METHOD OF PROTECTING MEMBRANES
    2.
    发明申请
    METHOD OF PROTECTING MEMBRANES 审中-公开
    保护膜的方法

    公开(公告)号:US20120132853A1

    公开(公告)日:2012-05-31

    申请号:US13321468

    申请日:2010-05-20

    申请人: Thorsten Singer

    发明人: Thorsten Singer

    IPC分类号: C09K3/00

    摘要: The present invention relates to a method of protecting membranes by treatment with an aqueous solution containing at least one water-soluble, nucleophilic compound, and the use of this aqueous solution for protecting matrices.

    摘要翻译: 本发明涉及一种通过用含有至少一种水溶性亲核化合物的水溶液进行处理以及使用该水溶液保护基质来保护膜的方法。

    Method for cleaning and isolating nucleic acid using ammonium or phosphonium cationic detergents
    4.
    发明授权
    Method for cleaning and isolating nucleic acid using ammonium or phosphonium cationic detergents 有权
    使用铵或鏻阳离子洗涤剂清洗和分离核酸的方法

    公开(公告)号:US08679744B2

    公开(公告)日:2014-03-25

    申请号:US11572085

    申请日:2005-07-15

    申请人: Thorsten Singer

    发明人: Thorsten Singer

    IPC分类号: C12Q1/68 B01L3/00

    CPC分类号: C12N15/101

    摘要: The present invention relates to a method for cleaning and isolating nucleic acids using cationic detergents with the general formula (I): Y+R1R2R3R4X−  (I) where Y can represent nitrogen or phosphorus R1, R2, R3 and R4 can represent independently from one another an unbranched or branched C1-C20-alkyl residue, C3-C6-alkenyl residue, C3-C6-alkinyl residue and/or a C6-C20-aryl residue as well as a C6-C26-aralkyl residue, and X— can represent an anion of an inorganic or organic single or multi-basic acid.

    摘要翻译: 本发明涉及使用具有通式(I)的阳离子洗涤剂清洗和分离核酸的方法:Y + R1R2R3R4X-(I)其中Y可以表示氮或磷R1,R2,R3和R4可以独立地代表一个 另一个非支链或支链C 1 -C 20烷基残基,C 3 -C 6 - 烯基残基,C 3 -C 6 - 链烷基残基和/或C 6 -C 20芳基残基以及C 6 -C 26 - 芳烷基残基,以及X- 代表无机或有机单碱或多碱的阴离子。

    EXTRACTION OF NUCLEIC ACIDS FROM WAX-EMBEDDED SAMPLES
    5.
    发明申请
    EXTRACTION OF NUCLEIC ACIDS FROM WAX-EMBEDDED SAMPLES 有权
    从嵌入式样品中提取核酸

    公开(公告)号:US20130280787A1

    公开(公告)日:2013-10-24

    申请号:US13703205

    申请日:2011-06-14

    IPC分类号: C12Q1/68

    CPC分类号: C12Q1/6806 C12N15/1003

    摘要: The present invention relates to a method for extracting nucleic acids from a wax-embedded sample, the use of particular solvents for removing wax from a wax-embedded sample in a method for extracting, isolating and/or purifying nucleic acids from a crosslinked wax-embedded sample as well as to a kit for extracting, isolating and/or purifying nucleic acids from a wax-embedded sample.

    摘要翻译: 本发明涉及一种从嵌入蜡的样品中提取核酸的方法,在从交联的蜡 - 样品中提取,分离和/或纯化核酸的方法中使用特定溶剂从蜡包埋的样品中除去蜡, 嵌入样品以及用于从蜡嵌入样品中提取,分离和/或纯化核酸的试剂盒。

    METHOD AND DEVICE FOR ISOLATING AND PURIFYING DOUBLE-STRANDED NUCLEIC ACIDS
    6.
    发明申请
    METHOD AND DEVICE FOR ISOLATING AND PURIFYING DOUBLE-STRANDED NUCLEIC ACIDS 有权
    用于分离和纯化双链核酸的方法和装置

    公开(公告)号:US20130237699A1

    公开(公告)日:2013-09-12

    申请号:US13884416

    申请日:2011-11-08

    IPC分类号: C07H1/08 B01D15/34

    摘要: The invention relates to a chromatographic device for isolating and/or purifying double-stranded nucleic acids, preferably double-stranded DNA, from a mixture of such nucleic acids with single-stranded nucleic acids, oligonucleotides, mononucleotides, salts and/or other such impurities. The invention also relates to a method for chromatographically isolating and/or purifying same, and to a kit for this purpose.

    摘要翻译: 本发明涉及用于从这种核酸与单链核酸,寡核苷酸,单核苷酸,盐和/或其它这些杂质的混合物中分离和/或纯化双链核酸,优选双链DNA的色谱装置 。 本发明还涉及用于色谱分离和/或纯化的方法以及用于该目的的试剂盒。

    Rotor For A Centrifuge
    7.
    发明申请
    Rotor For A Centrifuge 审中-公开
    转子转子离心机

    公开(公告)号:US20110224063A1

    公开(公告)日:2011-09-15

    申请号:US13124348

    申请日:2009-10-13

    申请人: Thorsten Singer

    发明人: Thorsten Singer

    IPC分类号: B04B5/04 B01D21/26

    摘要: An apparatus (10) for a centrifuge for isolating and/or purifying biomolecules has a rotor body (12) for rotatable mounting around a rotation axis in the centrifuge. According to the invention, the rotor body (12) has in addition at least one channel (14) for channeling a sample liquid. The integration of the channel (14) into the rotor body (12) simplifies the isolation and/or purification process, and the longer usable path for separating samples leads to improved separation.

    摘要翻译: 用于分离和/或净化生物分子的离心机的设备(10)具有用于在离心机内围绕旋转轴线旋转安装的转子体(12)。 根据本发明,转子体(12)还具有用于引导样品液体的至少一个通道(14)。 通道(14)与转子主体(12)的集成简化了隔离和/或净化过程,并且用于分离样品的更长的可用路径导致改进的分离。

    Method and device for isolating and purifying double-stranded nucleic acids
    8.
    发明授权
    Method and device for isolating and purifying double-stranded nucleic acids 有权
    用于分离和纯化双链核酸的方法和装置

    公开(公告)号:US09458452B2

    公开(公告)日:2016-10-04

    申请号:US13884416

    申请日:2011-11-08

    摘要: The invention relates to a chromatographic device for isolating and/or purifying double-stranded nucleic acids, preferably double-stranded DNA, from a mixture of such nucleic acids with single-stranded nucleic acids, oligonucleotides, mononucleotides, salts and/or other such impurities. The invention also relates to a method for chromatographically isolating and/or purifying same, and to a kit for this purpose.

    摘要翻译: 本发明涉及用于从这种核酸与单链核酸,寡核苷酸,单核苷酸,盐和/或其它这些杂质的混合物中分离和/或纯化双链核酸,优选双链DNA的色谱装置 。 本发明还涉及用于色谱分离和/或纯化的方法以及用于该目的的试剂盒。

    Method for Cleaning and Isolating Nucleic Using Cationic Detergents
    9.
    发明申请
    Method for Cleaning and Isolating Nucleic Using Cationic Detergents 有权
    使用阳离子洗涤剂清洗和分离核的方法

    公开(公告)号:US20080113348A1

    公开(公告)日:2008-05-15

    申请号:US11572085

    申请日:2005-07-15

    申请人: Thorsten Singer

    发明人: Thorsten Singer

    IPC分类号: C12Q1/68 C12N1/08

    CPC分类号: C12N15/101

    摘要: The present invention relates to a method for cleaning and isolating nucleic acids using cationic detergents with the general formula (I): Y+R1R2R3R4X−   (I) where Y can represent nitrogen or phosphorus R1, R2, R3 and R4 can represent independently from one another an unbranched or branched C1-C20-alkyl residue, C3-C6-alkenyl residue, C3-C6-alkinyl residue and/or a C6-C20-aryl residue as well as a C6-C26-aralkyl residue, and X— can represent an anion of an inorganic or organic single or multi-basic acid.

    摘要翻译: 本发明涉及一种使用具有通式(I)的阳离子去污剂来清洗和分离核酸的方法:<?在线公式描述=“在线公式”end =“lead”→> 其中R 1,R 2,R 2,R 3,R 3,R 3,R 3, (I)<?in-line-formula description =“In-line formula”end =“tail”?>其中Y可以表示氮或磷R 1,R 2 ,R 3和R 4可以彼此独立地表示无支链或支链C 1 -C 20烷基, - 烷基残基,C 3 -C 6 - 链烯基残基,C 3 -C 6 - 炔基残基和C 3 -C 6 - /或C 6 -C 20 - 芳基以及C 6 -C 26 - 芳烷基 残基和X-可以代表无机或有机单碱或多碱的阴离子。