔，以及与所述至少一个流体出口和所述冷却室流体连通的主冷却剂返回内腔。 冷却剂注入管，冷却室和主冷却剂回流腔限定第一流体通路。 导管还包括与至少一个流体出口和接合部流体连通的二次冷却剂返回内腔。 连接点和二次冷却剂回流腔限定第二流体通路。 该导管通过为第一和第二可膨胀膜选择适当的第一和第二加压限制来提供故障安全特征。

    Fluid control system for a medical device
    8.
    发明授权
    Fluid control system for a medical device 有权
    用于医疗设备的流体控制系统

    公开(公告)号：US08225643B2

    公开(公告)日：2012-07-24

    申请号：US12125533

    申请日：2008-05-22

    申请人： Marwan Abboud ,  Rachid Mahrouche ,  Teresa Ann Mihalik ,  Chadi Harmouche ,  Jean-Luc Pageard ,  John W. Lehmann

    发明人： Marwan Abboud ,  Rachid Mahrouche ,  Teresa Ann Mihalik ,  Chadi Harmouche ,  Jean-Luc Pageard ,  John W. Lehmann

    IPC分类号： G01M3/26

    CPC分类号： A61B18/02 ,  A61B2017/00084 ,  A61B2018/0022 ,  A61B2018/00577 ,  A61B2018/00744 ,  A61B2018/00863 ,  A61B2018/00898 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61B2018/0268 ,  G01M3/02 ,  G01M3/2846

    摘要： The present invention provides a medical device having an elongate body with both a proximal end and a distal end, wherein the elongate body defines an intake lumen and an exhaust lumen. The medical device also has a first pliable element defining a cooling chamber disposed at a point along the elongate body, with the cooling chamber being in fluid communication with the intake lumen and the exhaust lumen. A second pliable element is provided which at least partially encloses the first pliable element, thereby defining a junction between the first and second pliable element. Moreover, a check valve is included which is in fluid communication with the junction between the first pliable element and second pliable element, the valve further being in fluid communication with the exhaust lumen. In addition, the medical device may include sensors or other monitoring means in fluid communication with the junction and the cooling chamber.

    摘要翻译： 本发明提供一种医疗装置，其具有具有近端和远端两者的细长主体，其中细长主体限定进气腔和排气腔。 医疗装置还具有限定设置在沿着细长体的点处的冷却室的第一柔性元件，其中冷却室与进气腔和排气腔流体连通。 提供了第二柔韧元件，其至少部分地包围第一柔韧元件，从而限定第一和第二柔韧元件之间的接合部。 此外，包括与第一柔韧元件和第二柔韧元件之间的接合部流体连通的止回阀，阀还与排气腔流体连通。 另外，医疗装置可以包括与接头和冷却室流体连通的传感器或其它监控装置。

    Method and apparatus for inflating and deflating balloon catheters
    9.
    发明授权
    Method and apparatus for inflating and deflating balloon catheters 有权
    球囊导管充气和放气的方法和装置

    公开(公告)号：US07727228B2

    公开(公告)日：2010-06-01

    申请号：US10806995

    申请日：2004-03-23

    申请人： Marwan Abboud ,  Rachid Mahrouche ,  Teresa Ann Mihalik ,  Chadi Harmouche ,  Eric Monger

    发明人： Marwan Abboud ,  Rachid Mahrouche ,  Teresa Ann Mihalik ,  Chadi Harmouche ,  Eric Monger

    IPC分类号： A61B18/18

    CPC分类号： A61B18/02 ,  A61B18/1492 ,  A61B2017/22051 ,  A61B2018/0022 ,  A61B2018/00994 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61M25/1011 ,  A61M25/1018 ,  A61M25/10185

    摘要： A system and method for controlling the inflation, ablation, and deflation of a balloon catheter is provided. The system includes a balloon catheter, a console having a pressurized gas or liquid inflation source, and an umbilical system to deliver pressurized coolant to the balloon catheter. The system comprises a PID (Proportional Integral Derivative) controller or other pressure-sensing device that monitors the amount of pressure and volume within the balloon catheter. During inflation, the pressure and/or volume of fluid within the balloon is maintained at a target amount in order to provide sufficient mechanized pressure against the desired target region. The system limits the inflation pressure such that a safe quantity of gas would be released should a leak occur. If the amount falls below a certain threshold level, gas or fluid egress is presumed and the inflation process is halted.

    摘要翻译： 提供了一种用于控制气囊导管的充气，消融和放气的系统和方法。 该系统包括球囊导管，具有加压气体或液体充气源的控制台，以及将加压的冷却剂输送到球囊导管的脐带系统。 该系统包括PID（比例积分微分）控制器或其他压力感测装置，其监测气囊导管内的压力和体积的量。 在充气期间，气囊内的流体的压力和/或体积保持在目标量，以便提供相对于期望目标区域的足够的机械化压力。 该系统会限制通气压力，以便在发生泄漏时释放出安全数量的气体。 如果该量低于某一阈值水平，则假设气体或流体出口，并且暂停充气过程。