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7 条记录 (耗时 0.017 秒)

    Peptides against autoantibodies causing intolerance to cold and use thereof
    1.
    发明授权
    Peptides against autoantibodies causing intolerance to cold and use thereof 失效
    针对导致不耐寒的自身抗体的肽和其使用

    公开(公告)号：US08440609B2

    公开(公告)日：2013-05-14

    申请号：US10543815

    申请日：2004-01-29

    申请人： Gerd Wallukat ,  Thomas Harrer

    发明人： Gerd Wallukat ,  Thomas Harrer

    IPC分类号： A61K38/08

    CPC分类号： B01J20/3242 ,  A61K38/00 ,  B01D15/3809 ,  B01J20/286 ,  C07K14/4713 ,  C07K14/705 ,  C12N2799/021

    摘要： The invention relates to nucleic acid molecules encoding peptides which are directed against autoantibodies associated with cold allergy, to the peptides themselves, to a pharmaceutical composition comprising said nucleic acid molecules and peptides, and to the use of said nucleic acid molecules and peptides for the treatment of circulatory disorders associated with exposure to cold or intolerance to cold, especially cold allergies.

    摘要翻译： 本发明涉及编码针对与冷变态反应相关的自身抗体的肽，本身涉及包含所述核酸分子和肽的药物组合物的肽的核酸分子，以及所述核酸分子和肽用于治疗的核酸分子 与感冒或不耐寒相关的循环系统疾病，特别是感冒。

    Adjusting the Composition of a Process Gas in a Laser Processing System
    3.
    发明申请
    Adjusting the Composition of a Process Gas in a Laser Processing System 审中-公开
    调整激光加工系统中工艺气体的组成

    公开(公告)号：US20080205471A1

    公开(公告)日：2008-08-28

    申请号：US11994465

    申请日：2005-07-02

    申请人： Thomas Harrer ,  Michael Wessner

    发明人： Thomas Harrer ,  Michael Wessner

    IPC分类号： H01S3/104 ,  H01S3/22

    CPC分类号： B23K26/125 ,  B23K26/123 ,  B23K26/142

    摘要： A laser processing system includes a laser processing means, a gas mixing unit, and a controller. The controller controls and adjusts the composition of the process gas for laser processing. The controller includes a data storage for technology tables by means of which the composition of the process gas is controlled and adjusted.

    摘要翻译： 激光加工系统包括激光加工装置，气体混合装置和控制器。 控制器控制和调整激光加工工艺气体的组成。 控制器包括用于技术表的数据存储器，通过该数据存储器控制和调整处理气体的组成。

    Bob-1 specific T cells and methods to use
    6.
    发明申请
    Bob-1 specific T cells and methods to use 审中-公开
    Bob-1特异性T细胞和使用方法

    公开(公告)号：US20070161108A1

    公开(公告)日：2007-07-12

    申请号：US11582136

    申请日：2006-10-16

    申请人： Ellen Harrer ,  Thomas Harrer

    发明人： Ellen Harrer ,  Thomas Harrer

    IPC分类号： C12Q1/00 ,  C12P1/00 ,  C12N5/08

    CPC分类号： C07K14/47 ,  A61K39/00

    摘要： The present invention refers to the use of Bob-1 protein, fragments or epitopes thereof and/or related sequences in a method to identify, to induce and/or to isolate Bob-1 specific or Bob-1 cross-reactive T-cells, preferably cytotoxic T-lymphocytes (CTL) and CD4+ T-helper cells. The T-cells according to the invention can be used to identify and diagnose various diseases, which are influenced by Bob-1 protein expression. The invention provides further the use of Bob-1 specific and/or Bob-1 cross-reactive T-cells, as well as peptides and/or nucleic acid sequences for inducing Bob-1 specific and/or Bob-1 cross-reactive T-cells, as medicament or vaccine and for the treatment of Bob-1 expressing tumors, lymphomas and autoimmune diseases.

    摘要翻译： 本发明涉及在鉴定，诱导和/或分离Bob-1特异性或Bob-1交叉反应性T细胞的方法中使用Bob-1蛋白，其片段或表位和/或相关序列， 优选细胞毒性T淋巴细胞（CTL）和CD4 + T辅助细胞。 根据本发明的T细胞可用于鉴定和诊断受Bob-1蛋白表达影响的各种疾病。 本发明进一步提供了Bob-1特异性和/或Bob-1交叉反应性T细胞以及肽和/或核酸序列用于诱导Bob-1特异性和/或Bob-1交叉反应性T 细胞，作为药物或疫苗，用于治疗表达Bob-1的肿瘤，淋巴瘤和自身免疫性疾病。